Stephen Maxted Ansell, MD, PhD

  • 22276 Citations
  • 80 Scopus h-Index
1976 …2020

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Article
2009

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes

Cerhan, J. R., Novak, A. J., Fredericksen, Z. S., Wang, A. H., Liebow, M., Call, T. G., Dogan, A., Witzig, T. E., Ansell, S. M., Habermann, T. M., Kay, N. E. & Slager, S. L., Jun 1 2009, In : British journal of haematology. 145, 5, p. 614-623 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Serum BLyS levels increase after rituximab as initial therapy in patients with follicular grade 1 non-Hodgkin lymphoma

Ansell, S. M., Novak, A. J., Ziesmer, S., Price-Troska, T., Laplant, B., Dillon, S. R. & Witzig, T. E., Feb 1 2009, In : American journal of hematology. 84, 2, p. 71-73 3 p.

Research output: Contribution to journalArticle

15 Scopus citations
2010

A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling

Hildebrand, J. M., Luo, Z., Manske, M. K., Price-Troska, T., Ziesmer, S. C., Lin, W., Hostager, B. S., Slager, S. L., Witzig, T. E., Ansell, S. M., Cerhan, J. R., Bishop, G. A. & Novak, A. J., Nov 22 2010, In : Journal of Experimental Medicine. 207, 12, p. 2569-2579 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma

Younes, A., Vose, J. M., Zelenetz, A. D., Smith, M. R., Burris, H. A., Ansell, S. M., Klein, J., Halpern, W., Miceli, R., Kumm, E., Fox, N. L. & Czuczman, M. S., Dec 7 2010, In : British journal of cancer. 103, 12, p. 1783-1787 5 p.

Research output: Contribution to journalArticle

100 Scopus citations

A phase II study of 153Sm-EDTMP and high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma

Dispenzieri, A., Wiseman, G. A., Lacy, M. Q., Hayman, S. R., Kumar, S. K., Buadi, F., Dingli, D., Laumann, K. M., Allred, J., Geyer, S. M., Litzow, M. R., Gastineau, D. A., Inwards, D. J., Micallef, I. N., Ansell, S. M., Porrata, L., Elliott, M. A., Johnston, P. B., Hogan, W. J. & Gertz, M. A., Jun 1 2010, In : American journal of hematology. 85, 6, p. 409-413 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma

Johnston, P. B., Inwards, D. J., Colgan, J. P., Laplant, B. R., Kabat, B. F., Habermann, T. M., Micallef, I. N., Porrata, L. F., Ansell, S. M., Reeder, C. B., Roy, V. & Witzig, T. E., May 1 2010, In : American journal of hematology. 85, 5, p. 320-324 5 p.

Research output: Contribution to journalArticle

173 Scopus citations

Autologous stem cell transplant for immunoglobulin light chain amyloidosis: A status report

Gertz, M. A., Lacy, M. Q., Dispenzieri, A., Hayman, S. R., Kumar, S. K., Dingli, D., Ansell, S. M., Gastineau, D. A., Inwards, D. J., Johnston, P. B., Litzow, M. R., Micallef, I. N. M., Porrata, L. F., Leung, N., Hogan, W. J. & Buadi, F. K., Dec 1 2010, In : Leukemia and Lymphoma. 51, 12, p. 2181-2187 7 p.

Research output: Contribution to journalArticle

77 Scopus citations
11 Scopus citations

Comparison of error rates in single-arm versus randomized phase II cancer clinical trials

Tang, H., Foster, N. R., Grothey, A., Ansell, S. M., Goldberg, R. M. & Sargent, D. J., Apr 10 2010, In : Journal of Clinical Oncology. 28, 11, p. 1936-1941 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma

Kelly, J. L., Novak, A. J., Fredericksen, Z. S., Liebow, M., Ansell, S. M., Dogan, A., Wang, A. H., Witzig, T. E., Call, T. G., Kay, N. E., Habermann, T. M., Slager, S. L. & Cerhan, J. R., Nov 1 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 11, p. 2847-2858 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

IgM multiple myeloma: Disease definition, prognosis, and differentiation from Waldenstrom's macroglobulinemia

Schuster, S. R., Rajkumar, S. V., Dispenzieri, A., Morice, W., Aspitia, A. M., Ansell, S., Kyle, R. & Mikhael, J., Nov 1 2010, In : American journal of hematology. 85, 11, p. 853-855 3 p.

