• 22571 Citations
  • 57 Scopus h-Index
1982 …2020

Research output per year

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Research Output

1982

Effects of ketamine-xylazine anesthesia on blood levels of luteinizing hormone and follicle stimulating hormone in rabbits

Mills, T. M. & Copland, J. A., Dec 1 1982, In : Laboratory animal science. 32, 6, p. 619-621 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Factors affecting the postovulatory secretion of FSH in the rabbit

Mills, T. M. & Copland, J. A., Jan 1 1982, In : Biology of Reproduction. 26, Suppl. 1 (, p. No. 236

Research output: Contribution to journalArticle

1983
Open Access
1 Scopus citations

Is the postovulatory release of follicle-stimulating hormone in the rabbit mediated by luteinizing hormone-releasing hormone?

Mills, T. M., Copland, J. A., Coy, D. H. & Schally, A. V., Sep 1983, In : Endocrinology. 113, 3, p. 1020-1024 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
1984

Cryptic estrogen binding protein complicates analysis of estrogen receptor distribution

Smanik, E. J., Copland, J. A. & Muldoon, T. G., Dec 14 1984, In : Biochemical and Biophysical Research Communications. 125, 2, p. 577-583 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
1987
14 Scopus citations

Inhibition of spontaneous mouse mammary tumour development by Antineoplaston A10

Muldoon, T. G., Copland, J. A., Lehner, A. F. & Hendry, L. B., Jan 1 1987, In : Drugs under Experimental and Clinical Research. 13, SUPPL. 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Stereochemical modelling studies of the interaction of Antineoplaston A10 with DNA

Hendry, L. B., Muldoon, T. G., Burzynski, S. R., Copland, J. A. & Lehner, A. F., May 12 1987, In : Drugs under Experimental and Clinical Research. 13, SUPPL. 1, p. 77-81 5 p.

Research output: Contribution to journalArticle

19 Scopus citations
1991

3-Phenylacetylamino-2, 6-Piperidinedione Inhibition of Rat Nb2 Lymphoma Cell Mitogenesis

Wood, J. C., Copland, J. A., Muldoon, T. G. & Hendry, L. B., Sep 1991, In : Proceedings of the Society for Experimental Biology and Medicine. 197, 4, p. 404-408 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
1993

Inhibition of estrogen stimulated mitogenesis by 3-phenylacetylamino-2,6-piperidinedione and its Para-hydroxy analog

Copland, J. A., Hendry, L. B., Chu, C. K., Wood, J. C., Wrenn, R. W., Pantazis, C. G. & Mahesh, V. B., Oct 1993, In : Journal of Steroid Biochemistry and Molecular Biology. 46, 4, p. 451-462 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
1994

Antiestrogenic piperidinediones designed prospectively using computer graphics and energy calculations of DNA-ligand complexes

Hendry, L. B., Chu, C. K., Copland, J. A. & Mahesh, V. B., Apr 1994, In : Journal of Steroid Biochemistry and Molecular Biology. 48, 5-6, p. 495-505 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Design of novel antiestrogens

Hendry, L. B., Chu, C. K., Rosser, M. L., Copland, J. A., Wood, J. C. & Mahesh, V. B., Jun 1994, In : Journal of Steroid Biochemistry and Molecular Biology. 49, 4-6, p. 269-280 12 p.

Research output: Contribution to journalArticle

24 Scopus citations
1996

Molecular cloning and functional characterization of the oxytocin receptor from a rat pancreatic cell line (RINm5F)

Jeng, Y. J., Lolait, S. J., Strakova, Z., Chen, C., Copland, J. A., Mellman, D., Hellmich, M. R. & Soloff, M. S., Jan 1 1996, In : Neuropeptides. 30, 6, p. 557-565 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
1998

ERK2 mediates oxytocin-stimulated PGE2 synthesis

Strakova, Z., Copland, J. A., Lolait, S. J. & Soloff, M. S., Apr 1998, In : American Journal of Physiology - Endocrinology and Metabolism. 274, 4 37-4, p. E634-E641

Research output: Contribution to journalArticle

66 Scopus citations
1999

Demonstration of functional oxytocin receptors in human breast Hs578T cells and their up-regulation through a protein kinase C-dependent pathway

