Tufia C Haddad, MD

  • 1239 Citations
  • 17 Scopus h-Index
19972020

Research output per year

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Research Output

2020

Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor

Ingle, J. N., Cairns, J., Suman, V. J., Shepherd, L. E., Fasching, P. A., Hoskin, T. L., Singh, R. J., Desta, Z., Kalari, K. R., Ellis, M. J., Goss, P. E., Chen, B. E., Volz, B., Barman, P., Carlson, E. E., Haddad, T., Goetz, M. P., Goodnature, B., Cuellar, M. E., Walters, M. A. & 4 others, Correia, C., Kaufmann, S. H., Weinshilboum, R. M. & Wang, L., Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2986-2996 11 p.

Research output: Contribution to journalArticle

Open Access

Evaluation of germline genetic testing criteria in a hospital-based series of women with breast cancer

Yadav, S., Hu, C., Hart, S. N., Boddicker, N., Polley, E. C., Na, J., Gnanaolivu, R., Lee, K. Y., Lindstrom, T., Armasu, S., Fitz-Gibbon, P., Ghosh, K., Stan, D. L., Pruthi, S., Neal, L., Sandhu, N. P., Rhodes, D. J., Klassen, C., Peethambaram, P. P., Haddad, T. C. & 7 others, Olson, J. E., Hoskin, T. L., Goetz, M. P., Domchek, S. M., Boughey, J. C., Ruddy, K. J. & Couch, F. J., May 1 2020, In : Journal of Clinical Oncology. 38, 13, p. 1409-1418 10 p.

Research output: Contribution to journalArticle

Open Access

Follow-up Care for Breast Cancer Survivors

Ruddy, K. J., Herrin, J., Sangaralingham, L., Freedman, R. A., Jemal, A., Haddad, T. C., Allen, S. V., Hieken, T., Boughey, J. C., Ganz, P. A., Havyer, R. D. & Shah, N. D., Jan 1 2020, In : Journal of the National Cancer Institute. 112, 1, p. 111-113 3 p.

Research output: Contribution to journalArticle

TBCRC 032 IB/II Multicenter Study: Molecular Insights to AR Antagonist and PI3K Inhibitor Efficacy in Patients with AR+ Metastatic Triple-Negative Breast Cancer

Translational Breast Cancer Research Consortium, May 1 2020, In : Clinical Cancer Research. 26, 9, p. 2111-2123 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Utilization of Cardiac Surveillance Tests in Survivors of Breast Cancer and Lymphoma after Anthracycline-Based Chemotherapy

Ruddy, K. J., Sangaralingham, L. R., Van Houten, H., Nowsheen, S., Sandhu, N. P., Moslehi, J., Neuman, H., Jemal, A., Haddad, T. C., Blaes, A. H., Villarraga, H. R., Thompson, C., Shah, N. D. & Herrmann, J., Mar 1 2020, In : Circulation: Cardiovascular Quality and Outcomes. e005984.

Research output: Contribution to journalArticle

2019

Axillary web syndrome following breast cancer surgery: Symptoms, complications, and management strategies

Koehler, L. A., Haddad, T. C., Hunter, D. W. & Tuttle, T. M., Jan 1 2019, In : Breast Cancer: Targets and Therapy. 11, p. 13-19 7 p.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations

Implementation of artificial intelligence (AI) for lung cancer clinical trial matching in a tertiary cancer center

Leventakos, K., Helgeson, J., Mansfield, A. S., Deering, E., Schwecke, A., Adjei, A., Molina, J., Hocum, C., Halfdanarson, T., Marks, R., Parikh, K., Pomerleau, K., Coverdill, S., Rammage, M. & Haddad, T., Apr 1 2019, In : Annals of oncology : official journal of the European Society for Medical Oncology. 30, p. ii74

Research output: Contribution to journalArticle

Open Access

Integrated rehabilitation for breast cancer survivors

Cheville, A. L., McLaughlin, S. A., Haddad, T. C., Lyons, K. D., Newman, R. & Ruddy, K. J., Feb 1 2019, In : American Journal of Physical Medicine and Rehabilitation. 98, 2, p. 154-164 11 p.

