• 14006 Citations
  • 66 Scopus h-Index
1965 …2020

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Article
2020

Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Trial of the ECOG-ACRIN Research Group (E5204)

Chakravarthy, A. B., Zhao, F., Meropol, N. J., Flynn, P. J., Wagner, L. I., Sloan, J., Diasio, R. B., Mitchell, E. P., Catalano, P., Giantonio, B. J., Catalano, R. B., Haller, D. G., Awan, R. A., Mulcahy, M. F., O'Brien, T. E., Santala, R., Cripps, C., Weis, J. R., Atkins, J. N., Leichman, C. G. & 9 others, Petrelli, N. J., Sinicrope, F. A., Brierley, J. D., Tepper, J. E., O'Dwyer, P. J., Sigurdson, E. R., Hamilton, S. R., Cella, D. & Benson, A. B., May 1 2020, In : Oncologist. 25, 5, p. e798-e807

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Optimal Lymph Node Examination and Adjuvant Chemotherapy for Stage I Lung Cancer

Dai, J., Liu, M., Yang, Y., Li, Q., Song, N., Rocco, G., Sihoe, A. D. L., Gonzalez-Rivas, D., Suen, H. C., He, W., Duan, L., Fan, J., Zhao, D., Wang, H., Zhu, Y., Chen, C., Diasio, R. B., Jiang, G., Yang, P. & Zhang, P., Jul 2019, In : Journal of Thoracic Oncology. 14, 7, p. 1277-1285 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

T4 extension alone is more predictive of better survival than a tumour size >7 cm for resected T4N0-1M0 non-small-cell lung cancer

Li, Q., Zhang, P., Wang, Y., Liu, D., Luo, L., Diasio, R. B., Yang, P. & Jiang, G., Apr 1 2019, In : European Journal of Cardio-Thoracic Surgery. 55, 4, p. 682-690 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

Amstutz, U., Henricks, L. M., Offer, S. M., Barbarino, J., Schellens, J. H. M., Swen, J. J., Klein, T. E., McLeod, H. L., Caudle, K. E., Diasio, R. B. & Schwab, M., Feb 2018, In : Clinical pharmacology and therapeutics. 103, 2, p. 210-216 7 p.

Research output: Contribution to journalArticle

88 Scopus citations

Dose modification for safe treatment of a compound complex heterozygous DPYD variant carrier with fluorouracil

Shrestha, S., Tapper, E. E., Trogstad-Isaacson, C., Hobday, T. J., Offer, S. M. & Diasio, R. B., Jan 1 2018, In : JCO Precision Oncology. 2

Research output: Contribution to journalArticle

Gene-Specific Variant Classifier (DPYD-Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase

Shrestha, S., Zhang, C., Jerde, C. R., Nie, Q., Li, H., Offer, S. M. & Diasio, R. B., Jan 1 2018, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Drug metabolism and pancreatic cancer

Flores, J. P. E., Diasio, R. B. & Saif, M. W., 2017, In : Annals of Gastroenterology. 30, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Quantitative Contribution of rs75017182 to Dihydropyrimidine Dehydrogenase mRNA Splicing and Enzyme Activity

Nie, Q., Shrestha, S., Tapper, E., Trogstad-Isaacson, C., Bouchonville, K., Lee, A., Wu, R., Jerde, C., Wang, Z., Kubica, P., Offer, S. & Diasio, R. B., 2017, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

13 Scopus citations
2016

Acquired factor VII deficiency following FOLFOX in a patient with colorectal cancer who was also DPD deficient

Saif, M. W., Wasif, K., Butler-Bowen, H., Miller, K. & Diasio, R. B., Jan 1 2016, In : Therapeutic Advances in Gastroenterology. 9, 1, p. 121-127 7 p.

Research output: Contribution to journalArticle

A phosphotyrosine switch regulates organic cation transporters

Sprowl, J. A., Ong, S. S., Gibson, A. A., Hu, S., Du, G., Lin, W., Li, L., Bharill, S., Ness, R. A., Stecula, A., Offer, S. M., Diasio, R. B., Nies, A. T., Schwab, M., Cavaletti, G., Schlatter, E., Ciarimboli, G., Schellens, J. H. M., Isacoff, E. Y., Sali, A. & 4 others, Chen, T., Baker, S. D., Sparreboom, A. & Pabla, N., Mar 16 2016, In : Nature Communications. 7, 10880.

