Clifford R Jr. Jack, MD

  • 83433 Citations
  • 139 Scopus h-Index
1984 …2020

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Research Output

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Review article
2019

A brief history of "Alzheimer disease": Multiple meanings separated by a common name

Knopman, D. S., Petersen, R. C. & Jack, C. R. J., May 28 2019, In : Neurology. 92, 22, p. 1053-1059 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

Limbic-predominant age-related TDP-43 encephalopathy (LATE): Consensus working group report

Nelson, P. T., Dickson, D. W., Trojanowski, J. Q., Jack, C. R., Boyle, P. A., Arfanakis, K., Rademakers, R., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, I. T. S., Chui, H. C., Fardo, D. W., Flanagan, M. E., Halliday, G., Hokkanen, S. R. K., Hunter, S., Jicha, G. A., Katsumata, Y., Kawas, C. H. & 15 others, Keene, C. D., Kovacs, G. G., Kukull, W. A., Levey, A. I., Makkinejad, N., Montine, T. J., Murayama, S., Murray, M. E., Nag, S., Rissman, R. A., Seeley, W. W., Sperling, R. A., White, C. L., Yu, L. & Schneider, J. A., Jun 1 2019, In : Brain. 142, 6, p. 1503-1527 25 p.

Research output: Contribution to journalReview article

Open Access
87 Scopus citations

Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative

Alzheimer's Disease Neuroimaging Initiative, Jan 2019, In : Alzheimer's and Dementia. 15, 1, p. 106-152 47 p.

Research output: Contribution to journalReview article

30 Scopus citations
2018

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

on Behalf of the Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut, May 19 2018, In : World Journal of Biological Psychiatry. 19, 4, p. 244-328 85 p.

Research output: Contribution to journalReview article

70 Scopus citations

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

Contributors, Apr 2018, In : Alzheimer's and Dementia. 14, 4, p. 535-562 28 p.

Research output: Contribution to journalReview article

923 Scopus citations

Quantitative magnetic resonance imaging phantoms: A review and the need for a system phantom

Keenan, K. E., Ainslie, M., Barker, A. J., Boss, M. A., Cecil, K. M., Charles, C., Chenevert, T. L., Clarke, L., Evelhoch, J. L., Finn, P., Gembris, D., Gunter, J. L., Hill, D. L. G., Jack, C. R., Jackson, E. F., Liu, G., Russek, S. E., Sharma, S. D., Steckner, M., Stupic, K. F. & 3 others, Trzasko, J. D., Yuan, C. & Zheng, J., Jan 2018, In : Magnetic Resonance in Medicine. 79, 1, p. 48-61 14 p.

Research output: Contribution to journalReview article

31 Scopus citations
2017

Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework

Chiotis, K., Saint-Aubert, L., Boccardi, M., Gietl, A., Picco, A., Varrone, A., Garibotto, V., Herholz, K., Nobili, F., Nordberg, A., Frisoni, G. B., Winblad, B. & Jack, C. R. J., Apr 1 2017, In : Neurobiology of Aging. 52, p. 214-227 14 p.

Research output: Contribution to journalReview article

29 Scopus citations

Clinical validity of medial temporal atrophy as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework

ten Kate, M., Barkhof, F., Boccardi, M., Visser, P. J., Jack, C. R. J., Lovblad, K. O., Frisoni, G. B. & Scheltens, P., Apr 1 2017, In : Neurobiology of Aging. 52, p. 167-182 16 p.

Research output: Contribution to journalReview article

25 Scopus citations

On the path to 2025: Understanding the Alzheimer's disease continuum

Aisen, P. S., Cummings, J., Jack, C. R., Morris, J. C., Sperling, R., Frölich, L., Jones, R. W., Dowsett, S. A., Matthews, B. R., Raskin, J., Scheltens, P. & Dubois, B., Aug 9 2017, In : Alzheimer's Research and Therapy. 9, 1, 60.

