Stephen Maxted Ansell, MD, PhD

  • 22799 Citations
  • 81 Scopus h-Index
1976 …2020

Research output per year

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Research Output

2011

GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment

Elsawa, S. F., Almada, L. L., Ziesmer, S. C., Novak, A. J., Witzig, T. E., Ansell, S. M. & Fernandez-Zapico, M. E., Jun 17 2011, In : Journal of Biological Chemistry. 286, 24, p. 21524-21534 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Identifying patients with follicular lymphoma who are likely to benefit from an idiotype vaccine

Ansell, S. M. & Suman, V. J., Jul 10 2011, In : Journal of Clinical Oncology. 29, 20, p. 2748-2749 2 p.

Research output: Contribution to journalEditorial

4 Scopus citations

Innate immune B cells gone bad

Ansell, S. M., Nov 7 2011, In : Oncology. 25, 12

Research output: Contribution to journalReview article

Jak/stat pathway in Waldenström's macroglobulinemia

Hodge, L. S. & Ansell, S. M., Feb 1 2011, In : Clinical Lymphoma, Myeloma and Leukemia. 11, 1, p. 112-114 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Lenalidomide can be safely combined with R-CHOP (R2CHOP) in the initial chemotherapy for aggressive B-cell lymphomas: Phase i study

Nowakowski, G. S., Laplant, B., Habermann, T. M., Rivera, C. E., MacOn, W. R., Inwards, D. J., Micallef, I. N., Johnston, P. B., Porrata, L. F., Ansell, S. M., Klebig, R. R., Reeder, C. B. & Witzig, T. E., Dec 1 2011, In : Leukemia. 25, 12, p. 1877-1881 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Low risk of symptomatic venous thromboembolic events during growth factor administration for PBSC mobilization

Naina, H. V., Pruthi, R. K., Inwards, D. J., Dingli, D., Litzow, M. R., Ansell, S. M., William, H. J., Dispenzieri, A., Buadi, F. K., Elliott, M. A., Gastineau, D. A., Gertz, M. A., Hayman, S. R., Johnston, P. B., Lacy, M. Q., Micallef, I. N., Porrata, L. F. & Kumar, S., Feb 1 2011, In : Bone Marrow Transplantation. 46, 2, p. 291-293 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

MicroRNA expression in tumor cells from Waldenstrom's macroglobulinemia reflects both their normal and malignant cell counterparts

Hodge, L. S., Elsawa, S. F., Grote, D. M., Price-Troska, T. L., Asmann, Y. W., Fonseca, R., Gertz, M. A., Witzig, T. E., Novak, A. J. & Ansell, S. M., Jun 1 2011, In : Blood cancer journal. 1, 6, e24.

Research output: Contribution to journalArticle

13 Scopus citations

Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas

Witzig, T. E., Tang, H., Micallef, I. N. M., Ansell, S. M., Link, B. K., Inwards, D. J., Porrata, L. F., Johnston, P. B., Colgan, J. P., Markovic, S. N., Nowakowski, G. S., Thompson, C. A., Allmer, C., Maurer, M. J., Gupta, M., Weiner, G., Hohl, R., Kurtin, P. J., Ding, H., Loegering, D. & 4 others, Schneider, P., Peterson, K., Habermann, T. M. & Kaufmann, S. H., Nov 3 2011, In : Blood. 118, 18, p. 4882-4889 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Novel therapeutic agents for B-cell lymphoma: Developing rational combinations

Reeder, C. B. & Ansell, S. M., Feb 3 2011, In : Blood. 117, 5, p. 1453-1462 10 p.

Research output: Contribution to journalReview article

38 Scopus citations

Predicting PBSC harvest failure using circulating CD34 levels: Developing target-based cutoff points for early intervention

Sinha, S., Gastineau, D., Micallef, I., Hogan, W., Ansell, S., Buadi, F., Dingli, D., Dispenzieri, A., Gertz, M., Greiner, C., Hayman, S., Inwards, D., Johnston, P., Lacy, M., Litzow, M., Porrata, L., Winters, J. L. & Kumar, S., Jul 1 2011, In : Bone Marrow Transplantation. 46, 7, p. 943-949 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Programmed death 1 is expressed in cutaneous infiltrates of mycosis fungoides and Sézary syndrome

Wada, D. A., Wilcox, R. A., Harrington, S. M., Kwon, E. D., Ansell, S. M. & Comfere, N. I., Mar 1 2011, In : American journal of hematology. 86, 3, p. 325-327 3 p.

Research output: Contribution to journalLetter

36 Scopus citations

Soluble IL-2Rα facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma

Yang, Z. Z., Grote, D. M., Ziesmer, S. C., Manske, M. K., Witzig, T. E., Novak, A. J. & Ansell, S. M., Sep 8 2011, In : Blood. 118, 10, p. 2809-2820 12 p.

