Andrew David Badley, MD

Professor

  • 4784 Citations
  • 38 h-Index
1990 …2020
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  • 9 Similar Profiles
HIV Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
HIV Infections Medicine & Life Sciences
HIV Protease Inhibitors Medicine & Life Sciences
HIV-1 Medicine & Life Sciences
Nelfinavir Medicine & Life Sciences
Cell Death Medicine & Life Sciences

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Projects 1996 2020

HIV
Apoptosis
TNF-Related Apoptosis-Inducing Ligand Receptors
HIV Infections
Virus Diseases

Prime shock and kill for HIV erradication

Badley, A. D.

National Institutes of Health

2/15/141/31/19

Project: Research projectResearch Project

Shock
HIV
T-Lymphocytes
Apoptosis
Human Immunodeficiency Virus Proteins

Enhancing control of HIV by inhibiting TRAILshort

Badley, A. D.

National Institutes of Health

7/2/136/1/15

Project: Research projectHigh Priority, Short Term Project Award

HIV
Natural Killer Cells
HIV Infections
Berlin
Infection

Procaspase 8 Activation by HIV Protease

Badley, A. D.

National Institutes of Health

5/1/044/30/09

Project: Research projectResearch Project

HIV Protease
Caspase 8
Apoptosis
Human Immunodeficiency Virus Proteins
Mutation

Significance of HIV Protease Cleavage of Procaspase 8

Badley, A. D.

National Institutes of Health

9/1/038/31/04

Project: Research projectExploratory/Developmental Grants

HIV Protease
Caspase 8
Apoptosis
T-Lymphocytes
Infection

Research Output 1990 2018

Allogeneic stem cell transplantation alone is unlikely to provide the HIV-1 cure

Cummins, N. W. & Badley, A. D., Jan 1 2018, In : Future Virology. 13, 5, p. 307-308 2 p.

Research output: Contribution to journalEditorial

Stem Cell Transplantation
HIV-1
1 Citations

Both HIV-Infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment

Nie, Z., Aboulnasr, F., Natesampillai, S., Burke, S. P., Krogman, A., Bren, G. D., Chung, T. D. Y., Anderson, J. R., Smart, M. K., Katzmann, D. J., Rajagopalan, G., Cummins, N. W. & Badley, A. D., Feb 1 2018, In : Journal of Immunology. 200, 3, p. 1110-1123 14 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand
Cellular Microenvironment
HIV
TNF-Related Apoptosis-Inducing Ligand Receptors
Proteasome Endopeptidase Complex

Corrections: Both HIV-infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment (Journal of Immunology (2008) 200 (1110-1123) DOI: 10.4049/jimmunol.1701113)

Nie, Z., Aboulnasr, F., Natesampillai, S., Burke, S. P., Krogman, A., Bren, G. D., Chung, T. D. Y., Anderson, J. R., Smart, M. K., Katzmann, D. J., Rajagopalan, G., Cummins, N. W. & Badley, A. D., Feb 1 2018, In : Journal of Immunology. 201, 5, 1 p.

Research output: Contribution to journalComment/debate

Cellular Microenvironment
Allergy and Immunology
HIV
Jurkat Cells
HeLa Cells

HIV protease-generated Casp8p41, when bound and inactivated by Bcl2, is degraded by the proteasome

Natesampillai, S., Cummins, N. W., Nie, Z., Sampath, R., Baker, J. V., Henry, K., Pinzone, M., O'Doherty, U., Polley, E., Bren, G. D., Katzmann, D. J. & Badley, A. D., Jul 1 2018, In : Journal of Virology. 92, 13, e00037-18.

Research output: Contribution to journalArticle

HIV Protease
proteasome endopeptidase complex
Proteasome Endopeptidase Complex
cell death
Cell Death

Transient Loss of HIV-1 DNA in an HIV-1 Positive Patient After Kidney Transplantation: A Case Report

Paim, A. C., Rizza, S., Badley, A. D., Prieto, M., Taler, S. J., Chong, P. P. & Cummins, N. W., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

Kidney Transplantation
HIV-1
DNA