• 4914 Citations
  • 38 Scopus h-Index
1984 …2019

Research output per year

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Research Output

Article

Murine epidermal Langerhans cells and splenic dendritic cells present tumor‐associated antigens to primed T cells

Cohen, P. J., Cohen, P. A., Rosenberg, S. A., Mulé, J. J. & Katz, S. I., Feb 1994, In : European Journal of Immunology. 24, 2, p. 315-319 5 p.

Research output: Contribution to journalArticle

108 Scopus citations

Myeloid-derived suppressor cells adhere to physiologic STAT3-vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape

Cohen, P. A., Ko, J. S., Storkus, W. J., Spencer, C. D., Bradley, J. M., Gorman, J. E., McCurry, D. B., Zorro-Manrique, S., Dominguez, A. L., Pathangey, L. B., Rayman, P. A., Rini, B. I., Gendler, S. J. & Finke, J. H., Aug 1 2012, In : Immunological Investigations. 41, 6-7, p. 680-710 31 p.

Research output: Contribution to journalArticle

29 Scopus citations

Myeloid-derived suppressor cell subset accumulation in renal cell carcinoma parenchyma is associated with intratumoral expression of IL1b, IL8, CXCL5, and Mip-1α

Najjar, Y. G., Rayman, P., Jia, X., Pavicic, P. G., Rini, B. I., Tannenbaum, C., Ko, J., Haywood, S., Cohen, P. A., Hamilton, T., Diaz-Montero, C. M. & Finke, J., May 1 2017, In : Clinical Cancer Research. 23, 9, p. 2346-2355 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Paired toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12

Zheng, R., Cohen, P. A., Paustian, C. A., Johnson, T. D., Lee, W. T., Shu, S. & Koski, G. K., Jun 1 2008, In : Cancer research. 68, 11, p. 4045-4049 5 p.

Research output: Contribution to journalArticle

43 Scopus citations

Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism

Xu, S., Koski, G. K., Faries, M., Bedrosian, I., Mick, R., Maeurer, M., Cheever, M. A., Cohen, P. A. & Czerniecki, B. J., Sep 1 2003, In : Journal of Immunology. 171, 5, p. 2251-2261 11 p.

Research output: Contribution to journalArticle

Open Access
118 Scopus citations

STAT3-And STAT5-dependent pathways competitively regulate the pan-differentiation of CD34 pos cells into tumor-competent dendritic cells

Cohen, P. A., Koski, G. K., Czerniecki, B. J., Bunting, K. D., Fu, X. Y., Wang, Z., Zhang, W. J., Carter, C. S., Awad, M., Distel, C. A., Nagem, H., Paustian, C. C., Johnson, T. D., Tisdale, J. F. & Shu, S., Sep 1 2008, In : Blood. 112, 5, p. 1832-1843 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination

Bose, A., Taylor, J. L., Alber, S., Watkins, S. C., Garcia, J. A., Rini, B. I., Ko, J. S., Cohen, P. A., Finke, J. H. & Storkus, W. J., Nov 1 2011, In : International Journal of Cancer. 129, 9, p. 2158-2170 13 p.

Research output: Contribution to journalArticle

96 Scopus citations

Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients

Ko, J. S., Zea, A. H., Rini, B. I., Ireland, J. L., Elson, P., Cohen, P., Golshayan, A., Rayman, P. A., Wood, L., Garcia, J., Dreicer, R., Bukowski, R. & Finke, J. H., Mar 15 2009, In : Clinical Cancer Research. 15, 6, p. 2148-2157 10 p.

Research output: Contribution to journalArticle

584 Scopus citations

Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens

Pathangey, L. B., McCurry, D. B., Gendler, S. J., Dominguez, A. L., Gorman, J. E., Pathangey, G., Mihalik, L. A., Dang, Y., Disis, M. L. & Cohen, P. A., Jan 1 2017, In : Oncotarget. 8, 7, p. 10785-10808 24 p.

Research output: Contribution to journalArticle

5 Scopus citations

Synthesis and Immunological Evaluation of a Multicomponent Cancer Vaccine Candidate Containing a Long MUC1 Glycopeptide

Supekar, N. T., Lakshminarayanan, V., Capicciotti, C. J., Sirohiwal, A., Madsen, C. S., Wolfert, M. A., Cohen, P. A., Gendler, S. J. & Boons, G. J., Jan 1 2017, (Accepted/In press) In : ChemBioChem.

