• 13283 Citations
  • 55 Scopus h-Index
20052020
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Research Output 2005 2020

2015
107 Citations (Scopus)

Sodium Nitrite Improves Exercise Hemodynamics and Ventricular Performance in Heart Failure with Preserved Ejection Fraction

Borlaug, B. A., Koepp, K. E. & Melenovsky, V., Oct 13 2015, In : Journal of the American College of Cardiology. 66, 15, p. 1672-1682 11 p.

Research output: Contribution to journalArticle

Sodium Nitrite
Nitrites
Heart Failure
Hemodynamics
Exercise
4 Citations (Scopus)

Stage B heart failure: Is it more common than we think?

Oh, J. K. & Borlaug, B. A., Jan 27 2015, In : Journal of the American College of Cardiology. 65, 3, p. 267-269 3 p.

Research output: Contribution to journalArticle

Exercise Tolerance
Left Ventricular Hypertrophy
Heart Failure
2 Citations (Scopus)

Taking aim at pulmonary hypertension in heart failure with preserved ejection fraction

Borlaug, B. A., Oct 7 2015, In : European Heart Journal. 36, 38, p. 2574-2575 2 p.

Research output: Contribution to journalArticle

Phosphodiesterase 5 Inhibitors
Pulmonary Hypertension
Heart Failure
Hemodynamics
Sildenafil Citrate
4 Citations (Scopus)

The interventional heart failure initiative: A mission statement for the next generation of invasive cardiologists

Kapur, N. K., Dimas, V., Sorajja, P., Borlaug, B. A., Fang, J., Kern, M. & Naidu, S. S., Aug 1 2015, In : Catheterization and Cardiovascular Interventions. 86, 2, p. 353-355 3 p.

Research output: Contribution to journalArticle

Interdisciplinary Communication
Diffusion of Innovation
International Cooperation
Cardiac Catheterization
Cardiology
2014
22 Citations (Scopus)

A randomized pilot study of aortic waveform guided therapy in chronic heart failure.

Borlaug, B. A., Olson, T. P., Abdelmoneim Mohamed, S., Melenovsky, V., Sorrell, V. L., Noonan, K., Lin, G. D. & Redfield, M. M., 2014, In : Journal of the American Heart Association. 3, 2

Research output: Contribution to journalArticle

Heart Failure
Arterial Pressure
Therapeutics
Exercise
Arm
Heart Failure
Therapeutics
42 Citations (Scopus)

Effects of an interatrial shunt on rest and exercise hemodynamics: Results of a computer simulation in heart failure

Kaye, D., Shah, S. J., Borlaug, B. A., Gustafsson, F., Komtebedde, J., Kubo, S., Magnin, C., Maurer, M. S., Feldman, T. & Burkhoff, D., 2014, In : Journal of Cardiac Failure. 20, 3, p. 212-221 10 p.

Research output: Contribution to journalArticle

Pulmonary Wedge Pressure
Cardiac Output
Computer Simulation
Heart Failure
Hemodynamics
27 Citations (Scopus)

Effects of healthy aging on the cardiopulmonary hemodynamic response to exercise

Van Empel, V. P. M., Kaye, D. M. & Borlaug, B. A., Jul 1 2014, In : American Journal of Cardiology. 114, 1, p. 131-135 5 p.

Research output: Contribution to journalArticle

Hemodynamics
Exercise
Heart Failure
Pulmonary Artery
Pressure
10 Citations (Scopus)

Exercise haemodynamics and outcome in patients with dyspnoea

Borlaug, B. A., Nov 21 2014, In : European Heart Journal. 35, 44, p. 3085-3087 3 p.

Research output: Contribution to journalArticle

Stroke Volume
Dyspnea
Heart Failure
Hemodynamics
Exercise
5 Citations (Scopus)

Fatness, fitness, stiffness, and age: How does it lead to heart failure?

Borlaug, B. A., 2014, In : JACC: Heart Failure. 2, 3, p. 247-249 3 p.

Research output: Contribution to journalArticle

Diastolic Heart Failure
Ventricular Remodeling
Physical Fitness
Echocardiography
Myocardium
22 Citations (Scopus)

Heart failure with preserved ejection fraction: Current understandings and challenges

Andersen, M. J. & Borlaug, B. A., 2014, In : Current Cardiology Reports. 16, 7, 501.

