William Stephen Brimijoin, PhD

  • 6752 Citations
  • 43 Scopus h-Index
1970 …2019
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  • 2 Similar Profiles
Acetylcholinesterase Medicine & Life Sciences
Butyrylcholinesterase Medicine & Life Sciences
Axonal Transport Medicine & Life Sciences
Cocaine Medicine & Life Sciences
Hydrolases Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Cholinesterases Medicine & Life Sciences
Sciatic Nerve Medicine & Life Sciences

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Projects 1978 2018

Cocaine-Related Disorders
Hydrolases
Cocaine
Genes
Telecommunications
Axonal Transport
Peripheral Nervous System Diseases
Organelles
Protein Transport
Surface Antigens

PERIPHERAL NEUROPATHY RESEARCH

Low, P. A., Poduslo, J. F., Windebank, A. J., Schmid, H. H. O., Dyck, P. J., Brimijoin, W. S. & Schmid, H. H. O.

National Institutes of Health

4/1/783/31/98

Project: Research project

Diabetic Neuropathies
Sural Nerve
Blood-Nerve Barrier
Peripheral Nervous System Diseases
Microvessels

Research Output 1970 2019

Amyloid Plaques
Acetylcholinesterase
Conformations
Alzheimer Disease
Amyloid
6 Citations (Scopus)

17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior

Steyn, F. J., Ngo, S. T., Chen, V. P., Bailey-Downs, L. C., Xie, T. Y., Ghadami, M., Brimijoin, W. S., Freeman, W. M., Rubinstein, M., Low, M. J. & Stout, M. B., Feb 1 2018, In : Aging Cell. 17, 1, e12703.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Arcuate Nucleus of Hypothalamus
Feeding Behavior
Weight Loss
Estradiol
23 Citations (Scopus)

Cholinesterases and the fine line between poison and remedy

Pope, C. N. & Brimijoin, W. S., Jan 1 2018, (Accepted/In press) In : Biochemical Pharmacology.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Poisons
Cholinesterases
Acetylcholinesterase
Cholinesterase Inhibitors

Erratum to: Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity (Scientific Reports, (2017), 7, 1, (10419), 10.1038/s41598-017-10571-z)

Larrimore, K. E., Kazan, I. C., Kannan, L., Kendle, R. P., Jamal, T., Barcus, M., Bolia, A., Brimijoin, W. S., Zhan, C. G., Ozkan, S. B. & Mor, T. S., Dec 1 2018, In : Scientific Reports. 8, 1, 17223.

Research output: Contribution to journalComment/debate

Butyrylcholinesterase
Cholinesterases
Hydrolases
Cocaine

Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway

Seo, S., Mathison, A., Grzenda, A., Podratz, J., Calvo, E., Brimijoin, W. S., Windebank, A. J., Iovanna, J., Lomberk, G. & Urrutia, R., Dec 1 2018, In : Scientific Reports. 8, 1, 15077.

Research output: Contribution to journalArticle

Nerve Growth Factor
Cyclic AMP-Dependent Protein Kinases
Cell Differentiation
Heterochromatin
PC12 Cells