• 13283 Citations
  • 55 Scopus h-Index
20052020
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Research Output 2005 2020

2005
465 Citations (Scopus)

Age- and gender-related ventricular-vascular stiffening: A community-based study

Redfield, M. M., Jacobsen, S. J., Borlaug, B. A., Rodeheffer, R. J. & Kass, D. A., Oct 11 2005, In : Circulation. 112, 15, p. 2254-2262 9 p.

Research output: Contribution to journalArticle

Blood Vessels
Blood Pressure
Stroke Volume
Cardiovascular Diseases
Atrial Pressure
45 Citations (Scopus)

Functional impact of rate irregularity in patients with heart failure and atrial fibrillation receiving cardiac resynchronization therapy

Melenovsky, V., Hay, I., Fetics, B. J., Borlaug, B. A., Kramer, A., Pastore, J. M., Berger, R. & Kass, D. A., Apr 2005, In : European Heart Journal. 26, 7, p. 705-711 7 p.

Research output: Contribution to journalArticle

Cardiac Resynchronization Therapy
Atrial Fibrillation
Heart Failure
Ventricular Function
Atrioventricular Block
135 Citations (Scopus)

Sildenafil inhibits β-adrenergic-stimulated cardiac contractility in humans

Borlaug, B. A., Melenovsky, V., Marhin, T., Fitzgerald, P. & Kass, D. A., Oct 25 2005, In : Circulation. 112, 17, p. 2642-2649 8 p.

Research output: Contribution to journalArticle

Adrenergic Agents
Dobutamine
Placebos
Type 5 Cyclic Nucleotide Phosphodiesterases
Sildenafil Citrate
2006
413 Citations (Scopus)

Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction

Borlaug, B. A., Melenovsky, V., Russell, S. D., Kessler, K., Pacak, K., Becker, L. C. & Kass, D. A., Nov 2006, In : Circulation. 114, 20, p. 2138-2147 10 p.

Research output: Contribution to journalArticle

Vasodilator Agents
Heart Failure
Exercise
Cardiac Output
Heart Rate
76 Citations (Scopus)

Mechanisms of Diastolic Dysfunction in Heart Failure

Borlaug, B. A. & Kass, D. A., Nov 2006, In : Trends in Cardiovascular Medicine. 16, 8, p. 273-279 7 p.

Research output: Contribution to journalArticle

Heart Failure
Diastole
Muscle Cells
Extracellular Matrix
Myocardium
679 Citations (Scopus)

Tricuspid annular displacement predicts survival in pulmonary hypertension

Forfia, P. R., Fisher, M. R., Mathai, S. C., Housten-Harris, T., Hemnes, A. R., Borlaug, B. A., Chamera, E., Corretti, M. C., Champion, H. C., Abraham, T. P., Girgis, R. E. & Hassoun, P. M., Nov 1 2006, In : American Journal of Respiratory and Critical Care Medicine. 174, 9, p. 1034-1041 8 p.

Research output: Contribution to journalArticle

Right Ventricular Function
Pulmonary Hypertension
Survival
Cardiac Catheterization
Atrial Remodeling
2007
88 Citations (Scopus)

Beyond Low-Density Lipoprotein Cholesterol. Defining the Role of Low-Density Lipoprotein Heterogeneity in Coronary Artery Disease

Mudd, J. O., Borlaug, B. A., Johnston, P. V., Kral, B. G., Rouf, R., Blumenthal, R. S. & Kwiterovich, P. O., Oct 30 2007, In : Journal of the American College of Cardiology. 50, 18, p. 1735-1741 7 p.

Research output: Contribution to journalArticle

LDL Lipoproteins
LDL Cholesterol
Apolipoproteins B
Coronary Artery Disease
Particle Size
344 Citations (Scopus)

Cardiac structure and ventricular-vascular function in persons with heart failure and preserved ejection fraction from Olmsted County, Minnesota

Lam, C. S. P., Roger, V. L., Rodeheffer, R. J., Bursi, F., Borlaug, B. A., Ommen, S. R., Kass, D. A. & Redfield, M. M., Apr 2007, In : Circulation. 115, 15, p. 1982-1990 9 p.

