Robert B Diasio, MD

Professor

  • 13369 Citations
  • 65 h-Index
1965 …2019
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Fluorouracil Medicine & Life Sciences
Dihydrouracil Dehydrogenase (NADP) Medicine & Life Sciences
Dihydropyrimidine Dehydrogenase Deficiency Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Pharmacogenetics Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences
Antineoplastic Antimetabolites Medicine & Life Sciences
Thymidine Phosphorylase Medicine & Life Sciences

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Projects 1978 2019

Fluorouracil
Uracil
Oxidoreductases
Breath Tests
dihydropyrimidinase
Dihydrouracil Dehydrogenase (NADP)
Thymidylate Synthase
Fluorouracil
Colorectal Neoplasms
Human Genome Project
Dihydrouracil Dehydrogenase (NADP)
Genetic Polymorphisms
Fluorouracil
Dihydropyrimidine Dehydrogenase Deficiency
Gene Expression
Fluorouracil
beta-Alanine
Liver
Bile Acids and Salts
Bile

CANCER CENTER SUPPORT REVIEW COMMITTEE

Diasio, R. B., Eckhart, W., Mittman, C., O'Brien, R., Rifkind, R., Simone, J. V., Simone, J., Kovach, J. S., Blum, R., Wicha, M. S., Gallo, M. A., Doroshow, J., Moses, H., Willson, J. K., Eckhart, W., Mittman, C., Rifkind, R., Simone, J. V., Wicha, M. S., Gallo, M. A., Doroshow, J., Willson, J. K., O'Brien, R., Kovach, J. S., Blum, R., Moses, H. & Simone, J.

National Institutes of Health

9/30/849/30/05

Project: Research project

Research Output 1965 2018

  • 13369 Citations
  • 65 h-Index
  • 243 Article
  • 15 Chapter
  • 1 Comment/debate
  • 1 Review article
4 Citations (Scopus)

Gene-Specific Variant Classifier (DPYD-Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase

Shrestha, S., Zhang, C., Jerde, C. R., Nie, Q., Li, H., Offer, S. M. & Diasio, R. B., Jan 1 2018, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Fluorouracil
Alleles
Precision Medicine
Computer Simulation

Pharmacogenomics and the role of genomics in cancer therapeutics

Offer, S. M. & Diasio, R. B., Jan 1 2018, Cancer Chemotherapy, Immunotherapy and Biotherapy: Principles and Practice, Sixth Edition. Wolters Kluwer Health, p. 49-68 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmacogenetics
Genomics
Neoplasms
Therapeutics
3 Citations (Scopus)

Therapeutic Drug Monitoring in Oncology: International Association of Therapeutic Drug Monitoring and Clinical Toxicology Recommendations for 5-Fluorouracil Therapy

Beumer, J. H., Chu, E., Allegra, C., Tanigawara, Y., Milano, G., Diasio, R. B., Kim, T. W., Mathijssen, R. H., Zhang, L., Arnold, D., Muneoka, K., Boku, N. & Joerger, M., Jan 1 2018, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Drug Monitoring
Fluorouracil
Toxicology
Body Surface Area
Head and Neck Neoplasms
32 Citations (Scopus)

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

Amstutz, U., Henricks, L. M., Offer, S. M., Barbarino, J., Schellens, J. H. M., Swen, J. J., Klein, T. E., Mcleod, H. L., Caudle, K. E., Diasio, R. B. & Schwab, M., Jan 1 2017, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Pharmacogenetics
Genotype
Guidelines
Clinical Pharmacology
2 Citations (Scopus)

Drug metabolism and pancreatic cancer

Flores, J. P. E., Diasio, R. B. & Saif, M. W., 2017, In : Annals of Gastroenterology. 30, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Precision Medicine
Pharmaceutical Preparations
Costs and Cost Analysis
Therapeutics