• 13161 Citations
  • 54 Scopus h-Index
20052020
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Research Output 2005 2020

2017

Reply: High-Output Heart Failure: With or Without Obesity

Reddy, Y. N. V. & Borlaug, B. A., Jan 3 2017, In : Journal of the American College of Cardiology. 69, 1, p. 113-114 2 p.

Research output: Contribution to journalLetter

Heart Failure
Obesity

Reply: Heart Failure With Preserved Ejection Fraction: A Late Stage of Hypertensive Heart Disease

Reddy, Y. N. V. & Borlaug, B. A., Nov 7 2017, In : Journal of the American College of Cardiology. 70, 19, p. 2458-2459 2 p.

Research output: Contribution to journalLetter

Heart Diseases
Heart Failure

Reply to 'Cardiac remodeling after reduction of high-flow arteriovenous fistulas in end-stage renal disease: Methodological issues'

Wohlfahrt, P., Rokosny, S., Melenovsky, V., Borlaug, B. A., Pecenkova, V. & Balaz, P., Apr 1 2017, In : Hypertension Research. 40, 4, p. 411 1 p.

Research output: Contribution to journalLetter

Arteriovenous Fistula
Chronic Kidney Failure
11 Citations (Scopus)

Resting and exercise haemodynamics in relation to six-minute walk test in patients with heart failure and preserved ejection fraction

Wolsk, E., Kaye, D., Borlaug, B. A., Burkhoff, D., Kitzman, D. W., Komtebedde, J., Lam, C. S. P., Ponikowski, P., Shah, S. J. & Gustafsson, F., 2017, (Accepted/In press) In : European Journal of Heart Failure.

Research output: Contribution to journalArticle

Heart Failure
Hemodynamics
Exercise
Pulmonary Wedge Pressure
Confidence Intervals
113 Citations (Scopus)

Role of Diastolic Stress Testing in the Evaluation for Heart Failure with Preserved Ejection Fraction: A Simultaneous Invasive-Echocardiographic Study

Obokata, M., Kane, G. M., Reddy, Y. N. V., Olson, T. P., Melenovsky, V. & Borlaug, B. A., Feb 28 2017, In : Circulation. 135, 9, p. 825-838 14 p.

Research output: Contribution to journalArticle

Heart Failure
Pulmonary Wedge Pressure
Brain Natriuretic Peptide
Echocardiography
Guidelines
11 Citations (Scopus)

SCAI/HFSA clinical expert consensus document on the use of invasive hemodynamics for the diagnosis and management of cardiovascular disease

Sorajja, P., Borlaug, B. A., Dimas, V. V., Fang, J. C., Forfia, P. R., Givertz, M. M., Kapur, N. K., Kern, M. J. & Naidu, S. S., Jun 1 2017, In : Catheterization and Cardiovascular Interventions. 89, 7, p. E233-E247

Research output: Contribution to journalEditorial

Cardiovascular Diseases
Hemodynamics

Sildenafil, unbridled optimism, and heart failure with preserved ejection fraction

Reddy, Y. N. V. & Borlaug, B. A., Jan 1 2017, In : European Journal of Heart Failure. 19, 1, p. 126-128 3 p.

Research output: Contribution to journalEditorial

Heart Failure
Sildenafil Citrate
Optimism
2 Citations (Scopus)

Some Laws Were not Made to be Broken. When Frank-Starling Reserve Is Lost in Heart Failure*

Borlaug, B. A. & Reddy, Y. N. V., 2017, (Accepted/In press) In : JACC: Cardiovascular Imaging.

Research output: Contribution to journalArticle

Starlings
Heart Failure
19 Citations (Scopus)

Suppression of tumorigenicity 2 in heart failure with preserved ejection fraction

Abou Ezzeddine, O., McKie, P., Dunlay, S. M., Stevens, S. R., Felker, G. M., Borlaug, B. A., Chen, H. H., Tracy, R. P., Braunwald, E. & Redfield, M. M., 2017, In : Journal of the American Heart Association. 6, 2, e004382.

Research output: Contribution to journalArticle

Heart Failure
Biomarkers
Inflammation
Ventricular Dysfunction
Ventricular Pressure
2016
97 Citations (Scopus)
Pulmonary Artery
Heart Failure
Exercise
Cardiac Output
Mechanics
3 Citations (Scopus)

Beating Heart Validation of Safety and Efficacy of a Percutaneous Pericardiotomy Tool

Killu, A. M., Naksuk, N., Desimone, C. V., Gaba, P., Suddendorf, S., Powers, J., Ladewig, D. J., Lerman, L. O., Borlaug, B. A. & Asirvatham, S. J., 2016, (Accepted/In press) In : Journal of Cardiovascular Electrophysiology.

