Tufia C Haddad, MD

  • 1122 Citations
  • 17 Scopus h-Index
19972019
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Research Output 1997 2019

  • 1122 Citations
  • 17 Scopus h-Index
  • 38 Article
  • 7 Review article
  • 1 Chapter
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Article
2018
2 Citations (Scopus)

Adherence to guidelines for breast surveillance in breast cancer survivors

Ruddy, K. J., Sangaralingham, L., Freedman, R. A., Mougalian, S., Neuman, H., Greenberg, C., Jemal, A., Duma, N., Haddad, T. C., Lemaine, V., Ghosh, K., Hieken, T. J., Hunt, K., Vachon, C. M., Gross, C. & Shah, N. D., May 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 5, p. 526-534 9 p.

Research output: Contribution to journalArticle

Guideline Adherence
Survivors
Breast
Breast Neoplasms
Mammography
3 Citations (Scopus)
Survivors
Breast Neoplasms
Health
Education
Information Storage and Retrieval
1 Citation (Scopus)

Aurora-A overexpression is linked to development of aggressive teratomas derived from human iPS cells

Ohmine, S., Salisbury, J. L., Ingle, J., Pettinato, G., Haddox, C. L., Haddad, T. C., Galanis, E., Ikeda, Y. H. & D'Assoro, A., Apr 1 2018, In : Oncology Reports. 39, 4, p. 1725-1730 6 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Teratoma
Chromosomal Instability
Centrosome
Aurora Kinase A
9 Citations (Scopus)

Function, shoulder motion, pain, and lymphedema in breast cancer with and without axillary web syndrome: An 18-month follow-up

Koehler, L. A., Hunter, D. W., Blaes, A. H. & Haddad, T. C., Jun 1 2018, In : Physical Therapy. 98, 6, p. 518-527 10 p.

Research output: Contribution to journalArticle

Shoulder Pain
Articular Range of Motion
Breast Neoplasms
Lymphedema
Breast Cancer Lymphedema
9 Citations (Scopus)

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

Leontovich, A. A., Jalalirad, M., Salisbury, J. L., Mills, L., Haddox, C., Schroeder, M., Tuma, A., Guicciardi, M. E., Zammataro, L., Gambino, M. W., Amato, A., Di Leonardo, A., McCubrey, J., Lange, C. A., Liu, M. C., Haddad, T. C., Goetz, M. P., Boughey, J. C., Sarkaria, J. N., Wang, L. M. & 3 others, Ingle, J. N., Galanis, E. & D'Assoro, A., Sep 4 2018, In : Breast Cancer Research. 20, 1, 105.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
Phenotype
2017
9 Citations (Scopus)

A phase II study of combined ridaforolimus and dalotuzumab compared with exemestane in patients with estrogen receptor-positive breast cancer

Baselga, J., Morales, S. M., Awada, A., Blum, J. L., Tan, A. R., Ewertz, M., Cortes, J., Moy, B., Ruddy, K. J., Haddad, T. C., Ciruelos, E. M., Vuylsteke, P., Ebbinghaus, S., Im, E., Eaton, L., Pathiraja, K., Gause, C., Mauro, D., Jones, M. B. & Rugo, H. S., Mar 21 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-10 10 p.

Research output: Contribution to journalArticle

exemestane
Estrogen Receptors
Breast Neoplasms
Stomatitis
Incidence
27 Citations (Scopus)

A phase II trial of neoadjuvant MK-2206, an AKT inhibitor, with anastrozole in clinical stage II or III PIK3CA-mutant ER-positive and HER2-negative breast cancer

