Projects per year
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Dive into the research topics where Guojun D Bu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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TREM2-mediated microglial dynamic function in Alzheimer disease
2/1/20 → 12/31/22
Project: Research project
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Biology and pathobiology of apoE in aging and Alzheimer's disease
Bu, G. D., Asmann, Y., Bowman, G. & Dickson, D. W.
6/1/21 → 5/31/22
Project: Research project
Research output
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APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer’s disease with Lewy body pathology
Jin, Y., Li, F., Sonoustoun, B., Kondru, N. C., Martens, Y. A., Qiao, W., Heckman, M. G., Ikezu, T. C., Li, Z., Burgess, J. D., Amerna, D., O’Leary, J., DeTure, M. A., Zhao, J., McLean, P. J., Dickson, D. W., Ross, O. A., Bu, G. & Zhao, N., 2022, (Accepted/In press) In: Acta neuropathologica.Research output: Contribution to journal › Article › peer-review
Open Access -
ApoE4 reduction: An emerging and promising therapeutic strategy for Alzheimer's disease
Li, Y., Macyczko, J. R., Liu, C. C. & Bu, G., Jul 2022, In: Neurobiology of aging. 115, p. 20-28 9 p.Research output: Contribution to journal › Review article › peer-review
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ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias
Martens, Y. A., Zhao, N., Liu, C. C., Kanekiyo, T., Yang, A. J., Goate, A. M., Holtzman, D. M. & Bu, G., Apr 20 2022, In: Neuron. 110, 8, p. 1304-1317 14 p.Research output: Contribution to journal › Review article › peer-review
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Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities
Syrjanen, J. A., Campbell, M. R., Algeciras-Schimnich, A., Vemuri, P., Graff-Radford, J., Machulda, M. M., Bu, G., Knopman, D. S., Jack, C. R., Petersen, R. C. & Mielke, M. M., Jun 2022, In: Alzheimer's and Dementia. 18, 6, p. 1128-1140 13 p.Research output: Contribution to journal › Article › peer-review
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Brain integrity is altered by hepatic APOE ε4 in humanized-liver mice
Giannisis, A., Patra, K., Edlund, A. K., Nieto, L. A., Benedicto-Gras, J., Moussaud, S., de la Rosa, A., Twohig, D., Bengtsson, T., Fu, Y., Bu, G., Bial, G., Foquet, L., Hammarstedt, C., Strom, S., Kannisto, K., Raber, J., Ellis, E. & Nielsen, H. M., 2022, (Accepted/In press) In: Molecular Psychiatry.Research output: Contribution to journal › Article › peer-review
Open Access