Steven G Younkin, MD, PhD

  • 41046 Citations
  • 88 Scopus h-Index
1974 …2019
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  • 4 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Amyloidogenic Proteins Medicine & Life Sciences
Brain Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Presenilin-1 Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences

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Projects 1975 2019

Genetic and Functional Analysis of Nested AD Risk Genes CTNNA3 and LRRTM3

Younkin, S. G., Ertekin-Taner, N. & Ertekin-Taner, N.

National Institutes of Health

8/1/155/31/17

Project: Research project

Genome-Wide Association Study
Genes
Costs and Cost Analysis
Alzheimer Disease
Exome
Neurodegenerative Diseases
Microglia
Phagocytosis
Ligands
Neurons

A system approach to targeting innate immunity in AD

Golde, T. E., Price, N., Golde, T. E., Ertekin-Taner, N., Ertekin-Taner, N., Golde, T. E. & Younkin, S. G.

National Institutes of Health

9/20/138/31/18

Project: Research project

Innate Immunity
Alzheimer Disease
Cognition
Genetic Loci
Gliosis
Genetic Markers
Genetic Load
Biomarkers
Alzheimer Disease
Genes

THE BIOLOGY OF ALZHEIMERS DISEASE IN TRANSGENIC MICE

Younkin, S. G., Carlson, G. A., Carlson, G. A., Chapman, P., Hyman, B. & Ashe, K.

National Institutes of Health

6/15/9911/30/04

Project: Research project

Amyloid
Mutation
Flavin-Adenine Dinucleotide
Transgenes
Transgenic Mice

Research Output 1974 2019

  • 41046 Citations
  • 88 Scopus h-Index
  • 252 Article
  • 1 Conference contribution
  • 1 Comment/debate

Evaluation of Associations of Alzheimer's Disease Risk Variants that Are Highly Expressed in Microglia with Neuropathological Outcome Measures

Sakae, N., Heckman, M. G., Vargas, E. R., Carrasquillo, M. M., Murray, M. E., Kasanuki, K., Ertekin-Taner, N., Younkin, S. G. & Dickson, D. W., Jan 1 2019, In : Journal of Alzheimer's Disease. 70, 3, p. 659-666 8 p.

Research output: Contribution to journalArticle

Microglia
Alzheimer Disease
Outcome Assessment (Health Care)
Cerebral Amyloid Angiopathy
Disease Susceptibility
29 Citations (Scopus)

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein
1 Citation (Scopus)

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Ebbert, M. T. W., Jensen, T. D., Jansen-West, K., Sens, J. P., Reddy, J. S., Ridge, P. G., Kauwe, J. S. K., Belzil, V., Pregent, L., Carrasquillo, M. M., Keene, D., Larson, E., Crane, P., Asmann, Y., Taner, N., Younkin, S. G., Ross, O. A., Rademakers, R. V., Petrucelli, L. & Fryer, J. D., May 20 2019, In : Genome biology. 20, 1, 97.

Research output: Contribution to journalArticle

Open Access
gene
Technology
Alzheimer disease
Genes
Alzheimer Disease
1 Citation (Scopus)

Association study between multiple system atrophy and TREM2 p.R47H

Ogaki, K., Heckman, M. G., Koga, S., Martens, Y. A., Labbé, C., Lorenzo-Betancor, O., Walton, R. L., Soto, A. I., Vargas, E. R., Fujioka, S., Uitti, R. J., Van Gerpen, J. A., Cheshire, W. P., Younkin, S. G., Wszolek, Z. K., Low, P. A., Singer, W., Bu, G. D., Dickson, D. W. & Ross, O. A., Aug 1 2018, In : Neurology: Genetics. 4, 4, e257.

Research output: Contribution to journalArticle

Multiple System Atrophy
Myeloid Cells
Alzheimer Disease
Odds Ratio
Sample Size
Neuroimaging
Hope
Alzheimer Disease
National Institute on Aging (U.S.)
National Institute of Neurological Disorders and Stroke