Projects per year
Fingerprint Dive into the research topics where Guojun D Bu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Low Density Lipoprotein Receptor-Related Protein-1
Medicine & Life Sciences
Alzheimer Disease
Medicine & Life Sciences
Lipoprotein Receptors
Medicine & Life Sciences
LDL Receptors
Medicine & Life Sciences
LDL-Receptor Related Proteins
Medicine & Life Sciences
Amyloid
Medicine & Life Sciences
Apolipoproteins E
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1985 2020
Integrative translational discovery of vascular risk factors in aging and dementia
Bu, G. D., Mangravite, L. & Ertekin-Taner, N.
9/30/15 → 8/31/20
Project: Research project
Cerebral Amyloid Angiopathy
Dementia
Alzheimer Disease
Apolipoproteins E
Amyloid Plaques
ApoE and LRP1 in brain insulin signaling and glucose metabolism (Competitive Renewal)
12/1/09 → 5/31/20
Project: Research project
Apolipoprotein E4
Apolipoproteins E
Dendrites
Lipid Metabolism
Alzheimer Disease
ALZHEIMER'S DISEASE RESEARCH CENTER
Bu, G. D., Robins, L. E. E., Miller, T. M., Miller, J. P., Mintun, M. A., Harris, D., Snider, W., Edwards, D., Hale, S., Storandt, M., Schwartz, A., Miller, J. P., Mann Koepke, K., McKeel, D., Goate, A., Morris, J., Edwards, D., Hale, S., Schwartz, A., Merlie, J., Schmidt, D., Botwinick, J., Fagan, A., Denny, A., Willard, M., Toga, A., Musiek, E. S., Fulling, K., Cirrito, J., Robins, L. E. E., Schlesinger, M., Carr, D., O'Malley, K., Fischbach, G., Peck, W., Price, J., Olney, J., Berg, L., Snider, W., Miller, J. P., Mann Koepke, K., Buckner, R., Johnson, E., Holtzman, D., Cairns, N. J., Perrin, R. J., Galvin, J., Xiong, C., Miller, T. M., Goate, A., Morris, J., Kopan, R., Miller, J. P., Mintun, M. A., Meuser, T., Harris, D., McKeel, D., Miller, T. M. & Mintun, M. A.
9/30/85 → 4/30/20
Project: Research project
Apolipoprotein E4
Apolipoprotein E3
Apolipoproteins E
Alzheimer Disease
Protein Isoforms
Research Output 1992 2019
5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway
Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C-C., Kanekiyo, T. & Bu, G. D., Mar 2 2019, In : International Journal of Molecular Sciences. 20, 6, 1488.Research output: Contribution to journal › Article
Open Access
Serotonin 5-HT3 Receptor Antagonists
Ondansetron
secretions
Apolipoproteins E
liver
2
Citations
(Scopus)
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1
Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.Research output: Contribution to journal › Article
LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
Corrigendum to “Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease” [EBioMedicine 2 (2015) 294–305] (Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease (2015) 2(4) (294–305), (S2352396415000729), (10.1016/j.ebiom.2015.03.009))
Zhang, L., Zhang, S., Maezawa, I., Trushin, S., Minhas, P., Pinto, M., Jin, L. W., Prasain, K., Nguyen, T. D. T., Yamazaki, Y., Kanekiyo, T., Bu, G. D., Gateno, B., Chang, K. O., Nath, K. A., Nemutlu, E., Dzeja, P. P., Pang, Y-P., Hua, D. H. & Trushina, E. D., Apr 1 2019, In : EBioMedicine. 42, 1 p.Research output: Contribution to journal › Comment/debate
Open Access
Brain
Alzheimer Disease
Animals
Animal Models
Modulation
Erratum: Correction: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System (PLoS biology (2011) 9 1 (e1000575))
Liu, Q., Zhang, J., Zerbinatti, C., Zhan, Y., Kolber, B. J., Herz, J., Muglia, L. J. & Bu, G. D., Jun 1 2019, In : PLoS biology. 17, 6, p. e3000310Research output: Contribution to journal › Comment/debate
Open Access
Lipoprotein Receptors
Systems Biology
Neurology
Leptin
leptin
1
Citation
(Scopus)
Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression
Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., Dickson, D. W., Kanekiyo, T. & Bu, G. D., Apr 1 2019, In : Brain : a journal of neurology. 142, 4, p. 1077-1092 16 p.Research output: Contribution to journal › Article
Tight Junction Proteins
Disease Progression
Alzheimer Disease
Amyloid
Brain