Research output: Contribution to journalArticle

Ventricular Function
Blood Vessels
Heart Failure
Blood Pressure
Diastole
313 Citations (Scopus)

Cardiovascular Features of Heart Failure With Preserved Ejection Fraction Versus Nonfailing Hypertensive Left Ventricular Hypertrophy in the Urban Baltimore Community. The Role of Atrial Remodeling/Dysfunction

Melenovsky, V., Borlaug, B. A., Rosen, B., Hay, I., Ferruci, L., Morell, C. H., Lakatta, E. G., Najjar, S. S. & Kass, D. A., Jan 16 2007, In : Journal of the American College of Cardiology. 49, 2, p. 198-207 10 p.

Research output: Contribution to journalArticle

Atrial Remodeling
Baltimore
Left Ventricular Hypertrophy
Heart Failure
African Americans
38 Citations (Scopus)

Estimation of central pressure augmentation using automated radial artery tonometry

Melenovsky, V., Borlaug, B. A., Fetics, B., Kessler, K., Shively, L. & Kass, D. A., Jul 2007, In : Journal of Hypertension. 25, 7, p. 1403-1409 7 p.

Research output: Contribution to journalArticle

Radial Artery
Manometry
Pressure
Blood Pressure
Arm
204 Citations (Scopus)

Impact of Arterial Load and Loading Sequence on Left Ventricular Tissue Velocities in Humans

Borlaug, B. A., Melenovsky, V., Redfield, M. M., Kessler, K., Chang, H. J., Abraham, T. P. & Kass, D. A., Oct 16 2007, In : Journal of the American College of Cardiology. 50, 16, p. 1570-1577 8 p.

Research output: Contribution to journalArticle

Doppler Echocardiography
Pulse Wave Analysis
Vascular Resistance
Compliance
Blood Vessels
Ventricular Function
Blood Vessels
Heart Failure
2008
2 Citations (Scopus)
Mitral Valve Stenosis
Heart Failure
Hemodynamics
Exercise
Balloon Valvuloplasty
1 Citation (Scopus)

Ventricular-Arterial Interaction in Patients with Heart Failure and a Preserved Ejection Fraction

Borlaug, B. A., Melenovsky, V. & Kass, D. A., 2008, Diastology: Clinical Approach to Diastolic Heart Failure. Elsevier Inc., p. 403-412 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Heart Failure
176 Citations (Scopus)

Ventricular-Vascular Interaction in Heart Failure

Borlaug, B. A. & Kass, D. A., Jan 2008, In : Heart Failure Clinics. 4, 1, p. 23-36 14 p.

Research output: Contribution to journalArticle

Blood Vessels
Heart Failure
Ventricular Function
Hemodynamics
Therapeutics
2009
259 Citations (Scopus)

Age-associated increases in pulmonary artery systolic pressure in the general population

Lam, C. S. P., Borlaug, B. A., Kane, G. M., Enders, F. T., Rodeheffer, R. J. & Redfield, M. M., May 26 2009, In : Circulation. 119, 20, p. 2663-2670 8 p.

Research output: Contribution to journalArticle

Pulmonary Artery
Blood Pressure
Population
Hypertension
Pressure
259 Citations (Scopus)
Heart Diseases
Heart Failure
Vascular Stiffness
Mortality
Disease Progression
22 Citations (Scopus)

Differentiation of tricuspid regurgitation from constrictive pericarditis: Novel criteria for diagnosis in the cardiac catheterisation laboratory

Jaber, W. A., Sorajja, P., Borlaug, B. A. & Nishimura, R. A., Sep 2009, In : Heart. 95, 17, p. 1449-1454 6 p.

Research output: Contribution to journalArticle

Constrictive Pericarditis
Tricuspid Valve Insufficiency
Ventricular Pressure
Cardiac Catheterization
Blood Pressure
40 Citations (Scopus)

Invasive Hemodynamic Assessment in Heart Failure

Borlaug, B. A. & Kass, D. A., Apr 2009, In : Heart Failure Clinics. 5, 2, p. 217-228 12 p.

