William Stephen Brimijoin, PhD

Professor

  • 6515 Citations
  • 42 h-Index
1970 …2018
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Acetylcholinesterase Medicine & Life Sciences
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Hydrolases Medicine & Life Sciences
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Enzymes Medicine & Life Sciences
Cholinesterases Medicine & Life Sciences

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Projects 1978 2018

Cocaine-Related Disorders
Hydrolases
Cocaine
Genes
Telecommunications

AXONAL TRANSPORT IN PERIPHERAL NERVE DISEASE

Brimijoin, W. S.

National Institutes of Health

4/1/823/31/95

Project: Research projectResearch Project

Axonal Transport
Peripheral Nervous System Diseases
Organelles
Protein Transport
Surface Antigens

PERIPHERAL NEUROPATHY RESEARCH

Low, P. A., Poduslo, J. F., Windebank, A. J., Schmid, H. H. O., Dyck, P. J., Brimijoin, W. S. & Schmid, H. H. O.

National Institutes of Health

4/1/783/31/98

Project: Research projectResearch Program Projects

Diabetic Neuropathies
Sural Nerve
Blood-Nerve Barrier
Peripheral Nervous System Diseases
Microvessels

Research Output 1970 2018

2 Citations

17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior

Steyn, F. J., Ngo, S. T., Chen, V. P., Bailey-Downs, L. C., Xie, T. Y., Ghadami, M., Brimijoin, W. S., Freeman, W. M., Rubinstein, M., Low, M. J. & Stout, M. B., Feb 1 2018, In : Aging Cell. 17, 1, e12703.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Arcuate Nucleus of Hypothalamus
Feeding Behavior
Weight Loss
Estradiol
5 Citations

Cholinesterases and the fine line between poison and remedy

Pope, C. N. & Brimijoin, W. S., Jan 1 2018, (Accepted/In press) In : Biochemical Pharmacology.

Research output: Contribution to journalArticle

Butyrylcholinesterase
Poisons
Cholinesterases
Acetylcholinesterase
Cholinesterase Inhibitors

Erratum to: Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity (Scientific Reports, (2017), 7, 1, (10419), 10.1038/s41598-017-10571-z)

Larrimore, K. E., Kazan, I. C., Kannan, L., Kendle, R. P., Jamal, T., Barcus, M., Bolia, A., Brimijoin, W. S., Zhan, C. G., Ozkan, S. B. & Mor, T. S., Dec 1 2018, In : Scientific Reports. 8, 1, 17223.

Research output: Contribution to journalComment/debate

Butyrylcholinesterase
Cholinesterases
Hydrolases
Cocaine

Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway

Seo, S., Mathison, A., Grzenda, A., Podratz, J., Calvo, E., Brimijoin, W. S., Windebank, A. J., Iovanna, J., Lomberk, G. & Urrutia, R., Dec 1 2018, In : Scientific Reports. 8, 1, 15077.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Cell Differentiation
Nerve Growth Factor
Heterochromatin
PC12 Cells
1 Citations

Treating cocaine addiction, obesity, and emotional disorders by viral gene transfer of butyrylcholinesterase

Brimijoin, W. S., Gao, Y., Geng, L. & Chen, V. P., Feb 27 2018, In : Frontiers in Pharmacology. 9, FEB, 112.

Research output: Contribution to journalShort survey

Butyrylcholinesterase
Cocaine-Related Disorders
Viral Genes
Ghrelin
Obesity