Stephen Maxted Ansell, MD, PhD

  • 23318 Citations
  • 81 Scopus h-Index
1989 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Activation-induced T-cell exhaustion: too much of a good thing?

Ansell, S. M., Jan 28 2020, In : Leukemia and Lymphoma. 61, 2, p. 255-256 2 p.

Research output: Contribution to journalComment/debate

A phase 1b study of dual PD-1 and CTLA-4 or KIR blockade in patients with relapsed/refractory lymphoid malignancies

Armand, P., Lesokhin, A., Borrello, I., Timmerman, J., Gutierrez, M., Zhu, L., Popa McKiver, M. & Ansell, S. M., 2020, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Open Access

Brentuximab vedotin with chemotherapy for stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study

Straus, D. J., Długosz-Danecka, M., Alekseev, S., Illés, Á., Picardi, M., Lech-Maranda, E., Feldman, T., Smolewski, P., Savage, K. J., Bartlett, N. L., Walewski, J., Ramchandren, R., Zinzani, P. L., Hutchings, M., Connors, J. M., Radford, J., Munoz, J., Kim, W. S., Advani, R., Ansell, S. M. & 6 others, Younes, A., Miao, H., Liu, R., Fenton, K., Forero-Torres, A. & Gallamini, A., Mar 5 2020, In : Blood. 135, 10, p. 735-742 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Checkpoint inhibition therapy as possible frontline therapy for Hodgkin lymphoma

Khurana, A., Armand, P. & Ansell, S. M., Apr 15 2020, In : Leukemia and Lymphoma. 61, 5, p. 1063-1074 12 p.

Research output: Contribution to journalReview article

1 Scopus citations

Hodgkin lymphoma: A 2020 update on diagnosis, risk-stratification, and management

Ansell, S. M., Aug 1 2020, In : American journal of hematology. 95, 8, p. 978-989 12 p.

Research output: Contribution to journalArticle

Hodgkin lymphoma and PD-1 blockade

Merryman, R., Armand, P. & Ansell, S., 2020, Hematologic Malignancies. Springer, p. 395-409 15 p. (Hematologic Malignancies).

Research output: Chapter in Book/Report/Conference proceedingChapter

IgM AL amyloidosis: delineating disease biology and outcomes with clinical, genomic and bone marrow morphological features

Sidana, S., Larson, D. P., Greipp, P. T., He, R., McPhail, E. D., Dispenzieri, A., Murray, D. L., Dasari, S., Ansell, S. M., Muchtar, E., Gonsalves, W. I., Kourelis, T. V., Ramirez-Alvarado, M., Kapoor, P., Rajkumar, S. V., Lacy, M. Q., Buadi, F. K., Leung, N., Kyle, R. A., Kumar, S. K. & 2 others, King, R. L. & Gertz, M. A., May 1 2020, In : Leukemia. 34, 5, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Immunomodulators in Lymphoma

Anagnostou, T. & Ansell, S. M., Apr 1 2020, In : Current treatment options in oncology. 21, 4, 28.

Research output: Contribution to journalArticle

Immunotherapy in Hodgkin and non-Hodgkin lymphoma: Innate, adaptive and targeted immunological strategies

Tun, A. M. & Ansell, S. M., Aug 2020, In : Cancer Treatment Reviews. 88, 102042.

Research output: Contribution to journalReview article

Immunotherapy of lymphomas

Ansell, S. M. & Lin, Y., Apr 1 2020, In : Journal of Clinical Investigation. 130, 4, p. 1576-1585 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Impact of MYD88L265P mutation status on histological transformation of Waldenström Macroglobulinemia

Zanwar, S., Abeykoon, J. P., Durot, E., King, R., Perez Burbano, G. E., Kumar, S., Gertz, M. A., Quinquenel, A., Delmer, A., Gonsalves, W., Cornillet-Lefebvre, P., He, R., Warsame, R., Buadi, F. K., Novak, A. J., Greipp, P. T., Inwards, D., Habermann, T. M., Micallef, I., Go, R. & 19 others, Muchtar, E., Kourelis, T., Dispenzieri, A., Lacy, M. Q., Dingli, D., Nowakowski, G., Thompson, C. A., Johnston, P., Thanarajasingam, G., Bennani, N. N., Witzig, T. E., Villasboas, J., Leung, N., Lin, Y., Kyle, R. A., Rajkumar, S. V., Ansell, S. M., Le-Rademacher, J. G. & Kapoor, P., Mar 1 2020, In : American journal of hematology. 95, 3, p. 274-281 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