Copland, J. A., Jeng, Y. J., Strakova, Z., Ives, K. L., Hellmich, M. R. & Soloff, M. S., Jan 1 1999, In : Endocrinology. 140, 5, p. 2258-2267 10 p.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

Functional oxytocin receptors discovered in human osteoblasts

Copland, J. A., Ives, K. L., Simmons, D. J. & Soloff, M. S., Jan 1 1999, In : Endocrinology. 140, 9, p. 4371-4374 4 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Identification of a GABPα/β binding site involved in the induction of oxytocin receptor gene expression in human breast cells. Potentiation by c-Fos/c-Jun

Hoare, S., Copland, J. A., Wood, T. G., Jeng, Y. J., Izban, M. G. & Soloff, M. S., Jan 1 1999, In : Endocrinology. 140, 5, p. 2268-2279 12 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

The proximal portion of the COOH terminus of the oxytocin receptor is required for coupling to G(q), but not G(i). Independent mechanisms for elevating intracellular calcium concentrations from intracellular stores

Hoare, S., Copland, J. A., Strakova, Z., Ives, K., Jeng, Y. J., Hellmich, M. R. & Soloff, M. S., Oct 1 1999, In : Journal of Biological Chemistry. 274, 40, p. 28682-28689 8 p.

Research output: Contribution to journalArticle

63 Scopus citations
2000

A novel glucocorticoid receptor binding element within the murine c-myc promoter

Ma, T., Copland, J. A., Brasier, A. R. & Thompson, E. A., Jan 1 2000, In : Molecular Endocrinology. 14, 9, p. 1377-1386 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Functional oxytocin receptors in a human endometrial cell line

Zlatnik, M. G., Copland, J. A., Ives, K. & Soloff, M. S., Apr 2000, In : American journal of obstetrics and gynecology. 182, 4, p. 850-855 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pregnancy, parturition, and prostaglandins: Defining uterine leiomyomas

Cesen-Cummings, K., Copland, J. A., Barrett, J. C., Walker, C. L. & Davis, B. J., Jan 1 2000, In : Environmental Health Perspectives. 108, SUPPL. 5, p. 817-820 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

Signal pathways mediating oxytocin stimulation of prostaglandin synthesis in select target cells

Soloff, M. S., Jeng, Y. J., Copland, J. A., Strakova, Z. & Hoare, S., Mar 2000, In : Experimental physiology. 85 S, SPEC. ISS., p. 51S-58S

Research output: Contribution to journalReview article

37 Scopus citations
2002

Oxytocin receptor regulation and action in a human granulosa-lutein cell line

Copland, J. A., Zlatnik, M. G., Ives, K. L. & Soloff, M. S., Jan 1 2002, In : Biology of Reproduction. 66, 5, p. 1230-1236 7 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2003

Bioconjugated gold nanoparticles as a contrast agent for optoacoustic detection of small tumors

Eghtedari, M. A., Copland, J. A., Popov, V. L., Kotov, N. A., Motamedi, M. & Oraevsky, A. A., Dec 5 2003, In : Proceedings of SPIE - The International Society for Optical Engineering. 4960, p. 76-85 10 p.

Research output: Contribution to journalConference article

23 Scopus citations

Genomic profiling identifies alterations in TGFβ signaling through loss of TGFβ receptor expression in human renal cell carcinogenesis and progression

Copland, J. A., Luxon, B. A., Ajani, L., Maity, T., Campagnaro, E., Guo, H., LeGrand, S. N., Tamboli, P. & Wood, C. G., Sep 11 2003, In : Oncogene. 22, 39, p. 8053-8062 10 p.

Research output: Contribution to journalArticle

89 Scopus citations

Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor γ ligands in uterine leiomyoma

Houston, K. D., Copland, J. A., Broaddus, R. R., Gottardis, M. M., Fischer, S. M. & Walker, C. L., Mar 15 2003, In : Cancer research. 63, 6, p. 1221-1227 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

The Use of DNA Microarrays to Assess Clinical Samples: The Transition from Bedside to Bench to Bedside

Copland, J. A., Davies, P. J., Shipley, G. L., Wood, C. G., Luxon, B. A. & Urban, R. J., Nov 10 2003, In : Recent Progress in Hormone Research. 58, p. 25-53 29 p.

