• 20770 Citations
  • 80 Scopus h-Index
1974 …2020

Research output per year

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Research Output

Factors controlling muscle protein synthesis and degradation

Nair, K. S. & Schwenk, W. F., 1994, In : Current opinion in neurology. 7, 5, p. 471-474 4 p.

Research output: Contribution to journalReview article

3 Scopus citations

Failure of carbohydrate to spare leucine oxidation in obese subjects

Nair, K. S., Halliday, D., Ford, G. C., Heels, S. & Garrow, J. S., Dec 1 1987, In : International Journal of Obesity. 11, 5, p. 537-544 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
16 Scopus citations

Failure of glyburide and insulin treatment to decrease leucine flux in obese type II diabetic patients

Welle, S. & Nair, K. S., 1990, In : International Journal of Obesity. 14, 8, p. 701-710 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Failure of insulin infusion to stimulate fractional muscle protein synthesis in type I diabetic patients. Anabolic effect of insulin and decreased proteolysis

Pacy, P. J., Nair, K. S., Ford, C. & Halliday, D., Jan 1 1989, In : Diabetes. 38, 5, p. 618-624 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling

Vendelbo, M. H., Møller, A. B., Christensen, B., Nellemann, B., Clasen, B. F. F., Nair, K. S., Jørgensen, J. O. L., Jessen, N. & Møller, N., Jul 14 2014, In : PloS one. 9, 7, e102031.

Research output: Contribution to journalArticle

32 Scopus citations

Fatty acid metabolism in the elderly: Effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women

Koutsari, C., Ali, A. H., Nair, K. S., Rizza, R. A., O'Brien, P., Khosla, S. & Jensen, M. D., Sep 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

First and second trimester urinary metabolic profiles and fetal growth restriction: An exploratory nested case-control study within the infant development and environment study

Luthra, G., Vuckovic, I., Bangdiwala, A., Gray, H., Redmon, J. B., Barrett, E. S., Sathyanarayana, S., Nguyen, R. H. N., Swan, S. H., Zhang, S., Dzeja, P., Macura, S. I. & Nair, K. S., Feb 8 2018, In : BMC Pregnancy and Childbirth. 18, 1, 48.

Research output: Contribution to journalArticle

4 Scopus citations

FOXO3A regulates BNIP3 and modulates mitochondrial calcium, dynamics, and function in cardiac stress

Chaanine, A. H., Kohlbrenner, E., Gamb, S. I., Guenzel, A. J., Klaus, K., Fayyaz, A. U., Sreekumaran Nair, K., Hajjar, R. J. & Redfield, M. M., Dec 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 6, p. H1540-H1559

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

FOXO transcription factors are critical regulators of diabetes-related muscle atrophy

O’Neill, B. T., Bhardwaj, G., Penniman, C. M., Krumpoch, M. T., Suarez Beltran, P. A., Klaus, K., Poro, K., Li, M., Pan, H., Dreyfuss, J. M., Sreekumaran Nair, K. & Ronald Kahn, C., Mar 1 2019, In : Diabetes. 68, 3, p. 556-570 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

Frailty and its potential relevance to cardiovascular care

Singh, M., Alexander, K., Roger, V. L., Rihal, C. S., Whitson, H. E., Lerman, A., Jahangir, A. & Nair, K. S., Oct 2008, In : Mayo Clinic proceedings. 83, 10, p. 1146-1153 8 p.

Research output: Contribution to journalReview article

70 Scopus citations

Functional and proteomic alterations of plasma high density lipoproteins in type 1 diabetes mellitus

Manjunatha, S., Distelmaier, K., Dasari, S., Carter, R. E., Kudva, Y. C. & Nair, K. S., Sep 1 2016, In : Metabolism: Clinical and Experimental. 65, 9, p. 1421-1431 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Functional heterogeneity of leucine pools in human skeletal muscle

Ljungqvist, O. H., Persson, M., Charles Ford, G. & Sreekumaran Nair, K., Dec 1 1997, In : American Journal of Physiology. 273, 3 PART 1, p. E521-E527