Research output: Contribution to journalArticle

75 Scopus citations

Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: A multicenter study of 204 skin biopsies

Wada, D. A., Law, M. E., Hsi, E. D., Dicaudo, D. J., Ma, L., Lim, M. S., De Souza, A., Comfere, N. I., Weenig, R. H., MacOn, W. R., Erickson, L. A., Özsan, N., Ansell, S. M., Dogan, A. & Feldman, A. L., Apr 1 2011, In : Modern Pathology. 24, 4, p. 596-605 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: A phase 2 study

Ansell, S. M., Tang, H., Kurtin, P. J., Koenig, P. A., Inwards, D. J., Shah, K., Ziesmer, S. C., Feldman, A. L., Rao, R., Gupta, M., Erlichman, C. & Witzig, T. E., Apr 1 2011, In : The Lancet Oncology. 12, 4, p. 361-368 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

The absolute monocyte and lymphocyte prognostic score predicts survival and identifies high-risk patients in diffuse large-B-cell lymphoma

Wilcox, R. A., Ristow, K., Habermann, T. M., Inwards, D. J., Micallef, I. N. M., Johnston, P. B., Colgan, J. P., Nowakowski, G. S., Ansell, S. M., Witzig, T. E., Markovic, S. N. & Porrata, L., Sep 1 2011, In : Leukemia. 25, 9, p. 1502-1509 8 p.

Research output: Contribution to journalArticle

118 Scopus citations

The definition of IgM multiple myeloma

Schuster, S. R., Rajkumar, S. V., Dispenzieri, A., Morice, W., Aspitia, A. M., Ansell, S., Kyle, R. & Mikhael, J., Aug 1 2011, In : American journal of hematology. 86, 8, p. 718-719 2 p.

Research output: Contribution to journalLetter

1 Scopus citations
2010

A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling

Hildebrand, J. M., Luo, Z., Manske, M. K., Price-Troska, T., Ziesmer, S. C., Lin, W., Hostager, B. S., Slager, S. L., Witzig, T. E., Ansell, S. M., Cerhan, J. R., Bishop, G. A. & Novak, A. J., Nov 22 2010, In : Journal of Experimental Medicine. 207, 12, p. 2569-2579 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma

Younes, A., Vose, J. M., Zelenetz, A. D., Smith, M. R., Burris, H. A., Ansell, S. M., Klein, J., Halpern, W., Miceli, R., Kumm, E., Fox, N. L. & Czuczman, M. S., Dec 7 2010, In : British journal of cancer. 103, 12, p. 1783-1787 5 p.

Research output: Contribution to journalArticle

101 Scopus citations

A phase II study of 153Sm-EDTMP and high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma

Dispenzieri, A., Wiseman, G. A., Lacy, M. Q., Hayman, S. R., Kumar, S. K., Buadi, F., Dingli, D., Laumann, K. M., Allred, J., Geyer, S. M., Litzow, M. R., Gastineau, D. A., Inwards, D. J., Micallef, I. N., Ansell, S. M., Porrata, L., Elliott, M. A., Johnston, P. B., Hogan, W. J. & Gertz, M. A., Jun 1 2010, In : American journal of hematology. 85, 6, p. 409-413 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma

Johnston, P. B., Inwards, D. J., Colgan, J. P., Laplant, B. R., Kabat, B. F., Habermann, T. M., Micallef, I. N., Porrata, L. F., Ansell, S. M., Reeder, C. B., Roy, V. & Witzig, T. E., May 1 2010, In : American journal of hematology. 85, 5, p. 320-324 5 p.

Research output: Contribution to journalArticle

175 Scopus citations

Author reply: Flows and flaws in primary CNS lymphoma

Ansell, S. M. & Rajkumar, S. V., Aug 1 2010, In : Nature Reviews Clinical Oncology. 7, 8

Research output: Contribution to journalLetter

Autologous stem cell transplant for immunoglobulin light chain amyloidosis: A status report

Gertz, M. A., Lacy, M. Q., Dispenzieri, A., Hayman, S. R., Kumar, S. K., Dingli, D., Ansell, S. M., Gastineau, D. A., Inwards, D. J., Johnston, P. B., Litzow, M. R., Micallef, I. N. M., Porrata, L. F., Leung, N., Hogan, W. J. & Buadi, F. K., Dec 1 2010, In : Leukemia and Lymphoma. 51, 12, p. 2181-2187 7 p.

