• 17151 Citations
  • 74 Scopus h-Index
1985 …2020
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Fingerprint Dive into the research topics where Guojun D Bu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Low Density Lipoprotein Receptor-Related Protein-1 Medicine & Life Sciences
LDL Receptors Medicine & Life Sciences
Lipoprotein Receptors Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Apolipoproteins E Medicine & Life Sciences
LDL-Receptor Related Proteins Medicine & Life Sciences
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1985 2020

Cerebral Amyloid Angiopathy
Dementia
Alzheimer Disease
Apolipoproteins E
Amyloid Plaques
Apolipoprotein E4
Apolipoproteins E
Dendrites
Lipid Metabolism
Alzheimer Disease

ALZHEIMER'S DISEASE RESEARCH CENTER

Bu, G. D., Robins, L. E. E., Miller, T. M., Miller, J. P., Mintun, M. A., Harris, D., Snider, W., Edwards, D., Hale, S., Storandt, M., Schwartz, A., Miller, J. P., Mann Koepke, K., McKeel, D., Goate, A., Morris, J., Edwards, D., Hale, S., Schwartz, A., Merlie, J., Schmidt, D., Botwinick, J., Fagan, A., Denny, A., Willard, M., Toga, A., Musiek, E. S., Fulling, K., Cirrito, J., Robins, L. E. E., Schlesinger, M., Carr, D., O'Malley, K., Fischbach, G., Peck, W., Price, J., Olney, J., Berg, L., Snider, W., Miller, J. P., Mann Koepke, K., Buckner, R., Johnson, E., Holtzman, D., Cairns, N. J., Perrin, R. J., Galvin, J., Xiong, C., Miller, T. M., Goate, A., Morris, J., Kopan, R., Miller, J. P., Mintun, M. A., Meuser, T., Harris, D., McKeel, D., Miller, T. M. & Mintun, M. A.

National Institutes of Health

9/30/854/30/20

Project: Research project

Research Output 1992 2019

5-HT3 antagonist ondansetron increases apoE secretion by modulating the LXR-ABCA1 pathway

Shinohara, M., Shinohara, M., Zhao, J., Fu, Y., Liu, C-C., Kanekiyo, T. & Bu, G. D., Mar 2 2019, In : International Journal of Molecular Sciences. 20, 6, 1488.

Research output: Contribution to journalArticle

Open Access
Serotonin 5-HT3 Receptor Antagonists
Ondansetron
secretions
Apolipoproteins E
liver

ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain

Aikawa, T., Ren, Y., Yamazaki, Y., Tachibana, M., Johnson, M. R., Anderson, C. T., Martens, Y. A., Holm, M. L., Asmann, Y. W., Saito, T., Saido, T. C., Fitzgerald, M. L., Bu, G. & Kanekiyo, T., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 47, p. 23790-23796 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Amyloid
Brain
Nonsense Codon
Microglia

A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II

Zhao, S., Li, Z., Zhang, M., Zhang, L., Zheng, H., Ning, J., Wang, Y., Wang, F., Zhang, X., Gan, H., Wang, Y., Zhang, X., Luo, H., Bu, G. D., Xu, H., Yao, Y. & Zhang, Y. W., Jul 1 2019, In : Experimental and Molecular Medicine. 51, 7, 84.

Research output: Contribution to journalArticle

Open Access
Phosphorylation
Brain
Mutation
Electroencephalography
Neurons
4 Citations (Scopus)

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
4 Citations (Scopus)

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

Research output: Contribution to journalReview article

Apolipoproteins E
Alzheimer Disease
Apolipoprotein E4
Alleles
Pathology