Research output: Contribution to journalArticle

Heart Failure
Hemodynamics
Cardiac Catheterization
Cardiac Output
Vascular Resistance
586 Citations (Scopus)

Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction. A Community-Based Study

Lam, C. S. P., Roger, V. L., Rodeheffer, R. J., Borlaug, B. A., Enders, F. T. & Redfield, M. M., Mar 31 2009, In : Journal of the American College of Cardiology. 53, 13, p. 1119-1126 8 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Heart Failure
Pulmonary Artery
Blood Pressure
Pulmonary Wedge Pressure
132 Citations (Scopus)
Takotsubo Cardiomyopathy
Troponin
Brain Natriuretic Peptide
Biomarkers
Metanephrine
7 Citations (Scopus)

Treatment of heart failure with preserved ejection fraction

Borlaug, B. A., 2009, In : Current Treatment Options in Cardiovascular Medicine. 11, 1, p. 79-87 9 p.

Research output: Contribution to journalArticle

Treatment Failure
Heart Failure
Clinical Trials
Systolic Heart Failure
Therapeutics
2010
32 Citations (Scopus)

Caveat medicus! Pulmonary hypertension in the elderly: A word of caution

Boilson, B. A., Schirger, J. A. & Borlaug, B. A., Jan 2010, In : European Journal of Heart Failure. 12, 1, p. 89-93 5 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Heart Failure
Vascular Diseases
Vasodilation
Pulmonary Artery
499 Citations (Scopus)

Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction

Borlaug, B. A., Nishimura, R. A., Sorajja, P., Lam, C. S. P. & Redfield, M. M., Sep 2010, In : Circulation: Heart Failure. 3, 5, p. 588-595 8 p.

Research output: Contribution to journalArticle

Pulmonary Wedge Pressure
Heart Failure
Hemodynamics
Exercise
Dyspnea
364 Citations (Scopus)
Heart Failure
Exercise
Vasodilation
Multiple Abnormalities
Myocardial Contraction
6 Citations (Scopus)

Glycyrrhetinic acid attenuates vascular smooth muscle vasodilatory function in healthy humans

Sobieszczyk, P., Borlaug, B. A., Gornik, H. L., Knauft, W. D. & Beckman, J. A., Nov 2010, In : Clinical Science. 119, 10, p. 437-442 6 p.

Research output: Contribution to journalArticle

Glycyrrhetinic Acid
11-beta-Hydroxysteroid Dehydrogenases
Vascular Smooth Muscle
Hydrocortisone
Blood Vessels
21 Citations (Scopus)

Size, shape, and stamina: The impact of left ventricular geometry on exercise capacity

Lam, C. S. P., Grewal, J., Borlaug, B. A., Ommen, S. R., Kane, G. M., McCully, R. B. & Pellikka, P., May 2010, In : Hypertension. 55, 5, p. 1143-1149 7 p.

Research output: Contribution to journalArticle

Hypertrophy
Metabolic Equivalent
Exercise
Exercise Tolerance
Ventricular Remodeling
25 Citations (Scopus)
Nitroprusside
Catheterization
Echocardiography
Untranslated Regions
Pressure
2011
24 Citations (Scopus)

Bedside assessment of cardiac hemodynamics: The impact of noninvasive testing and examiner experience

From, A. M., Lam, C. S. P., Pitta, S. R., Kumar, P. V., Balbissi, K. A., Booker, J. D., Singh, I. M., Sorajja, P., Reeder, G. S. & Borlaug, B. A., Nov 2011, In : American Journal of Medicine. 124, 11, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

Hemodynamics
Pressure
Natriuretic Peptides
Physical Examination
Confidence Intervals
2 Citations (Scopus)

"Carcinoid-like" tricuspid valvulopathy associated with nephrogenic systemic fibrosis

Gharacholou, S., Maleszewski, J., Borlaug, B. A., Cosio, F. G., Dearani, J. A., Kushwaha, S. S. & Ammash, N. M., Mar 2011, In : Echocardiography. 28, 3

Research output: Contribution to journalArticle

Nephrogenic Fibrosing Dermopathy
Carcinoid Tumor
Tricuspid Valve
Carcinoid Heart Disease
Biopsy
197 Citations (Scopus)

Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum

Borlaug, B. A. & Redfield, M. M., May 10 2011, In : Circulation. 123, 18, p. 2006-2013 8 p.

