Thomas Caulfield, PhD

Associate Consultant, Associate Consultant

  • 2002 Citations
  • 22 Scopus h-Index
20062019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Thomas Caulfield is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Proteins Medicine & Life Sciences
Waldenstrom Macroglobulinemia Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Molecular Dynamics Simulation Medicine & Life Sciences
Exome Medicine & Life Sciences
Informatics Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2006 2019

  • 2002 Citations
  • 22 Scopus h-Index
  • 48 Article
  • 3 Review article
  • 1 Chapter
  • 1 Letter

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T., Liu, C-C. & Bu, G. D., Sep 1 2019, In : Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

Research output: Contribution to journalReview article

Apolipoproteins E
Alzheimer Disease
Apolipoprotein E4
Alleles
Pathology

Design and Evaluation of PEGylated Liposomal Formulation of a Novel Multikinase Inhibitor for Enhanced Chemosensitivity and Inhibition of Metastatic Pancreatic Ductal Adenocarcinoma

Madamsetty, V. S., Pal, K., Dutta, S. K., Wang, E., Thompson, J. R., Banerjee, R. K., Caulfield, T. R., Mody, K., Yen, Y., Mukhopadhyay, D. & Huang, H. S., Oct 16 2019, In : Bioconjugate Chemistry. 30, 10, p. 2703-2713 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
gemcitabine
Adenocarcinoma
Chemotherapy
Protein-Tyrosine Kinases
1 Citation (Scopus)

Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin

Cohen, I., Coban, M., Shahar, A., Sankaran, B., Hockla, A., Lacham, S., Caulfield, T., Radisky, E. S. & Papo, N., Jan 1 2019, In : Journal of Biological Chemistry. 294, 13, p. 5105-5120 16 p.

Research output: Contribution to journalArticle

Proteolysis
Serine Proteinase Inhibitors
Human Engineering
Disulfides
Peptide Hydrolases

Genomic observations of a rare/pathogenic SMAD3 variant in Loeys–Dietz syndrome 3 confirmed by protein informatics and structural investigations

Richter, J. E., Samreen, A., Vadlamudi, C., Helmi, H., Mohammad, A. N., Wierenga, K., Hines, S., Atwal, P. S. & Caulfield, T., May 1 2019, In : Medicina (Lithuania). 55, 5, 137.

Research output: Contribution to journalArticle

Open Access
Informatics
Virulence
Uvula
Marfan Syndrome
Proteins
2 Citations (Scopus)

Integrative data fusion for comprehensive assessment of a novel CHEK2 variant using combined genomics, imaging, and functional-structural assessments via protein informatics

Hines, S. L., Mohammad, A. N., Jackson, J., Macklin, S. & Caulfield, T., Jan 1 2019, In : Molecular Omics. 15, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

Informatics
Data fusion
Genomics
Imaging techniques
Proteins