Research output: Contribution to journalArticle

Heart Failure
Therapeutics
Comorbidity
Hospitalization
Population
80 Citations (Scopus)

Impact of atrial fibrillation on exercise capacity in heart failure with preserved ejection fraction a relax trial ancillary study

Zakeri, R., Borlaug, B. A., McNulty, S. E., Mohammed, S. F., Lewis, G. D., Semigran, M. J., Deswal, A., LeWinter, M., Hernandez, A. F., Braunwald, E. & Redfield, M. M., 2014, In : Circulation: Heart Failure. 7, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Heart Failure
Exercise
Type 5 Cyclic Nucleotide Phosphodiesterases
Troponin C
44 Citations (Scopus)

Impact of general and central adiposity onventricular-arterial aging in women and men

Wohlfahrt, P., Redfield, M. M., Lopez-Jimenez, F., Melenovsky, V., Kane, G. M., Rodeheffer, R. J. & Borlaug, B. A., Oct 1 2014, In : JACC: Heart Failure. 2, 5, p. 490-499 10 p.

Research output: Contribution to journalArticle

Adiposity
Abdominal Obesity
Weight Loss
Weight Gain
Heart Failure
26 Citations (Scopus)
Heart Failure
Hemodynamics
Exercise
Oxygen
Hypertension
105 Citations (Scopus)

Implications of coronary artery disease in heart failure with preserved ejection fraction

Hwang, S. J., Melenovsky, V. & Borlaug, B. A., Jul 1 2014, In : Journal of the American College of Cardiology. 63, 25 PART A, p. 2817-2827 11 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Heart Failure
Mortality
Hemodynamics
Confidence Intervals
13 Citations (Scopus)

Interatrial pressure gradients during simulated obstructive sleep apnea: A catheter-based study

Konecny, T., Khanna, A. D., Novak, J., Jama, A. A., Zawadowski, G. M., Orban, M., Pressman, G., Bukartyk, J., Kara, T., Cetta, F., Borlaug, B. A., Somers, V. & Reeder, G. S., Dec 1 2014, In : Catheterization and Cardiovascular Interventions. 84, 7, p. 1138-1145 8 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Catheters
Pressure
Atrial Pressure
Heart Atria
20 Citations (Scopus)

Invasive assessment of pulmonary hypertension time for a more fluid approach?

Borlaug, B. A., 2014, In : Circulation: Heart Failure. 7, 1, p. 2-4 3 p.

Research output: Contribution to journalArticle

Pulmonary Wedge Pressure
Fluid Therapy
Cardiac Catheterization
Diagnostic Errors
Pulmonary Hypertension
21 Citations (Scopus)

Invasive Hemodynamic Characterization of Heart Failure with Preserved Ejection Fraction

Andersen, M. J. & Borlaug, B. A., 2014, In : Heart Failure Clinics. 10, 3, p. 435-444 10 p.

Research output: Contribution to journalArticle

Severity of Illness Index
Heart Function Tests
Diastole
Blood Flow Velocity
Systole
55 Citations (Scopus)

Mechanisms of exercise intolerance in heart failure with preserved ejection fraction

Borlaug, B. A., 2014, In : Circulation Journal. 78, 1, p. 20-32 13 p.

Research output: Contribution to journalArticle

Heart Failure
Exercise
Signs and Symptoms
Blood Vessels
Comorbidity
1 Citation (Scopus)

MY APPROACH to heart failure with preserved ejection fraction

Borlaug, B. A., 2014, In : Trends in Cardiovascular Medicine. 24, 8, p. 369-370 2 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptor Antagonists
Exercise Therapy
Exercise Tolerance
Exercise Test
Angiotensin-Converting Enzyme Inhibitors
11 Citations (Scopus)

Relationships between biomarkers and left ventricular filling pressures at rest and during exercise in patients after myocardial infarction

Andersen, M. J., Ersbøll, M., Bro-Jeppesen, J., Møller, J. E., Hassager, C., Køber, L., Borlaug, B. A., Goetze, J. P. & Gustafsson, F., Dec 1 2014, In : Journal of Cardiac Failure. 20, 12, p. 959-967 9 p.