Research output: Contribution to journalArticle

Diastolic Heart Failure
Systolic Heart Failure
Ventricular Remodeling
Disease Progression
Heart Failure
121 Citations (Scopus)

Diastolic relaxation and compliance reserve during dynamic exercise in heart failure with preserved ejection fraction

Borlaug, B. A., Jaber, W. A., Ommen, S. R., Lam, C. S. P., Redfield, M. M. & Nishimura, R. A., Jun 2011, In : Heart. 97, 12, p. 964-969 6 p.

Research output: Contribution to journalArticle

Compliance
Heart Failure
Exercise
Ventricular Pressure
Diastole
8 Citations (Scopus)

Discerning pulmonary venous from pulmonary arterial hypertension without the help of a catheter

Borlaug, B. A., May 2011, In : Circulation: Heart Failure. 4, 3, p. 235-237 3 p.

Research output: Contribution to journalArticle

Swan-Ganz Catheterization
Central Venous Catheterization
Venous Pressure
Pulmonary Veins
Pulmonary Hypertension
23 Citations (Scopus)

Heart failure with preserved ejection fraction: Pathophysiology and emerging therapies

From, A. M. & Borlaug, B. A., Aug 2011, In : Cardiovascular Therapeutics. 29, 4

Research output: Contribution to journalArticle

Heart Failure
Investigational Therapies
Therapeutics
Clinical Trials
Morbidity
575 Citations (Scopus)

Heart failure with preserved ejection fraction: Pathophysiology, diagnosis, and treatment

Borlaug, B. A. & Paulus, W. J., Mar 2011, In : European Heart Journal. 32, 6, p. 670-679 10 p.

Research output: Contribution to journalArticle

Heart Failure
Cardiovascular Abnormalities
Stroke Volume
Hemodynamics
Clinical Trials
24 Citations (Scopus)

Invasive Hemodynamic Assessment in Heart Failure

Borlaug, B. A. & Kass, D. A., May 2011, In : Cardiology Clinics. 29, 2, p. 269-280 12 p.

Research output: Contribution to journalArticle

Heart Failure
Hemodynamics
Cardiac Catheterization
Cardiac Output
Vascular Resistance

Reply

Borlaug, B. A., Mar 29 2011, In : Journal of the American College of Cardiology. 57, 13, p. 1499-1500 2 p.

Research output: Contribution to journalArticle

Response to de Keulenaer and Brutsaert

Borlaug, B. A. & Redfield, M. M., May 10 2011, In : Circulation. 123, 18, p. 2005 1 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
Elasticity Imaging Techniques
Sex Factors
Elasticity
Left Ventricular Dysfunction
Heart Failure
72 Citations (Scopus)

Ventricular-Vascular Interaction in Heart Failure

Borlaug, B. A. & Kass, D. A., Aug 2011, In : Cardiology Clinics. 29, 3, p. 447-459 13 p.

Research output: Contribution to journalArticle

Blood Vessels
Heart Failure
Ventricular Function
Hemodynamics
Therapeutics
129 Citations (Scopus)

Why are women more likely than men to develop heart failure with preserved ejection fraction?

Scantlebury, D. C. & Borlaug, B. A., Nov 2011, In : Current Opinion in Cardiology. 26, 6, p. 562-568 7 p.

Research output: Contribution to journalArticle

Stroke Volume
Heart Failure
Vascular Stiffness
Ventricular Remodeling
Left Ventricular Function
2012
62 Citations (Scopus)

Biomarkers in acutely decompensated heart failure with preserved or reduced ejection fraction

Bishu, K., Deswal, A., Chen, H. H., Lewinter, M. M., Lewis, G. D., Semigran, M. J., Borlaug, B. A., McNulty, S., Hernandez, A. F., Braunwald, E. & Redfield, M. M., Nov 2012, In : American Heart Journal. 164, 5

Research output: Contribution to journalArticle

Heart Failure
Biomarkers
Renin-Angiotensin System
Natriuretic Peptides
Mineralocorticoid Receptor Antagonists
118 Citations (Scopus)

Comorbidity and ventricular and vascular structure and function in heart failure with preserved ejection fraction a community-based study

Mohammed, S. F., Borlaug, B. A., Roger, V. L., Mirzoyev, S. A., Rodeheffer, R. J., Chirinos, J. A. & Redfield, M. M., Nov 2012, In : Circulation: Heart Failure. 5, 6, p. 710-719 10 p.