Research output: Contribution to journalArticle

41 Scopus citations

Association between DPYD c.1129-5923 C>G/hapB3 and severe toxicity to 5-fluorouracil-based chemotherapy in stage III colon cancer patients: NCCTG N0147 (Alliance)

Lee, A. M., Shi, Q., Alberts, S. R., Sargent, D. J., Sinicrope, F. A., Berenberg, E. L., Grothey, A., Polite, B., Chan, E., Gill, S., Kahlenberg, M. S., Nair, S. G., Shields, A. F., Goldberg, R. M. & Diasio, R. B., Jan 1 2016, In : Pharmacogenetics and genomics. 26, 3, p. 133-137 5 p.

Research output: Contribution to journalArticle

19 Scopus citations
12 Scopus citations

Histone H3K27 trimethylation modulates 5-fluorouracil resistance by inhibiting PU.1 binding to the DPYD promoter

Wu, R., Nie, Q., Tapper, E. E., Jerde, C. R., Dunlap, G. S., Shrestha, S., Elraiyah, T. A., Offer, S. M. & Diasio, R. B., Nov 1 2016, In : Cancer Research. 76, 21, p. 6362-6373 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Imatinib-induced hyperbilirubinemia with UGT1A1 (*28) promoter polymorphism: First case series in patients with gastrointestinal stromal tumor

Saif, M. W., Smith, M. H., Maloney, A. & Diasio, R. B., 2016, In : Annals of Gastroenterology. 29, 4, p. 551-556 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Is it finally time for a personalized medicine approach for fluorouracil-based therapies?

Offer, S. M. & Diasio, R. B., Jan 20 2016, In : Journal of Clinical Oncology. 34, 3, p. 205-207 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Novel Deleterious Dihydropyrimidine Dehydrogenase Variants May Contribute to 5-Fluorouracil Sensitivity in an East African Population

Elraiyah, T., Jerde, C. R., Shrestha, S., Wu, R., Nie, Q., Giama, N. H., Sarangi, V., Roberts, L. R., Offer, S. M. & Diasio, R. B., 2016, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

11 Scopus citations

Value, access, and cost of cancer care delivery at academic cancer centers

Nardi, E. A., Wolfson, J. A., Rosen, S. T., Diasio, R. B., Gerson, S. L., Parker, B. A., Alvarnas, J. C., Levine, H. A., Fong, Y., Weisenburger, D. D., Fitzgerald, C. L., Egan, M., Stranford, S., Carlson, R. W. & Benz, E. J., Jul 1 2016, In : JNCCN Journal of the National Comprehensive Cancer Network. 14, 7, p. 837-847 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Common oncogene mutations and novel SND1-BRAF transcript fusion in lung adenocarcinoma from never smokers

Jang, J. S., Lee, A., Li, J., Liyanage, H., Yang, Y. D., Guo, L., Asmann, Y., Li, P. W., Erickson-Johnson, M., Sakai, Y., Sun, Z. D., Jeon, H. S., Hwang, H., Bungum, A. O., Edell, E., Simon, V. A., Kopp, K. J., Eckloff, B., Oliveira, A. M., Wieben, E. D. & 6 others, Aubry, M. C., Yi, E., Wigle, D. A., Diasio, R. B., Yang, P. & Jen, J., May 18 2015, In : Scientific Reports. 5, 9755.

Research output: Contribution to journalArticle

28 Scopus citations

Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients

Ziv, E., Dean, E., Hu, D., Martino, A., Serie, D., Curtin, K., Campa, D., Aftab, B., Bracci, P., Buda, G., Zhao, Y., Caswell-Jin, J., Diasio, R. B., Dumontet, C., Dudziński, M., Fejerman, L., Greenberg, A., Huntsman, S., Jamroziak, K., Jurczyszyn, A. & 18 others, Kumar, S. K., Atanackovic, D., Glenn, M., Cannon-Albright, L. A., Jones, B., Lee, A., Marques, H., Martin, T., Martinez-Lopez, J., Rajkumar, S. V., Sainz, J., Vangsted, A. J., Wątek, M., Wolf, J., Slager, S. L., Camp, N. J., Canzian, F. & Vachon, C. M., Jul 22 2015, In : Nature Communications. 6, 7539.