Research output: Contribution to journalReview article

71 Scopus citations

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

Alzheimer's Disease Neuroimaging Initiative, Apr 1 2017, In : Alzheimer's and Dementia. 13, 4, p. e1-e85

Research output: Contribution to journalReview article

78 Scopus citations

Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers

Frisoni, G. B., Boccardi, M., Barkhof, F., Blennow, K., Cappa, S., Chiotis, K., Démonet, J. F., Garibotto, V., Giannakopoulos, P., Gietl, A., Hansson, O., Herholz, K., Jack, C. R., Nobili, F., Nordberg, A., Snyder, H. M., Ten Kate, M., Varrone, A., Albanese, E., Becker, S. & 28 others, Bossuyt, P., Carrillo, M. C., Cerami, C., Dubois, B., Gallo, V., Giacobini, E., Gold, G., Hurst, S., Lönneborg, A., Lovblad, K. O., Mattsson, N., Molinuevo, J. L., Monsch, A. U., Mosimann, U., Padovani, A., Picco, A., Porteri, C., Ratib, O., Saint-Aubert, L., Scerri, C., Scheltens, P., Schott, J. M., Sonni, I., Teipel, S., Vineis, P., Visser, P. J., Yasui, Y. & Winblad, B., Aug 2017, In : The Lancet Neurology. 16, 8, p. 661-676 16 p.

Research output: Contribution to journalReview article

154 Scopus citations

The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : Alzheimer's and Dementia. 13, 5, p. 561-571 11 p.

Research output: Contribution to journalReview article

45 Scopus citations

The biomarker-based diagnosis of Alzheimer's disease. 2—lessons from oncology

Geneva Task Force for the Roadmap of Alzheimer's Biomarkers, Apr 1 2017, In : Neurobiology of Aging. 52, p. 141-152 12 p.

Research output: Contribution to journalReview article

21 Scopus citations
2016

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

Jack, C. R., Bennett, D. A., Blennow, K., Carrillo, M. C., Feldman, H. H., Frisoni, G. B., Hampel, H., Jagust, W. J., Johnson, K. A., Knopman, D. S., Petersen, R. C., Scheltens, P., Sperling, R. A. & Dubois, B., Aug 2 2016, In : Neurology. 87, 5, p. 539-547 9 p.

Research output: Contribution to journalReview article

320 Scopus citations
5 Scopus citations

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

Proceedings of the Meeting of the International Working Group (IWG) and the American Alzheimer's Association on "The Preclinical State of AD"; July 23, 2015; Washington DC, USA, Mar 1 2016, In : Alzheimer's and Dementia. 12, 3, p. 292-323 32 p.

Research output: Contribution to journalReview article

445 Scopus citations

Suspected non-Alzheimer disease pathophysiology-concept and controversy

Jack, C. R., Knopman, D. S., Chételat, G., Dickson, D., Fagan, A. M., Frisoni, G. B., Jagust, W., Mormino, E. C., Petersen, R. C., Sperling, R. A., Van Der Flier, W. M., Villemagne, V. L., Visser, P. J. & Vos, S. J. B., Feb 1 2016, In : Nature Reviews Neurology. 12, 2, p. 117-124 8 p.

Research output: Contribution to journalReview article

135 Scopus citations
2015

Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014

Weiner, M. W., Veitch, D. P., Aisen, P. S., Beckett, L. A., Cairns, N. J., Cedarbaum, J., Donohue, M. C., Green, R. C., Harvey, D., Jack, C. R., Jagust, W., Morris, J. C., Petersen, R. C., Saykin, A. J., Shaw, L., Thompson, P. M., Toga, A. W. & Trojanowski, J. Q., Jul 1 2015, In : Alzheimer's and Dementia. 11, 7, p. 865-884 20 p.

Research output: Contribution to journalReview article

95 Scopus citations
2014

Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementias

Murray, M. E., Kouri, N., Lin, W. L., Jack, C. R., Dickson, D. W. & Vemuri, P., Jan 2 2014, In : Alzheimer's Research and Therapy. 6, 1, 1.