Ma, C. X., Suman, V. J., Goetz, M. P., Northfelt, D. W., Burkard, M. E., Ademuyiwa, F., Naughton, M., Margenthaler, J., Aft, R., Gray, R., Tevaarwerk, A., Wilke, L., Haddad, T. C., Moynihan, T., Loprinzi, C. L., Hieken, T. J., Barnell, E. K., Skidmore, Z. L., Feng, Y. Y., Krysiak, K. & 14 others, Hoog, J., Guo, Z., Nehring, L., Wisinski, K. B., Mardis, E., Hagemann, I. S., Vij, K., Sanati, S., Al-Kateb, H., Griffith, O. L., Griffith, M., Doyle, L., Erlichman, C. & Ellis, M. J., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 6823-6832 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Estrogens
Phosphorylation
Goserelin
Apoptosis
14 Citations (Scopus)

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

Haddad, T. C., Qin, R., Lupu, R., Satele, D., Eadens, M., Goetz, M. P., Erlichman, C. & Molina, J. R., Jun 1 2017, In : Cancer Chemotherapy and Pharmacology. 79, 6, p. 1221-1227 7 p.

Research output: Contribution to journalArticle

Paclitaxel
Tumors
Neoplasms
Clinical Trials, Phase I
Maximum Tolerated Dose

Breast Cancer Survivorship Care Variations Between Adjuvant Chemotherapy Regimens

Leal, A. D., Van Houten, H., Sangaralingham, L., Freedman, R. A., Jemal, A., Neuman, H. B., Haddad, T. C., Mutter, R., Keegan, T. H. M., Mougalian, S. S., Loprinzi, C. L., Gross, C. P., Shah, N. D. & Ruddy, K. J., 2017, (Accepted/In press) In : Clinical Breast Cancer.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Cyclophosphamide
Doxorubicin
Survival Rate
docetaxel
24 Citations (Scopus)

First-in-human phase I Study of the tamoxifen metabolite Z-endoxifen in women with endocrine-refractory metastatic breast cancer

Goetz, M. P., Suman, V. J., Reid, J. M., Northfelt, D. W., Mahr, M. A., Ralya, A. T., Kuffel, M., Visscher, S. A., Kipp, B. R., Liu, M. C., Hawse, J. R., Ames, M. M., Ingle Buhrow, J. N., Safgren, S. L., McGovern, R. M., Black, J., Dockter, T., Haddad, T. C., Erlichman, C., Adjei, A. & 7 others, Collins, D., Streicher, H., Chalmers, Z. R., Frampton, G., Hawse, J. R., Doroshow, J. H. & Collins, J. M., Oct 20 2017, In : Journal of Clinical Oncology. 35, 30, p. 3391-3400 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Breast Neoplasms
Maximum Tolerated Dose
Mutation
Cytochrome P-450 CYP2D6
9 Citations (Scopus)

Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells

Opyrchal, M., Malgorzata, G., Salisbury, J. L., Goetz, M. P., Suman, V. J., Degnim, A. C., McCubrey, J., Haddad, T. C., Iankov, I., Kurokawa, C. B., Shumacher, N., Ingle, J. N., Galanis, E. & D'Assoro, A., 2017, In : Oncotarget. 8, 53, p. 91803-91816 14 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplastic Stem Cells
Aurora Kinase A
Drug Resistance
Epithelial-Mesenchymal Transition
2 Citations (Scopus)

Phase I trial to evaluate the addition of alisertib to fulvestrant in women with endocrine-resistant, ER+ metastatic breast cancer

Haddad, T. C., D'Assoro, A., Suman, V. J., Opyrchal, M., Peethambaram, P., Liu, M. C., Goetz, M. P. & Ingle, J. N., Dec 30 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-9 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Aurora Kinase A
Aromatase Inhibitors
fulvestrant
MLN 8237
2016
131 Citations (Scopus)

Adaptive randomization of neratinib in early breast cancer

the I-SPY 2 Investigators, Jul 7 2016, In : New England Journal of Medicine. 375, 1, p. 11-22 12 p.