Research output: Contribution to journalArticle

Pericardiectomy
Safety
Phrenic Nerve
Pericardium
Equipment and Supplies
3 Citations (Scopus)

Cardiac aging and the fountain of youth

Borlaug, B. A., Jun 1 2016, In : European Journal of Heart Failure. 18, 6, p. 611-612 2 p.

Research output: Contribution to journalArticle

Nitrites
Nitrates
Nitric Oxide
Heart Failure
8 Citations (Scopus)

Cardiac remodeling after reduction of high-flow arteriovenous fistulas in end-stage renal disease

Wohlfahrt, P., Rokosny, S., Melenovsky, V., Borlaug, B. A., Pecenkova, V. & Balaz, P., Sep 1 2016, In : Hypertension Research. 39, 9, p. 654-659 6 p.

Research output: Contribution to journalArticle

Arteriovenous Fistula
Chronic Kidney Failure
Vascular Resistance
Heart Failure
Cardiac Output

Cell Therapy for Heart Failure With Preserved Ejection Fraction

Borlaug, B. A. & Reddy, Y. N. V., Feb 1 2016, In : JACC: Basic to Translational Science. 1, 1-2, p. 29-31 3 p.

Research output: Contribution to journalEditorial

Cell- and Tissue-Based Therapy
Heart Failure
11 Citations (Scopus)

Defining HFpEF: Where do we draw the line?

Borlaug, B. A., Feb 1 2016, In : European Heart Journal. 37, 5, p. 463-465 3 p.

Research output: Contribution to journalArticle

Stroke Volume
Heart Failure
15 Citations (Scopus)

Differential response to low-dose dopamine or low-dose nesiritide in acute heart failure with reduced or preserved ejection fraction

Wan, S. H., Stevens, S. R., Borlaug, B. A., Anstrom, K. J., Deswal, A., Felker, G. M., Givertz, M. M., Bart, B. A., Tang, W. H. W., Redfield, M. M. & Chen, H. H., Aug 1 2016, In : Circulation: Heart Failure. 9, 8, e002593.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Dopamine
Heart Failure
Placebos
Urine
3 Citations (Scopus)

Getting at the Heart of Central Obesity and the Metabolic Syndrome

Borlaug, B. A. & Reddy, Y. N. V., Jun 1 2016, In : Circulation: Cardiovascular Imaging. 9, 6, e005110.

Research output: Contribution to journalEditorial

Abdominal Obesity
Diabetes Mellitus
Body Mass Index
Blood Pressure
Hypertension
38 Citations (Scopus)

Heart Failure With Preserved Ejection Fraction

Reddy, Y. N. V. & Borlaug, B. A., 2016, (Accepted/In press) In : Current Problems in Cardiology.

Research output: Contribution to journalArticle

Heart Failure
Health Expenditures
Obesity
Hypertension
Morbidity
50 Citations (Scopus)

High-Output Heart Failure: A 15-Year Experience

Reddy, Y. N. V., Melenovsky, V., Redfield, M. M., Nishimura, R. A. & Borlaug, B. A., Aug 2 2016, In : Journal of the American College of Cardiology. 68, 5, p. 473-482 10 p.

Research output: Contribution to journalArticle

Heart Failure
Hemodynamics
Vascular Resistance
Liver Diseases
Obesity

High-Output Heart Failure in Sickle Cell Anemia

Reddy, Y. N. V. & Borlaug, B. A., Sep 1 2016, In : JACC: Cardiovascular Imaging. 9, 9, p. 1122-1123 2 p.

Research output: Contribution to journalLetter

Sickle Cell Anemia
Heart Failure
42 Citations (Scopus)

Impaired Pulmonary Diffusion in Heart Failure With Preserved Ejection Fraction

Olson, T. P., Johnson, B. D. & Borlaug, B. A., Jun 1 2016, In : JACC: Heart Failure. 4, 6, p. 490-498 9 p.

Research output: Contribution to journalArticle

Heart Failure
Exercise
Lung
Carbon Monoxide
Gases
32 Citations (Scopus)

Impaired right ventricular-pulmonary arterial coupling and effect of sildenafil in heart failure with preserved ejection fraction

Hussain, I., Mohammed, S. F., Forfia, P. R., Lewis, G. D., Borlaug, B. A., Gallup, D. S. & Redfield, M. M., Apr 1 2016, In : Circulation: Heart Failure. 9, 4, e002729.