NCCN Guidelines Insights: Primary Cutaneous Lymphomas, Version 2.2020

Mehta-Shah, N., Horwitz, S. M., Ansell, S., Ai, W. Z., Barnes, J., Barta, S. K., Clemens, M. W., Dogan, A., Fisher, K., Goodman, A. M., Goyal, G., Guitart, J., Halwani, A., Haverkos, B. M., Hoppe, R. T., Jacobsen, E., Jagadeesh, D., Lunning, M. A., Mehta, A., Olsen, E. A. & 14 others, Pro, B., Rajguru, S. A., Shanbhag, S., Shaver, A., Shustov, A., Sokol, L., Torka, P., Torres-Cabala, C., Wilcox, R., William, B. M., Zain, J., Dwyer, M. A., Sundar, H. & Kim, Y. H., May 1 2020, In : Journal of the National Comprehensive Cancer Network : JNCCN. 18, 5, p. 522-536 15 p.

Research output: Contribution to journalArticle

Open Access

Persistent mediastinal FDG uptake on PET-CT after frontline therapy for Hodgkin lymphoma: biopsy, treat or observe?

Novo, M., Nowakowski, G. S., Habermann, T. M., Witzig, T. E., Micallef, I. N., Johnston, P. B., Inwards, D. J., Botto, B., Ristow, K. M., Young, J. R., Vitolo, U. & Ansell, S. M., Jan 28 2020, In : Leukemia and Lymphoma. 61, 2, p. 318-327 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Role of Microenvironment in Non-Hodgkin Lymphoma: Understanding the Composition and Biology

Khurana, A. & Ansell, S. M., May 1 2020, In : Cancer journal (Sudbury, Mass.). 26, 3, p. 206-216 11 p.

Research output: Contribution to journalArticle

Safety and activity of varlilumab, a novel and first-in-class agonist anti-CD27 antibody, for hematologic malignancies

Ansell, S. M., Flinn, I., Taylor, M. H., Sikic, B. I., Brody, J., Nemunaitis, J., Feldman, A., Hawthorne, T. R., Rawls, T., Keler, T. & Yellin, M. J., May 12 2020, In : Blood Advances. 4, 9, p. 1917-1926 10 p.

Research output: Contribution to journalArticle

Open Access

Targeting of inflammatory pathways with R2CHOP in high-risk DLBCL

Hartert, K. T., Wenzl, K., Krull, J. E., Manske, M., Sarangi, V., Asmann, Y., Larson, M. C., Maurer, M. J., Slager, S., Macon, W. R., King, R. L., Feldman, A. L., Gandhi, A. K., Link, B. K., Habermann, T. M., Yang, Z. Z., Ansell, S. M., Cerhan, J. R., Witzig, T. E., Nowakowski, G. S. & 1 others, Novak, A. J., 2020, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

The immune landscape and response to immune checkpoint blockade therapy in lymphoma

Kline, J., Godfrey, J. & Ansell, S. M., Feb 20 2020, In : Blood. 135, 8, p. 523-533 11 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Three-year outcomes with brentuximab vedotin plus bendamustine as first salvage therapy in relapsed or refractory Hodgkin lymphoma

LaCasce, A. S., Bociek, R. G., Sawas, A., Caimi, P., Agura, E., Matous, J., Ansell, S. M., Crosswell, H. E., Islas-Ohlmayer, M., Behler, C., Cheung, E., Forero-Torres, A., Vose, J., O’Connor, O. A., Josephson, N., Wang, Y. & Advani, R., Jan 1 2020, (Accepted/In press) In : British journal of haematology.

Research output: Contribution to journalLetter

Open Access
1 Scopus citations
2019

Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma

Wang, Y., Wenzl, K., Manske, M. K., Asmann, Y., Sarangi, V., Greipp, P. T., Krull, J. E., Hartert, K., He, R., Feldman, A. L., Maurer, M. J., Slager, S. L., Nowakowski, G. S., Habermann, T. M., Witzig, T. E., Link, B. K., Ansell, S. M., Cerhan, J. R. & Novak, A. J., Sep 1 2019, In : Blood cancer journal. 9, 9, 73.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

An RNA aptamer-based biomarker platform demonstrates high soluble cd25 occupancy by il2 in the serum of follicular lymphoma patients

Veeramani, S., Blackwell, S. E., Thiel, W. H., Yang, Z. Z., Ansell, S. M., Giangrande, P. H. & Weiner, G. J., Jan 1 2019, In : Cancer Immunology Research. 7, 9, p. 1511-1522 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Association between facility volume and mortality of patients with classic Hodgkin lymphoma

