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Collaborations and top research areas from the last five years
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Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteins
Zhang, Y. Y., Gendron, T. T. F., Gendron, T. D., Zhang, K. & Zhang, Y.
National Institute of Neurological Disorders and Stroke
7/15/21 → 6/30/24
Project: Research project
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Understanding the Mechanisms of TDP-43 Function
Zhang, Y. & Fryer, J. D.
National Institute of Neurological Disorders and Stroke
2/15/13 → 1/31/16
Project: Research project
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HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases
Calliari, A., Daughrity, L. M., Albagli, E. A., Castellanos Otero, P., Yue, M., Jansen-West, K., Islam, N. N., Caulfield, T., Rawlinson, B., DeTure, M., Cook, C., Graff-Radford, N. R., Day, G. S., Boeve, B. F., Knopman, D. S., Petersen, R. C., Josephs, K. A., Oskarsson, B., Gitler, A. D., Dickson, D. W., & 5 others , Dec 2024, In: Molecular neurodegeneration. 19, 1, 29.Research output: Contribution to journal › Letter › peer-review
Open Access -
Mis-spliced transcripts generate de novo proteins in TDP-43–related Als/FTD
Seddighi, S., Qi, Y. A., Brown, A. L., Wilkins, O. G., Bereda, C., Belair, C., Zhang, Y. J., Prudencio, M., Keuss, M. J., Khandeshi, A., Pickles, S., Kargbo-Hill, S. E., Hawrot, J., Ramos, D. M., Yuan, H., Roberts, J., Sacramento, E. K., Shah, S. I., Nalls, M. A., Colón-Mercado, J. M., & 31 others , 2024, In: Science translational medicine. 16, 734, eadg7162.Research output: Contribution to journal › Article › peer-review
Open Access -
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia
Marks, J. D., Ayuso, V. E., Carlomagno, Y., Yue, M., Todd, T. W., Hao, Y., Li, Z., McEachin, Z. T., Shantaraman, A., Duong, D. M., Daughrity, L. M., Jansen-West, K., Shao, W., Calliari, A., Bejarano, J. G., DeTure, M., Rawlinson, B., Casey, M. C., Lilley, M. T., Donahue, M. H., & 16 others , Jan 17 2024, In: Science translational medicine. 16, 730, eadf9735.Research output: Contribution to journal › Article › peer-review
Open Access -
Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
Neel, D. V., Basu, H., Gunner, G., Bergstresser, M. D., Giadone, R. M., Chung, H., Miao, R., Chou, V., Brody, E., Jiang, X., Lee, E., Watts, M. E., Marques, C., Held, A., Wainger, B., Lagier-Tourenne, C., Zhang, Y. J., Petrucelli, L., Young-Pearse, T. L., Chen-Plotkin, A. S., & 3 others , Apr 19 2023, In: Neuron. 111, 8, p. 1222-1240.e9Research output: Contribution to journal › Article › peer-review
Open Access -
Inflammasome-Mediated Neuronal-Microglial Crosstalk: a Therapeutic Substrate for the Familial C9orf72 Variant of Frontotemporal Dementia/Amyotrophic Lateral Sclerosis
Trageser, K. J., Yang, E. J., Smith, C., Iban-Arias, R., Oguchi, T., Sebastian-Valverde, M., Iqbal, U. H., Wu, H., Estill, M., Al Rahim, M., Raval, U., Herman, F. J., Zhang, Y. J., Petrucelli, L. & Pasinetti, G. M., Jul 2023, In: Molecular Neurobiology. 60, 7, p. 4004-4016 13 p.Research output: Contribution to journal › Article › peer-review
Open Access