Research output: Contribution to journalArticle

52 Scopus citations
15 Scopus citations
42 Scopus citations
24 Scopus citations

Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory waldenström macroglobulinemia

Ghobrial, I. M., Gertz, M., LaPlant, B., Camoriano, J., Hayman, S., Lacy, M., Chuma, S., Harris, B., Leduc, R., Rourke, M., Ansell, S. M., DeAngelo, D., Dispenzieri, A., Bergsagel, L., Reeder, C., Anderson, K. C., Richardson, P. G., Treon, S. P. & Witzig, T. E., Mar 10 2010, In : Journal of Clinical Oncology. 28, 8, p. 1408-1414 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Phase i trial of autologous hematopoietic SCT with escalating doses of topotecan combined with CY and carboplatin in patients with relapsed or persistent ovarian or primary peritoneal carcinoma

Litzow, M. R., Peethambaram, P. P., Safgren, S. L., Keeney, G. L., Ansell, S. M., Dispenzieri, A., Elliott, M. A., Gastineau, D. A., Gertz, M. A., Inwards, D. J., Lacy, M. Q., Micallef, I. N. M., Porrata, L. F., Lingle, W. L., Hartmann, L. C., Frost, M. H., Barrette, B. A., Long, H. J., Suman, V. J., Reid, J. M. & 2 others, Ames, M. M. & Kaufmann, S. H., Jan 1 2010, In : Bone Marrow Transplantation. 45, 3, p. 490-497 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Statin use and prognosis in patients with diffuse large B-cell lymphoma and follicular lymphoma in the rituximab era

Nowakowski, G. S., Maurer, M. J., Habermann, T. M., Ansell, S. M., Macon, W. R., Ristow, K. M., Allmer, C., Slager, S. L., Witzig, T. E. & Cerhan, J. R., Jan 20 2010, In : Journal of Clinical Oncology. 28, 3, p. 412-417 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Vitamin D insufficiency and prognosis in non-Hodgkin's lymphoma

Drake, M. T., Maurer, M. J., Link, B. K., Habermann, T. M., Ansell, S. M., Micallef, I. N., Kelly, J. L., Macon, W. R., Nowakowski, G. S., Inwards, D. J., Johnston, P. B., Singh, R. J., Allmer, C., Slager, S. L., Weiner, G. J., Witzig, T. E. & Cerhan, J. R., Sep 20 2010, In : Journal of Clinical Oncology. 28, 27, p. 4191-4198 8 p.

Research output: Contribution to journalArticle

160 Scopus citations
2011
4 Scopus citations

A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma

Witzig, T. E., Reeder, C. B., Laplant, B. R., Gupta, M., Johnston, P. B., Micallef, I. N., Porrata, L. F., Ansell, S. M., Colgan, J. P., Jacobsen, E. D., Ghobrial, I. M. & Habermann, T. M., Feb 2011, In : Leukemia. 25, 2, p. 341-347 7 p.

