Yongjie Zhang, PhD

  • 4016 Citations
  • 27 Scopus h-Index

Research output per year

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Understanding the Mechanisms of TDP-43 Function

Fryer, J. D. & Zhang, Y.


Project: Research project

Research Output

  • 4016 Citations
  • 27 Scopus h-Index
  • 36 Article
  • 2 Comment/debate
  • 2 Review article

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

Todd, T. W., McEachin, Z. T., Chew, J., Burch, A. R., Jansen-West, K., Tong, J., Yue, M., Song, Y., Castanedes-Casey, M., Kurti, A., Dunmore, J. H., Fryer, J. D., Zhang, Y. J., San Millan, B., Teijeira Bautista, S., Arias, M., Dickson, D., Gendron, T. F., Sobrido, M. J., Disney, M. D. & 3 others, Bassell, G. J., Rossoll, W. & Petrucelli, L., May 5 2020, In : Cell reports. 31, 5, 107616.

Research output: Contribution to journalArticle

Open Access
  • 1 Scopus citations

    Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72

    Zhu, Q., Jiang, J., Gendron, T. F., McAlonis-Downes, M., Jiang, L., Taylor, A., Diaz Garcia, S., Ghosh Dastidar, S., Rodriguez, M. J., King, P., Zhang, Y., La Spada, A. R., Xu, H., Petrucelli, L., Ravits, J., Da Cruz, S., Lagier-Tourenne, C. & Cleveland, D. W., May 1 2020, In : Nature Neuroscience. 23, 5, p. 615-624 10 p.

    Research output: Contribution to journalArticle

  • 6 Scopus citations

    Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

    Chew, J., Cook, C., Gendron, T. F., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. J. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 9.

    Research output: Contribution to journalArticle

  • 14 Scopus citations
    Open Access
  • Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity

    Zhang, Y. J., Guo, L., Gonzales, P. K., Gendron, T. F., Wu, Y., Jansen-West, K., O’Raw, A. D., Pickles, S. R., Prudencio, M., Carlomagno, Y., Gachechiladze, M. A., Ludwig, C., Tian, R., Chew, J., DeTure, M., Lin, W. L., Tong, J., Daughrity, L. M., Yue, M., Song, Y. & 15 others, Andersen, J. W., Castanedes-Casey, M., Kurti, A., Datta, A., Antognetti, G., McCampbell, A., Rademakers, R., Oskarsson, B., Dickson, D. W., Kampmann, M., Ward, M. E., Fryer, J. D., Link, C. D., Shorter, J. & Petrucelli, L., Feb 15 2019, In : Science. 363, 6428, eaav2606.

    Research output: Contribution to journalArticle

  • 31 Scopus citations