Research Output per year
Research Output 1999 2019
Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension
Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D., Yaqoob, U., Cao, S., Revzin, A., Beyder, A., Wang, R. A., Kamath, P. S., Kubes, P. & Shah, V., Jul 1 2019, In : Gastroenterology. 157, 1, p. 193-209.e9Research output: Contribution to journal › Article
Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing
Butin-Israeli, V., Bui, T. M., Wiesolek, H. L., Mascarenhas, L., Lee, J. J., Mehl, L. C., Knutson, K. R., Adam, S. A., Goldman, R. D., Beyder, A., Wiesmuller, L., Hanauer, S. B. & Sumagin, R., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 712-726 15 p.Research output: Contribution to journal › Article
SCN5A mutation G615E results in NaV1.5 voltage-gated sodium channels with normal voltage-dependent function yet loss of mechanosensitivity
Strege, P. R., Mercado-Perez, A., Mazzone, A., Saito Loftus, Y. A., Bernard, C. E., Farrugia, G. & Beyder, A., Dec 1 2019, In : Channels (Austin, Tex.). 13, 1, p. 287-298 12 p.Research output: Contribution to journal › Article
A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release
Alcaino, C., Knutson, K. R., Treichel, A. J., Yildiz, G., Strege, P. R., Linden, D. R., Li, J. H., Leiter, A. B., Szurszewski, J. H., Farrugia, G. & Beyder, A., Aug 7 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 32, p. E7632-E7641Research output: Contribution to journal › Article
Gut development on a full stomach
Beyder, A., Apr 20 2018, (Accepted/In press) In : Nature Reviews Gastroenterology and Hepatology. p. 1-2 2 p.Research output: Contribution to journal › Article
Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased Nav1.5 current and mechanosensitivity
Strege, P. R., Mazzone, A., Bernard, C. E., Neshatian, L., Gibbons, S. J., Saito Loftus, Y. A., Tester, D. J., Calvert, M. L., Mayer, E. A., Chang, L., Ackerman, M. J., Beyder, A. & Farrugia, G., Apr 1 2018, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 314, 4, p. G494-G503Research output: Contribution to journal › Article
The touchy business of gastrointestinal (GI) mechanosensitivity
Treichel, A. J., Farrugia, G. & Beyder, A., Aug 15 2018, In : Brain Research. 1693, p. 197-200 4 p.Research output: Contribution to journal › Article
Whole cell electrophysiology of primary cultured murine enterochromaffin cells
Knutson, K., Strege, P. R., Li, J., Leiter, A. B., Farrugia, G. & Beyder, A., Sep 26 2018, In : Journal of Visualized Experiments. 2018, 139, e58112.Research output: Contribution to journal › Article
47-Year-Old Man With Abdominal Pain and Diarrhea
Codipilly, D. C., Chedid, V. & Beyder, A., Jan 1 2017, (Accepted/In press) In : Mayo Clinic Proceedings.Research output: Contribution to journal › Article
EAVK segment “c” sequence confers Ca2+-dependent changes to the kinetics of full-length human Ano1
Strege, P. R., Gibbons, S. J., Mazzone, A., Bernard, C. E., Beyder, A. & Farrugia, G., Jun 1 2017, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 312, 6, p. G572-G579Research output: Contribution to journal › Article
Human-derived gut microbiota modulates colonic secretion in mice by regulating 5-HT3 receptor expression via acetate production
Bhattarai, Y., Schmidt, B. A., Linden, D. R., Larson, E. D., Grover, M., Beyder, A., Farrugia, G. & Kashyap, P. C., 2017, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 313, 1, p. G80-G87Research output: Contribution to journal › Article
Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4
Alcaino, C., Knutson, K., Gottlieb, P. A., Farrugia, G. & Beyder, A., Feb 7 2017, (Accepted/In press) In : Channels. p. 1-9 9 p.Research output: Contribution to journal › Article
Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release
Strege, P. R., Knutson, K., Eggers, S. J., Li, J. H., Wang, F., Linden, D. R., Szurszewski, J. H., Milescu, L., Leiter, A. B., Farrugia, G. & Beyder, A., Dec 1 2017, In : Scientific Reports. 7, 1, 15650.Research output: Contribution to journal › Article
Expression and function of the Scn5a-encoded voltage-gated sodium channel NaV1.5 in the rat jejunum
Beyder, A., Gibbons, S. J., Mazzone, A., Strege, P. R., Saravanaperumal, S. A., Sha, L., Higgins, S., Eisenman, S. T., Bernard, C. E., Geurts, A., Kline, C. F., Mohler, P. J. & Farrugia, G., Jan 1 2016, In : Neurogastroenterology and Motility. 28, 1, p. 64-73 10 p.Research output: Contribution to journal › Article
Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice
Choi, K. M., Gibbons, S. J., Sha, L., Beyder, A., Verhulst, P. J., Cipriani, G., Phillips, J. E., Bauer, A. J., Ordog, T., Camp, J. J., Ge, X., Bharucha, A. E., Linden, D. R., Szurszewski, J. H., Kashyap, P. C. & Farrugia, G., Jul 1 2016, In : CMGH Cellular and Molecular Gastroenterology and Hepatology. 2, 4, p. 454-467 14 p.Research output: Contribution to journal › Article
Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces
Wang, F., Knutson, K., Alcaino, C., Linden, D. R., Gibbons, S. J., Kashyap, P. C., Grover, M., Oeckler, R., Gottlieb, P. A., Li, H. J., Leiter, A. B., Farrugia, G. & Beyder, A., 2016, (Accepted/In press) In : Journal of Physiology.Research output: Contribution to journal › Article
Mechanosensitive Piezo Channels in the Gastrointestinal Tract
Alcaino, C., Farrugia, G. & Beyder, A., 2016, (Accepted/In press) In : Current Topics in Membranes.Research output: Contribution to journal › Article
TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M
Henström, M., Hadizadeh, F., Beyder, A., Bonfiglio, F., Zheng, T., Assadi, G., Rafter, J., Bujanda, L., Agreus, L., Andreasson, A., Dlugosz, A., Lindberg, G., Schmidt, P. T., Karling, P., Ohlsson, B., Talley, N. J., Simren, M., Walter, S., Wouters, M., Farrugia, G. & 1 others, , Dec 14 2016, (Accepted/In press) In : Gut.Research output: Contribution to journal › Article
A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2+
Strege, P. R., Bernard, C. E., Mazzone, A., Linden, D. R., Beyder, A., Gibbons, S. J. & Farrugia, G., Nov 1 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 9, p. G743-G749Research output: Contribution to journal › Article
Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces
Simonetto, D., Yang, H. Y., Yin, M., de Assuncao, T. M., Kwon, J. H., Hilscher, M., Pan, S., Yang, L., Bi, Y., Beyder, A., Cao, S., Simari, R. D., Ehman, R. L., Kamath, P. S. & Shah, V., Feb 1 2015, In : Hepatology. 61, 2, p. 648-659 12 p.Research output: Contribution to journal › Article
Ranolazine inhibits voltage-gated mechanosensitive sodium channels in human colon circular smooth muscle cells
Neshatian, L., Strege, P. R., Rhee, P. L., Kraichely, R. E., Mazzone, A., Bernard, C. E., Cima, R. R., Larson, D., Dozois, E., Kline, C. F., Mohler, P. J., Beyder, A. & Farrugia, G., Sep 15 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 6, p. G506-G512Research output: Contribution to journal › Article
84-year-old man with night sweats, weight loss, and diarrhea
Ngwa, T. N., Beyder, A. & Vege, S. S., 2014, In : Mayo Clinic Proceedings. 89, 3, p. 409-413 5 p.Research output: Contribution to journal › Article
Loss-of-function of the voltage-gated sodium channel NaV1.5 (Channelopathies) in patients with irritable bowel syndrome
Beyder, A., Mazzone, A., Strege, P. R., Tester, D. J., Saito Loftus, Y. A., Bernard, C. E., Enders, F. T., Ek, W. E., Schmidt, P. T., Dlugosz, A., Lindberg, G., Karling, P., Ohlsson, B., Gazouli, M., Nardone, G., Cuomo, R., Usai-Satta, P., Galeazzi, F., Neri, M., Portincasa, P. & 8 others, , 2014, In : Gastroenterology. 146, 7, p. 1659-1668 10 p.Research output: Contribution to journal › Article
Acute polyarticular gout presenting as Delirium
Wilson, M., Wan, S. H., Beyder, A., Osborn, T. & Beckman, T. J., Jun 2013, In : Journal of Clinical Rheumatology. 19, 4, p. 221-222 2 p.Research output: Contribution to journal › Article
The bioelectrical basis and validity of gastrointestinal extracellular slow wave recordings
Angeli, T. R., Du, P., Paskaranandavadivel, N., Janssen, P. W. M., Beyder, A., Lentle, R. G., Bissett, I. P., Cheng, L. K. & O'Grady, G., Sep 2013, In : Journal of Physiology. 591, 18, p. 4567-4579 13 p.Research output: Contribution to journal › Article
Large atrial myxoma causing dynamic obstruction of the mitral valve and atrial fibrillation
Beyder, A. & Klarich, K. W., 2012, In : Mayo Clinic Proceedings. 87, 2Research output: Contribution to journal › Article
Membrane permeable local anesthetics modulate Na V1.5 mechanosensitivity
Beyder, A., Strege, P. R., Bernard, C. & Farrugia, G., Jul 2012, In : Channels. 6, 4Research output: Contribution to journal › Article
Quantification of gastrointestinal sodium channelopathy
Poh, Y. C., Beyder, A., Strege, P. R., Farrugia, G. & Buist, M. L., Jan 21 2012, In : Journal of Theoretical Biology. 293, p. 41-48 8 p.Research output: Contribution to journal › Article
Ranolazine decreases mechanosensitivity of the voltage-gated sodium ion channel NaV1.5: A novel mechanism of drug action