Research output: Contribution to journalArticle

238 Scopus citations
68 Scopus citations

Brentuximab vedotin: Delivering an antimitotic drug to activated lymphoma cells

Ansell, S. M., Jan 1 2011, In : Expert Opinion on Investigational Drugs. 20, 1, p. 99-105 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma

Burington, B., Yue, P., Shi, X., Advani, R., Lau, J. T., Tan, J., Stinson, S., Stinson, J., Januario, T., De Vos, S., Ansell, S., Forero-Torres, A., Fedorowicz, G., Yang, T. T. C., Elkins, K., Du, C., Mohan, S., Yu, N., Modrusan, Z., Seshagiri, S. & 9 others, Yu, S. F., Pandita, A., Koeppen, H., French, D., Polson, A. G., Offringa, R., Whiting, N., Ebens, A. & Dornan, D., Mar 16 2011, In : Science translational medicine. 3, 74, 74ra22.

Research output: Contribution to journalArticle

27 Scopus citations

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity

Elsawa, S. F., Novak, A. J., Ziesmer, S. C., Almada, L. L., Hodge, L. S., Grote, D. M., Witzig, T. E., Fernandez-Zapico, M. E. & Ansell, S. M., Nov 17 2011, In : Blood. 118, 20, p. 5540-5549 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Design and validity of a clinic-based case-control study on the molecular epidemiology of lymphoma

Cerhan, J. R., Fredericksen, Z. S., Wang, A. H., Habermann, T. M., Kay, N. E., Macon, W. R., Cunningham, J. M., Shanafelt, T. D., Ansell, S. M., Call, T. G., Witzig, T. E., Slager, S. L. & Liebow, M., Jun 13 2011, In : International Journal of Molecular Epidemiology and Genetics. 2, 2, p. 95-113 19 p.

Research output: Contribution to journalArticle

31 Scopus citations

Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing

Feldman, A. L., Dogan, A., Smith, D. I., Law, M. E., Ansell, S. M., Johnson, S. H., Porcher, J. C., Özsan, N., Wieben, E. D., Eckloff, B. W. & Vasmatzis, G., Jan 20 2011, In : Blood. 117, 3, p. 915-919 5 p.

Research output: Contribution to journalArticle

187 Scopus citations

Elevated serum free light chains are associated with event-free and overall survival in two independent cohorts of patients with diffuse large B-cell lymphoma

Maurer, M. J., Micallef, I. N. M., Cerhan, J. R., Katzmann, J. A., Link, B. K., Colgan, J. P., Habermann, T. M., Inwards, D. J., Markovic, S. N., Ansell, S. M., Porrata, L. F., Johnston, P. B., Nowakowski, G. S., Thompson, C. A., Gupta, M., Syrbu, S. I., Kurtin, P. J., Macon, W. R., Nikcevich, D. A. & Witzig, T. E., Apr 20 2011, In : Journal of Clinical Oncology. 29, 12, p. 1620-1626 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Elevated serum free light chains are associated with inferior event free and overall survival in Hodgkin lymphoma

Thompson, C. A., Maurer, M. J., Cerhan, J. R., Katzmann, J. A., Ansell, S. M., Habermann, T. M., Macon, W. R., Weiner, G. J., Link, B. K. & Witzig, T. E., Dec 1 2011, In : American journal of hematology. 86, 12, p. 998-1000 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Establishment and characterization of a novel Waldenström macroglobulinemia cell line, MWCL-1

Hodge, L. S., Novak, A. J., Grote, D. M., Braggio, E., Ketterling, R. P., Manske, M. K., Price Troska, T. L., Ziesmer, S. C., Fonseca, R., Witzig, T. E., Morice, W. G., Gertz, M. A. & Ansell, S. M., May 12 2011, In : Blood. 117, 19, p. e190-e197

Research output: Contribution to journalArticle

29 Scopus citations

GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment

Elsawa, S. F., Almada, L. L., Ziesmer, S. C., Novak, A. J., Witzig, T. E., Ansell, S. M. & Fernandez-Zapico, M. E., Jun 17 2011, In : Journal of Biological Chemistry. 286, 24, p. 21524-21534 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Jak/stat pathway in Waldenström's macroglobulinemia

