Zhenkun Lou, PhD

Professor

  • 4416 Citations
  • 33 h-Index
20002020
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  • 13 Similar Profiles
DNA Damage Medicine & Life Sciences
DNA Chemical Compounds
Breast Neoplasms Medicine & Life Sciences
Double-Stranded DNA Breaks Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
DNA Repair Medicine & Life Sciences

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Projects 2007 2020

Homologous Recombination
Chemoradiotherapy
DNA Repair
Breast Neoplasms
Neoplasms

The Role of WSB1 in Tumorigenesis

Lou, Z.

National Institutes of Health

9/1/148/31/19

Project: Research projectResearch Project

Oncogenes
Carcinogenesis
Hypoxia-Inducible Factor 1
Up-Regulation
Glycolysis

The Role of MDC1 in Genome Maintenance and Tumor Suppression

Lou, Z.

National Institutes of Health

12/1/0711/30/18

Project: Research projectResearch Project

DNA Damage
Genomic Instability
Maintenance
Genome
Ubiquitination

Regultion of p53 Deubiquitination

Lou, Z.

National Institutes of Health

1/1/113/31/16

Project: Research projectResearch Project

DNA Damage
Sumoylation
Neoplasms
Ubiquitination
Carcinogenesis

Research Output 2000 2018

  • 4416 Citations
  • 33 h-Index
  • 80 Article
  • 1 Letter
  • 1 Review article

ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer

Tu, X., Kahila, M. M., Zhou, Q., Yu, J., Kalari, K. R., Wang, L. M., Harmsen, W. S., Yuan, J., Boughey, J. C., Goetz, M. P., Sarkaria, J. N., Lou, Z. & Mutter, R., Nov 1 2018, In : Molecular cancer therapeutics. 17, 11, p. 2462-2472 11 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Radiotherapy
Exome
Homologous Recombination
Neoplasms
5 Citations

Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity

Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T. D., Feb 6 2018, In : Cell Reports. 22, 6, p. 1365-1373 9 p.

Research output: Contribution to journalArticle

Carnitine O-Palmitoyltransferase
Lysine
Phosphopyruvate Hydratase
Isotope Labeling
Mutation

Chk1 inhibitor SCH 900776 enhances the antitumor activity of MLN4924 on pancreatic cancer

Li, J. A., Song, C., Rong, Y., Kuang, T., Wang, D., Xu, X., Yuan, J., Luo, K., Qin, B., Nowsheen, S., Lou, Z. & Lou, W., Jan 1 2018, (Accepted/In press) In : Cell Cycle. p. 1-9 9 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
DNA Damage
Cullin Proteins
Proteasome Endopeptidase Complex
Enzymes
2 Citations

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

Yu, J., Qin, B., Moyer, A. M., Nowsheen, S., Liu, T., Qin, S., Zhuang, Y., Liu, D., Lu, S. W., Kalari, K. R., Visscher, D. W., Copland, J. A. III., McLaughlin, S. A., Moreno Aspitia, A., Northfelt, D. W., Gray, R. J., Lou, Z., Suman, V. J., Weinshilboum, R. M., Boughey, J. C. & 2 othersGoetz, M. P. & Wang, L. M., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2376-2388 13 p.

Research output: Contribution to journalArticle

decitabine
Triple Negative Breast Neoplasms
Methyltransferases
DNA
Biomarkers

Erratum to: Topoisomerase IIα controls the decatenation checkpoint (Nature Cell Biology, (2009), 11, 2, (204-210), 10.1038/ncb1828)

Luo, K., Yuan, J., Chen, J. & Lou, Z., Jan 1 2018, (Accepted/In press) In : Nature Cell Biology.

Research output: Contribution to journalArticle

Cell Biology
Molecular Biology