Research output: Contribution to journalArticle

21 Scopus citations

Polymorphisms in MIR27A associated with early-onset toxicity in fluoropyrimidine-based chemotherapy

Amstutz, U., Offer, S. M., Sistonen, J., Joerger, M., Diasio, R. B. & Largiader, C. R., May 1 2015, In : Clinical Cancer Research. 21, 9, p. 2038-2044 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
2014

A DPYD variant (y186c) specific to individuals of african descent in a patient with life-threatening 5-fu toxic effects: Potential for an individualized medicine approach

Saif, M. W., Lee, A. M., Offer, S. M., McConnell, K., Relias, V. & Diasio, R. B., Jan 2014, In : Mayo Clinic proceedings. 89, 1, p. 131-136 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
35 Scopus citations

Comparative functional analysis of dpyd variants of potential clinical relevance to dihydropyrimidine dehydrogenase activity

Offer, S. M., Fossum, C. C., Wegner, N. J., Stuflesser, A. J., Butterfield, G. L. & Diasio, R. B., Jan 5 2014, In : Cancer research. 74, 9, p. 2545-2554 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147)

Lee, A. M., Shi, Q., Pavey, E., Alberts, S. R., Sargent, D. J., Sinicrope, F. A., Berenberg, J. L., Goldberg, R. M. & Diasio, R. B., Dec 1 2014, In : Journal of the National Cancer Institute. 106, 12, dju298.

Research output: Contribution to journalArticle

79 Scopus citations

Epigenetic mechanisms of protein tyrosine phosphatase 6 suppression in diffuse large B-cell lymphoma: Implications for epigenetic therapy

Witzig, T. E., Hu, G., Offer, S. M., Wellik, L. E., Han, J. J., Stenson, M. J., Dogan, A., Diasio, R. B. & Gupta, M., Jan 1 2014, In : Leukemia. 28, 1, p. 147-154 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

HER-2/neu gene amplification in relation to expression of HER2 and HER3 proteins in patients with esophageal adenocarcinoma

Yoon, H. H., Sukov, W. R., Shi, Q., Sattler, C. A., Wiktor, A. E., Diasio, R. B., Wu, T. T., Jenkins, R. B. & Sinicrope, F. A., Feb 1 2014, In : Cancer. 120, 3, p. 415-424 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sites

Offer, S. M., Butterfield, G. L., Jerde, C. R., Fossum, C. C., Wegner, N. J. & Diasio, R. B., Mar 2014, In : Molecular cancer therapeutics. 13, 3, p. 742-751 10 p.

Research output: Contribution to journalArticle

49 Scopus citations
2013

A DPYD variant (Y186C) in individuals of african ancestry is associated with reduced DPD enzyme activity

Offer, S. M., Lee, A. M., Mattison, L. K., Fossum, C., Wegner, N. J. & Diasio, R. B., Jul 1 2013, In : Clinical pharmacology and therapeutics. 94, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

A phase II study of modulated-capecitabine and docetaxel in chemonaive patients with advanced non-small cell lung cancer (NSCLC)

Bertino, E. M., Bekaii-Saab, T., Fernandez, S., Diasio, R. B., Karim, N. A., Otterson, G. A. & Villalona-Calero, M. A., Jan 1 2013, In : Lung Cancer. 79, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Fatty acid binding protein 3 (fabp3) is associated with insulin, lipids and cardiovascular phenotypes of the metabolic syndrome through epigenetic modifications in a northern european family population

Zhang, Y., Kent, J. W., Lee, A., Cerjak, D., Ali, O., Diasio, R., Olivier, M., Blangero, J., Carless, M. A. & Kissebah, A. H., Mar 21 2013, In : BMC medical genomics. 6, 1, 9.

Research output: Contribution to journalArticle

31 Scopus citations

Phenotypic profiling of DPYD variations relevant to 5-fluorouracil sensitivity using real-time cellular analysis and in vitro measurement of enzyme activity

Offer, S. M., Wegner, N. J., Fossum, C., Wang, K. & Diasio, R. B., Mar 15 2013, In : Cancer research. 73, 6, p. 1958-1968 11 p.

Research output: Contribution to journalArticle

61 Scopus citations
2012

Adverse prognostic impact of intratumor heterogeneous HER2 gene amplification in patients with esophageal adenocarcinoma

Yoon, H. H., Shi, Q., Sukov, W. R., Lewis, M. A., Sattler, C. A., Wiktor, A. E., Wu, T. T., Diasio, R. B., Jenkins, R. B. & Sinicrope, F. A., Nov 10 2012, In : Journal of Clinical Oncology. 30, 32, p. 3932-3938 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

Australian Breast Cancer Tissue Bank Investigators, 2012, In : Human molecular genetics. 21, 24, p. 5373-5384 12 p.