Research output: Contribution to journalArticle

78 Scopus citations
11 Scopus citations

Comparison of error rates in single-arm versus randomized phase II cancer clinical trials

Tang, H., Foster, N. R., Grothey, A., Ansell, S. M., Goldberg, R. M. & Sargent, D. J., Apr 10 2010, In : Journal of Clinical Oncology. 28, 11, p. 1936-1941 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Diagnosis and management of waldenström macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines

Ansell, S. M., Kyle, R. A., Reeder, C. B., Fonseca, R., Mikhael, J. R., Morice, W. G., Bergsagel, P. L., Buadi, F. K., Colgan, J. P., Dingli, D., Dispenzieri, A., Greipp, P. R., Habermann, T. M., Hayman, S. R., Inwards, D. J., Johnston, P. B., Kumar, S. K., Lacy, M. Q., Lust, J. A., Markovic, S. N. & 13 others, Micallef, I. N. M., Nowakowski, G. S., Porrata, L. F., Roy, V., Russell, S. J., Detweiler Short, K. E., Stewart, A. K., Thompson, C. A., Witzig, T. E., Zeldenrust, S. R., Dalton, R. J., Rajkumar, S. V. & Gertz, M. A., Sep 2010, In : Mayo Clinic proceedings. 85, 9, p. 824-833 10 p.

Research output: Contribution to journalReview article

104 Scopus citations

Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma

Kelly, J. L., Novak, A. J., Fredericksen, Z. S., Liebow, M., Ansell, S. M., Dogan, A., Wang, A. H., Witzig, T. E., Call, T. G., Kay, N. E., Habermann, T. M., Slager, S. L. & Cerhan, J. R., Nov 1 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 11, p. 2847-2858 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Hematology: Trials and tribulations in primary CNS lymphoma

Ansell, S. M. & Rajkumar, S. V., Mar 1 2010, In : Nature Reviews Clinical Oncology. 7, 3, p. 125-126 2 p.

Research output: Contribution to journalShort survey

6 Scopus citations

IgM multiple myeloma: Disease definition, prognosis, and differentiation from Waldenstrom's macroglobulinemia

Schuster, S. R., Rajkumar, S. V., Dispenzieri, A., Morice, W., Aspitia, A. M., Ansell, S., Kyle, R. & Mikhael, J., Nov 1 2010, In : American journal of hematology. 85, 11, p. 853-855 3 p.

Research output: Contribution to journalArticle

52 Scopus citations

Inhibition of Syk protein tyrosine kinase induces apoptosis and blocks proliferation in T-cell non-Hodgkin's lymphoma cell lines

Wilcox, R. A., Sun, D. X., Novak, A., Dogan, A., Ansell, S. M. & Feldman, A. L., Jan 2010, In : Leukemia. 24, 1, p. 229-232 4 p.

Research output: Contribution to journalLetter

39 Scopus citations
15 Scopus citations
42 Scopus citations
24 Scopus citations

Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory waldenström macroglobulinemia

Ghobrial, I. M., Gertz, M., LaPlant, B., Camoriano, J., Hayman, S., Lacy, M., Chuma, S., Harris, B., Leduc, R., Rourke, M., Ansell, S. M., DeAngelo, D., Dispenzieri, A., Bergsagel, L., Reeder, C., Anderson, K. C., Richardson, P. G., Treon, S. P. & Witzig, T. E., Mar 10 2010, In : Journal of Clinical Oncology. 28, 8, p. 1408-1414 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Phase i trial of autologous hematopoietic SCT with escalating doses of topotecan combined with CY and carboplatin in patients with relapsed or persistent ovarian or primary peritoneal carcinoma

Litzow, M. R., Peethambaram, P. P., Safgren, S. L., Keeney, G. L., Ansell, S. M., Dispenzieri, A., Elliott, M. A., Gastineau, D. A., Gertz, M. A., Inwards, D. J., Lacy, M. Q., Micallef, I. N. M., Porrata, L. F., Lingle, W. L., Hartmann, L. C., Frost, M. H., Barrette, B. A., Long, H. J., Suman, V. J., Reid, J. M. & 2 others, Ames, M. M. & Kaufmann, S. H., Jan 1 2010, In : Bone Marrow Transplantation. 45, 3, p. 490-497 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Statin use and prognosis in patients with diffuse large B-cell lymphoma and follicular lymphoma in the rituximab era

Nowakowski, G. S., Maurer, M. J., Habermann, T. M., Ansell, S. M., Macon, W. R., Ristow, K. M., Allmer, C., Slager, S. L., Witzig, T. E. & Cerhan, J. R., Jan 20 2010, In : Journal of Clinical Oncology. 28, 3, p. 412-417 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Vitamin D insufficiency and prognosis in non-Hodgkin's lymphoma

Drake, M. T., Maurer, M. J., Link, B. K., Habermann, T. M., Ansell, S. M., Micallef, I. N., Kelly, J. L., Macon, W. R., Nowakowski, G. S., Inwards, D. J., Johnston, P. B., Singh, R. J., Allmer, C., Slager, S. L., Weiner, G. J., Witzig, T. E. & Cerhan, J. R., Sep 20 2010, In : Journal of Clinical Oncology. 28, 27, p. 4191-4198 8 p.

