• 18444 Citations
  • 75 Scopus h-Index
1985 …2020

Research output per year

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Research Output

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Review article
2020

Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome

Qu, W., Wang, Z., Hare, J. M., Bu, G., Mallea, J. M., Pascual, J. M., Caplan, A. I., Kurtzberg, J., Zubair, A. C., Kubrova, E., Engelberg-Cook, E., Nayfeh, T., Shah, V. P., Hill, J. C., Wolf, M. E., Prokop, L. J., Murad, M. H. & Sanfilippo, F. P., 2020, (Accepted/In press) In : Stem Cells Translational Medicine.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations
2019

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

Research output: Contribution to journalReview article

44 Scopus citations
2017

Role of LRP1 in the pathogenesis of Alzheimer's disease: Evidence from clinical and preclinical studies

Shinohara, M., Tachibana, M., Kanekiyo, T. & Bu, G., Jan 1 2017, In : Journal of Lipid Research. 58, 7, p. 1267-1281 15 p.

Research output: Contribution to journalReview article

41 Scopus citations
2016

Implications of GABAergic neurotransmission in Alzheimer's disease

Li, Y., Sun, H., Chen, Z., Xu, H., Bu, G. & Zheng, H., 2016, In : Frontiers in Aging Neuroscience. 8, FEB, 31.

Research output: Contribution to journalReview article

68 Scopus citations

The role of APOE in cerebrovascular dysfunction

Tai, L. M., Thomas, R., Marottoli, F. M., Koster, K. P., Kanekiyo, T., Morris, A. W. J. & Bu, G., May 1 2016, In : Acta neuropathologica. 131, 5, p. 709-723 15 p.

Research output: Contribution to journalReview article

59 Scopus citations

TREMs in Alzheimer's disease: Genetic and clinical investigations

Cheng, J., Guo, X. F., Zhang, T., Zhong, L., Bu, G. D. & Chen, X. F., Dec 1 2016, In : Clinica Chimica Acta. 463, p. 88-95 8 p.

Research output: Contribution to journalReview article

11 Scopus citations
2015

TREM2 in CNS homeostasis and neurodegenerative disease

Painter, M. M., Atagi, Y., Liu, C. C., Rademakers, R., Xu, H., Fryer, J. D. & Bu, G., Sep 4 2015, In : Molecular neurodegeneration. 10, 1, 43.

Research output: Contribution to journalReview article

51 Scopus citations
2014

ApoE and Aβ in Alzheimer's disease: Accidental encounters or partners?

Kanekiyo, T., Xu, H. & Bu, G., Feb 19 2014, In : Neuron. 81, 4, p. 740-754 15 p.

Research output: Contribution to journalReview article

255 Scopus citations

Dysregulation of protein trafficking in neurodegeneration

Wang, X., Huang, T., Bu, G. D. & Xu, H., 2014, In : Molecular Neurodegeneration. 9, p. 31 1 p.

Research output: Contribution to journalReview article

58 Scopus citations

M1 muscarinic acetylcholine receptor in Alzheimer's disease

Jiang, S., Li, Y., Zhang, C., Zhao, Y., Bu, G., Xu, H. & Zhang, Y. W., Apr 2014, In : Neuroscience Bulletin. 30, 2, p. 295-307 13 p.

Research output: Contribution to journalReview article

70 Scopus citations

Soluble apoE/Aβ complex: Mechanism and therapeutic target for APOE4-induced AD risk

Tai, L. M., Mehra, S., Shete, V., Estus, S., Rebeck, G. W., Bu, G. & Ladu, M. J., Jan 4 2014, In : Molecular neurodegeneration. 9, 1, 2.

Research output: Contribution to journalReview article

70 Scopus citations
103 Scopus citations

Trafficking regulation of proteins in Alzheimer's disease

Jiang, S., Li, Y., Zhang, X., Bu, G., Xu, H. & Zhang, Y. W., Jan 11 2014, In : Molecular neurodegeneration. 9, 1, 6.