Research output: Contribution to journalArticle

Random Allocation
Breast Neoplasms
Biomarkers
Hormones
Neoadjuvant Therapy
205 Citations (Scopus)

Adaptive randomization of veliparib-carboplatin treatment in breast cancer

the I-SPY 2 Investigators, Jul 7 2016, In : New England Journal of Medicine. 375, 1, p. 23-34 12 p.

Research output: Contribution to journalArticle

Carboplatin
Random Allocation
Breast Neoplasms
Biomarkers
Triple Negative Breast Neoplasms
35 Citations (Scopus)

Aurora-A kinase as a promising therapeutic target in cancer

D'Assoro, A., Haddad, T. C. & Galanis, E., 2016, In : Frontiers in Oncology. 5, JAN, 295.

Research output: Contribution to journalArticle

Aurora Kinase A
Neoplasms
Therapeutics
Aurora Kinases
Chromosomal Instability
4 Citations (Scopus)

Mindfulness-based cancer recovery in survivors recovering from chemotherapy and radiation

Blaes, A. H., Fenner, D., Bachanova, V., Torkelson, C., Geller, M., Haddad, T. C., Shanley, R. & Kreitzer, M. J., Aug 1 2016, In : Journal of Community and Supportive Oncology. 14, 8, p. 351-358 8 p.

Research output: Contribution to journalArticle

Mindfulness
Survivors
Radiation
Drug Therapy
Neoplasms
1 Citation (Scopus)
Urticaria
Paraneoplastic Syndromes
Breast Neoplasms
Neoplasms
Neurologic Manifestations
2015
4 Citations (Scopus)

Angiotensin Converting Enzyme Inhibitors (ACEI) and doxorubicin pharmacokinetics in women receiving adjuvant breast cancer treatment

Blaes, A., Duprez, D., Defor, T., Shanley, R., Beckwith, H., Haddad, T. C., Potter, D., Yee, D., Sanghavi, K. & Jacobson, P., Dec 30 2015, In : SpringerPlus. 4, 1, 32.

Research output: Contribution to journalArticle

Angiotensin-Converting Enzyme Inhibitors
Doxorubicin
Pharmacokinetics
Enalapril
Breast Neoplasms
17 Citations (Scopus)

Clinicopathologic features of breast cancers that develop in women with previous benign breast disease

Visscher, D. W., Frost, M. H., Hartmann, L. C., Frank, R. D., Vierkant, R. A., Mccullough, A. E., Winham, S. J., Vachon, C. M., Ghosh, K., Brandt, K. R., Farrell, A. M., Tarabishy, Y., Hieken, T. J., Haddad, T. C., Kraft, R. A., Radisky, D. C. & Degnim, A. C., 2015, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Breast Diseases
Breast Neoplasms
Lymph Nodes
Estrogen Receptors
Hyperplasia
18 Citations (Scopus)

Landscape of Neoadjuvant Therapy for Breast Cancer

Haddad, T. C. & Goetz, M. P., May 1 2015, In : Annals of Surgical Oncology. 22, 5, p. 1408-1415 8 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Breast Neoplasms
Therapeutics
Drug Therapy
Tumor Burden
19 Citations (Scopus)

Movement, function, pain, and postoperative edema in axillary web syndrome

Koehler, L. A., Blaes, A. H., Haddad, T. C., Hunter, D. W., Hirsch, A. T. & Ludewig, P. M., Oct 1 2015, In : Physical Therapy. 95, 10, p. 1345-1353 9 p.