Research output: Contribution to journalReview article

5 Scopus citations
2018

Adherence to guidelines for breast surveillance in breast cancer survivors

Ruddy, K. J., Sangaralingham, L., Freedman, R. A., Mougalian, S., Neuman, H., Greenberg, C., Jemal, A., Duma, N., Haddad, T. C., Lemaine, V., Ghosh, K., Hieken, T. J., Hunt, K., Vachon, C. M., Gross, C. & Shah, N. D., May 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 5, p. 526-534 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
4 Scopus citations

Aurora-A overexpression is linked to development of aggressive teratomas derived from human iPS cells

Ohmine, S., Salisbury, J. L., Ingle, J., Pettinato, G., Haddox, C. L., Haddad, T., Galanis, E., Ikeda, Y. & D'Assoro, A. B., Apr 2018, In : Oncology reports. 39, 4, p. 1725-1730 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Breast Cancer Survivorship Care Variations Between Adjuvant Chemotherapy Regimens

Leal, A. D., Van Houten, H., Sangaralingham, L., Freedman, R. A., Jemal, A., Neuman, H. B., Haddad, T. C., Mutter, R. W., Keegan, T. H. M., Mougalian, S. S., Loprinzi, C. L., Gross, C. P., Shah, N. & Ruddy, K. J., Aug 2018, In : Clinical breast cancer. 18, 4, p. e513-e520

Research output: Contribution to journalArticle

1 Scopus citations

Cardiovascular Concerns in BRCA1 and BRCA2 Mutation Carriers

Gast, K. C., Viscuse, P. V., Nowsheen, S., Haddad, T. C., Mutter, R., Wahner Hendrickson, A. E., Couch, F. J. & Ruddy, K. J., Feb 1 2018, In : Current Treatment Options in Cardiovascular Medicine. 20, 2, 18.

Research output: Contribution to journalReview article

3 Scopus citations

Function, shoulder motion, pain, and lymphedema in breast cancer with and without axillary web syndrome: An 18-month follow-up

Koehler, L. A., Hunter, D. W., Blaes, A. H. & Haddad, T. C., Jun 1 2018, In : Physical Therapy. 98, 6, p. 518-527 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

Leontovich, A. A., Jalalirad, M., Salisbury, J. L., Mills, L., Haddox, C., Schroeder, M., Tuma, A., Guicciardi, M. E., Zammataro, L., Gambino, M. W., Amato, A., Di Leonardo, A., McCubrey, J., Lange, C. A., Liu, M., Haddad, T., Goetz, M., Boughey, J., Sarkaria, J., Wang, L. & 3 others, Ingle, J. N., Galanis, E. & D'Assoro, A. B., Sep 4 2018, In : Breast Cancer Research. 20, 1, 105.

Research output: Contribution to journalArticle

12 Scopus citations

Phase I dose expansion data for M6620 (formerly VX-970), a first-in-class ATR inhibitor, combined with gemcitabine (Gem) in patients (pts) with advanced non-small cell lung cancer (NSCLC)

Plummer, R., Cook, N., Arkenau, T., Melear, J., Redfern, C., Spira, A. I., Chung, K., Haddad, T., Ramalingam, S. S., Wesolowski, R., Dean, E., Goddemeier, T., Falk, M. & Shapiro, G., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii519

Research output: Contribution to journalArticle

Open Access

Phase i trial to evaluate the addition of alisertib to fulvestrant in women with endocrine-resistant, ER+ metastatic breast cancer

Haddad, T. C., D’Assoro, A., Suman, V., Opyrchal, M., Peethambaram, P., Liu, M. C., Goetz, M. P. & Ingle, J. N., Dec 30 2018, In : Breast Cancer Research and Treatment. 168, 3, p. 639-647 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Updates in the Evaluation and Management of Breast Cancer

O'Sullivan, C. C., Loprinzi, C. L. & Haddad, T. C., Jun 1 2018, In : Mayo Clinic Proceedings. 93, 6, p. 794-807 14 p.

