Projects per year
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- 2 Similar Profiles
Cholinergic Receptors
Medicine & Life Sciences
Nicotinic Receptors
Medicine & Life Sciences
Congenital Myasthenic Syndromes
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Binding Sites
Medicine & Life Sciences
Acetylcholine
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Cysteine Loop Ligand-Gated Ion Channel Receptors
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1985 2020
Mechanism of calcium potentiation of alpha7 nicotinic receptors
7/1/16 → 6/30/20
Project: Research project
Nicotinic Receptors
Calcium
Divalent Cations
Cognition Disorders
Drug Design
Cysteine Loop Ligand-Gated Ion Channel Receptors
Neurotransmitter Receptor
Binding Sites
Pharmaceutical Preparations
Anti-Anxiety Agents
Cholinergic Receptors
Neurotransmitter Receptor
Congenital Myasthenic Syndromes
Neurotransmitter Agents
Ion Channels
Cholinergic Receptors
Ion Channels
Neurotransmitter Agents
Receptors, Serotonin, 5-HT3
Nicotinic Receptors
NATIONAL BIOMEDICAL NMR RESOURCE AT MADISON
Prendergast, F. G., Sine, S. M., Nmrfam, [. V., Gellman, S. H., Handelsman, J. O., Gesteland, R. A. Y., [No Value], H. H., Nealey, P. F., Palmer, A. G., De Pablo, J. J., Tang, P. E. I., Berg, J., Escalante, J., Vickery, L., Zhou, M., Malecki, M., Fry, C., Dejesus, O., Pflueger, F., Parkin, K., Varian, V., Gracz, H., Kleps, R., Berg, J., Escalante, J., Zhou, M., Malecki, M., Parkin, K., Varian, V., Gracz, H., Kleps, R., Vickery, L., Downs, D. M., Pflueger, F., Fillingame, R., Fry, C., Klein, B., Laurence, J., Perczel, A., Griffith, B., Blackwell, H. E., Rankin, S., Gellman, S. H., Frey, P. D., Sigel, R., Jeffries, T. W., van Doren, S., Mujeeb, A., Wand, J., Varani, G., Murphy, W., Walters, K., Oswald, R., Matthews, B. A., Skrynnikov, N., Matsuo, H., Anderson, M., Vierstra, R., Andes, A., Huang, R. C., Ahlquist, P. G., Lan, Q. U. E., Kent, S. B. H., Smith, J. L., Gourse, R. L., Walters, K. J., Komives, E. A., Ntambi, J. A., Murphy, J. R., Lindroth, A. N. N., Rouho, A., Johnson, D. G., [No Value], B. G., Vugmeyster, L., Roucho, A., Schram, V., Halkides, C., Nicholson, L., Angeletti, R., Bolton, P., McKay, D., James, T., Schroeder, C., Erlichman, J., Tsai, M., Nair, H. K., Charles, S., Roberts, J., Shi-Jiang, L., Almo, S., Tsang, P., Feigon, J., Klein, S., Arus, C., Clancy, P., Young, R., Cheng, T., Ulrich, E., Girvin, M. E., Kiessling, L., Satterlee, J., Chobanian, M., Harsy, S., Honggao, Y., Russu, I., Agris, P., Fillingame, R., Gunasekaran, S., Weber, D. J., Wand, A., Record, M. T., Wemmer, D., Bleam, W., Stone, M., Swaminathan, S., Donohue, T., Westler, W., Nmrfam Staff, [. V., Raines, R., Dzakula, Z., Mooberry, E., Anderson, L., Triplett, E., Gilboe, D., Ralph, J., Elfarra, A., Liao, X., Lightfoot, E., Cleland, W. W., Lemaster, D., De Luca, H., Schleucher, J., Downs, D. M., Chien, H., van Doren, S., Frey, P. A., Volkman, B., [No Value], B. G., Paaren, H., Anderson, M., Reddy, V., Deluca, P., Dejesus, O. T., Tran, C., Reed, G., Ruoho, A. E., [No