Zhenkun Lou, PhD

Professor

  • 4604 Citations
  • 33 h-Index
20002020
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DNA Damage Medicine & Life Sciences
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DNA Chemical Compounds
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Proteins Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
DNA Repair Medicine & Life Sciences

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Projects 2007 2020

Homologous Recombination
Chemoradiotherapy
DNA Repair
Breast Neoplasms
Neoplasms
Oncogenes
Carcinogenesis
Hypoxia-Inducible Factor 1
Up-Regulation
Glycolysis
DNA Damage
Sumoylation
Neoplasms
Ubiquitination
Carcinogenesis

Research Output 2000 2019

  • 4604 Citations
  • 33 h-Index
  • 84 Article
  • 1 Letter
  • 1 Review article

UFL1 promotes histone H4 ufmylation and ATM activation

Qin, B., Yu, J., Nowsheen, S., Wang, M., Tu, X., Liu, T., Li, H., Wang, L. M. & Lou, Z., Dec 1 2019, In : Nature communications. 10, 1, 1242.

Research output: Contribution to journalArticle

Open Access
ataxia
Ataxia Telangiectasia
enzyme activity
Enzyme activity
Ligases

USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2

Wu, J., Chen, Y., Geng, G., Li, L., Yin, P., Nowsheen, S., Li, Y., Wu, C., Liu, J., Zhao, F., Kim, W., Zhou, Q., Huang, J., Guo, G., Zhang, C., Tu, X., Gao, X., Lou, Z., Luo, K., Qiao, H. & 1 othersYuan, J., May 1 2019, In : Cancer Letters. 449, p. 114-124 11 p.

Research output: Contribution to journalArticle

Checkpoint Kinase 2
DNA Damage
Radiation
Apoptosis
Protein-Serine-Threonine Kinases
2 Citations (Scopus)
Chromatin
Cell Differentiation
Nucleosomes
Genes
Histone Chaperones
1 Citation (Scopus)

ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer

Tu, X., Kahila, M. M., Zhou, Q., Yu, J., Kalari, K. R., Wang, L. M., Harmsen, W. S., Yuan, J., Boughey, J. C., Goetz, M. P., Sarkaria, J. N., Lou, Z. & Mutter, R., Nov 1 2018, In : Molecular Cancer Therapeutics. 17, 11, p. 2462-2472 11 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Radiotherapy
Exome
Homologous Recombination
Neoplasms
6 Citations (Scopus)

Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity

Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T. D., Feb 6 2018, In : Cell Reports. 22, 6, p. 1365-1373 9 p.

Research output: Contribution to journalArticle

Carnitine O-Palmitoyltransferase
Lysine
Phosphopyruvate Hydratase
Isotope Labeling
Mutation