Research output: Contribution to journalReview article

58 Scopus citations

Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition

Alzheimer's Disease Neuroimaging Initiative, Jan 27 2014, In : Acta Neuropathologica Communications. 2, 1, 26.

Research output: Contribution to journalReview article

59 Scopus citations
2013

Biomarker modeling of alzheimer's disease

Jack, C. R. & Holtzman, D. M., Dec 18 2013, In : Neuron. 80, 6, p. 1347-1358 12 p.

Research output: Contribution to journalReview article

414 Scopus citations

Cerebral amyloid PET imaging in Alzheimer's disease

Jack, C. R., Barrio, J. R. & Kepe, V., Nov 1 2013, In : Acta neuropathologica. 126, 5, p. 643-657 15 p.

Research output: Contribution to journalReview article

61 Scopus citations

Imaging markers for Alzheimer disease: Which vs how

Frisoni, G. B., Bocchetta, M., Chételat, G., Rabinovici, G. D., De Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E., Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R., Jagust, W. J., Johnson, K. A., Rowe, C. C., Sperling, R. A. & 5 others, Thies, W., Wahlund, L. O., Weiner, M. W., Pasqualetti, P. & DeCarli, C., Jul 30 2013, In : Neurology. 81, 5, p. 487-500 14 p.

Research output: Contribution to journalReview article

148 Scopus citations

The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

Weiner, M. W., Veitch, D. P., Aisen, P. S., Beckett, L. A., Cairns, N. J., Green, R. C., Harvey, D., Jack, C. R., Jagust, W., Liu, E., Morris, J. C., Petersen, R. C., Saykin, A. J., Schmidt, M. E., Shaw, L., Shen, L., Siuciak, J. A., Soares, H., Toga, A. W. & Trojanowski, J. Q., Sep 1 2013, In : Alzheimer's and Dementia. 9, 5, p. e111-e194

Research output: Contribution to journalReview article

238 Scopus citations
2012

Alzheimer disease: New concepts on its neurobiology and the clinical role imaging will play

Jack, C. R., Jun 22 2012, In : Radiology. 263, 2, p. 344-361 18 p.

Research output: Contribution to journalReview article

136 Scopus citations

Diagnostic neuroimaging across diseases

Klöppel, S., Abdulkadir, A., Jack, C. R., Koutsouleris, N., Mourão-Miranda, J. & Vemuri, P., Jun 1 2012, In : NeuroImage. 61, 2, p. 457-463 7 p.

Research output: Contribution to journalReview article

176 Scopus citations

Modifiable factors that alter the size of the hippocampus with ageing

Fotuhi, M., Do, D. & Jack, C., Apr 1 2012, In : Nature Reviews Neurology. 8, 4, p. 189-202 14 p.

Research output: Contribution to journalReview article

174 Scopus citations

Resting state functional MRI in Alzheimer's disease

Vemuri, P., Jones, D. T. & Jack, C. R., Jan 1 2012, In : Alzheimer's Research and Therapy. 4, 1, 2.

Research output: Contribution to journalReview article

59 Scopus citations
2011

Imaging the Alzheimer Brain

Ashford, J. W., Salehi, A., Furst, A., Bayley, P., Frisoni, G. B., Jack, C. R., Sabri, O., Adamson, M. M., Coburn, K. L., Olichney, J., Schuff, N., Spielman, D., Edland, S. D., Black, S., Rosen, A., Kennedy, D., Weiner, M. & Perry, G., 2011, In : Journal of Alzheimer's Disease. 26, SUPPL. 3, p. 1-27 27 p.

Research output: Contribution to journalReview article

18 Scopus citations

Magnetic resonance imaging of amyloid plaques in transgenic mouse models of alzheimer's disease

Chamberlain, R., Wengenack, T. M., Poduslo, J. F., Garwood, M. & Jack, C. R., Jun 1 2011, In : Current Medical Imaging Reviews. 7, 1, p. 3-7 5 p.