Value], J. H., Bax, A. D., Markley, J., Escalante, J., Mosher, D. F., Butcher, S., Loria, J., Roucho, A., Mosher, D. F., Thorson, J. S., Vugmeyster, L., [No Value], B. G., Cavagnero, S., Sem, D., Halkides, C., McKay, D., Cheng, T., Gunasekaran, S., Ralph, J., De Luca, H., Anderson, M., Schram, V., Nicholson, L., Angeletti, R., Schroeder, C., Erlichman, J., Tsai, M., Nair, H. K., Charles, S., Roberts, J., Shi-Jiang, L., Almo, S., Tsang, P., Feigon, J., Klein, S., Arus, C., Clancy, P., Girvin, M. E., Kiessling, L., Chobanian, M., Harsy, S., Honggao, Y., Russu, I., Agris, P., Fillingame, R., Weber, D. J., Wand, A., Record, M. T., Wemmer, D., Bleam, W., Stone, M., Swaminathan, S., Donohue, T., Nmrfam Staff, [. V., Dzakula, Z., Mooberry, E., Anderson, L., Liao, X., Lightfoot, E., Cleland, W. W., Lemaster, D., Schleucher, J., Downs, D. M., Chien, H., van Doren, S., Frey, P. A., Volkman, B., [No Value], B. G., Paaren, H., Reddy, V., Dejesus, O. T., Tran, C., Reed, G., Ruoho, A. E., [No Value], J. H., Bax, A. D., Zuiderweg, E., Dratz, E., Nair, H., Agard, D., Puglisi, R., Nmrfam, [. V., Dakula, D., Young, R., Bashir, M., Nikolau, B., Miziorko, H., Pardi, A., Abildgaard, F., Stockman, B., Kasper, C., Metzler, D., Serpersu, E., Dumesic, J., Anthonsen, H., Baldwin, R., Filligname, R., Morrissey, M., Gellman, S. H., Guiles, R., Weiss, M. A., Hutchinson, C., Royer, C., Fitzpatrick, P., Menon, A., Neuhaus, F., Steele, J., Goldman, I., Handelsman, J. O., Burnette, R., Redwine, D., Stone, C., Gesteland, R. A. Y., Escalante, J., Northrop, D., Schroeder, C., Banfield, J., Fesik, S., Gauthier, J., Rule, G., Helmke, P., Bushweller, J. H., Walker, J., [No Value], H. H., Dratz, E., Feigon, J., Sundquist, W., Dewerd, L., Ganther, H., Mosher, D. F., Kenealy, W., McGee, W., Harsy, S., Sussman, M., Gmeiner, W., Nealey, P. F., Hemmi, H., Honggao, Y., Palmer, A. G., Dzakula, R., Bashir, M., Agris, P., Reed, J., De Pablo, J. J., Bullerjahn, G., Pariza, M., Fillingame, R., Chambliss, G., Hinck, A., Margolis, F., Johnson, M., Driscoll, J., Qureshi, N., Pyle, A. M., Tang, P. E. I., Burgess, R., Phillips, G. N., Berg, J., Malecki, M., Escalante, J., Vickery, L., Zhou, M., Sidhu, A., Butcher, S., Fry, C., Cavagnero, S., Khorasanizadeh, S., Stauffacher, C. V., Pflueger, F., Fillingame, R., Alexandrescu, A., Sem, D., Parkin, K., Varian, V., Gracz, H., Lutsenko, S., Kleps, R., Phillips, G. N., Berg, J., Malecki, M., Escalante, J., Liao, X., Zhou, M., Sidhu, A., Khorasanizadeh, S., Stauffacher, C. V., Alexandrescu, A., Reed, G., Parkin, K., Varian, V., Gracz, H., Lutsenko, S., Kleps, R., Vickery, L., Garfinkel, M., Downs, D. M., [No Value], B. G., Pflueger, F., Fillingame, R., Sem, D., Fry, C., De Luca, H., Cavagnero, S., Ralph, J., Cleland, W. W., Butcher, S., Zuiderweg, E., Loria, J., Santalucia, J., Klein, B., Laurence, J., Perczel, A., Griffith, B., Blackwell, H. E., Rankin, S., Gellman, S. H., Hellekant, G., van Doren, S., Frey, P. D., Gizachew, D., Sigel, R., Kwang, H., Jeffries, T. W., Mujeeb, A., Wand, J., Varani, G., Bushweller, J. H., Roucho, A., Murphy, W., Walters, K., Mosher, D. F., Oswald, R., Thorson, J. S., Matthews, B. A., Skrynnikov, N., Matsuo, H., Kalodimos, C., Anderson, M., Kiessling, L., B