Research output: Contribution to journalReview article

34 Scopus citations

Uterine leiomyomas express myometrial contractile-associated proteins involved in pregnancy-related hormone signaling

Cesen-Cummings, K., Houston, K. D., Copland, J. A., Moorman, V. J., Walker, C. L. & Davis, B. J., Jan 1 2003, In : Journal of the Society for Gynecologic Investigation. 10, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

28 Scopus citations
2004

Bioconjugated gold nanoparticles as a molecular based contrast agent: Implications for imaging of deep tumors using optoacoustic tomography

Copland, J. A., Eghtedari, M., Popov, V. L., Kotov, N., Mamedova, N., Motamedi, M. & Oraevsky, A. A., Sep 1 2004, In : Molecular Imaging and Biology. 6, 5, p. 341-349 9 p.

Research output: Contribution to journalArticle

282 Scopus citations

Gene therapy of uterine leiomyomas: Adenovirus-mediated expression of dominant negative estrogen receptor inhibits tumor growth in nude mice

Al-Hendy, A., Lee, E. J., Wang, H. Q. & Copland, J. A., Nov 1 2004, In : American journal of obstetrics and gynecology. 191, 5, p. 1621-1631 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Potential nonhormonal therapeutics for medical treatment of leiomyomas

Young, S. L., Al-Hendy, A. & Copland, J. A., May 1 2004, In : Seminars in Reproductive Medicine. 22, 2, p. 121-130 10 p.

Research output: Contribution to journalReview article

22 Scopus citations
2005

Atypical protein kinase Cτ plays a critical role in human lung cancer cell growth and tumorigenicity

Regala, R. P., Weems, C., Jamieson, L., Copland, J. A., Thompson, E. A. & Fields, A. P., Sep 2 2005, In : Journal of Biological Chemistry. 280, 35, p. 31109-31115 7 p.

Research output: Contribution to journalArticle

154 Scopus citations
2006

Expression of estrogen and progesterone receptors in the human endocervix

Al-Hendy, A., Hui, Q. W. & Copland, J. A., Dec 1 2006, In : Middle East Fertility Society Journal. 11, 3, p. 216-221 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates

Law, C. L., Gordon, K. A., Toki, B. E., Yamane, A. K., Hering, M. A., Cerveny, C. G., Petroziello, J. M., Ryan, M. C., Smith, L., Simon, R., Sauter, G., Oflazoglu, E., Doronina, S. O., Meyer, D. L., Francisco, J. A., Carter, P., Senter, P. D., Copland, J. A., Wood, C. G. & Wahl, A. F., Feb 15 2006, In : Cancer research. 66, 4, p. 2328-2337 10 p.

Research output: Contribution to journalArticle

113 Scopus citations

Molecular diagnosis of a BRAF papillary thyroid carcinoma with multiple chromosome abnormalities and rare adrenal and hypothalamic metastases

Copland, J. A., Marlow, L. A., Williams, S. F., Grebe, S. K., Gumz, M. L., Maples, W. J., Silverman, V. E. & Smallridge, R. C., Dec 1 2006, In : Thyroid. 16, 12, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Novel high-affinity PPARγ agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1

Copland, J. A., Marlow, L. A., Kurakata, S., Fujiwara, K., Wong, A. K. C., Kreinest, P. A., Williams, S. F., Haugen, B. R., Klopper, J. P. & Smallridge, R. C., Apr 13 2006, In : Oncogene. 25, 16, p. 2304-2317 14 p.

Research output: Contribution to journalArticle

112 Scopus citations
2007

Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin

Denner, L., Bodenburg, Y., Zhao, J. G., Howe, M., Cappo, J., Tilton, R. G., Copland, J. A., Forraz, N., McGuckin, C. & Urban, R., Jun 2007, In : Cell Proliferation. 40, 3, p. 367-380 14 p.

Research output: Contribution to journalArticle

65 Scopus citations

Functionalized gold nanorods-for molecular optoacoustic imaging

Eghtedari, M., Oraevsky, A., Conjusteau, A., Copland, J. A., Kotov, N. A. & Motamedi, M., Apr 30 2007, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics. 64370G. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 6437).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

High sensitivity of in vivo detection of gold nanorods using a laser optoacoustic imaging system

Eghtedari, M., Oraevsky, A., Copland, J. A., Kotov, N. A., Conjusteau, A. & Motamedi, M., Jul 1 2007, In : Nano Letters. 7, 7, p. 1914-1918 5 p.

