Projects per year
Fingerprint Dive into the research topics where Evette S Radisky is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Trypsin
Medicine & Life Sciences
Matrix Metalloproteinases
Medicine & Life Sciences
Protease Inhibitors
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Breast Neoplasms
Medicine & Life Sciences
Amyloid beta-Protein Precursor
Medicine & Life Sciences
Proteolysis
Chemical Compounds
Aprotinin
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2001 2018
Serine Proteases
Subtilisin
Enzymes
Catalysis
Substrates
Targeting the IL-6 - SPINK1 regulatory axis in ovarian clear cell carcinoma
Project: Research project
PRINCIPAL NIH RESEARCH RESOURCE X RAY BEAMLINE AT NSLS: WIGGLER BEAMLINE X25
Radisky, E. S. & Radisky, E. S.
Project: Research project
Targeting MMP-9 for breast cancer therapy (R21 CA205471 Resubmission)
7/1/16 → 6/30/18
Project: Research project
Matrix Metalloproteinase 9
Breast Neoplasms
Matrix Metalloproteinase Inhibitors
Therapeutics
Matrix Metalloproteinases
Defining SPINK1 as a tumor driver and therapeutic target in ovarian cancer
7/1/13 → 6/30/15
Project: Research project
Ovarian Neoplasms
Epidermal Growth Factor Receptor
Neoplasms
Therapeutics
X Ray Crystallography
Research Output 1990 2019
Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition
Raeeszadeh-Sarmazdeh, M., Greene, K. A., Sankaran, B., Downey, G. P., Radisky, D. C. & Radisky, E. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 24, p. 9476-9488 13 p.Research output: Contribution to journal › Article
Tissue Inhibitor of Metalloproteinase-1
Tissue Inhibitor of Metalloproteinases
Metalloproteases
Matrix Metalloproteinases
Matrix Metalloproteinase 3
1
Citation
(Scopus)
Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin
Cohen, I., Coban, M., Shahar, A., Sankaran, B., Hockla, A., Lacham, S., Caulfield, T., Radisky, E. S. & Papo, N., Jan 1 2019, In : Journal of Biological Chemistry. 294, 13, p. 5105-5120 16 p.Research output: Contribution to journal › Article
Proteolysis
Serine Proteinase Inhibitors
Human Engineering
Disulfides
Peptide Hydrolases
Novel pathogenic PRSS1 variant p.Glu190Lys in a case of chronic pancreatitis
Jancsó, Z., Oracz, G., Kujko, A. A., Kolodziejczyk, E., Radisky, E. S., Rygiel, A. M. & Sahin-Tóth, M., Jan 1 2019, In : Frontiers in Genetics. 10, FEB, 46.Research output: Contribution to journal › Article
Open Access
Trypsinogen
Chronic Pancreatitis
trypsinogen activation peptide
Mutation
Enzyme Precursors
PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma
Ma, H., Hockla, A., Mehner, C., Coban, M., Papo, N., Radisky, D. C. & Radisky, E. S., Dec 1 2019, In : Scientific reports. 9, 1, 1844.Research output: Contribution to journal › Article
Open Access
Kallikreins
Peptide Hydrolases
Growth
Neoplasms
Serine Proteases
2
Citations
(Scopus)
A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering
Sananes, A., Cohen, I., Shahar, A., Hockla, A., De Vita, E., Miller, A. K., Radisky, E. S. & Papo, N., Jan 1 2018, In : Journal of Biological Chemistry. 293, 33, p. 12663-12680 18 p.Research output: Contribution to journal › Article
Proteolysis
Kallikreins
Peptide Hydrolases
Neoplasms
Protease Inhibitors