Craig, L., Veglia, G., Assadi-Porter, F., Vierstra, R., Andes, A., Rajagopal, P., Huang, R. C., Dunham, S., Walters, K., Vugmeyster, L., Parson, W., Ahlquist, P. G., Keck, J., Sorgen, P., Craig, E., Weibel, D. B., Lan, Q. U. E., Ensign, J., Escalante, J., Frihart, C., Dmitriev, O., Mari, F., Rivera, E., Kent, S. B. H., van Doren, S., Denu, J., Smith, J. L., Gourse, R. L., Roucho, A., Loria, J., Cook, M., Walters, K. J., Deluca, H., Xie, J., Ansari, A., Mosher, D. F., Andes, D., Dixon, J., [No Value], B. G., Michael, C., Zimei, B., Attie, A., Marino, J. P., Wildman, K. A. H., Whittaker, J., Komives, E. A., Klein, B. S., Schroeder, F., Fry, C., Keutsch, F., Ntambi, J. A., Abraham, B., Yawen, B., Murphy, J. R., Ralph, J., Degrado, W., Lindroth, A. N. N., Wadsworth, K., Thorson, J. S., Hamann, M., Cavagnero, S., Bugni, T., Vugmeyster, L., Rouho, A., Wang, S., Sem, D., Johnson, D. G., Rayment, I., Raines, R., Westler, W., Nmrfam Staff, Nmrfam & Klein, B.
7/1/85 → 2/28/15
Project: Research project
Spectrometers
Biochemistry
Magnetic resonance
Macromolecules
Nuclear magnetic resonance
Research Output 1974 2019
1
Citation
(Scopus)
Potentiation of a neuronal nicotinic receptor via pseudo-agonist site
Mazzaferro, S., Bermudez, I. & Sine, S. M., Jan 1 2019, (Accepted/In press) In : Cellular and Molecular Life Sciences.Research output: Contribution to journal › Article
Nicotinic Receptors
Mutation
Pharmaceutical Preparations
Pharmacology
Drug Design
Structural basis for α-bungarotoxin insensitivity of neuronal nicotinic acetylcholine receptors
Sine, S. M., Strikwerda, J. R. & Mazzaferro, S., Jan 1 2019, In : Neuropharmacology. 107660.Research output: Contribution to journal › Article
Bungarotoxins
Nicotinic Receptors
Muscles
neuronal bungarotoxin
Sequence Alignment
1
Citation
(Scopus)
Full and partial agonists evoke distinct structural changes in opening the muscle acetylcholine receptor channel
Mukhtasimova, N. & Sine, S. M., May 1 2018, In : Journal of General Physiology. 150, 5, p. 713-729 17 p.Research output: Contribution to journal › Article
Cholinergic Receptors
Cysteine
Muscles
Cholinergic Agonists
Choline
1
Citation
(Scopus)
Mutations causing congenital myasthenia reveal principal coupling pathway in the acetylcholine receptor ε-subunit
Shen, X. M., Brengman, J. M., Shen, S., Durmus, H., Preethish-Kumar, V., Yuceyar, N., Vengalil, S., Nalini, A., Deymeer, F., Sine, S. M. & Engel, A. G., Jan 25 2018, In : JCI insight. 3, 2Research output: Contribution to journal › Article
Open Access
Congenital Myasthenic Syndromes
Cholinergic Receptors
Mutation
Cysteine Loop Ligand-Gated Ion Channel Receptors
Muscles
14
Citations
(Scopus)
Nicotinic acetylcholine receptors at the single-channel level
Bouzat, C. & Sine, S. M., 2017, (Accepted/In press) In : British Journal of Pharmacology.Research output: Contribution to journal › Article
Nicotinic Receptors
Cholinergic Receptors
Patch-Clamp Techniques
Nobel Prize
Ligand-Gated Ion Channels