Research output: Contribution to journalReview article

17 Scopus citations
2010

Role of structural MRI in Alzheimer's disease

Vemuri, P. & Jack, C. R., Sep 10 2010, In : Alzheimer's Research and Therapy. 2, 4, 23.

Research output: Contribution to journalReview article

52 Scopus citations

The clinical use of structural MRI in Alzheimer disease

Frisoni, G. B., Fox, N. C., Jack, C. R., Scheltens, P. & Thompson, P. M., Feb 1 2010, In : Nature Reviews Neurology. 6, 2, p. 67-77 11 p.

Research output: Contribution to journalReview article

876 Scopus citations

Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects

Trojanowski, J. Q., Vandeerstichele, H., Korecka, M., Clark, C. M., Aisen, P. S., Petersen, R. C., Blennow, K., Soares, H., Simon, A., Lewczuk, P., Dean, R., Siemers, E., Potter, W. Z., Weiner, M. W., Jack, C. R., Jagust, W., Toga, A. W., Lee, V. M. Y. & Shaw, L. M., May 1 2010, In : Alzheimer's and Dementia. 6, 3, p. 230-238 9 p.

Research output: Contribution to journalReview article

199 Scopus citations
2009

Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder

Van Boven, R. W., Harrington, G. S., Hackney, D. B., Ebel, A., Gauger, G., Bremner, J. D., D'Esposito, M., Detre, J. A., Haacke, E. M., Jack, C. R., Jagust, W. J., Le Bihan, D., Mathis, C. A., Mueller, S., Mukherjee, P., Schuff, N., Chen, A. & Weiner, M. W., Jan 1 2009, In : Journal of Rehabilitation Research and Development. 46, 6, p. 717-756 40 p.

Research output: Contribution to journalReview article

75 Scopus citations

Mild cognitive impairment: Ten years later

Petersen, R. C., Roberts, R. O., Knopman, D. S., Boeve, B. F., Geda, Y. E., Ivnik, R. J., Smith, G. E. & Jack, C. R., Dec 1 2009, In : Archives of neurology. 66, 12, p. 1447-1455 9 p.

Research output: Contribution to journalReview article

791 Scopus citations
2008

Magnetic resonance imaging research in aging and dementia at the Mayo Clinic

Jack, C. R., Jul 1 2008, In : Alzheimer disease and associated disorders. 22, 3, p. 204-208 5 p.

Research output: Contribution to journalReview article

MR Microimaging of amyloid plaques in Alzheimer's disease transgenic mice

Wengenack, T. M., Jack, C. R., Garwood, M. & Poduslo, J. F., Mar 1 2008, In : European Journal of Nuclear Medicine and Molecular Imaging. 35, SUPPL. 1, p. S82-S88

Research output: Contribution to journalReview article

33 Scopus citations

The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods

Jack, C. R., Bernstein, M. A., Fox, N. C., Thompson, P., Alexander, G., Harvey, D., Borowski, B., Britson, P. J., Whitwell, J. L., Ward, C., Dale, A. M., Felmlee, J. P., Gunter, J. L., Hill, D. L. G., Killiany, R., Schuff, N., Fox-Bosetti, S., Lin, C., Studholme, C., DeCarli, C. S. & 15 others, Krueger, G., Ward, H. A., Metzger, G. J., Scott, K. T., Mallozzi, R., Blezek, D., Levy, J., Debbins, J. P., Fleisher, A. S., Albert, M., Green, R., Bartzokis, G., Glover, G., Mugler, J. & Weiner, M. W., Apr 1 2008, In : Journal of Magnetic Resonance Imaging. 27, 4, p. 685-691 7 p.