Research output: Contribution to journalArticle

8 Scopus citations

Functional heterogeneity of leucine pools in human skeletal muscle

Ljungqvist, O. H., Persson, M., Ford, G. C. & Nair, K. S., Sep 1997, In : American Journal of Physiology - Endocrinology and Metabolism. 273, 3 36-3, p. E564-E570

Research output: Contribution to journalArticle

83 Scopus citations

Functional impact of high protein intake on healthy elderly people

Walrand, S., Short, K. R., Bigelow, M. L., Sweatt, A. J., Hutson, S. M. & Nair, K. S., Oct 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 4, p. E921-E928

Research output: Contribution to journalArticle

79 Scopus citations

Function-based discovery of significant transcriptional temporal patterns in insulin stimulated muscle cells

Di Camillo, B., Irving, B. A., Schimke, J., Sanavia, T., Toffolo, G., Cobelli, C. & Nair, K. S., Mar 1 2012, In : PloS one. 7, 3, e32391.

Research output: Contribution to journalArticle

8 Scopus citations

GDF15 mediates the effects of metformin on body weight and energy balance

Coll, A. P., Chen, M., Taskar, P., Rimmington, D., Patel, S., Tadross, J. A., Cimino, I., Yang, M., Welsh, P., Virtue, S., Goldspink, D. A., Miedzybrodzka, E. L., Konopka, A. R., Esponda, R. R., Huang, J. T. J., Tung, Y. C. L., Rodriguez-Cuenca, S., Tomaz, R. A., Harding, H. P., Melvin, A. & 13 others, Yeo, G. S. H., Preiss, D., Vidal-Puig, A., Vallier, L., Nair, K. S., Wareham, N. J., Ron, D., Gribble, F. M., Reimann, F., Sattar, N., Savage, D. B., Allan, B. B. & O’Rahilly, S., Feb 20 2020, In : Nature. 578, 7795, p. 444-448 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment

Sreekumar, R., Halvatsiotis, P., Schimke, J. C. & Sreekumaran Nair, K., 2002, In : Diabetes. 51, 6, p. 1913-1920 8 p.

Research output: Contribution to journalArticle

Open Access
208 Scopus citations

Glutamine-derived 2-hydroxyglutarate is associated with disease progression in plasma cell malignancies

Gonsalves, W. I., Ramakrishnan, V., Hitosugi, T., Ghosh, T., Jevremovic, D., Dutta, T., Sakrikar, D., Petterson, X. M., Wellik, L., Kumar, S. K. & Nair, K. S., Jan 11 2018, In : JCI Insight. 3, 1

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

White, J. P., Wrann, C. D., Rao, R. R., Nair, S. K., Jedrychowski, M. P., You, J. S., Martínez-Redondo, V., Gygi, S. P., Ruas, J. L., Hornberger, T. A., Wu, Z., Glass, D. J., Piao, X. & Spiegelman, B. M., Nov 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 44, p. 15756-15761 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Growth Hormone Effects on Protein Metabolism

Møller, N., Copeland, K. C. & Nair, K. S., Mar 1 2007, In : Endocrinology and Metabolism Clinics of North America. 36, 1, p. 89-100 12 p.

Research output: Contribution to journalReview article

16 Scopus citations

Heated dorsal hand vein sampling for metabolic studies: A reappraisal

Copeland, K. C., Kenney, F. A. & Nair, K. S., 1992, In : American Journal of Physiology - Endocrinology and Metabolism. 263, 5 26-5, p. E1010-E1014

Research output: Contribution to journalArticle

97 Scopus citations

Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements

Henderson, G. C., Dhatariya, K., Ford, G. C., Klaus, K. A., Basu, R., Rizza, R. A., Jensen, M. D., Khosla, S., O'Brien, P. & Nair, K. S., Feb 2009, In : FASEB Journal. 23, 2, p. 631-641 11 p.