Research output: Contribution to journalArticle

131 Scopus citations

Association of HER2/ErbB2 expression and gene amplification with pathologic features and prognosis in esophageal adenocarcinomas

Yoon, H. H., Shi, Q., Sukov, W. R., Wiktor, A. E., Khan, M., Sattler, C. A., Grothey, A., Wu, T. T., Diasio, R. B., Jenkins, R. B. & Sinicrope, F. A., Jan 15 2012, In : Clinical Cancer Research. 18, 2, p. 546-554 9 p.

Research output: Contribution to journalArticle

95 Scopus citations

EGFR somatic mutations in lung tumors: Radon exposure and passive smoking in former- and never-smoking U.S. women

Taga, M., Mechanic, L. E., Hagiwara, N., Vähäkangas, K. H., Bennett, W. P., Alavanja, M. C. R., Welsh, J. A., Khan, M. A., Lee, A., Diasio, R., Edell, E., Bungum, A., Jang, J. S., Yang, P., Jen, J. & Harris, C. C., Jun 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 6, p. 988-992 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Identification of a novel percent mammographic density locus at 12q24

Stevens, K. N., Lindstrom, S., Scott, C. G., Thompson, D., Sellers, T. A., Wang, X., Wang, A., Atkinson, E., Rider, D. N., Eckel-passow, J. E., Varghese, J. S., Audley, T., Brown, J., Leyland, J., Luben, R. N., Warren, R. M. L., Loos, R. J. F., Wareham, N. J., Li, J., Hall, P. & 34 others, Liu, J., Eriksson, L., Czene, K., Olson, J. E., Shane pankratz, V., Fredericksen, Z., Diasio, R. B., Lee, A. M., Heit, J. A., Deandrade, M., Goode, E. L., Vierkant, R. A., Cunningham, J. M., Armasu, S. M., Weinshilboum, R., Fridley, B. L., Batzler, A., Ingle, J. N., Boyd, N. F., Paterson, A. D., Rommens, J., Martin, L. J., Hopper, J. L., Southey, M. C., Stone, J., Apicella, C., Kraft, P., Hankinson, S. E., Hazra, A., Hunter, D. J., Easton, D. F., Couch, F. J., Tamimi, R. M. & Vachon, C. M., Jul 2012, In : Human molecular genetics. 21, 14, p. 3299-3305 7 p., dds158.

Research output: Contribution to journalArticle

24 Scopus citations
2011

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptorĝ€"negative breast cancer

Haiman, C. A., Chen, G. K., Vachon, C. M., Canzian, F., Dunning, A., Millikan, R. C., Wang, X., Ademuyiwa, F., Ahmed, S., Ambrosone, C. B., Baglietto, L., Balleine, R., Bandera, E. V., Beckmann, M. W., Berg, C. D., Bernstein, L., Blomqvist, C., Blot, W. J., Brauch, H., Buring, J. E. & 110 others, Carey, L. A., Carpenter, J. E., Chang-Claude, J., Chanock, S. J., Chasman, D. I., Clarke, C. L., Cox, A., Cross, S. S., Deming, S. L., Diasio, R. B., Dimopoulos, A. M., Driver, W. R., Dünnebier, T., Durcan, L., Eccles, D., Edlund, C. K., Ekici, A. B., Fasching, P. A., Feigelson, H. S., Flesch-Janys, D., Fostira, F., Försti, A., Fountzilas, G., Gerty, S. M., Giles, G. G., Godwin, A. K., Goodfellow, P., Graham, N., Greco, D., Hamann, U., Hankinson, S. E., Hartmann, A., Hein, R., Heinz, J., Holbrook, A., Hoover, R. N., Hu, J. J., Hunter, D. J., Ingles, S. A., Irwanto, A., Ivanovich, J., John, E. M., Johnson, N., Jukkola-Vuorinen, A., Kaaks, R., Ko, Y. D., Kolonel, L. N., Konstantopoulou, I., Kosma, V. M., Kulkarni, S., Lambrechts, D., Lee, A. M., Marchand, L. L., Lesnick, T., Liu, J., Lindstrom, S., Mannermaa, A., Margolin, S., Martin, N. G., Miron, P., Montgomery, G. W., Nevanlinna, H., Nickels, S., Nyante, S., Olswold, C., Palmer, J., Pathak, H., Pectasides, D., Perou, C. M., Peto, J., Pharoah, P. D. P., Pooler, L. C., Press, M. F., Pylkäs, K., Rebbeck, T. R., Rodriguez-Gil, J. L., Rosenberg, L., Ross, E., Rüdiger, T., Silva, I. D. S., Sawyer, E., Schmidt, M. K., Schulz-Wendtland, R., Schumacher, F., Severi, G., Sheng, X., Signorello, L. B., Sinn, H. P., Stevens, K. N., Southey, M. C., Tapper, W. J., Tomlinson, I., Hogervorst, F. B. L., Wauters, E., Weaver, J., Wildiers, H., Winqvist, R., Berg, D. V. D., Wan, P., Xia, L. Y., Yannoukakos, D., Zheng, W., Ziegler, R. G., Siddiq, A., Slager, S. L., Stram, D. O., Easton, D., Kraft, P., Henderson, B. E. & Couch, F. J., Dec 2011, In : Nature Genetics. 43, 12, p. 1210-1214 5 p.