Research output: Contribution to journalReview article

87 Scopus citations
2013

Apolipoprotein e and Alzheimer disease: Risk, mechanisms and therapy

Liu, C. C., Kanekiyo, T., Xu, H. & Bu, G., Feb 1 2013, In : Nature Reviews Neurology. 9, 2, p. 106-118 13 p.

Research output: Contribution to journalReview article

1153 Scopus citations

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease

Wolf, A. B., Valla, J., Bu, G., Kim, J., Ladu, M. J., Reiman, E. M. & Caselli, R. J., Nov 25 2013, In : Alzheimer's Research and Therapy. 5, 5, 38.

Research output: Contribution to journalReview article

36 Scopus citations

Transcriptional regulation and its misregulation in Alzheimer's disease

Chen, X. F., Zhang, Y. W., Xu, H. & Bu, G., Oct 29 2013, In : Molecular brain. 6, 1, 44.

Research output: Contribution to journalReview article

23 Scopus citations
2009

Apolipoprotein e and its receptors in Alzheimer's disease: Pathways, pathogenesis and therapy

Bu, G., May 1 2009, In : Nature Reviews Neuroscience. 10, 5, p. 333-344 12 p.

Research output: Contribution to journalReview article

694 Scopus citations

Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease

Marzolo, M. P. & Bu, G., Apr 2009, In : Seminars in Cell and Developmental Biology. 20, 2, p. 191-200 10 p.

Research output: Contribution to journalReview article

75 Scopus citations

LRP1 and cerebral amyloid angiopathy

Kanekiyo, T. & Bu, G., Jun 19 2009, In : Future Neurology. 4, 1, p. 55-65 11 p.

Research output: Contribution to journalReview article

2 Scopus citations
2006

The generation and function of soluble apoE receptors in the CNS

Rebeck, G. W., LaDu, M. J., Estus, S., Bu, G. & Weeber, E. J., Dec 1 2006, In : Molecular neurodegeneration. 1, 1, 15.

Research output: Contribution to journalReview article

40 Scopus citations

Zoom in on neurodegeneration

Guojun, B., Huaxi, X. & Golde, T. E., Dec 1 2006, In : Molecular neurodegeneration. 1, 1, 1.

Research output: Contribution to journalReview article

1 Scopus citations
2005

LRP5/6 in Wnt signaling and tumorigenesis

Li, Y. & Bu, G., Oct 1 2005, In : Future Oncology. 1, 5, p. 673-681 9 p.

Research output: Contribution to journalReview article

23 Scopus citations

LRP and Alzheimer's disease

Zerbinatti, C. V. & Bu, G., Jan 1 2005, In : Reviews in the Neurosciences. 16, 2, p. 123-135 13 p.

Research output: Contribution to journalReview article

59 Scopus citations
2001

Low-density lipoprotein receptor family: Endocytosis and signal transduction

Li, Y., Cam, J. & Bu, G., Jan 1 2001, In : Molecular Neurobiology. 23, 1, p. 53-67 15 p.

Research output: Contribution to journalReview article

97 Scopus citations
100 Scopus citations
2000

Role of RAP in the biogenesis of lipoprotein receptors

Bu, G. & Marzolo, M. P., Dec 1 2000, In : Trends in cardiovascular medicine. 10, 4, p. 148-155 8 p.

Research output: Contribution to journalReview article

54 Scopus citations
1998

RAP a novel type of ER chaperone

Bu, G. & Schwartz, A. L., Dec 1 1998, In : Trends in Cell Biology. 8, 7, p. 272-276 5 p.

Research output: Contribution to journalReview article

87 Scopus citations

Receptor-associated protein: A specialized chaperone and antagonist for members of the LDL receptor gene family

Bu, G., Apr 21 1998, In : Current opinion in lipidology. 9, 2, p. 149-155 7 p.

Research output: Contribution to journalReview article

64 Scopus citations
1994

Cellular receptors for the plasminogen activators

Bu, G., Warshawsky, I. & Schwartz, A. L., Jun 15 1994, In : Blood. 83, 12, p. 3427-3436 10 p.

Research output: Contribution to journalReview article

74 Scopus citations