Thomas Caulfield, PhD

Associate Consultant, Associate Consultant

  • 2080 Citations
  • 22 Scopus h-Index
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  • 1 Similar Profiles
Proteins Medicine & Life Sciences
Waldenstrom Macroglobulinemia Medicine & Life Sciences
Molecular Dynamics Simulation Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Exome Medicine & Life Sciences
Informatics Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences

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Research Output 2006 2019

  • 2080 Citations
  • 22 Scopus h-Index
  • 50 Article
  • 3 Review article
  • 1 Chapter
  • 1 Letter
4 Citations (Scopus)

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

Research output: Contribution to journalReview article

Apolipoproteins E
Alzheimer Disease
Apolipoprotein E4

Design and Evaluation of PEGylated Liposomal Formulation of a Novel Multikinase Inhibitor for Enhanced Chemosensitivity and Inhibition of Metastatic Pancreatic Ductal Adenocarcinoma

Madamsetty, V. S., Pal, K., Dutta, S. K., Wang, E., Thompson, J. R., Banerjee, R. K., Caulfield, T. R., Mody, K., Yen, Y., Mukhopadhyay, D. & Huang, H. S., Oct 16 2019, In : Bioconjugate Chemistry. 30, 10, p. 2703-2713 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases

Development of multi-drug loaded PEGylated nanodiamonds to inhibit tumor growth and metastasis in genetically engineered mouse models of pancreatic cancer

Madamsetty, V. S., Pal, K., Keshavan, S., Caulfield, T. R., Dutta, S. K., Wang, E., Fadeel, B. & Mukhopadhyay, D., Dec 7 2019, In : Nanoscale. 11, 45, p. 22006-22018 13 p.

Research output: Contribution to journalArticle

Drug delivery
2 Citations (Scopus)

Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin

Cohen, I., Coban, M., Shahar, A., Sankaran, B., Hockla, A., Lacham, S., Caulfield, T., Radisky, E. S. & Papo, N., Jan 1 2019, In : Journal of Biological Chemistry. 294, 13, p. 5105-5120 16 p.

Research output: Contribution to journalArticle

Serine Proteinase Inhibitors
Human Engineering
Peptide Hydrolases

Genomic observations of a rare/pathogenic SMAD3 variant in Loeys–Dietz syndrome 3 confirmed by protein informatics and structural investigations

Richter, J. E., Samreen, A., Vadlamudi, C., Helmi, H., Mohammad, A. N., Wierenga, K., Hines, S., Atwal, P. S. & Caulfield, T., May 1 2019, In : Medicina (Lithuania). 55, 5, 137.

Research output: Contribution to journalArticle

Open Access
Marfan Syndrome