Research output: Contribution to journalArticle

216 Scopus citations

Associations of common variants at 1p11.2 and 14q24.1 (RAD51l1) with breast cancer risk and heterogeneity by tumor subtype: Findings from the Breast Cancer Association Consortium

Figueroa, J. D., Garcia-Closas, M., Humphreys, M., Platte, R., Hopper, J. L., Southey, M. C., Apicella, C., Hammet, F., Schmidt, M. K., Broeks, A., Tollenaar, R. A. E. M., Van't Veer, L. J., Fasching, P. A., Beckmann, M. W., Ekici, A. B., Strick, R., Peto, J., Silva, I. D. S., Fletcher, O., Johnson, N. & 138 others, Sawyer, E., Tomlinson, I., Kerin, M., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Bojesen, S., Flyger, H., Nordestgaard, B. G., Benítez, J., Milne, R. L., Arias, J. I., Zamora, M. P., Brenner, H., Müller, H., Arndt, V., Rahman, N., Turnbull, C., Seal, S., Renwick, A., Brauch, H., Justenhoven, C., Brüning, T., Ko, Y. D., Baisch, C., Fischer, H. P., Hamann, U., Pesch, B., Rabstein, S., Harth, V., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Dörk, T., Schürmann, P., Bremer, M., Hillemanns, P., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Bogdanova, N., Antonenkova, N., Rogov, Y. I., Karstens, J. H., Bermisheva, M., Prokofieva, D., Gantcev, S. H., Khusnutdinova, E., Lindblom, A., Margolin, S., Chenevix-Trench, G., Beesley, J., Chen, X., Bowtell, D., Chenevix-Trench, G., deFazio, A., Gertig, D., Green, A., Webb, P. M., Mannermaa, A., Kosma, V. M., Soini, Y., Kataja, V., Lambrechts, D., Yesilyurt, B. T., Chrisiaens, M. R., Peeters, S., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Couch, F., Lee, A. M., Diasio, R., Wang, X., Giles, G. G., Severi, G., Baglietto, L., Maclean, C., Offit, K., Robson, M., Joseph, V., Gaudet, M., John, E. M., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I., Knight, J. A., Mulligan, A. M., O'Malley, F. P., Brinton, L. A., Sherman, M. E., Lissowska, J., Chanock, S. J., Hooning, M., Martens, J. W. M., van den Ouweland, A. M. W., Collée, J. M., Hall, P., Czene, K., Cox, A., Brock, I. W., Reed, M. W. R., Cross, S. S., Pharoah, P., Dunning, A. M., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Shen, C. Y., Ding, S. L., Hsu, H. M., Yu, J. C., Anton-Culver, H., Ziogas, A., Ashworth, A., Swerdlow, A., Jones, M., Orr, N., Trentham-Dietz, A., Egan, K., Newcomb, P., Titus-Ernstoff, L., Easton, D. & Spurdle, A. B., Dec 2011, In : Human molecular genetics. 20, 23, p. 4693-4706 14 p., ddr368.

