• 16123 Citations
  • 72 Scopus h-Index
1985 …2020
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Fingerprint Dive into the research topics where Guojun D Bu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Low Density Lipoprotein Receptor-Related Protein-1 Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Lipoprotein Receptors Medicine & Life Sciences
LDL Receptors Medicine & Life Sciences
LDL-Receptor Related Proteins Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Apolipoproteins E Medicine & Life Sciences
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1985 2020

Integrative translational discovery of vascular risk factors in aging and dementia

Bu, G. D., Mangravite, L. & Ertekin-Taner, N.

National Institutes of Health

9/30/158/31/20

Project: Research project

Cerebral Amyloid Angiopathy
Dementia
Alzheimer Disease
Apolipoproteins E
Amyloid Plaques
Apolipoprotein E4
Apolipoproteins E
Dendrites
Lipid Metabolism
Alzheimer Disease

ALZHEIMER'S DISEASE RESEARCH CENTER

Bu, G. D., Robins, L. E. E., Miller, T. M., Miller, J. P., Mintun, M. A., Harris, D., Snider, W., Edwards, D., Hale, S., Storandt, M., Schwartz, A., Miller, J. P., Mann Koepke, K., McKeel, D., Goate, A., Morris, J., Edwards, D., Hale, S., Schwartz, A., Merlie, J., Schmidt, D., Botwinick, J., Fagan, A., Denny, A., Willard, M., Toga, A., Musiek, E. S., Fulling, K., Cirrito, J., Robins, L. E. E., Schlesinger, M., Carr, D., O'Malley, K., Fischbach, G., Peck, W., Price, J., Olney, J., Berg, L., Snider, W., Miller, J. P., Mann Koepke, K., Buckner, R., Johnson, E., Holtzman, D., Cairns, N. J., Perrin, R. J., Galvin, J., Xiong, C., Miller, T. M., Goate, A., Morris, J., Kopan, R., Miller, J. P., Mintun, M. A., Meuser, T., Harris, D., McKeel, D., Miller, T. M. & Mintun, M. A.

National Institutes of Health

9/30/854/30/20

Project: Research project

Apolipoprotein E4
Apolipoprotein E3
Apolipoproteins E
Alzheimer Disease
Protein Isoforms

Research Output 1992 2019

5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway

Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C-C., Kanekiyo, T. & Bu, G. D., Mar 2 2019, In : International Journal of Molecular Sciences. 20, 6, 1488.

Research output: Contribution to journalArticle

Open Access
Serotonin 5-HT3 Receptor Antagonists
Ondansetron
secretions
Apolipoproteins E
liver
2 Citations (Scopus)

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
Open Access
Brain
Alzheimer Disease
Animals
Animal Models
Modulation

Erratum: Correction: Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System (PLoS biology (2011) 9 1 (e1000575))

Liu, Q., Zhang, J., Zerbinatti, C., Zhan, Y., Kolber, B. J., Herz, J., Muglia, L. J. & Bu, G. D., Jun 1 2019, In : PLoS biology. 17, 6, p. e3000310

Research output: Contribution to journalComment/debate

Open Access
Lipoprotein Receptors
Systems Biology
Neurology
Leptin
leptin
1 Citation (Scopus)

Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression

Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., Dickson, D. W., Kanekiyo, T. & Bu, G. D., Apr 1 2019, In : Brain : a journal of neurology. 142, 4, p. 1077-1092 16 p.

Research output: Contribution to journalArticle

Tight Junction Proteins
Disease Progression
Alzheimer Disease
Amyloid
Brain