Research output: Contribution to journalArticle

Postoperative Pain
Edema
Breast Neoplasms
Articular Range of Motion
Body Mass Index
45 Citations (Scopus)

The neoadjuvant model is still the future for drug development in breast cancer

De Michele, A., Yee, D., Berry, D. A., Albain, K. S., Benz, C. C., Boughey, J. C., Buxton, M., Chia, S. K., Chien, A. J., Chui, S. Y., Clark, A., Edmiston, K., Elias, A. D., Forero-Torres, A., Haddad, T. C., Haley, B., Haluska, P., Hylton, N. M., Isaacs, C., Kaplan, H. & 22 others, Korde, L., Leyland-Jones, B., Liu, M. C., Melisko, M., Minton, S. E., Moulder, S. L., Nanda, R., Olopade, O. I., Paoloni, M., Park, J. W., Parker, B. A., Perlmutter, J., Petricoin, E. F., Rugo, H., Symmans, F., Tripathy, D., Van't Veer, L. J., Viscusi, R. K., Wallace, A., Wolf, D., Yau, C. & Esserman, L. J., Jul 1 2015, In : Clinical Cancer Research. 21, 13, p. 2911-2915 5 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Meta-Analysis
Clinical Trials
Pharmaceutical Preparations
Disease-Free Survival
2014
13 Citations (Scopus)

Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells

Opyrchal, M., Salisbury, J. L., Zhang, S., McCubrey, J., Hawse, J. R., Goetz, M. P., Lomberk, G. A., Haddad, T. C., Degnim, A. C., Lange, C., Ingle, J. N., Galanis, E. & D'Assoro, A., May 9 2014, In : PLoS One. 9, 5, e96995.

Research output: Contribution to journalArticle

Aurora Kinase A
Estrogen Receptor alpha
breast neoplasms
phosphotransferases (kinases)
Phosphotransferases
14 Citations (Scopus)

Characterizing axillary web syndrome: Ultrasonographic efficacy

Koehler, L. A., Hunter, D. W., Haddad, T. C., Blaes, A. H., Hirsch, A. T. & Ludewig, P. M., Dec 1 2014, In : Lymphology. 47, 4, p. 156-163 8 p.

Research output: Contribution to journalArticle

Subcutaneous Tissue
Lymphatic Abnormalities
Skin
Fibrin
Transducers
4 Citations (Scopus)

New-onset heart failure in association with severe hypertension during trastuzumab therapy

Herrmann, J., Herrmann, S. & Haddad, T. C., Dec 1 2014, In : Mayo Clinic Proceedings. 89, 12, p. 1734-1739 6 p.

Research output: Contribution to journalArticle

Heart Failure
Hypertension
Precipitating Factors
Therapeutics
Breast Neoplasms
2012
11 Citations (Scopus)

Adaptive trials in the neoadjuvant setting: A model to safely tailor care while accelerating drug development

Yee, D., Haddad, T. C., Albain, K., Barker, A., Benz, C., Boughey, J. C., Buxton, M., Chien, A. J., DeMichele, A., Dilts, D., Elias, A., Haluska, P., Hogarth, M., Hu, A., Hytlon, N., Kaplan, H. G., Kelloff, G. G., Khan, Q., Lang, J., Leyland-Jones, B. & 18 others, Liu, M. C., Nanda, R., Northfelt, D. W., Olopade, O. I., Park, J., Parker, B., Parkinson, D., Pearson-White, S., Perlmutter, J., Pusztai, L., Symmans, F., Rugo, H., Tripathy, D., Wallace, A., Wholley, D., Van't Veer, L., Berry, D. A. & Esserman, L., Dec 20 2012, In : Journal of Clinical Oncology. 30, 36, p. 4584-4586 3 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Patient satisfaction with physician discussions of treatment impact on fertility, menopause and sexual health among pre-menopausal women with cancer

Scanlon, M., Blaes, A., Geller, M., Majhail, N. S., Lindgren, B. & Haddad, T. C., 2012, In : Journal of Cancer. 3, 1, p. 217-225 9 p.

