• 2047 Citations
  • 25 Scopus h-Index
1990 …2019
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Fingerprint Dive into the research topics where Evette S Radisky is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Trypsin Medicine & Life Sciences
Matrix Metalloproteinases Medicine & Life Sciences
Protease Inhibitors Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Proteolysis Chemical Compounds
Aprotinin Medicine & Life Sciences

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Projects 2001 2018

Serine Proteases
Subtilisin
Enzymes
Catalysis
Substrates
Matrix Metalloproteinase 9
Breast Neoplasms
Matrix Metalloproteinase Inhibitors
Therapeutics
Matrix Metalloproteinases
Ovarian Neoplasms
Epidermal Growth Factor Receptor
Neoplasms
Therapeutics
X Ray Crystallography

Research Output 1990 2019

  • 2047 Citations
  • 25 Scopus h-Index
  • 59 Article
  • 1 Chapter
  • 1 Review article

Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition

Raeeszadeh-Sarmazdeh, M., Greene, K. A., Sankaran, B., Downey, G. P., Radisky, D. C. & Radisky, E. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 24, p. 9476-9488 13 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-1
Tissue Inhibitor of Metalloproteinases
Metalloproteases
Matrix Metalloproteinases
Matrix Metalloproteinase 3
1 Citation (Scopus)

Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin

Cohen, I., Coban, M., Shahar, A., Sankaran, B., Hockla, A., Lacham, S., Caulfield, T., Radisky, E. S. & Papo, N., Jan 1 2019, In : Journal of Biological Chemistry. 294, 13, p. 5105-5120 16 p.

Research output: Contribution to journalArticle

Proteolysis
Serine Proteinase Inhibitors
Human Engineering
Disulfides
Peptide Hydrolases

Novel pathogenic PRSS1 variant p.Glu190Lys in a case of chronic pancreatitis

Jancsó, Z., Oracz, G., Kujko, A. A., Kolodziejczyk, E., Radisky, E. S., Rygiel, A. M. & Sahin-Tóth, M., Jan 1 2019, In : Frontiers in Genetics. 10, FEB, 46.

Research output: Contribution to journalArticle

Open Access
Trypsinogen
Chronic Pancreatitis
trypsinogen activation peptide
Mutation
Enzyme Precursors

PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma

Ma, H., Hockla, A., Mehner, C., Coban, M., Papo, N., Radisky, D. C. & Radisky, E. S., Dec 1 2019, In : Scientific reports. 9, 1, 1844.

Research output: Contribution to journalArticle

Open Access
Kallikreins
Peptide Hydrolases
Growth
Neoplasms
Serine Proteases
2 Citations (Scopus)

A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering

Sananes, A., Cohen, I., Shahar, A., Hockla, A., De Vita, E., Miller, A. K., Radisky, E. S. & Papo, N., Jan 1 2018, In : Journal of Biological Chemistry. 293, 33, p. 12663-12680 18 p.

Research output: Contribution to journalArticle

Proteolysis
Kallikreins
Peptide Hydrolases
Neoplasms
Protease Inhibitors