Research output: Contribution to journalArticle

324 Scopus citations

IGF-1 controls GLUT3 expression in muscle via the transcriptional factor Sp1

Copland, J. A., Pardini, A. W., Wood, T. G., Yin, D., Green, A., Bodenburg, Y. H., Urban, R. J. & Stuart, C. A., Nov 1 2007, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1769, 11-12, p. 631-640 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Lower expression levels of the transforming growth factor beta receptor type II protein are associated with a less aggressive tumor phenotype and improved survival among patients with clear cell renal cell carcinoma

Parker, A. S., Lohse, C. M., Wu, K., Kreinest, P., Copland, J. A., Hilton, T., Wehle, M., Cheville, J. C. & Blute, M., Mar 1 2007, In : Human Pathology. 38, 3, p. 453-461 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma

Gumz, M. L., Zou, H., Kreinest, P. A., Childs, A. C., Belmonte, L. S., LeGrand, S. N., Wu, K. J., Luxon, B. A., Sinha, M., Parker, A. S., Sun, L. Z., Ahlquist, D. A., Wood, C. G. & Copland, J. A., Aug 15 2007, In : Clinical Cancer Research. 13, 16, p. 4740-4749 10 p.

Research output: Contribution to journalArticle

203 Scopus citations
2008

A p120 catenin isoform switch affects rho activity, induces tumor cell invasion, and predicts metastatic disease

Yanagisawa, M., Huveldt, D., Kreinest, P., Lohse, C. M., Cheville, J. C., Parker, A. S., Copland, J. A. & Anastasiadis, P. Z., Jun 27 2008, In : Journal of Biological Chemistry. 283, 26, p. 18344-18354 11 p.

Research output: Contribution to journalArticle

111 Scopus citations

Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-β1 protein

Kang, J., Lee, M. S., Copland, J. A., Luxon, B. A. & Gorenstein, D. G., Mar 15 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 6, p. 1835-1839 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification

Schweppe, R. E., Klopper, J. P., Korch, C., Pugazhenthi, U., Benezra, M., Knauf, J. A., Fagin, J. A., Marlow, L. A., Copland, J. A., Smallridge, R. C. & Haugen, B. R., Nov 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 11, p. 4331-4341 11 p.

Research output: Contribution to journalArticle

429 Scopus citations

Expression of the type III TGF-β receptor is negatively regulated by TGF-β

Hempel, N., How, T., Cooper, S. J., Green, T. R., Dong, M., Copland, J. A., Wood, C. G. & Blobe, G. C., May 1 2008, In : Carcinogenesis. 29, 5, p. 905-912 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

ONYX-411, a conditionally replicative oncolytic adenovirus, induces cell death in anaplastic thyroid carcinoma cell lines and suppresses the growth of xenograft tumors in nude mice

Reddi, H. V., Madde, P., Reichert-Eberhardt, A. J., Galanis, E. C., Copland, J. A., McIver, B., Grebe, S. K. G. & Eberhardt, N. L., Nov 2008, In : Cancer Gene Therapy. 15, 11, p. 750-757 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression

Soto, E., Yanagisawa, M., Marlow, L. A., Copland, J. A., Perez, E. A. & Anastasiadis, P. Z., Nov 17 2008, In : Journal of Cell Biology. 183, 4, p. 737-749 13 p.

Research output: Contribution to journalArticle

76 Scopus citations

Type III transforming growth factor-β (TGF-β) receptor mediates apoptosis in renal cell carcinoma independent of the canonical TGF-β signaling pathway

Margulis, V., Maity, T., Zhang, X. Y., Cooper, S. J., Copland, J. A. & Wood, C. G., Sep 15 2008, In : Clinical Cancer Research. 14, 18, p. 5722-5730 9 p.

Research output: Contribution to journalArticle

24 Scopus citations
2009

Anaplastic thyroid cancer: Molecular pathogenesis and emerging therapies

Smallridge, R. C., Marlow, L. A. & Copland, J. A., 2009, In : Endocrine-Related Cancer. 16, 1, p. 17-44 28 p.

Research output: Contribution to journalReview article

257 Scopus citations