Research output: Contribution to journalArticle

59 Scopus citations

Common breast cancer susceptibility loci are associated with triple-negative breast cancer

Stevens, K. N., Vachon, C. M., Lee, A. M., Slager, S., Lesnick, T., Olswold, C., Fasching, P. A., Miron, P., Eccles, D., Carpenter, J. E., Godwin, A. K., Ambrosone, C., Winqvist, R., Brauch, H., Schmidt, M. K., Cox, A., Cross, S. S., Sawyer, E., Hartmann, A., Beckmann, M. W. & 63 others, Schulz-Wendtland, R., Ekici, A. B., Tapper, W. J., Gerty, S. M., Durcan, L., Graham, N., Hein, R., Nickels, S., Flesch-Janys, D., Heinz, J., Sinn, H. P., Konstantopoulou, I., Fostira, F., Pectasides, D., Dimopoulos, A. M., Fountzilas, G., Clarke, C. L., Balleine, R., Olson, J. E., Fredericksen, Z., Diasio, R. B., Pathak, H., Ross, E., Weaver, J. E., Rüdiger, T., Försti, A., Dünnebier, T., Ademuyiwa, F., Kulkarni, S., Pylkäs, K., Jukkola-Vuorinen, A., Ko, Y. D., Van Limbergen, E., Janssen, H., Peto, J., Fletcher, O., Giles, G. G., Baglietto, L., Verhoef, S., Tomlinson, I., Kosma, V. M., Beesley, J., Greco, D., Blomqvist, C., Irwanto, A., Liu, J., Blows, F. M., Dawson, S. J., Margolin, S., Mannermaa, A., Martin, N. G., Montgomery, G. W., Lambrechts, D., Dos Santos Silva, I., Severi, G., Hamann, U., Pharoah, P., Easton, D. F., Chang-Claude, J., Yannoukakos, D., Nevanlinna, H., Wang, X. & Couch, F. J., Oct 1 2011, In : Cancer research. 71, 19, p. 6240-6249 10 p.

Research output: Contribution to journalArticle

92 Scopus citations

Methylation of the human pendrin promoter

Lee, A., Nofziger, C., Dossena, S., Vanoni, S., Diasio, R. & Paulmichl, M., 2011, In : Cellular Physiology and Biochemistry. 28, 3, p. 397-406 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Prognostic impact of body mass index stratified by smoking status in patients with esophageal adenocarcinoma

Yoon, H. H., Lewis, M. A., Shi, Q., Khan, M., Cassivi, S. D., Diasio, R. B. & Sinicrope, F. A., Dec 1 2011, In : Journal of Clinical Oncology. 29, 34, p. 4561-4567 7 p.