Research output: Contribution to journalReview article

11 Scopus citations
2017

A phase II study of combined ridaforolimus and dalotuzumab compared with exemestane in patients with estrogen receptor-positive breast cancer

Baselga, J., Morales, S. M., Awada, A., Blum, J. L., Tan, A. R., Ewertz, M., Cortes, J., Moy, B., Ruddy, K. J., Haddad, T. C., Ciruelos, E. M., Vuylsteke, P., Ebbinghaus, S., Im, E., Eaton, L., Pathiraja, K., Gause, C., Mauro, D., Jones, M. B. & Rugo, H. S., Mar 21 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-10 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

A phase II trial of neoadjuvant MK-2206, an AKT inhibitor, with anastrozole in clinical stage II or III PIK3CA-mutant ER-positive and HER2-negative breast cancer

Ma, C. X., Suman, V., Goetz, M. P., Northfelt, D., Burkard, M. E., Ademuyiwa, F., Naughton, M., Margenthaler, J., Aft, R., Gray, R., Tevaarwerk, A., Wilke, L., Haddad, T., Moynihan, T., Loprinzi, C., Hieken, T., Barnell, E. K., Skidmore, Z. L., Feng, Y. Y., Krysiak, K. & 14 others, Hoog, J., Guo, Z., Nehring, L., Wisinski, K. B., Mardis, E., Hagemann, I. S., Vij, K., Sanati, S., Al-Kateb, H., Griffith, O. L., Griffith, M., Doyle, L., Erlichman, C. & Ellis, M. J., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 6823-6832 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

Haddad, T., Qin, R., Lupu, R., Satele, D., Eadens, M., Goetz, M. P., Erlichman, C. & Molina, J., Jun 1 2017, In : Cancer Chemotherapy and Pharmacology. 79, 6, p. 1221-1227 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

First-in-human phase I Study of the tamoxifen metabolite Z-endoxifen in women with endocrine-refractory metastatic breast cancer

Goetz, M. P., Suman, V. J., Reid, J. M., Northfelt, D. W., Mahr, M. A., Ralya, A. T., Kuffel, M., Visscher, S. A., Kipp, B. R., Liu, M. C., Hawse, J. R., Ames, M. M., Ingle Buhrow, J. N., Safgren, S. L., McGovern, R. M., Black, J., Dockter, T., Haddad, T., Erlichman, C., Adjei, A. A. & 7 others, Collins, D., Streicher, H., Chalmers, Z. R., Frampton, G., Hawse, J. R., Doroshow, J. H. & Collins, J. M., Oct 20 2017, In : Journal of Clinical Oncology. 35, 30, p. 3391-3400 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Impact of treatment regimen on acute care use during and after adjuvant chemotherapy for early-stage breast cancer

Ruddy, K. J., Van Houten, H. K., Sangaralingham, L. R., Freedman, R. A., Thompson, C. A., Hashmi, S. K., Jemal, A., Haddad, T. C., Mougalian, S., Herrin, J., Gross, C. & Shah, N. D., Aug 1 2017, In : Breast Cancer Research and Treatment. 164, 3, p. 515-525 11 p.

Research output: Contribution to journalReview article

5 Scopus citations

Incidence, Diagnosis, and Treatment of Cardiac Toxicity From Trastuzumab in Patients With Breast Cancer

Nowsheen, S., Viscuse, P. V., O’Sullivan, C. C., Sandhu, N. P., Haddad, T. C., Blaes, A., Klemp, J., Nhola, L., Herrmann, J. & Ruddy, K. J., Sep 1 2017, In : Current Breast Cancer Reports. 9, 3, p. 173-182 10 p.

Research output: Contribution to journalReview article

4 Scopus citations

Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells

Opyrchal, M., Malgorzata, G., Salisbury, J. L., Goetz, M. P., Suman, V., Degnim, A., McCubrey, J., Haddad, T., Iankov, I., Kurokawa, C. B., Shumacher, N., Ingle, J. N., Galanis, E. & D'Assoro, A. B., 2017, In : Oncotarget. 8, 53, p. 91803-91816 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Novel approaches to support breast cancer survivorship care models

Gast, K. C., Allen, S., Ruddy, K. J. & Haddad, T. C., Dec 1 2017, In : Breast. 36, p. 1-13 13 p.