Research output: Contribution to journalReview article

1335 Scopus citations
2007

Magnetic resonance imaging of Alzheimer's pathology in the brains of living transgenic mice: A new tool in Alzheimer's disease research

Jack, C. R., Marjanska, M., Wengenack, T. M., Reyes, D. A., Curran, G. L., Lin, J., Preboske, G. M., Poduslo, J. F. & Garwood, M., Feb 1 2007, In : Neuroscientist. 13, 1, p. 38-48 11 p.

Research output: Contribution to journalReview article

60 Scopus citations

Neuroimaging in dementia

Whitwell, J. L. & Jack, C. R., Apr 1 2007, In : CONTINUUM Lifelong Learning in Neurology. 13, 2, p. 180-203 24 p.

Research output: Contribution to journalReview article

2 Scopus citations

Neuroimaging in Dementia

Whitwell, J. L. & Jack, C. R., Jan 1 2007, In : PET Clinics. 2, 1, p. 15-24 10 p.

Research output: Contribution to journalReview article

1 Scopus citations

Neuroimaging in Dementia

Whitwell, J. L. & Jack, C. R., Aug 1 2007, In : Neurologic clinics. 25, 3, p. 843-857 15 p.

Research output: Contribution to journalReview article

18 Scopus citations
2005

The Alzheimer's disease neuroimaging initiative

Mueller, S. G., Weiner, M. W., Thal, L. J., Petersen, R. C., Jack, C., Jagust, W., Trojanowski, J. Q., Toga, A. W. & Beckett, L., Nov 1 2005, In : Neuroimaging Clinics of North America. 15, 4, p. 869-877 9 p.

Research output: Contribution to journalReview article

494 Scopus citations

Ways toward an early diagnosis in Alzheimer's disease: The Alzheimer's Disease Neuroimaging Initiative (ADNI)

Mueller, S. G., Weiner, M. W., Thal, L. J., Petersen, R. C., Jack, C. R., Jagust, W., Trojanowski, J. Q., Toga, A. W. & Beckett, L., Jul 1 2005, In : Alzheimer's and Dementia. 1, 1, p. 55-66 12 p.

Research output: Contribution to journalReview article

554 Scopus citations
2003

Neuroimaging in Alzheimer disease: An evidence-based review

Kantarci, K. & Jack, C. R., May 2003, In : Neuroimaging Clinics of North America. 13, 2, p. 197-209 13 p.

Research output: Contribution to journalReview article

154 Scopus citations
1999

Comparative study of 99mTc-ECD and 99mTc-HMPAO for peri-ictal SPECT: Qualitative and quantitative analysis

O'Brien, T. J., Brinkmann, B. H., Mullan, B. P., So, E. L., Hauser, M. F., O'Connor, M. K., Hung, J. & Jack, C. R., Mar 1999, In : Journal of Neurology Neurosurgery and Psychiatry. 66, 3, p. 331-339 9 p.

Research output: Contribution to journalReview article

Open Access
44 Scopus citations
1997

Volumetric magnetic resonance imaging: Clinical applications and contributions to the understanding of temporal lobe epilepsy

Watson, C., Jack, C. R. & Cendes, F., Dec 1997, In : Archives of neurology. 54, 12, p. 1521-1531 11 p.

Research output: Contribution to journalReview article

178 Scopus citations
1996

Use of functional magnetic resonance imaging

Lee, C. C., Jack, J. & Riederer, S. J., Nov 13 1996, In : Neurosurgery clinics of North America. 7, 4, p. 665-683+viii

Research output: Contribution to journalReview article

6 Scopus citations
1995

Magnetic resonance imaging - Neuroimaging and anatomy

Jack, C. R., Jan 1 1995, In : Neuroimaging Clinics of North America. 5, 4, p. 597-622 26 p.

Research output: Contribution to journalReview article

34 Scopus citations
1988

The past, present, and future of extracranial to intracranial bypass surgery.

Sundt, T. M., Fode, N. C. & Jack, C. R., Jan 1 1988, In : Clinical neurosurgery. 34, p. 134-153 20 p.

Research output: Contribution to journalReview article

19 Scopus citations