Research output: Contribution to journalArticle

49 Scopus citations
2010

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

Antoniou, A. C., Wang, X., Fredericksen, Z. S., McGuffog, L., Tarrell, R., Sinilnikova, O. M., Healey, S., Morrison, J., Kartsonaki, C., Lesnick, T., Ghoussaini, M., Barrowdale, D., Peock, S., Cook, M., Oliver, C., Frost, D., Eccles, D., Evans, D. G., Eeles, R., Izatt, L. & 158 others, Chu, C., Douglas, F., Paterson, J., Stoppa-Lyonnet, D., Houdayer, C., Mazoyer, S., Giraud, S., Lasset, C., Remenieras, A., Caron, O., Hardouin, A., Berthet, P., Hogervorst, F. B. L., Rookus, M. A., Jager, A., Van Den Ouweland, A., Hoogerbrugge, N., Van Der Luijt, R. B., Meijers-Heijboer, H., G'mez García, E. B., Devilee, P., Vreeswijk, M. P. G., Lubinski, J., Jakubowska, A., Gronwald, J., Huzarski, T., Byrski, T., G'rski, B., Cybulski, C., Spurdle, A. B., Holland, H., Goldgar, D. E., John, E. M., Hopper, J. L., Southey, M., Buys, S. S., Daly, M. B., Terry, M. B., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Preisler-Adams, S., Arnold, N., Niederacher, D., Sutter, C., Domchek, S. M., Nathanson, K. L., Rebbeck, T., Blum, J. L., Piedmonte, M., Rodriguez, G. C., Wakeley, K., Boggess, J. F., Basil, J., Blank, S. V., Friedman, E., Kaufman, B., Laitman, Y., Milgrom, R., Andrulis, I. L., Glendon, G., Ozcelik, H., Kirchhoff, T., Vijai, J., Gaudet, M. M., Altshuler, D., Guiducci, C., Loman, N., Harbst, K., Rantala, J., Ehrencrona, H., Gerdes, A. M., Thomassen, M., Sunde, L., Peterlongo, P., Manoukian, S., Bonanni, B., Viel, A., Radice, P., Caldes, T., De La Hoya, M., Singer, C. F., Fink-Retter, A., Greene, M. H., Mai, P. L., Loud, J. T., Guidugli, L., Lindor, N. M., Hansen, T. V. O., Nielsen, F. C., Blanco, I., Lazaro, C., Garber, J., Ramus, S. J., Gayther, S. A., Phelan, C., Narod, S., Szabo, C. I., Benitez, J., Osorio, A., Nevanlinna, H., Heikkinen, T., Caligo, M. A., Beattie, M. S., Hamann, U., Godwin, A. K., Montagna, M., Casella, C., Neuhausen, S. L., Karlan, B. Y., Tung, N., Toland, A. E., Weitzel, J., Olopade, O., Simard, J., Soucy, P., Rubinstein, W. S., Arason, A., Rennert, G., Martin, N. G., Montgomery, G. W., Chang-Claude, J., Flesch-Janys, D., Brauch, H., Severi, G., Baglietto, L., Cox, A., Cross, S. S., Miron, P., Gerty, S. M., Tapper, W., Yannoukakos, D., Fountzilas, G., Fasching, P. A., Beckmann, M. W., Dos Santos Silva, I., Peto, J., Lambrechts, D., Paridaens, R., Rüdiger, T., Försti, A., Winqvist, R., Pylkäs, K., Diasio, R. B., Lee, A. M., Eckel-Passow, J., Vachon, C., Blows, F., Driver, K., Dunning, A., Pharoah, P. P. D., Offit, K., Pankratz, V. S., Hakonarson, H., Chenevix-Trench, G., Easton, D. F. & Couch, F. J., Oct 2010, In : Nature Genetics. 42, 10, p. 885-892 8 p.

Research output: Contribution to journalArticle

243 Scopus citations

A phase I, pharmacokinetic, and pharmacodynamic study of two schedules of vorinostat in combination with 5-fluorouracil and leucovorin in patients with refractory solid tumors

Fakih, M. G., Fetterly, G., Egorin, M. J., Muindi, J. R., Espinoza-Delgado, I., Zwiebel, J. A., Litwin, A., Holleran, J. L., Wang, K. & Diasio, R. B., Jul 15 2010, In : Clinical Cancer Research. 16, 14, p. 3786-3794 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

A phase i dose-escalation study of edotecarin (J-107088) combined with infusional 5-fluorouracil and leucovorin in patients with advanced/metastatic solid tumors

Saif, M. W., Sellers, S., Diasio, R. B. & Douillard, J. Y., Aug 1 2010, In : Anti-cancer drugs. 21, 7, p. 716-723 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

The prognostic value of clinical and pathologic factors in esophageal adenocarcinoma: A Mayo cohort of 796 patients with extended follow-up after surgical resection

Yoon, H. H., Khan, M., Shi, Q., Cassivi, S. D., Wu, T. T., Quevedo, J. F., Burch, P. A., Sinicrope, F. A. & Diasio, R. B., Dec 2010, In : Mayo Clinic proceedings. 85, 12, p. 1080-1089 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
2009

13C-5-FU breath test current status and future directions: A comprehensive review

Ezzeldin, H. H., Acosta, E. P., Mattison, L. K., Fourie, J., Modak, A. & Diasio, R. B., Dec 25 2009, In : Journal of Breath Research. 3, 4, 047002.

Research output: Contribution to journalArticle

11 Scopus citations
10 Scopus citations
2008

Capecitabine-related cardiotoxicity: Recognition and management

Wasif Saif, M., Tomita, M., Ledbetter, L. & Diasio, R. B., Jan 1 2008, In : Journal of Supportive Oncology. 6, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Genetic regulation of β-ureidopropionase and its possible implication in altered uracil catabolism

Thomas, H. R., Ezzeldin, H. H., Guarcello, V., Mattison, L. K., Fridley, B. L. & Diasio, R. B., Jan 1 2008, In : Pharmacogenetics and genomics. 18, 1, p. 25-35 11 p.

Research output: Contribution to journalArticle

26 Scopus citations