Research output: Contribution to journalReview article

5 Scopus citations
2016

Adaptive randomization of neratinib in early breast cancer

the I-SPY 2 Investigators, Jul 7 2016, In : New England Journal of Medicine. 375, 1, p. 11-22 12 p.

Research output: Contribution to journalArticle

149 Scopus citations

Adaptive randomization of veliparib-carboplatin treatment in breast cancer

the I-SPY 2 Investigators, Jul 7 2016, In : New England Journal of Medicine. 375, 1, p. 23-34 12 p.

Research output: Contribution to journalArticle

229 Scopus citations

Aurora-A kinase as a promising therapeutic target in cancer

D'Assoro, A. B., Haddad, T. & Galanis, E., 2016, In : Frontiers in Oncology. 5, JAN, 295.

Research output: Contribution to journalArticle

42 Scopus citations

Mindfulness-based cancer recovery in survivors recovering from chemotherapy and radiation

Blaes, A. H., Fenner, D., Bachanova, V., Torkelson, C., Geller, M., Haddad, T. C., Shanley, R. & Kreitzer, M. J., Aug 1 2016, In : Journal of Community and Supportive Oncology. 14, 8, p. 351-358 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations
2015

Angiotensin Converting Enzyme Inhibitors (ACEI) and doxorubicin pharmacokinetics in women receiving adjuvant breast cancer treatment

Blaes, A., Duprez, D., Defor, T., Shanley, R., Beckwith, H., Haddad, T. C., Potter, D., Yee, D., Sanghavi, K. & Jacobson, P., Dec 30 2015, In : SpringerPlus. 4, 1, 32.

Research output: Contribution to journalArticle

4 Scopus citations

Clinicopathologic features of breast cancers that develop in women with previous benign breast disease

Visscher, D. W., Frost, M. H., Hartmann, L. C., Frank, R. D., Vierkant, R. A., Mccullough, A. E., Winham, S. J., Vachon, C. M., Ghosh, K., Brandt, K. R., Farrell, A. M., Tarabishy, Y., Hieken, T. J., Haddad, T. C., Kraft, R. A., Radisky, D. C. & Degnim, A. C., 2015, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

20 Scopus citations

Landscape of Neoadjuvant Therapy for Breast Cancer

Haddad, T. C. & Goetz, M. P., May 1 2015, In : Annals of Surgical Oncology. 22, 5, p. 1408-1415 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Movement, function, pain, and postoperative edema in axillary web syndrome

Koehler, L. A., Blaes, A. H., Haddad, T. C., Hunter, D. W., Hirsch, A. T. & Ludewig, P. M., Oct 2015, In : Physical Therapy. 95, 10, p. 1345-1353 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

The neoadjuvant model is still the future for drug development in breast cancer

De Michele, A., Yee, D., Berry, D. A., Albain, K. S., Benz, C. C., Boughey, J., Buxton, M., Chia, S. K., Chien, A. J., Chui, S. Y., Clark, A., Edmiston, K., Elias, A. D., Forero-Torres, A., Haddad, T. C., Haley, B., Haluska, P., Hylton, N. M., Isaacs, C., Kaplan, H. & 22 others, Korde, L., Leyland-Jones, B., Liu, M. C., Melisko, M., Minton, S. E., Moulder, S. L., Nanda, R., Olopade, O. I., Paoloni, M., Park, J. W., Parker, B. A., Perlmutter, J., Petricoin, E. F., Rugo, H., Symmans, F., Tripathy, D., Van't Veer, L. J., Viscusi, R. K., Wallace, A., Wolf, D., Yau, C. & Esserman, L. J., Jul 1 2015, In : Clinical Cancer Research. 21, 13, p. 2911-2915 5 p.

Research output: Contribution to journalArticle

46 Scopus citations
2014

Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells

Opyrchal, M., Salisbury, J. L., Zhang, S., McCubrey, J., Hawse, J., Goetz, M. P., Lomberk, G. A., Haddad, T., Degnim, A., Lange, C., Ingle, J. N., Galanis, E. & D'Assoro, A. B., May 9 2014, In : PloS one. 9, 5, e96995.