Beyder, A., Strege, P. R., Reyes, S., Bernard, C. E., Terzic, A., Makielski, J., Ackerman, M. J. & Farrugia, G., Jun 5 2012, In : Circulation. 125, 22, p. 2698-2706 9 p.Research output: Contribution to journal › Article
Ranolazine inhibits shear sensitivity of endogenous Na+ current and spontaneous action potentials in HL-1 cells
Strege, P., Beyder, A., Bernard, C., Crespo-Diaz, R., Behfar, A., Terzic, A., Ackerman, M. J. & Farrugia, G., Nov 2012, In : Channels. 6, 6, p. 457-462 6 p.Research output: Contribution to journal › Article
Targeting ion channels for the treatment of gastrointestinal motility disorders
Beyder, A. & Farrugia, G., Jan 2012, In : Therapeutic Advances in Gastroenterology. 5, 1, p. 5-21 17 p.Research output: Contribution to journal › Article
Altered expression of ano1 variants in human diabetic gastroparesis
Mazzone, A., Bernard, C. E., Strege, P. R., Beyder, A., Galietta, L. J. V., Pasricha, P. J., Rae, J. L., Parkman, H. P., Linden, D. R., Szurszewski, J. H., Ordog, T., Gibbons, S. J. & Farrugia, G., Apr 15 2011, In : Journal of Biological Chemistry. 286, 15, p. 13393-13403 11 p.Research output: Contribution to journal › Article
Biophysically based modeling of the interstitial cells of Cajal: Current status and future perspectives
Lees-Green, R., Du, P., O'Grady, G., Beyder, A., Farrugia, G. & Pullan, A. J., 2011, In : Frontiers in Physiology. JUL, Article 29.Research output: Contribution to journal › Article
Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na+ channel, NAv1.5
Strege, P. R., Bernard, C. E., Kraichely, R. E., Mazzone, A., Sha, L., Beyder, A., Gibbons, S. J., Linden, D. R., Kendrick, M. L., Sarr, M. G., Szurszewski, J. H. & Farrugia, G., Jun 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 6Research output: Contribution to journal › Article
Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo
Tharayil, V. S., Wouters, M. M., Stanich, J. E., Roeder, J. L., Lei, S., Beyder, A., Gomez-Pinilla, P. J., Gershon, M. D., Maroteaux, L., Gibbons, S. J. & Farrugia, G., Apr 2010, In : Neurogastroenterology and Motility. 22, 4Research output: Contribution to journal › Article
Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel
Beyder, A., Rae, J. L., Bernard, C., Strege, P. R., Sachs, F. & Farrugia, G., Dec 2010, In : Journal of Physiology. 588, 24, p. 4969-4985 17 p.Research output: Contribution to journal › Article
T-type Ca2+ channel modulation by otilonium bromide
Strege, P. R., Sha, L., Beyder, A., Bernard, C. E., Perez-Reyes, E., Evangelista, S., Gibbons, S. J., Szurszewski, J. H. & Farrugia, G., May 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 298, 5Research output: Contribution to journal › Article
Electromechanical coupling in the membranes of Shaker-transfected HEK cells
Beyder, A. & Sachs, F., Apr 21 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 16, p. 6626-6631 6 p.Research output: Contribution to journal › Article
Atomic force microscopy analysis of cell volume regulation
Spagnoli, C., Beyder, A., Besch, S. & Sachs, F., Sep 22 2008, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 78, 3, 031916.Research output: Contribution to journal › Article
Drift-free atomic force microscopy measurements of cell height and mechanical properties
Spagnoli, C., Beyder, A., Besch, S. R. & Sachs, F., 2007, In : Review of Scientific Instruments. 78, 3, 036111.Research output: Contribution to journal › Article
Hydrodynamics of torsional probes for atomic force microscopy in liquids
Basak, S., Beyder, A., Spagnoli, C., Raman, A. & Sachs, F., 2007, In : Journal of Applied Physics. 102, 2, 024914.Research output: Contribution to journal › Article
Microfabricated torsion levers optimized for low force and high-frequency operation in fluids
Beyder, A. & Sachs, F., Jun 2006, In : Ultramicroscopy. 106, 8-9, p. 838-846 9 p.Research output: Contribution to journal › Article
Reducing probe dependent drift in atomic force microscope with symmetrically supported torsion levers
Beyder, A., Spagnoli, C. & Sachs, F., May 2006, In : Review of Scientific Instruments. 77, 5, 056105.Research output: Contribution to journal › Article
Spatially resolved detection of attomole quantities of organic molecules localized in picoliter vials using time-of-flight secondary ion mass spectrometry
Braun, R. M., Beyder, A., Xu, J., Wood, M. C., Ewing, A. G. & Winograd, N., Aug 15 1999, In : Analytical Chemistry. 71, 16, p. 3318-3324 7 p.Research output: Contribution to journal › Article