Projects per year
Fingerprint Dive into the research topics where Guojun D Bu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Alzheimer Disease
Medicine & Life Sciences
Low Density Lipoprotein Receptor-Related Protein-1
Medicine & Life Sciences
LDL Receptors
Medicine & Life Sciences
Lipoprotein Receptors
Medicine & Life Sciences
Amyloid
Medicine & Life Sciences
Apolipoproteins E
Medicine & Life Sciences
LDL-Receptor Related Proteins
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1985 2020
Integrative translational discovery of vascular risk factors in aging and dementia
Bu, G. D., Mangravite, L., Ertekin-Taner, N. & Bu, G. D.
9/30/15 → 8/31/20
Project: Research project
Cerebral Amyloid Angiopathy
Dementia
Alzheimer Disease
Apolipoproteins E
Amyloid Plaques
ApoE and LRP1 in brain insulin signaling and glucose metabolism (Competitive Renewal)
12/1/09 → 5/31/20
Project: Research project
Apolipoprotein E4
Apolipoproteins E
Dendrites
Lipid Metabolism
Alzheimer Disease
ALZHEIMER'S DISEASE RESEARCH CENTER
Bu, G. D., Robins, L. E. E., Miller, T. M., Miller, J. P., Mintun, M. A., Harris, D., Snider, W., Edwards, D., Hale, S., Storandt, M., Schwartz, A., Miller, J. P., Mann Koepke, K., McKeel, D., Goate, A., Morris, J., Edwards, D., Hale, S., Schwartz, A., Merlie, J., Schmidt, D., Botwinick, J., Fagan, A., Denny, A., Willard, M., Toga, A., Musiek, E. S., Fulling, K., Cirrito, J., Robins, L. E. E., Schlesinger, M., Carr, D., O'Malley, K., Fischbach, G., Peck, W., Price, J., Olney, J., Berg, L., Snider, W., Miller, J. P., Mann Koepke, K., Buckner, R., Johnson, E., Holtzman, D., Cairns, N. J., Perrin, R. J., Galvin, J., Xiong, C., Miller, T. M., Goate, A., Morris, J., Kopan, R., Miller, J. P., Mintun, M. A., Meuser, T., Harris, D., McKeel, D., Miller, T. M. & Mintun, M. A.
9/30/85 → 4/30/20
Project: Research project
Research Output 1992 2019
5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway
Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C-C., Kanekiyo, T. & Bu, G. D., Mar 2 2019, In : International Journal of Molecular Sciences. 20, 6, 1488.Research output: Contribution to journal › Article
Open Access
Serotonin 5-HT3 Receptor Antagonists
Ondansetron
secretions
Apolipoproteins E
liver
ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain
Aikawa, T., Ren, Y., Yamazaki, Y., Tachibana, M., Johnson, M. R., Anderson, C. T., Martens, Y. A., Holm, M. L., Asmann, Y. W., Saito, T., Saido, T. C., Fitzgerald, M. L., Bu, G. & Kanekiyo, T., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 47, p. 23790-23796 7 p.Research output: Contribution to journal › Article
Alzheimer Disease
Amyloid
Brain
Nonsense Codon
Microglia
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II
Zhao, S., Li, Z., Zhang, M., Zhang, L., Zheng, H., Ning, J., Wang, Y., Wang, F., Zhang, X., Gan, H., Wang, Y., Zhang, X., Luo, H., Bu, G. D., Xu, H., Yao, Y. & Zhang, Y. W., Jul 1 2019, In : Experimental and Molecular Medicine. 51, 7, 84.Research output: Contribution to journal › Article
Open Access
Phosphorylation
Brain
Mutation
Electroencephalography
Neurons
4
Citations
(Scopus)
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1
Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.Research output: Contribution to journal › Article
LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
4
Citations
(Scopus)
Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies
Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.Research output: Contribution to journal › Review article
Apolipoproteins E
Alzheimer Disease
Apolipoprotein E4
Alleles
Pathology