Hodge, L. S. & Ansell, S. M., Feb 1 2011, In : Clinical Lymphoma, Myeloma and Leukemia. 11, 1, p. 112-114 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Lenalidomide can be safely combined with R-CHOP (R2CHOP) in the initial chemotherapy for aggressive B-cell lymphomas: Phase i study

Nowakowski, G. S., Laplant, B., Habermann, T. M., Rivera, C. E., MacOn, W. R., Inwards, D. J., Micallef, I. N., Johnston, P. B., Porrata, L. F., Ansell, S. M., Klebig, R. R., Reeder, C. B. & Witzig, T. E., Dec 1 2011, In : Leukemia. 25, 12, p. 1877-1881 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Low risk of symptomatic venous thromboembolic events during growth factor administration for PBSC mobilization

Naina, H. V., Pruthi, R. K., Inwards, D. J., Dingli, D., Litzow, M. R., Ansell, S. M., William, H. J., Dispenzieri, A., Buadi, F. K., Elliott, M. A., Gastineau, D. A., Gertz, M. A., Hayman, S. R., Johnston, P. B., Lacy, M. Q., Micallef, I. N., Porrata, L. F. & Kumar, S., Feb 1 2011, In : Bone Marrow Transplantation. 46, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

MicroRNA expression in tumor cells from Waldenstrom's macroglobulinemia reflects both their normal and malignant cell counterparts

Hodge, L. S., Elsawa, S. F., Grote, D. M., Price-Troska, T. L., Asmann, Y. W., Fonseca, R., Gertz, M. A., Witzig, T. E., Novak, A. J. & Ansell, S. M., Jun 1 2011, In : Blood cancer journal. 1, 6, e24.

Research output: Contribution to journalArticle

13 Scopus citations

Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas

Witzig, T. E., Tang, H., Micallef, I. N. M., Ansell, S. M., Link, B. K., Inwards, D. J., Porrata, L. F., Johnston, P. B., Colgan, J. P., Markovic, S. N., Nowakowski, G. S., Thompson, C. A., Allmer, C., Maurer, M. J., Gupta, M., Weiner, G., Hohl, R., Kurtin, P. J., Ding, H., Loegering, D. & 4 others, Schneider, P., Peterson, K., Habermann, T. M. & Kaufmann, S. H., Nov 3 2011, In : Blood. 118, 18, p. 4882-4889 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Predicting PBSC harvest failure using circulating CD34 levels: Developing target-based cutoff points for early intervention

Sinha, S., Gastineau, D., Micallef, I., Hogan, W., Ansell, S., Buadi, F., Dingli, D., Dispenzieri, A., Gertz, M., Greiner, C., Hayman, S., Inwards, D., Johnston, P., Lacy, M., Litzow, M., Porrata, L., Winters, J. L. & Kumar, S., Jul 1 2011, In : Bone Marrow Transplantation. 46, 7, p. 943-949 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Soluble IL-2Rα facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Manske, M. K., Witzig, T. E., Novak, A. J. & Ansell, S. M., Sep 8 2011, In : Blood. 118, 10, p. 2809-2820 12 p.

Research output: Contribution to journalArticle

72 Scopus citations

Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: A multicenter study of 204 skin biopsies

Wada, D. A., Law, M. E., Hsi, E. D., Dicaudo, D. J., Ma, L., Lim, M. S., De Souza, A., Comfere, N. I., Weenig, R. H., MacOn, W. R., Erickson, L. A., Özsan, N., Ansell, S. M., Dogan, A. & Feldman, A. L., Apr 1 2011, In : Modern Pathology. 24, 4, p. 596-605 10 p.

Research output: Contribution to journalArticle

101 Scopus citations

Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: A phase 2 study

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Inwards, D. J., Shah, K., Ziesmer, S. C., Feldman, A. L., Rao, R., Gupta, M., Erlichman, C. & Witzig, T. E., Apr 1 2011, In : The Lancet Oncology. 12, 4, p. 361-368 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

The absolute monocyte and lymphocyte prognostic score predicts survival and identifies high-risk patients in diffuse large-B-cell lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I. N. M., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Sep 1 2011, In : Leukemia. 25, 9, p. 1502-1509 8 p.