Research output: Contribution to journalArticle

Pulmonary Wedge Pressure
Ventricular Pressure
Biomarkers
Myocardial Infarction
Exercise
Aortic Valve Stenosis
Nitroprusside
Stroke Volume
Hypertension
20 Citations (Scopus)

Resting ventricular-vascular function and exercise capacity in heart failure with preserved ejection fraction: a RELAX trial ancillary study.

Mohammed, S. F., Borlaug, B. A., McNulty, S., Lewis, G. D., Lin, G. D., Zakeri, R., Semigran, M. J., LeWinter, M., Hernandez, A. F., Braunwald, E. & Redfield, M. M., 2014, In : Circulation. Heart failure. 7, 4, p. 580-589 10 p.

Research output: Contribution to journalArticle

Ventricular Function
Blood Vessels
Heart Failure
Oxygen Consumption
Exercise
229 Citations (Scopus)

Right heart dysfunction in heart failure with preserved ejection fraction

Melenovsky, V., Hwang, S. J., Lin, G. D., Redfield, M. M. & Borlaug, B. A., Dec 21 2014, In : European Heart Journal. 35, 48, p. 3452-3462 11 p.

Research output: Contribution to journalArticle

Heart Failure
Right Ventricular Dysfunction
Pulmonary Artery
Pressure
Atrial Fibrillation
40 Citations (Scopus)

Strain improves risk prediction beyond ejection fraction in chronic systolic heart failure.

Zhang, K. W., French, B., May Khan, A., Plappert, T., Fang, J. C., Sweitzer, N. K., Borlaug, B. A., Chirinos, J. A., St John Sutton, M., Cappola, T. P. & Ky, B., 2014, In : Journal of the American Heart Association. 3, 1

Research output: Contribution to journalArticle

Systolic Heart Failure
Area Under Curve
Heart Failure
Heart-Assist Devices
Heart Transplantation
25 Citations (Scopus)

The hemodynamic basis of exercise intolerance in tricuspid regurgitation

Andersen, M. J., Nishimura, R. A. & Borlaug, B. A., Nov 1 2014, In : Circulation: Heart Failure. 7, 6, p. 911-917 7 p.

Research output: Contribution to journalArticle

Tricuspid Valve Insufficiency
Hemodynamics
Exercise
Pulmonary Wedge Pressure
Lung
204 Citations (Scopus)

The pathophysiology of heart failure with preserved ejection fraction

Borlaug, B. A., 2014, In : Nature Reviews Cardiology. 11, 9, p. 507-515 9 p.

Research output: Contribution to journalArticle

Heart Failure
Left Atrial Function
Left Ventricular Dysfunction
Life Expectancy
Biological Availability

The sHunt for better breathing in heart failure with preserved ejection fraction

Borlaug, B. A., 2014, In : European Journal of Heart Failure. 16, 7, p. 709-711 3 p.

Research output: Contribution to journalArticle

Left Atrial Function
Prosthesis Implantation
Atrial Septum
Atrial Pressure
Cardiac Catheterization
20 Citations (Scopus)

Use of metformin in diseases of aging

Miles, J. M., Rule, A. D. & Borlaug, B. A., 2014, In : Current Diabetes Reports. 14, 6, 490.

Research output: Contribution to journalArticle

Metformin
Heart Failure
Risk Reduction Behavior
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
2013
1 Citation (Scopus)

Acute effects of atrial fibrillation on atrial and ventricular function: A simultaneous invasive-echocardiographic hemodynamic study

Dong, Y. X., Madhavan, M., Wu, J. H., Oh, J. K., Mitsuru, M., Powell, B. D., Dong, K., Yang, Y. Z., Hodge, D. O., Nishimura, R. A., Packer, D. L., Borlaug, B. A. & Cha, Y-M., Nov 30 2013, In : International Journal of Cardiology. 169, 6

Research output: Contribution to journalArticle

Atrial Function
Left Atrial Function
Ventricular Function
Left Ventricular Function
Atrial Fibrillation
3 Citations (Scopus)

Aldosterone antagonism for HFpEF

Borlaug, B. A., May 2013, In : Nature Reviews Cardiology. 10, 5, p. 244-246 3 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptor Antagonists
Aldosterone
Heart Failure
Morbidity
Mortality
152 Citations (Scopus)

Cardiac output response to exercise in relation to metabolic demand in heart failure with preserved ejection fraction

Abudiab, M. M., Redfield, M. M., Melenovsky, V., Olson, T. P., Kass, D. A., Johnson, B. D. & Borlaug, B. A., 2013, In : European Journal of Heart Failure. 15, 7, p. 776-785 10 p.