Research output: Contribution to journalArticle

Blood Vessels
Comorbidity
Heart Failure
Body Size
Adiposity
170 Citations (Scopus)

Effects of vasodilation in heart failure with preserved or reduced ejection fraction: Implications of distinct pathophysiologies on response to therapy

Schwartzenberg, S., Redfield, M. M., From, A. M., Sorajja, P., Nishimura, R. A. & Borlaug, B. A., Jan 31 2012, In : Journal of the American College of Cardiology. 59, 5, p. 442-451 10 p.

Research output: Contribution to journalArticle

Vasodilation
Heart Failure
Stroke Volume
Nitroprusside
Vasodilator Agents
77 Citations (Scopus)

Electrophysiological and hemodynamic characteristics associated with obesity in patients with atrial fibrillation

Munger, T. M., Dong, Y. X., Masaki, M., Oh, J. K., Mankad, S. V., Borlaug, B. A., Asirvatham, S. J., Shen, W. K., Lee, H. C., Bielinski, S. J., Hodge, D. O., Herges, R. M., Buescher, T. L., Wu, J. H., Ma, C., Zhang, Y., Chen, P. S., Packer, D. L. & Cha, Y-M., Aug 28 2012, In : Journal of the American College of Cardiology. 60, 9, p. 851-860 10 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Obesity
Hemodynamics
Pulmonary Veins
Body Mass Index
32 Citations (Scopus)

Exercise hemodynamics in patients with and without diastolic dysfunction and preserved ejection fraction after myocardial infarction

Andersen, M. J., Ersbll, M., Bro -Jeppesen, J., Gustafsson, F., Hassager, C., Kber, L., Borlaug, B. A., Boesgaard, S., Kjærgaard, J. & Mller, J. E., Jul 2012, In : Circulation: Heart Failure. 5, 4, p. 444-451 8 p.

Research output: Contribution to journalArticle

Hemodynamics
Myocardial Infarction
Exercise
Pulmonary Wedge Pressure
Left Ventricular Dysfunction
11 Citations (Scopus)
Piperazines
Type 5 Cyclic Nucleotide Phosphodiesterases
Phosphodiesterase 5 Inhibitors
Sulfones
Pulmonary Hypertension
83 Citations (Scopus)

PhosphdiesteRasE-5 inhibition to improve CLinical status and EXercise capacity in diastolic heart failure (RELAX) trial: Rationale and design

Redfield, M. M., Borlaug, B. A., Lewis, G. D., Mohammed, S. F., Semigran, M. J., Lewinter, M. M., Deswal, A., Hernandez, A. F., Lee, K. L. & Braunwald, E., Sep 2012, In : Circulation: Heart Failure. 5, 5, p. 653-659 7 p.

Research output: Contribution to journalArticle

Piperazines
Diastolic Heart Failure
Phosphodiesterase 5 Inhibitors
Cardiovascular Agents
Purines
195 Citations (Scopus)

Pulmonary capillary wedge pressure augments right ventricular pulsatile loading

Tedford, R. J., Hassoun, P. M., Mathai, S. C., Girgis, R. E., Russell, S. D., Thiemann, D. R., Cingolani, O. H., Mudd, J. O., Borlaug, B. A., Redfield, M. M., Lederer, D. J. & Kass, D. A., Jan 17 2012, In : Circulation. 125, 2, p. 289-297 9 p.

Research output: Contribution to journalArticle

Pulmonary Wedge Pressure
Compliance
Pulmonary Hypertension
Pulmonary Fibrosis
Right Ventricular Dysfunction
230 Citations (Scopus)

Pulmonary hypertension due to left heart disease

Guazzi, M. & Borlaug, B. A., Aug 21 2012, In : Circulation. 126, 8, p. 975-990 16 p.

Research output: Contribution to journalArticle

Phosphodiesterase 5 Inhibitors
Endothelin Receptors
Left Ventricular Dysfunction
Vasodilator Agents
Pulmonary Hypertension