Guojun D Bu, PhD

Professor

  • 15413 Citations
  • 71 h-Index
1985 …2020
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Low Density Lipoprotein Receptor-Related Protein-1 Medicine & Life Sciences
LDL Receptors Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Lipoprotein Receptors Medicine & Life Sciences
LDL-Receptor Related Proteins Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Apolipoproteins E Medicine & Life Sciences
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1985 2020

Integrative translational discovery of vascular risk factors in aging and dementia

Bu, G. D., Mangravite, L. & Ertekin-Taner, N.

National Institutes of Health

9/30/158/31/20

Project: Research project

Cerebral Amyloid Angiopathy
Dementia
Alzheimer Disease
Apolipoproteins E
Amyloid Plaques
Apolipoprotein E4
Apolipoproteins E
Dendrites
Lipid Metabolism
Alzheimer Disease

MAYO ALZHEIMERS DISEASE RESEARCH CENTER

Petrucelli, L., Tangalos, E. G., Jack, C. R. J., Dickson, D. W., Boeve, B. F., Younkin, S. G., Kantarci, K. M., Smith, G. E., Rademakers, R. V., Petersen, R. C., Pankratz, V. S., Yen, S. C., Tangalos, E. G., Jack, C. R. J., Dickson, D. W., Vemuri, P. D., Lucas, J. A., Knopman, D. S., Hutton, M. L., Bu, G. D., Edland, S. D., Hutton, M. L., Clifford, J., Kokman, E., Ertekin-Taner, N., Hutton, M. L. & Ertekin-Taner, N.

National Institutes of Health

5/1/994/30/19

Project: Research project

Alzheimer Disease
Research
Dementia
Lewy Body Disease
Brain

ALZHEIMER'S DISEASE RESEARCH CENTER

Bu, G. D., Robins, L. E. E., Miller, T. M., Miller, J. P., Mintun, M. A., Harris, D., Snider, W., Edwards, D., Hale, S., Storandt, M., Schwartz, A., Miller, J. P., Mann Koepke, K., McKeel, D., Goate, A., Morris, J., Edwards, D., Hale, S., Schwartz, A., Merlie, J., Schmidt, D., Botwinick, J., Fagan, A., Denny, A., Willard, M., Toga, A., Musiek, E. S., Fulling, K., Cirrito, J., Robins, L. E. E., Schlesinger, M., Carr, D., O'Malley, K., Fischbach, G., Peck, W., Price, J., Olney, J., Berg, L., Snider, W., Miller, J. P., Mann Koepke, K., Buckner, R., Johnson, E., Holtzman, D., Cairns, N. J., Perrin, R. J., Galvin, J., Xiong, C., Miller, T. M., Goate, A., Morris, J., Kopan, R., Miller, J. P., Mintun, M. A., Meuser, T., Harris, D., McKeel, D., Miller, T. M. & Mintun, M. A.

National Institutes of Health

9/30/854/30/20

Project: Research project

Research Output 1992 2019

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
1 Citation (Scopus)

AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model

Hettinger, J. C., Lee, H., Bu, G. D., Holtzman, D. M. & Cirrito, J. R., May 15 2018, In : Molecular Neurodegeneration. 13, 1, 22.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Amyloid
Alzheimer Disease
Extracellular Fluid
AMPA Receptors
4 Citations (Scopus)

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

Zhong, L., Wang, Z., Wang, D., Wang, Z., Martens, Y. A., Wu, L., Xu, Y., Wang, K., Li, J., Huang, R., Can, D., Xu, H., Bu, G. D. & Chen, X. F., Mar 27 2018, In : Molecular Neurodegeneration. 13, 1, 15.

Research output: Contribution to journalArticle

Myeloid Cells
Amyloid
Alzheimer Disease
Microglia
Cluster Analysis

A novel link between trafficking and Lewy body disorders

Ross, O. A. & Bu, G. D., Jul 1 2018, In : The Lancet Neurology. 17, 7, p. 571-573 3 p.

Research output: Contribution to journalComment/debate

Lewy Bodies
3 Citations (Scopus)

APOE ε2 is associated with increased tau pathology in primary tauopathy

Zhao, N., Liu, C-C., Van Ingelgom, A. J., Linares, C., Kurti, A., Knight, J. A., Heckman, M. G., Diehl, N. N., Shinohara, M., Martens, Y. A., Attrebi, O. N., Petrucelli, L., Fryer, J. D., Wszolek, Z. K., Graff Radford, N. R., Caselli, R. J., Sanchez-Contreras, M. Y., Rademakers, R. V., Murray, M. E., Koga, S. & 3 othersDickson, D. W., Ross, O. A. & Bu, G. D., Dec 1 2018, In : Nature Communications. 9, 1, 4388.

Research output: Contribution to journalArticle

Apolipoprotein E2
Tauopathies
pathology
Pathology
mice