Research output: Contribution to journalArticle

Cardiac Output
Heart Failure
Exercise
Pressure
Stroke Volume
125 Citations (Scopus)
Pulmonary Hypertension
Heart Failure
Hemodynamics
Stroke Volume
Pulmonary Artery

Digging deeper into dyspnea

Eleid, M., Borlaug, B. A. & Mulvagh, S., Mar 2013, In : American Journal of Medicine. 126, 3

Research output: Contribution to journalArticle

Constrictive Pericarditis
X Ray Computed Tomography
Cardiac Catheterization
Dyspnea
27 Citations (Scopus)

Effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiency

Lam, C. S. P., Shah, A. M., Borlaug, B. A., Cheng, S., Verma, A., Izzo, J., Oparil, S., Aurigemma, G. P., Thomas, J. D., Pitt, B., Zile, M. R. & Solomon, S. D., Mar 1 2013, In : European Heart Journal. 34, 9, p. 676-683 8 p.

Research output: Contribution to journalArticle

Mechanics
Antihypertensive Agents
Blood Pressure
Vascular Stiffness
Heart Failure
615 Citations (Scopus)

Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: A randomized clinical trial

Redfield, M. M., Chen, H. H., Borlaug, B. A., Semigran, M. J., Lee, K. L., Lewis, G., LeWinter, M. M., Rouleau, J. L., Bull, D. A., Mann, D. L., Deswal, A., Stevenson, L. W., Givertz Elizabeth O Ofili, M. M., O'Connor, C. M., Felker, G. M., Goldsmith, S. R., Bart, B. A., McNulty, S. E., Ibarra, J. C., Lin, G. D. & 9 others, Oh, J. K., Patel, M. R., Kim, R. J., Tracy, R. P., Velazquez, E. J., Anstrom, K. J., Hernandez, A. F., Mascette, A. M. & Braunwald, E., Mar 27 2013, In : JAMA - Journal of the American Medical Association. 309, 12, p. 1268-1277 10 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Randomized Controlled Trials
Heart Failure
Placebos
Exercise

Erratum: WHO Pulmonary Hypertension Group 2: Pulmonary hypertension due to left heart disease in the adult. A consensus statement of the PH council of the ISHLT JHLT 2012 (Journal of Heart and Lung Transplantation (2012) 31:9 (913-933))

Fang, J. C., Demarco, T., Givertz, M. M., Borlaug, B. A., Lewis, G. D., Rame, J. E., Gomberg-Maitland, M., Murali, S., Frantz, R., McGlothlin, D., Horn, E. M. & Benza, R. L., Feb 2013, In : Journal of Heart and Lung Transplantation. 32, 2, p. 275 1 p.

Research output: Contribution to journalArticle

Heart-Lung Transplantation
Pulmonary Hypertension
Heart Diseases
1 Citation (Scopus)
Vascular Stiffness
Sex Characteristics

Evaluation of tamponade, constrictive, and restrictive physiology

Moscucci, M. & Borlaug, B. A., Oct 5 2013, Grossman & Baim's Cardiac Catheterization, Angiography, and Intervention: Eighth Edition. Wolters Kluwer Health Adis (ESP), p. 489-503 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Citations (Scopus)

Heart failure with preserved and reduced ejection fraction: Different risk profiles for different diseases

Borlaug, B. A., May 21 2013, In : European Heart Journal. 34, 19, p. 1393-1395 3 p.

Research output: Contribution to journalArticle

Heart Failure
4 Citations (Scopus)

Heart rate reduction: It is not just for ventricles anymore

Borlaug, B. A., Nov 19 2013, In : Journal of the American College of Cardiology. 62, 21, p. 1986-1989 4 p.