Research output: Contribution to journalArticle

Heart Failure
Right Ventricular Dysfunction
Lung
Oxygen Consumption
Right Ventricular Function
63 Citations (Scopus)

Inhaled Sodium Nitrite Improves Rest and Exercise Hemodynamics in Heart Failure with Preserved Ejection Fraction

Borlaug, B. A., Melenovsky, V. & Koepp, K. E., Sep 16 2016, In : Circulation Research. 119, 7, p. 880-886 7 p.

Research output: Contribution to journalArticle

Sodium Nitrite
Nitrites
Heart Failure
Hemodynamics
Pulmonary Wedge Pressure
7 Citations (Scopus)

Is HFpEF one disease or many?

Borlaug, B. A., Feb 16 2016, In : Journal of the American College of Cardiology. 67, 6, p. 671-673 3 p.

Research output: Contribution to journalArticle

Exercise Tolerance
Left Ventricular Function
Stroke Volume
Heart Failure
Hemodynamics
52 Citations (Scopus)

Myocardial iron content and mitochondrial function in human heart failure: A direct tissue analysis

Melenovsky, V., Petrak, J., Mracek, T., Benes, J., Borlaug, B. A., Nuskova, H., Pluhacek, T., Spatenka, J., Kovalcikova, J., Drahota, Z., Kautzner, J., Pirk, J. & Houstek, J., 2016, (Accepted/In press) In : European Journal of Heart Failure.

Research output: Contribution to journalArticle

Iron
Heart Failure
Enzymes
Electron Transport
Citric Acid Cycle
282 Citations (Scopus)

Phenotype-specific treatment of heart failure with preserved ejection fraction

Shah, S. J., Kitzman, D. W., Borlaug, B. A., Van Heerebeek, L., Zile, M. R., Kass, D. A. & Paulus, W. J., Jul 5 2016, In : Circulation. 134, 1, p. 73-90 18 p.

Research output: Contribution to journalArticle

Treatment Failure
Heart Failure
Phenotype
Cyclic GMP
Muscle Weakness

Reply: Nitrites/nitrates in heart failure with preserved ejection fraction

Borlaug, B. A., Koepp, K. E. & Melenovsky, V., Mar 22 2016, In : Journal of the American College of Cardiology. 67, 11, p. 1383-1384 2 p.

Research output: Contribution to journalArticle

Sodium Nitrite
Exercise Tolerance
Nitrites
Left Ventricular Function
Nitrates
1 Citation (Scopus)

Right ventricular dysfunction and pulmonary hypertension in heart failure with preserved ejection fraction

Obokata, M. & Borlaug, B. A., Dec 1 2016, In : European Journal of Heart Failure. 18, 12, p. 1488-1490 3 p.

Research output: Contribution to journalEditorial

Right Ventricular Dysfunction
Pulmonary Hypertension
Heart Ventricles
Heart Failure
Hemodynamics
3 Citations (Scopus)

The Lungs in Heart Failure: Not an Innocent Bystander

Borlaug, B. A. & Olson, T. P., Jun 1 2016, In : JACC: Heart Failure. 4, 6, p. 450-452 3 p.

Research output: Contribution to journalEditorial

Heart Failure
Smoking
Hypertension
Lung
3 Citations (Scopus)

The reservoir-wave approach to characterize pulmonary vascular-right ventricular interactions in humans

Ghimire, A., Andersen, M. J., Burrowes, L. M., Bouwmeester, C., Grant, A. D., Belenkie, I., Fine, N. M., Borlaug, B. A. & Tyberg, J. V., Dec 1 2016, In : Journal of Applied Physiology. 121, 6, p. 1348-1353 6 p.

Research output: Contribution to journalArticle

Blood Vessels
Pulmonary Artery
Pressure
Lung
Pulmonary Wedge Pressure
2015
8 Citations (Scopus)

Associations of alterations in pulsatile arterial load with left ventricular longitudinal strain

Ye, Z., Coutinho, T., Pellikka, P., Vilarraga, H. R., Borlaug, B. A. & Kullo, I. J., Aug 5 2015, In : American Journal of Hypertension. 28, 11, p. 1325-1331 7 p.