Research output: Contribution to journalArticle

14 Scopus citations

Characterizing axillary web syndrome: Ultrasonographic efficacy

Koehler, L. A., Hunter, D. W., Haddad, T. C., Blaes, A. H., Hirsch, A. T. & Ludewig, P. M., Dec 1 2014, In : Lymphology. 47, 4, p. 156-163 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
5 Scopus citations
2012

Adaptive trials in the neoadjuvant setting: A model to safely tailor care while accelerating drug development

Yee, D., Haddad, T., Albain, K., Barker, A., Benz, C., Boughey, J., Buxton, M., Chien, A. J., DeMichele, A., Dilts, D., Elias, A., Haluska, P., Hogarth, M., Hu, A., Hytlon, N., Kaplan, H. G., Kelloff, G. G., Khan, Q., Lang, J., Leyland-Jones, B. & 18 others, Liu, M., Nanda, R., Northfelt, D., Olopade, O. I., Park, J., Parker, B., Parkinson, D., Pearson-White, S., Perlmutter, J., Pusztai, L., Symmans, F., Rugo, H., Tripathy, D., Wallace, A., Wholley, D., Van't Veer, L., Berry, D. A. & Esserman, L., Dec 20 2012, In : Journal of Clinical Oncology. 30, 36, p. 4584-4586 3 p.

Research output: Contribution to journalLetter

11 Scopus citations

Patient satisfaction with physician discussions of treatment impact on fertility, menopause and sexual health among pre-menopausal women with cancer

Scanlon, M., Blaes, A., Geller, M., Majhail, N. S., Lindgren, B. & Haddad, T., 2012, In : Journal of Cancer. 3, 1, p. 217-225 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
2011

Basic principles of antineoplastic therapies

Haddad, T. & Yee, D., Dec 1 2011, Breast Surgical Techniques and Interdisciplinary Management. Springer New York, p. 707-715 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hexapeptide libraries for enhanced protein PTM identification and relative abundance profiling in whole human saliva

Bandhakavi, S., Van Riper, S. K., Tawfik, P. N., Stone, M. D., Haddad, T., Rhodus, N. L., Carlis, J. V. & Griffin, T. J., Mar 4 2011, In : Journal of Proteome Research. 10, 3, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Nonpharmacologic complementary therapies in symptom management for breast cancer survivors

Blaes, A. H., Kreitzer, M. J., Torkelson, C. & Haddad, T., Jun 1 2011, In : Seminars in oncology. 38, 3, p. 394-402 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Smoking and quality of life among female survivors of breast, colorectal and endometrial cancers in a prospective cohort study

Jang, S., Prizment, A., Haddad, T., Robien, K. & Lazovich, D. A., Jun 1 2011, In : Journal of Cancer Survivorship. 5, 2, p. 115-122 8 p.

Research output: Contribution to journalArticle

32 Scopus citations
2010

Conflict of interest in economic analyses of aromatase inhibitors in breast cancer: A systematic review

Jang, S., Chae, Y. K., Haddad, T. & Majhail, N. S., Jun 1 2010, In : Breast Cancer Research and Treatment. 121, 2, p. 273-279 7 p.

Research output: Contribution to journalReview article

21 Scopus citations
2008

Of mice and (Wo)men: Is this any way to test a new drug?

Haddad, T. C. & Yee, D., Feb 20 2008, In : Journal of Clinical Oncology. 26, 6, p. 830-832 3 p.

Research output: Contribution to journalEditorial

13 Scopus citations
2007

Pregnancy and thrombophilia

Patnaik, M. M., Haddad, T. & Morton, C. T., Jul 1 2007, In : Expert Review of Cardiovascular Therapy. 5, 4, p. 753-765 13 p.

Research output: Contribution to journalReview article

25 Scopus citations
2006

Chemotherapy-induced thrombosis

Haddad, T. C. & Greeno, E. W., Sep 25 2006, In : Thrombosis research. 118, 5, p. 555-568 14 p.

Research output: Contribution to journalReview article

220 Scopus citations

Targeting the insulin-like growth factor axis as a cancer therapy

Haddad, T. & Yee, D., Feb 1 2006, In : Future Oncology. 2, 1, p. 101-110 10 p.

Research output: Contribution to journalReview article

9 Scopus citations