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Arthur Beyder, MD, PhD

  • 860 Citations
  • 17 Scopus h-Index
19992019
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  • 2 Similar Profiles
Interstitial Cells of Cajal Medicine & Life Sciences
Enterochromaffin Cells Medicine & Life Sciences
Ion Channels Medicine & Life Sciences
Channelopathies Medicine & Life Sciences
NAV1.5 Voltage-Gated Sodium Channel Medicine & Life Sciences
Serotonin Medicine & Life Sciences
Sodium Channels Medicine & Life Sciences
Irritable Bowel Syndrome Medicine & Life Sciences

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Projects

Enterochromaffin cell mechanotransduction and mechanosensitive serotonin release depend on calcium signaling downstream of Piezo2 activation

Beyder, A.

Project: Research project

Mechanisms of mechanotransduction in the enterochromaffin cells

Beyder, A.

Project: Research project

Research Output 1999 2019

In pursuit of the epithelial mechanosensitivity mechanisms

Beyder, A., Jan 1 2019, In : Frontiers in Endocrinology. 10, JAN

Research output: Contribution to journal › Short survey

Open Access
Enteric Nervous System
Serotonin
2 Citations (Scopus)

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D., Yaqoob, U., Cao, S., Revzin, A., Beyder, A., Wang, R. A., Kamath, P. S., Kubes, P. & Shah, V., Jul 1 2019, In : Gastroenterology. 157, 1, p. 193-209.e9

Research output: Contribution to journal › Article

Portal Hypertension
Neutrophils
Endothelial Cells
Liver
RNA Sequence Analysis
7 Citations (Scopus)

Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

Butin-Israeli, V., Bui, T. M., Wiesolek, H. L., Mascarenhas, L., Lee, J. J., Mehl, L. C., Knutson, K. R., Adam, S. A., Goldman, R. D., Beyder, A., Wiesmuller, L., Hanauer, S. B. & Sumagin, R., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 712-726 15 p.

Research output: Contribution to journal › Article

Genomic Instability
Wound Healing
Neutrophils
Homologous Recombination
Inflammation

SCN5A mutation G615E results in NaV1.5 voltage-gated sodium channels with normal voltage-dependent function yet loss of mechanosensitivity

Strege, P. R., Mercado-Perez, A., Mazzone, A., Saito Loftus, Y. A., Bernard, C. E., Farrugia, G. & Beyder, A., Dec 1 2019, In : Channels (Austin, Tex.). 13, 1, p. 287-298 12 p.

Research output: Contribution to journal › Article

Open Access
NAV1.5 Voltage-Gated Sodium Channel
Cardiac Myocytes
Smooth Muscle
Channelopathies
Pressure
9 Citations (Scopus)

A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release

Alcaino, C., Knutson, K. R., Treichel, A. J., Yildiz, G., Strege, P. R., Linden, D. R., Li, J. H., Leiter, A. B., Szurszewski, J. H., Farrugia, G. & Beyder, A., Aug 7 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 32, p. E7632-E7641

Research output: Contribution to journal › Article

Enterochromaffin Cells
Enteroendocrine Cells
Serotonin
Epithelial Cells
Population