Research output: Contribution to journalArticle

Reproductive Health
Menopause
Patient Satisfaction
Fertility
Physicians
2011
35 Citations (Scopus)

Hexapeptide libraries for enhanced protein PTM identification and relative abundance profiling in whole human saliva

Bandhakavi, S., Van Riper, S. K., Tawfik, P. N., Stone, M. D., Haddad, T. C., Rhodus, N. L., Carlis, J. V. & Griffin, T. J., Mar 4 2011, In : Journal of Proteome Research. 10, 3, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

Pulse time modulation
Saliva
Libraries
Workflow
Proteins
16 Citations (Scopus)

Nonpharmacologic complementary therapies in symptom management for breast cancer survivors

Blaes, A. H., Kreitzer, M. J., Torkelson, C. & Haddad, T. C., Jun 2011, In : Seminars in Oncology. 38, 3, p. 394-402 9 p.

Research output: Contribution to journalArticle

Complementary Therapies
Survivors
Breast Neoplasms
Quality of Life
Physicians
31 Citations (Scopus)

Smoking and quality of life among female survivors of breast, colorectal and endometrial cancers in a prospective cohort study

Jang, S., Prizment, A., Haddad, T. C., Robien, K. & Lazovich, D., Jun 2011, In : Journal of Cancer Survivorship. 5, 2, p. 115-122 8 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Survivors
Colorectal Neoplasms
Cohort Studies
Smoking
2010
21 Citations (Scopus)

Conflict of interest in economic analyses of aromatase inhibitors in breast cancer: A systematic review

Jang, S., Chae, Y. K., Haddad, T. C. & Majhail, N. S., Jun 2010, In : Breast Cancer Research and Treatment. 121, 2, p. 273-279 7 p.

Research output: Contribution to journalArticle

Conflict of Interest
Aromatase Inhibitors
Economics
Breast Neoplasms
Pharmaceutical Preparations
2008
13 Citations (Scopus)

Of mice and (Wo)men: Is this any way to test a new drug?

Haddad, T. C. & Yee, D., Feb 20 2008, In : Journal of Clinical Oncology. 26, 6, p. 830-832 3 p.

Research output: Contribution to journalArticle

Hormone-Dependent Neoplasms
Xenograft Model Antitumor Assays
ErbB-2 Receptor
Ki-67 Antigen
Quinazolines
2007
25 Citations (Scopus)

Pregnancy and thrombophilia

Patnaik, M. M., Haddad, T. C. & Morton, C. T., Jul 2007, In : Expert Review of Cardiovascular Therapy. 5, 4, p. 753-765 13 p.

Research output: Contribution to journalArticle

Thrombophilia
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Anticoagulants
2006
207 Citations (Scopus)

Chemotherapy-induced thrombosis

Haddad, T. C. & Greeno, E. W., 2006, In : Thrombosis Research. 118, 5, p. 555-568 14 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
Thrombosis
Drug Therapy
Neoplasms
Second Primary Neoplasms
9 Citations (Scopus)

Targeting the insulin-like growth factor axis as a cancer therapy

Haddad, T. C. & Yee, D., Feb 2006, In : Future Oncology. 2, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

Somatomedins
Neoplasms
Therapeutics
IGF Type 1 Receptor
Clinical Trials, Phase I
1999
14 Citations (Scopus)
Pregnancy-Associated Plasma Protein-A
Somatomedins
Conditioned Culture Medium
Fibroblasts
Affinity Chromatography
1997
18 Citations (Scopus)

Evaluation of continuous infusion suramin in metastatic breast cancer: Impact on plasma levels of insulin-like growth factors (IGFs) and IGF- binding proteins

Lawrence, J. B., Conover, C. A., Haddad, T. C., Ingle, J. N., Reid, J. M., Ames, M. M., Suman, V. J., Marks, R. S., Erlichman, C. & Hartmann, L. C., Oct 1997, In : Clinical Cancer Research. 3, 10, p. 1713-1720 8 p.

Research output: Contribution to journalArticle

Suramin
Insulin-Like Growth Factor Binding Proteins
Somatomedins
Breast Neoplasms
Insulin-Like Growth Factor I
22 Citations (Scopus)
Insulin Receptor Substrate Proteins
Somatomedins
Interleukin-4
Insulin-Like Growth Factor I
Insulin