Research output: Contribution to journalArticle

64 Scopus citations

Higher unacylated ghrelin and insulin sensitivity following dietary restriction and weight loss in obese humans

Barazzoni, R., Gortan Cappellari, G., Zanetti, M., Klaus, K. A., Semolic, A., Johnson, M. L. & Nair, K. S., 2020, (Accepted/In press) In : Clinical Nutrition.

Research output: Contribution to journalArticle

High insulin combined with essential amino acids stimulates skeletal muscle mitochondrial protein synthesis while decreasing insulin sensitivity in healthy humans

Robinson, M. M., Soop, M., Sohn, T. S., Morse, D. M., Schimke, J. M., Klaus, K. A. & Nair, K. S., Dec 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 12, p. E2574-E2583

Research output: Contribution to journalArticle

31 Scopus citations

High-performance liquid chromatographic technique for non-derivatized leucine purification: evidence for carbon isotope fractionation

Baumann, P. Q., Ebenstein, D. B., O'Rourke, B. D. & Nair, K. S., Jan 3 1992, In : Journal of Chromatography B: Biomedical Sciences and Applications. 573, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Hormonal and signaling role of branched-chain amino acids

Nair, K. S. & Short, K. R., Jun 2005, In : Journal of Nutrition. 135, 6 SUPPL., p. 1547S-1552S

Research output: Contribution to journalArticle

Open Access
86 Scopus citations

Hormonal regulation of human muscle protein metabolism

Rooyackers, O. E. & Nair, K. S., 1997, In : Annual Review of Nutrition. 17, p. 457-485 29 p.

Research output: Contribution to journalReview article

156 Scopus citations

Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?

Giannoulis, M. G., Martin, F. C., Nair, K. S., Umpleby, A. M. & Sonksen, P., Jun 2012, In : Endocrine reviews. 33, 3, p. 314-377 64 p.

Research output: Contribution to journalReview article

70 Scopus citations

Hyperandrogenism sensitizes leukocytes to hyperglycemia to promote oxidative stress in lean reproductive-age women

González, F., Nair, K. S., Daniels, J. K., Basal, E., Schimke, J. M. & Blair, H. E., Aug 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2836-2843 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Hyperandrogenism sensitizes mononuclear cells to promote glucose-induced inflammation in lean reproductive-age women

González, F., Sreekumaran Nair, K., Daniels, J. K., Basal, E. & Schimke, J. M., Feb 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 3, p. 297-306 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Hyperglucagonemia during insulin deficiency accelerates protein catabolism

Sreekumaran Nair, K., Halliday, D., Matthews, D. E. & Welle, S. L., Dec 1 1987, In : American Journal of Physiology - Endocrinology and Metabolism. 253, 2, p. 16/2

Research output: Contribution to journalArticle

52 Scopus citations
82 Scopus citations

Hyperglucagonemia Mitigates the Effect of Metformin on Glucose Production in Prediabetes

Konopka, A. R., Esponda, R. R., Robinson, M. M., Johnson, M. L., Carter, R. E., Schiavon, M., Cobelli, C., Wondisford, F. E., Lanza, I. R. & Nair, K. S., May 17 2016, In : Cell reports. 15, 7, p. 1394-1400 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Identification of amadori-modified plasma proteins in type 2 diabetes and the effect of short-term intensive insulin treatment

Jaleel, A., Halvatsiotis, P., Willlamson, B., Juhasz, P., Martin, S. & Nair, K. S., Mar 2005, In : Diabetes care. 28, 3, p. 645-652 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Identification of de novo synthesized and relatively older proteins: Accelerated oxidative damage to de novo synthesized apolipoprotein A-1 in type 1 diabetes

Jaleel, A., Henderson, G. C., Madden, B. J., Klaus, K. A., Morse, D. M., Gopala, S. & Nair, K. S., Oct 2010, In : Diabetes. 59, 10, p. 2366-2374 9 p.

Research output: Contribution to journalArticle

38 Scopus citations
9 Scopus citations

Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity

Short, K. R., Vittone, J. L., Bigelow, M. L., Proctor, D. N., Rizza, R. A., Coenen-Schimke, J. M. & Nair, K. S., Aug 1 2003, In : Diabetes. 52, 8, p. 1888-1896 9 p.