Goyal, G., Tella, S. H., Funni, S., Kommalapati, A., Inselman, J. W., Shah, N. D., Go, R. S. & Ansell, S. M., Jan 1 2019, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

1 Scopus citations

Autograft immune content and survival in non-Hodgkin's lymphoma: A post hoc analysis

Porrata, L. F., Inwards, D. J., Ansell, S. M., Micallef, I. N., Johnston, P. B., Villasboas, J. C. & Markovic, S. N., Jun 2019, In : Leukemia Research. 81, p. 1-9 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Bleomycin use in the treatment of Hodgkin lymphoma (HL): toxicity and outcomes in the modern era

Taparra, K., Liu, H., Polley, M. Y., Ristow, K., Habermann, T. M. & Ansell, S. M., Jan 1 2019, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

Brentuximab Vedotin plus Chemotherapy in North American Subjects with Newly Diagnosed Stage III or IV Hodgkin Lymphoma

Ramchandren, R., Advani, R. H., Ansell, S. M., Bartlett, N. L., Chen, R., Connors, J. M., Feldman, T., Forero-Torres, A., Friedberg, J. W., Gopal, A. K., Gordon, L. I., Kuruvilla, J., Savage, K. J., Younes, A., Engley, G., Manley, T. J., Fenton, K. & Straus, D. J., 2019, In : Clinical Cancer Research. 25, 6, p. 1718-1726 9 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Cause of death in follicular lymphoma in the first decade of the rituximab era: A pooled analysis of French and US cohorts

Sarkozy, C., Maurer, M. J., Link, B. K., Ghesquieres, H., Nicolas, E., Thompson, C. A., Traverse-Glehen, A., Feldman, A. L., Allmer, C., Slager, S. L., Ansell, S. M., Habermann, T. M., Bachy, E., Cerhan, J. R. & Salles, G., Jan 10 2019, In : Journal of Clinical Oncology. 37, 2, p. 144-152 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Comparison of the NCCN-IPI, the IPI and PIT scores as prognostic tools in peripheral T-cell lymphomas

Ellin, F., Maurer, M. J., Srour, L., Farooq, U., Jerkeman, M., Connors, J. M., Smedby, K. E., Bennani, N. N., Ansell, S. M., Slack, G. W., Cerhan, J. R., Relander, T., Feldman, A. L. & Savage, K. J., Aug 2019, In : British journal of haematology. 186, 3, p. e24-e27

Research output: Contribution to journalLetter

Open Access

Detection of extranodal and spleen involvement by FDG-PET imaging predicts adverse survival in untreated follicular lymphoma

St-Pierre, F., Broski, S. M., LaPlant, B. R., Ristow, K., Maurer, M. J., Macon, W. R., Habermann, T. M., Ansell, S. M., Thompson, C. A., Micallef, I. N. M., Nowakowski, G. S. & Witzig, T. E., Jul 2019, In : American journal of hematology. 94, 7, p. 786-793 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes

Din, L., Sheikh, M., Kosaraju, N., Smedby, K. E., Bernatsky, S., Berndt, S. I., Skibola, C. F., Nieters, A., Wang, S., McKay, J. D., Cocco, P., Maynadié, M., Foretová, L., Staines, A., Mack, T. M., de Sanjosé, S., Vyse, T. J., Padyukov, L., Monnereau, A., Arslan, A. A. & 72 others, Moore, A., Brooks-Wilson, A. R., Novak, A. J., Glimelius, B., Birmann, B. M., Link, B. K., Stewart, C., Vajdic, C. M., Haioun, C., Magnani, C., Conti, D. V., Cox, D. G., Casabonne, D., Albanes, D., Kane, E., Roman, E., Muzi, G., Salles, G., Giles, G. G., Adami, H. O., Ghesquières, H., De Vivo, I., Clavel, J., Cerhan, J. R., Spinelli, J. J., Hofmann, J., Vijai, J., Curtin, K., Costenbader, K. H., Onel, K., Offit, K., Teras, L. R., Morton, L., Conde, L., Miligi, L., Melbye, M., Ennas, M. G., Liebow, M., Purdue, M. P., Glenn, M., Southey, M. C., Din, M., Rothman, N., Camp, N. J., Wong Doo, N., Becker, N., Pradhan, N., Bracci, P. M., Boffetta, P., Vineis, P., Brennan, P., Kraft, P., Lan, Q., Severson, R. K., Vermeulen, R. C. H., Milne, R. L., Kaaks, R., Travis, R. C., Weinstein, S. J., Chanock, S. J., Ansell, S. M., Slager, S. L., Zheng, T., Zhang, Y., Benavente, Y., Taub, Z., Madireddy, L., Gourraud, P. A., Oksenberg, J. R., Cozen, W., Hjalgrim, H. & Khankhanian, P., Oct 1 2019, In : Genetic epidemiology. 43, 7, p. 844-863 20 p.