Research output: Contribution to journalArticle

116 Scopus citations
2012
41 Scopus citations
17 Scopus citations

Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Nowakowski, G. S., Nikcevich, D. A., Nelson, G. D., Yang, Z., Grote, D. M., Ziesmer, S. C., Silberstein, P. T., Erlichman, C. & Witzig, T. E., May 2012, In : Leukemia. 26, 5, p. 1046-1052 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia

Vitale, L. A., He, L. Z., Thomas, L. J., Widger, J., Weidlick, J., Crocker, A., O'Neill, T., Storey, J., Glennie, M. J., Grote, D. M., Ansell, S. M., Marsh, H. & Keler, T., Jul 15 2012, In : Clinical Cancer Research. 18, 14, p. 3812-3821 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Lohr, J. G., Stojanov, P., Lawrence, M. S., Auclair, D., Chapuy, B., Sougnez, C., Cruz-Gordillo, P., Knoechel, B., Asmann, Y. W., Slager, S. L., Novak, A. J., Dogan, A., Ansell, S. M., Link, B. K., Zou, L., Gould, J., Saksena, G., Stransky, N., Rangel-Escareño, C., Fernandez-Lopez, J. C. & 14 others, Hidalgo-Miranda, A., Melendez-Zajgla, J., Hernández-Lemus, E., Schwarz-Cruz y Celis, A., Imaz-Rosshandler, I., Ojesina, A. I., Jung, J., Pedamallu, C. S., Lander, E. S., Habermann, T. M., Cerhan, J. R., Shipp, M. A., Getz, G. & Golub, T. R., Mar 6 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3879-3884 6 p.

Research output: Contribution to journalArticle

590 Scopus citations

Early life sun exposure, vitamin D-related gene variants, and risk of non-Hodgkin lymphoma

Kelly, J. L., Drake, M. T., Fredericksen, Z. S., Asmann, Y. W., Liebow, M., Shanafelt, T. D., Feldman, A. L., Ansell, S. M., Macon, W. R., Herr, M. M., Wang, A. H., Nowakowski, G. S., Call, T. G., Habermann, T. M., Slager, S. L., Witzig, T. E. & Cerhan, J. R., Jul 1 2012, In : Cancer Causes and Control. 23, 7, p. 1017-1029 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
28 Scopus citations

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

Vasmatzis, G., Johnson, S. H., Knudson, R. A., Ketterling, R. P., Braggio, E., Fonseca, R., Viswanatha, D. S., Law, M. E., Kip, N. S., Özsan, N., Grebe, S. K., Frederick, L. A., Eckloff, B. W., Thompson, E. A., Kadin, M. E., Milosevic, D., Porcher, J. C., Asmann, Y. W., Smith, D. I., Kovtun, I. V. & 3 others, Ansell, S. M., Dogan, A. & Feldman, A. L., Sep 13 2012, In : Blood. 120, 11, p. 2280-2289 10 p.

Research output: Contribution to journalArticle

124 Scopus citations

Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma

Charbonneau, B., Maurer, M. J., Fredericksen, Z. S., Zent, C. S., Link, B. K., Novak, A. J., Ansell, S. M., Weiner, G. J., Wang, A. H., Witzig, T. E., Dogan, A., Slager, S. L., Habermann, T. M. & Cerhan, J. R., Sep 1 2012, In : American journal of hematology. 87, 9, p. 880-885 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hodgkin lymphoma: 2012 update on diagnosis, risk-stratification, and management

Ansell, S. M., Dec 1 2012, In : American journal of hematology. 87, 12, p. 1096-1103 8 p.

Research output: Contribution to journalArticle

29 Scopus citations