Research output: Contribution to journalArticle

435 Scopus citations

Impact of endurance training on murine spontaneous activity, muscle mitochondrial DNA abundance, gene transcripts, and function

Chow, L. S., Greenlund, L. J., Asmann, Y. W., Short, K. R., McCrady, S. K., Levine, J. A. & Nair, K. S., Mar 2007, In : Journal of applied physiology. 102, 3, p. 1078-1089 12 p.

Research output: Contribution to journalArticle

61 Scopus citations

Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients

Østergård, T., Andersen, J. L., Nyholm, B., Lund, S., Nair, K. S., Saltin, B. & Schmitz, O., May 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 290, 5, p. E998-E1005

Research output: Contribution to journalArticle

62 Scopus citations

Impact of high-fat diet and antioxidant supplement on mitochondrial functions and gene transcripts in rat muscle

Sreekumar, R., Unnikrishnan, J., Fu, A., Nygren, J., Short, K. R., Schimke, J., Barazzoni, R. & Nair, K. S., 2002, In : American Journal of Physiology - Endocrinology and Metabolism. 282, 5 45-5, p. E1055-E1061

Research output: Contribution to journalArticle

102 Scopus citations

Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice

Zabielski, P., Blachnio-Zabielska, A., Lanza, I. R., Gopala, S., Manjunatha, S., Jakaitis, D. R., Persson, X. M., Gransee, J., Klaus, K. A., Schimke, J. M., Jensen, M. D. & Nair, K. S., 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 5, p. E529-E542

Research output: Contribution to journalArticle

15 Scopus citations

Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people

Dutta, T., Kudva, Y. C., Persson, X. M. T., Schenck, L. A., Charles Ford, G., Singh, R. J., Carter, R. & Sreekumaran Nair, K., Mar 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 4, p. 1023-1033 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Impact of total body water errors on Kt/V estimates in children on peritoneal dialysis.

Morgenstern, B., Nair, K. S., Lerner, G., Neu, A., Quan, A. & Warady, B. A., 2001, In : Advances in peritoneal dialysis. Conference on Peritoneal Dialysis. 17, p. 260-263 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Impact of type 1 diabetes and insulin treatment on plasma levels and fractional synthesis rate of retinol-binding protein 4

Jourdan, M., Jaleel, A., Karakelides, H., Ford, G. C., Kahn, B. B. & Nair, K. S., Dec 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 5125-5130 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Impaired mitochondrial activity and insulin-resistant offspring of patients with type 2 diabetes [5] (multiple letters)

Short, K. R., Nair, K. S., Stump, C. S., Bajaj, M., Mandarino, L. J., Raubenheimer, P. J., Möhlig, M., Isken, F., Ristow, M., Petersen, K. F. & Shulman, G. I., Jun 3 2004, In : New England Journal of Medicine. 350, 23, p. 2419-2421 3 p.

Research output: Contribution to journalLetter

32 Scopus citations

Impairment of phenylalanine conversion to tyrosine in end-stage renal disease causing tyrosine deficiency

Boirie, Y., Albright, R., Bigelow, M. & Nair, K. S., Aug 2004, In : Kidney international. 66, 2, p. 591-596 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
12 Scopus citations

Increased concentration of tracee affects estimates of muscle protein synthesis

Caso, G., Ford, G. C., Sreekumaran Nair, K., Vosswinkel, J. A., Garlick, P. J. & McNurlan, M. A., 2001, In : American Journal of Physiology - Endocrinology and Metabolism. 280, 6 43-6, p. E937-E946

Research output: Contribution to journalArticle

21 Scopus citations

Increased energy expenditure in poorly controlled Type 1 (insulin-dependent) diabetic patients

Nair, K. S., Halliday, D. & Garrow, J. S., Jul 1 1984, In : Diabetologia. 27, 1, p. 13-16 4 p.

Research output: Contribution to journalArticle

Open Access
88 Scopus citations