Research output: Contribution to journalArticle

2 Scopus citations

Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion

Czerniecki, B. J., Koski, G. K., Koldovsky, U., Xu, S., Cohen, P. A., Mick, R., Nisenbaum, H., Pasha, T., Xu, M., Fox, K. R., Weinstein, S., Orel, S. G., Vonderheide, R., Coukos, G., DeMichele, A., Araujo, L., Spitz, F. R., Rosen, M., Levine, B. L., June, C. & 1 others, Zhang, P. J., Feb 15 2007, In : Cancer research. 67, 4, p. 1842-1852 11 p.

Research output: Contribution to journalArticle

191 Scopus citations

Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment

Weinstein, A. M., Chen, L., Brzana, E. A., Patil, P. R., Taylor, J. L., Fabian, K. L., Wallace, C. T., Jones, S. D., Watkins, S. C., Lu, B., Stroncek, D. F., Denning, T. L., Fu, Y. X., Cohen, P. A. & Storkus, W. J., Jun 3 2017, In : OncoImmunology. 6, 6, e1322238.

Research output: Contribution to journalArticle

13 Scopus citations

T cell adoptive immunotherapy of newly diagnosed gliomas

Plautz, G. E., Miller, D. W., Barnett, G. H., Stevens, G. H. J., Maffett, S., Kim, J., Cohen, P. A. & Shu, S., Jun 1 2000, In : Clinical Cancer Research. 6, 6, p. 2209-2218 10 p.

Research output: Contribution to journalArticle

136 Scopus citations

T-cell adoptive therapy of tumors: Mechanisms of improved therapeutic performance

Peng, L., Cohen, P. A., Kjaergaard, J., Plautz, G. E., Finke, J. H., Koski, G. K., Czerniecki, B. J. & Shu, S., Oct 23 2001, In : Critical reviews in immunology. 21, 1-3, p. 215-248 34 p.

Research output: Contribution to journalArticle

48 Scopus citations

T cell-mediated tumor rejection displays diverse dependence upon perforin and IFN-γ mechanisms that cannot be predicted from in vitro T cell characteristics

Peng, L., Krauss, J. C., Plautz, G. E., Mukai, S., Shu, S. & Cohen, P. A., Dec 15 2000, In : Journal of Immunology. 165, 12, p. 7116-7124 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Therapeutic efficacy of adoptive immunotherapy is predicated on in vivo antigen-specific proliferation of donor T cells

Kjaergaard, J., Peng, L., Cohen, P. A. & Shu, S., Jul 1 2003, In : Clinical Immunology. 108, 1, p. 8-20 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Therapeutic vaccine generated by electrofusion of dendritic cells and tumour cells.

Kuriyama, H., Shimizu, K., Lee, W., Kjaergaard, J., Parkhurst, M. R., Cohen, P. A. & Shu, S., 2004, In : Developments in biologicals. 116, p. 169-178; discussion 179-186

Research output: Contribution to journalArticle

15 Scopus citations

Toll-like receptor agonists as third signals for dendritic cell-tumor fusion vaccines

Cho, E. I., Tan, C., Koski, G. K., Cohen, P. A., Shu, S. & Lee, W. T., Jun 1 2010, In : Head and Neck. 32, 6, p. 700-707 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Treatment of established lung metastases with tumor-infiltrating lymphocytes derived from a poorly immunogenic tumor engineered to secrete human TNF-α

Marincola, F. M., Ettinghausen, S., Cohen, P. A., Cheshire, L. B., Restifo, N. P., Mule, J. J. & Rosenberg, S. A., Apr 1 1994, In : Journal of Immunology. 152, 7, p. 3501-3513 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

Tumor-induced CD11b+Gr-1+ myeloid cells suppress T cell sensitization in tumor-draining lymph nodes

Watanabe, S., Deguchi, K., Zheng, R., Tamai, H., Wang, L. X., Cohen, P. A. & Shu, S., Sep 1 2008, In : Journal of Immunology. 181, 5, p. 3291-3300 10 p.

Research output: Contribution to journalArticle

Open Access
90 Scopus citations

Tumor-induced L-selectinhigh suppressor T cells mediate potent effector T cell blockade and cause failure of otherwise curative adoptive immunotherapy

Peng, L., Kjaergäard, J., Plautz, G. E., Awad, M., Drazba, J. A., Shu, S. & Cohen, P. A., Nov 1 2002, In : Journal of Immunology. 169, 9, p. 4811-4821 11 p.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

Use of interleukin-7, interleukin-2, and interferon-γ to propagate CD4+T cells in culture with maintained antigen specificity

Cohen, P. A., Kim, H., Fowler, D. H., Gress, R. E., Jakobsen, M. K., Alexander, R. B., Mulé, J. J., Carter, C. & Rosenberg, S. A., Oct 1993, In : Journal of Immunotherapy. 14, 3, 1 p.