Research output: Contribution to journalArticle

Compliance
Vascular Stiffness
Left Ventricular Function
Manometry
Electric Impedance
4 Citations (Scopus)

Determinants and Correlates of Exercise Capacity in Heart Failure

Borlaug, B. A. & Reddy, Y. N. V., Oct 1 2015, In : JACC: Heart Failure. 3, 10, p. 815-817 3 p., 347.

Research output: Contribution to journalArticle

Low Cardiac Output
Stress Echocardiography
Exercise Tolerance
Ventricular Function
Oxygen Consumption
82 Citations (Scopus)

Differential hemodynamic effects of exercise and volume expansion in people with and without heart failure

Andersen, M. J., Olson, T. P., Melenovsky, V., Kane, G. M. & Borlaug, B. A., 2015, In : Circulation: Heart Failure. 8, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Heart Failure
Hemodynamics
Exercise
Pulmonary Wedge Pressure
Cardiac Output
14 Citations (Scopus)

Effects of cardiac resynchronization therapy on cardiac remodeling and contractile function: Results from resynchronization reverses remodeling in systolic left ventricular dysfunction (REVERSE)

St John Sutton, M., Cerkvenik, J., Borlaug, B. A., Daubert, C., Gold, M. R., Ghio, S., Chirinos, J. A., Linde, C. & Ky, B., Sep 1 2015, In : Journal of the American Heart Association. 4, 9, e002054.

Research output: Contribution to journalArticle

Cardiac Resynchronization Therapy
Left Ventricular Dysfunction
Heart Failure
Stroke
Mortality
38 Citations (Scopus)

Effects of Sildenafil on Ventricular and Vascular Function in Heart Failure with Preserved Ejection Fraction

Borlaug, B. A., Lewis, G. D., McNulty, S. E., Semigran, M. J., Lewinter, M., Chen, H. H., Lin, G. D., Deswal, A., Margulies, K. B. & Redfield, M. M., May 4 2015, In : Circulation: Heart Failure. 8, 3, p. 533-541 9 p.

Research output: Contribution to journalArticle

Ventricular Function
Blood Vessels
Heart Failure
Phosphodiesterase 5 Inhibitors
Placebos
45 Citations (Scopus)

Enhanced pulmonary vasodilator reserve and abnormal right ventricular: pulmonary artery coupling in heart failure with preserved ejection fraction

Andersen, M. J., Hwang, S. J., Kane, G. M., Melenovsky, V., Olson, T. P., Fetterly, K. & Borlaug, B. A., May 1 2015, In : Circulation. Heart failure. 8, 3, p. 542-550 9 p.

Research output: Contribution to journalArticle

Vasodilator Agents
Pulmonary Artery
Heart Failure
Lung
Dobutamine
12 Citations (Scopus)

Exercise intolerance in heart failure with preserved ejection fraction: what does the heart have to do with it?

Little, W. C. & Borlaug, B. A., Mar 1 2015, In : Circulation. Heart failure. 8, 2, p. 233-235 3 p.

Research output: Contribution to journalArticle

Exercise Tolerance
Pulmonary Hypertension
Oxygen Consumption
Cardiac Output
Vascular Resistance
59 Citations (Scopus)

Exercise training as therapy for heart failure current status and future directions

Fleg, J. L., Cooper, L. S., Borlaug, B. A., Haykowsky, M. J., Kraus, W. E., Levine, B. D., Pfeffer, M. A., Pia, I. L., Poole, D. C., Reeves, G. R., Whellan, D. J. & Kitzman, D. W., 2015, In : Circulation: Heart Failure. 8, 1, p. 209-220 12 p.

Research output: Contribution to journalArticle

Exercise Therapy
Exercise Tolerance
Heart Failure
Exercise
Therapeutics
42 Citations (Scopus)

Galectin-3 in heart failure with preservedejection fraction. A RELAX trial substudy (phosphodiesterase-5 inhibition to improve clinical status and exercise capacity in diastolic heartfailure).