Research output: Contribution to journalArticle

Systolic Heart Failure
Cardiovascular Agents
Stroke Volume
Heart Ventricles
Heart Failure
102 Citations (Scopus)

Hemodynamic responses to rapid saline loading: The impact of age, sex, and heart failure

Fujimoto, N., Borlaug, B. A., Lewis, G. D., Hastings, J. L., Shafer, K. M., Bhella, P. S., Carrick-Ranson, G. & Levine, B. D., Jan 1 2013, In : Circulation. 127, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

Pulmonary Wedge Pressure
Heart Failure
Hemodynamics
Healthy Volunteers
Arterial Pressure

Hemodynamics for the interventional cardiologist

Kern, M. J. & Borlaug, B. A., Aug 1 2013, SCAI Interventional Cardiology Board Review: Second Edition. Wolters Kluwer Health Adis (ESP), p. 105-120 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hemodynamics
Cardiologists
20 Citations (Scopus)

Invasive measures of afterload in low gradient severe aortic stenosis with preserved ejection fraction

Eleid, M., Nishimura, R. A., Borlaug, B. A. & Sorajja, P., Jul 2013, In : Circulation: Heart Failure. 6, 4, p. 703-710 8 p.

Research output: Contribution to journalArticle

Aortic Valve Stenosis
Vascular Resistance
Stroke Volume
Body Size
Aortic Valve
31 Citations (Scopus)

Left ventricular dysfunction with pulmonary hypertension part 1: Epidemiology, pathophysiology, and definitions

Georgiopoulou, V. V., Kalogeropoulos, A. P., Borlaug, B. A., Gheorghiade, M. & Butler, J., Mar 2013, In : Circulation: Heart Failure. 6, 2, p. 344-354 11 p.

Research output: Contribution to journalArticle

Severity of Illness Index
Left Ventricular Dysfunction
Left Ventricular Function
Pulmonary Hypertension
Stroke Volume
20 Citations (Scopus)

Left ventricular dysfunction with pulmonary hypertension part 2: Prognosis, noninvasive evaluation, treatment, and future research

Kalogeropoulos, A. P., Georgiopoulou, V. V., Borlaug, B. A., Gheorghiade, M. & Butler, J., May 2013, In : Circulation: Heart Failure. 6, 3, p. 584-593 10 p.

Research output: Contribution to journalArticle

Prognathism
Cardiac Resynchronization Therapy
Left Ventricular Dysfunction
Heart Transplantation
Pulmonary Hypertension
91 Citations (Scopus)

Longitudinal changes in left ventricular stiffness a community-based study

Borlaug, B. A., Redfield, M. M., Melenovsky, V., Kane, G. M., Karon, B. L., Jacobsen, S. J. & Rodeheffer, R. J., Sep 2013, In : Circulation: Heart Failure. 6, 5, p. 944-952 9 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Vascular Stiffness
Body Weight Changes
Antihypertensive Agents
Arterial Pressure
265 Citations (Scopus)

Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: The ROSE acute heart failure randomized trial

Chen, H. H., Anstrom, K. J., Givertz, M. M., Stevenson, L. W., Semigran, M. J., Goldsmith, S. R., Bart, B. A., Bull, D. A., Stehlik, J., LeWinter, M. M., Konstam, M. A., Huggins, G. S., Rouleau, J. L., O'Meara, E., Tang, W. H. W., Starling, R. C., Butler, J., Deswal, A., Felker, G. M., O'Connor, C. M. & 14 others, Bonita, R. E., Margulies, K. B., Cappola, T. P., Ofili, E. O., Mann, D. L., Dávila-Román, V. G., McNulty, S. E., Borlaug, B. A., Velazquez, E. J., Lee, K. L., Shah, M. R., Hernandez, A. F., Braunwald, E. & Redfield, M. M., 2013, In : JAMA - Journal of the American Medical Association. 310, 23, p. 2533-2543 11 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Dopamine
Heart Failure
Placebos
Kidney

Profiles in cardiomyopathy and heart failure

Fang, J. C. & Borlaug, B. A., Oct 5 2013, Grossman & Baim's Cardiac Catheterization, Angiography, and Intervention: Eighth Edition. Wolters Kluwer Health Adis (ESP), p. 1011-1044 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cardiomyopathies
Heart Failure
71 Citations (Scopus)

Relationships between right ventricular function, body composition, and prognosis in advanced heart failure

Melenovsky, V., Kotrc, M., Borlaug, B. A., Marek, T., Kovar, J., Malek, I. & Kautzner, J., Oct 29 2013, In : Journal of the American College of Cardiology. 62, 18, p. 1660-1670 11 p.

Research output: Contribution to journalArticle

Right Ventricular Function
Right Ventricular Dysfunction
Body Composition
Cachexia
Heart Failure