Research output: Contribution to journalArticle

26 Scopus citations

Vaccines targeting tumor blood vessel antigens promote CD8 + T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice

Zhao, X., Bose, A., Komita, H., Taylor, J. L., Chi, N., Lowe, D. B., Okada, H., Cao, Y., Mukhopadhyay, D., Cohen, P. A. & Storkus, W. J., Feb 15 2012, In : Journal of Immunology. 188, 4, p. 1782-1788 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
Chapter

Interferons and interleukin-2: Molecular basis of activity and therapeutic results

Hutson, T. E., Thakkar, S., Cohen, P. & Borden, E. C., Dec 1 2009, Renal Cell Carcinoma: Molecular Targets and Clinical Applications. Humana Press, p. 49-78 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
Comment/debate

Erratum: Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species (Journal of Clinical Investigation (2000) 105 (1095-1108))

Podrez, E. A., Febbraio, M., Sheibani, N., Schmitt, D., Silverstein, R. L., Hajjar, D. P., Cohen, P. A., Frazier, W. A., Hoff, H. F. & Hazen, S. L., Jun 8 2000, In : Journal of Clinical Investigation. 105, 10, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
Editorial

Tumor-Dendritic Cell Fusion Technology and Immunotherapy Strategies

Shu, S. & Cohen, P., Jan 1 2001, In : Journal of Immunotherapy. 24, 2, p. 99-100 2 p.

Research output: Contribution to journalEditorial

20 Scopus citations
Review article

CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection

Cohen, P. A., Peng, L., Plautz, G. E., Kim, J. A., Weng, D. E. & Shu, S., Apr 18 2000, In : Critical reviews in immunology. 20, 1, p. 17-56 40 p.

Research output: Contribution to journalReview article

95 Scopus citations

Considerations on clinical use of T cell immunotherapy for cancer

Plautz, G. E., Cohen, P. A. & Shu, S., Sep 5 2003, In : Archivum Immunologiae et Therapiae Experimentalis. 51, 4, p. 245-257 13 p.

Research output: Contribution to journalReview article

10 Scopus citations

Immunogenicity of dendritic-tumor fusion hybrids and their utility in cancer immunotherapy

Shu, S., Zheng, R., Lee, W. T. & Cohen, P. A., Dec 1 2007, In : Critical reviews in immunology. 27, 5, p. 463-483 21 p.

Research output: Contribution to journalReview article

24 Scopus citations

Improving immunotherapy by conditionally enhancing MHC class I presentation of tumor antigen-derived peptide epitopes

Storkus, W. J., Herrem, C., Kawabe, M., Cohen, P. A., Bukowski, R. M., Finke, J. H. & Wesa, A. K., Dec 1 2007, In : Critical reviews in immunology. 27, 5, p. 485-493 9 p.

Research output: Contribution to journalReview article

11 Scopus citations

Modification of the tumor microenvironment as a novel target of renal cell carcinoma therapeutics

Finke, J. H., Rayman, P. A., Ko, J. S., Bradley, J. M., Gendler, S. J. & Cohen, P. A., Jul 1 2013, In : Cancer Journal (United States). 19, 4, p. 353-364 12 p.

Research output: Contribution to journalReview article

31 Scopus citations

Propagation of mouse and human T cells with defined antigen specificity and function.

Cohen, P. A., Fowler, D. H., Kim, H., White, R. L., Czerniecki, B. J., Carter, C., Gress, R. E. & Rosenberg, S. A., 1994, In : Ciba Foundation symposium. 187, p. 179-193; discussion 194-197

Research output: Contribution to journalReview article

9 Scopus citations

Reengineering dendritic cell-based anti-cancer vaccines

Koski, G. K., Cohen, P. A., Roses, R. E., Xu, S. & Czerniecki, B. J., Apr 1 2008, In : Immunological Reviews. 222, 1, p. 256-276 21 p.

Research output: Contribution to journalReview article

49 Scopus citations

Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy.

Zheng, R., Kjaergaard, J., Lee, W. T., Cohen, P. A. & Shu, S., 2007, In : Cancer treatment and research. 135, p. 223-237 15 p.

Research output: Contribution to journalReview article

9 Scopus citations