Abou Ezzeddine, O., Haines, P., Stevens, S., Nativi-Nicolau, J., Felker, G. M., Borlaug, B. A., Chen, H. H., Tracy, R. P., Braunwald, E. & Redfield, M. M., Mar 1 2015, In : JACC: Heart Failure. 3, 3, p. 245-252 8 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Galectin 3
Heart Failure
Exercise
Fibrosis
14 Citations (Scopus)

Impact of chronic changes in arterial compliance and resistance on left ventricular ageing in humans

Wohlfahrt, P., Redfield, M. M., Melenovsky, V., Lopez-Jimenez, F., Rodeheffer, R. J. & Borlaug, B. A., Jan 1 2015, In : European Journal of Heart Failure. 17, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Compliance
Vascular Resistance
Echocardiography
Heart Rate
4 Citations (Scopus)

In Search of New Targets and Endpoints in Heart Failure With Preserved Ejection Fraction

Borlaug, B. A., Jun 1 2015, In : JACC: Heart Failure. 3, 6, p. 475-477 3 p.

Research output: Contribution to journalArticle

Pulmonary Wedge Pressure
Diastole
Exercise Test
Pulmonary Hypertension
Stroke Volume
195 Citations (Scopus)

Isosorbide mononitrate in heart failure with preserved ejection fraction

Redfield, M. M., Anstrom, K. J., Levine, J. A., Koepp, G. A., Borlaug, B. A., Chen, H. H., LeWinter, M. M., Joseph, S. M., Shah, S. J., Semigran, M. J., Felker, G. M., Cole, R. T., Reeves, G. R., Tedford, R. J., Tang, W. H. W., McNulty, S. E., Velazquez, E. J., Shah, M. R. & Braunwald, E., Dec 10 2015, In : New England Journal of Medicine. 373, 24, p. 2314-2324 11 p.

Research output: Contribution to journalArticle

isosorbide-5-mononitrate
Heart Failure
Placebos
Brain Natriuretic Peptide
Quality of Life
143 Citations (Scopus)

Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction

Melenovsky, V., Hwang, S. J., Redfield, M. M., Zakeri, R., Lin, G. D. & Borlaug, B. A., Mar 20 2015, In : Circulation: Heart Failure. 8, 2, p. 295-303 9 p.

Research output: Contribution to journalArticle

Left Atrial Function
Atrial Remodeling
Heart Failure
Atrial Pressure
Atrial Fibrillation
4 Citations (Scopus)

Low-flow, low-gradient severe aortic stenosis in the setting of constrictive pericarditis: Clinical characteristics, echocardiographic features, and outcomes

Tsang, M. Y. C., Choi, J. O., Borlaug, B. A., Greason, K. L., Cha, S. S., Nishimura, R. A. & Oh, J. K., May 1 2015, In : Circulation: Cardiovascular Imaging. 8, 7, e002812.

Research output: Contribution to journalArticle

Constrictive Pericarditis
Aortic Valve Stenosis
Stroke Volume
Thoracic Surgery
Echocardiography
47 Citations (Scopus)

Lung congestion in chronic heart failure: Haemodynamic, clinical, and prognostic implications

Melenovsky, V., Andersen, M. J., Andress, K., Reddy, Y. N. & Borlaug, B. A., Nov 1 2015, In : European Journal of Heart Failure. 17, 11, p. 1161-1171 11 p.

Research output: Contribution to journalArticle

Heart Failure
Hemodynamics
Lung
Pulmonary Artery
Right Ventricular Dysfunction

Moving beyond cardio-centricity in heart failure risk stratification

Borlaug, B. A., Oct 27 2015, In : Circulation. 132, 17, p. 1602-1603 2 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Veterans
HIV Infections
Heart Failure
22 Citations (Scopus)

Nitrate's effect on activity tolerance in heart failure with preserved ejection fraction trial rationale and design

Zakeri, R., Levine, J. A., Koepp, G. A., Borlaug, B. A., Chirinos, J. A., LeWinter, M., Van Buren, P., Dvila-Romn, V. G., De Las Fuentes, L., Khazanie, P., Hernandez, A., Anstrom, K. & Redfield, M. M., 2015, In : Circulation: Heart Failure. 8, 1, p. 221-228 8 p.

Research output: Contribution to journalArticle

Nitro Compounds
Exercise Tolerance
Nitrates
Stroke Volume
Heart Failure
1 Citation (Scopus)

Response to letter regarding article, Effects of Sildenafil on ventricular and vascular function in heart failure with preserved ejection fraction

Borlaug, B. A., Chen, H. H., Lin, G. D., Redfield, M. M., Lewis, G. D., Semigran, M. J., McNulty, S. E., LeWinter, M., Deswal, A. & Margulies, K. B., May 1 2015, In : Circulation: Heart Failure. 8, 4, p. 840 1 p.

Research output: Contribution to journalArticle

Exercise Therapy
Sodium Chloride
Heart Failure
Hemodynamics