Research output: Contribution to journalArticle

163 Scopus citations
2009
41 Scopus citations

B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders

Wilcox, R. A., Feldman, A. L., Wada, D. A., Yang, Z. Z., Comfere, N. I., Dong, H., Kwon, E. D., Novak, A. J., Markovic, S. N., Pittelkow, M. R., Witzig, T. E. & Ansell, S. M., Nov 20 2009, In : Blood. 114, 10, p. 2149-2158 10 p.

Research output: Contribution to journalArticle

139 Scopus citations

Biologic therapies for non-hodgkin lymphoma and hodgkin disease

Ansell, S. M., Jan 1 2009, Emerging Protein Biotherapeutics. CRC Press, p. 223-245 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cytokines in the microenvironment of Waldenström's macroglobulinemia

Elsawa, S. & Ansell, S., Jan 1 2009, In : Clinical Lymphoma and Myeloma. 9, 1, p. 43-45 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic variation in B-cell-activating factor is associated with an increased risk of developing B-cell non-Hodgkin lymphoma

Novak, A. J., Slager, S. L., Fredericksen, Z. S., Wang, A. H., Manske, M. M., Ziesmer, S., Liebow, M., Macon, W. R., Dillon, S. R., Witzig, T. E., Cerhan, J. R. & Ansell, S. M., May 15 2009, In : Cancer research. 69, 10, p. 4217-4224 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
126 Scopus citations

Intraepithelial Effector (CD3+)/Regulatory (FoxP3+) T-Cell Ratio Predicts a Clinical Outcome of Human Colon Carcinoma

Sinicrope, F. A., Rego, R. L., Ansell, S. M., Knutson, K. L., Foster, N. R. & Sargent, D. J., Oct 2009, In : Gastroenterology. 137, 4, p. 1270-1279 10 p.

Research output: Contribution to journalArticle

187 Scopus citations

Malignant B cells skew the balance of regulatory T cells and T H17 cells in B-cell non-Hodgkin's lymphoma

Yang, Z. Z., Novak, A. J., Ziesmer, S. C., Witzig, T. E. & Ansell, S. M., Jul 1 2009, In : Cancer research. 69, 13, p. 5522-5530 9 p.

Research output: Contribution to journalArticle

113 Scopus citations

Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells

Wilcox, R. A., Wada, D. A., Ziesmer, S. C., Elsawa, S. F., Comfere, N. I., Dietz, A. B., Novak, A. J., Witzig, T. E., Feldman, A. L., Pittelkow, M. R. & Ansell, S. M., Nov 19 2009, In : Blood. 114, 14, p. 2936-2944 9 p.

Research output: Contribution to journalArticle

106 Scopus citations

Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma

Ansell, S. M., Hurvitz, S. A., Koenig, P. A., LaPlant, B. R., Kabat, B. F., Fernando, D., Habermann, T. M., Inwards, D. J., Verma, M., Yamada, R., Erlichman, C., Lowy, I. & Timmerman, J. M., Oct 15 2009, In : Clinical Cancer Research. 15, 20, p. 6446-6453 8 p.

Research output: Contribution to journalArticle

202 Scopus citations

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes

Cerhan, J. R., Novak, A. J., Fredericksen, Z. S., Wang, A. H., Liebow, M., Call, T. G., Dogan, A., Witzig, T. E., Ansell, S. M., Habermann, T. M., Kay, N. E. & Slager, S. L., Jun 1 2009, In : British journal of haematology. 145, 5, p. 614-623 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Serum BLyS levels increase after rituximab as initial therapy in patients with follicular grade 1 non-Hodgkin lymphoma

Ansell, S. M., Novak, A. J., Ziesmer, S., Price-Troska, T., Laplant, B., Dillon, S. R. & Witzig, T. E., Feb 1 2009, In : American journal of hematology. 84, 2, p. 71-73 3 p.

Research output: Contribution to journalArticle

15 Scopus citations

The role of Treg cells in the cancer immunological response

Yang, Z. Z. & Ansell, S. M., Sep 18 2009, In : American Journal of Immunology. 5, 1, p. 17-28 12 p.

Research output: Contribution to journalReview article

15 Scopus citations
2008

A polymorphism in the complement component C1qA correlates with prolonged response following rituximab therapy of follicular lymphoma

Racila, E., Link, B. K., Weng, W. K., Witzig, T. E., Ansell, S., Maurer, M. J., Huang, J., Dahle, C., Halwani, A., Levy, R. & Werner, G. J., Oct 15 2008, In : Clinical Cancer Research. 14, 20, p. 6697-6703 7 p.

Research output: Contribution to journalArticle

113 Scopus citations