Research output: Contribution to journalArticle

8 Scopus citations

Ibrutinib for the treatment of Bing-Neel syndrome: A multicenter study

Castillo, J. J., Itchaki, G., Paludo, J., Varettoni, M., Buske, C., Eyre, T. A., Chavez, J. C., Shain, K. H., Issa, S., Palomba, M. L., Pasvolsky, O., Simpson, D., Talaulikar, D., Tam, C. S., Tedeschi, A., Ansell, S. M., Nayak, L. & Treon, S. P., Jan 24 2019, In : Blood. 133, 4, p. 299-305 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
7 Scopus citations

Immunotherapy in Hodgkin Lymphoma: The Road Ahead

Ansell, S. M., May 2019, In : Trends in Immunology. 40, 5, p. 380-386 7 p.

Research output: Contribution to journalReview article

2 Scopus citations

Immunotransplant: Preventing unintended consequences

Ansell, S. M., Nov 2019, In : Cancer discovery. 9, 11, p. 1487-1489 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Impact of concurrent indolent lymphoma on the clinical outcome of newly diagnosed diffuse large B-cell lymphoma

Wang, Y., Link, B. K., Witzig, T. E., Maurer, M. J., Allmer, C., King, R. L., Feldman, A. L., Habermann, T. M., Ansell, S. M., Slager, S. L., Cerhan, J. R. & Nowakowski, G. S., Oct 17 2019, In : Blood. 134, 16, p. 1289-1297 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2 Scopus citations

Late relapses in patients with diffuse large b-cell lymphoma treated with immunochemotherapy

Wang, Y., Farooq, U., Link, B. K., Larson, M. C., King, R., Maurer, M. J., Allmer, C., Hefazi, M., Thompson, C. A., Micallef, I., Johnston, P. B., Habermann, T. M., Witzig, T. E., Ansell, S. M., Cerhan, J. R. & Nowakowski, G. S., Jul 20 2019, In : Journal of Clinical Oncology. 37, 21, p. 1819-1827 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mass Cytometry Analysis Reveals that Specific Intratumoral CD4 + T Cell Subsets Correlate with Patient Survival in Follicular Lymphoma

Yang, Z. Z., Kim, H. J., Villasboas, J. C., Price-Troska, T., Jalali, S., Wu, H., Luchtel, R. A., Polley, M. Y. C., Novak, A. J. & Ansell, S. M., Feb 19 2019, In : Cell reports. 26, 8, p. 2178-2193.e3

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Nivolumab for newly diagnosed advanced-stage classic Hodgkin lymphoma: Safety and efficacy in the phase II CheckMate 205 study

Ramchandren, R., Domingo-Domènech, E., Rueda, A., Trněný, M., Feldman, T. A., Lee, H. J., Provencio, M., Sillaber, C., Cohen, J. B., Savage, K. J., Willenbacher, W., Ligon, A. H., Ouyang, J., Redd, R., Rodig, S. J., Shipp, M. A., Sacchi, M., Sumbul, A., Armand, P. & Ansell, S. M., Aug 10 2019, In : Journal of Clinical Oncology. 37, 23, p. 1997-2007 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Nivolumab for relapsed/refractory diffuse large B-cell lymphoma in patients ineligible for or having failed autologous transplantation: A single-arm, phase II study

Ansell, S. M., Minnema, M. C., Johnson, P., Timmerman, J. M., Armand, P., Shipp, M. A., Rodig, S. J., Ligon, A. H., Roemer, M. G. M., Reddy, N., Cohen, J. B., Assouline, S., Poon, M., Sharma, M., Kato, K., Samakoglu, S., Sumbul, A. & Grigg, A., 2019, In : Journal of Clinical Oncology. 37, 6, p. 481-489 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Pembrolizumab: Living up to expectations

Ansell, S. M., Oct 3 2019, In : Blood. 134, 14, p. 1114-1115 2 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Prognostic significance of PD-L1 and TLR5 expression in peripheral T-cell lymphomas

Zanwar, S. & Ansell, S. M., Jan 1 2019, In : Leukemia and Lymphoma.

Research output: Contribution to journalComment/debate

Progression risk stratification of asymptomatic Waldenström macroglobulinemia

Bustoros, M., Sklavenitis-Pistofidis, R., Kapoor, P., Liu, C. J., Kastritis, E., Zanwar, S., Fell, G., Abeykoon, J. P., Hornburg, K., Neuse, C. J., Marinac, C. R., Liu, D., Soiffer, J., Gavriatopoulou, M., Boehner, C., Cappuccio, J. M., Dumke, H., Reyes, K., Soiffer, R. J., Kyle, R. A. & 6 others, Treon, S. P., Castillo, J. J., Dimopoulos, M. A., Ansell, S. M., Trippa, L. & Ghobrial, I. M., 2019, In : Journal of Clinical Oncology. 37, 16, p. 1403-1411 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Recurrent MSCE116K mutations in ALK-negative anaplastic large cell lymphoma

Luchtel, R. A., Zimmermann, M. T., Hu, G., Dasari, S., Jiang, M., Oishi, N., Jacobs, H. K., Zeng, Y., Hundal, T., Rech, K. L., Ketterling, R. P., Lee, J. H., Eckloff, B. W., Yan, H., Gaonkar, K. S., Tian, S., Ye, Z., Kadin, M. E., Sidhu, J., Jiang, L. & 11 others, Voss, J., Link, B. K., Syrbu, S. I., Facchetti, F., Bennani, N. N., Slager, S. L., Ordog, T., Kocher, J. P., Cerhan, J. R., Ansell, S. M. & Feldman, A. L., Jun 27 2019, In : Blood. 133, 26, p. 2776-2789 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Reverse signaling via PD-L1 supports malignant cell growth and survival in classical Hodgkin lymphoma

Jalali, S., Price-Troska, T., Bothun, C., Villasboas Bisneto, J. J. C. ., Kim, H. J., Yang, Z. Z., Novak, A. J., Dong, H. M. & Ansell, S. M., Mar 1 2019, In : Blood cancer journal. 9, 3, 22.

Research output: Contribution to journalArticle

7 Scopus citations

Sintilimab: another effective immune checkpoint inhibitor in classical Hodgkin lymphoma

Ansell, S. M., Jan 1 2019, In : The Lancet Haematology. 6, 1, p. e2-e3

Research output: Contribution to journalComment/debate

SIRPα expression delineates subsets of intratumoral monocyte/macrophages with different functional and prognostic impact in follicular lymphoma

Chen, Y. P., Kim, H. J., Wu, H., Price-Troska, T., Villasboas, J. C., Jalali, S., Feldman, A. L., Novak, A. J., Yang, Z. Z. & Ansell, S. M., Oct 1 2019, In : Blood cancer journal. 9, 10, 84.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

Wu, X., Stenson, M., Abeykoon, J., Nowakowski, K., Zhang, L., Lawson, J., Wellik, L., Li, Y., Krull, J., Wenzl, K., Novak, A. J., Ansell, S. M., Bishop, G. A., Billadeau, D. D., Peng, K. W., Giles, F., Schmitt, D. M. & Witzig, T. E., Jul 25 2019, In : Blood. 134, 4, p. 363-373 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

The highs and lows of immune-checkpoint blockade in lymphoma

Ansell, S. M., May 1 2019, In : Cancer Immunology Research. 7, 5, p. 696-700 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

The potential role of glycogen metabolism in diffuse large B-cell lymphoma

Jalali, S. & Ansell, S. M., Jan 1 2019, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalReview article

Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis

Wang, Y., Zhou, S., Yang, F., Qi, X., Wang, X., Guan, X., Shen, C., Duma, N., Vera Aguilera, J., Chintakuntlawar, A., Price, K. A., Molina, J. R., Pagliaro, L., Halfdanarson, T. R., Grothey, A., Markovic, S. N., Nowakowski, G. S., Ansell, S. M. & Wang, M. L., Jul 2019, In : JAMA Oncology. 5, 7, p. 1008-1019 12 p.

Research output: Contribution to journalReview article

78 Scopus citations

Tumor microenvironment in T-Cell lymphomas

Bennani, N. & Ansell, S. M., Jan 1 2019, Cancer Treatment and Research. Springer International Publishing, p. 69-82 14 p. (Cancer Treatment and Research; vol. 176).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations