• 4709 Citations
  • 36 Scopus h-Index
1984 …2019
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Research Output 1984 2017

  • 4709 Citations
  • 36 Scopus h-Index
  • 85 Article
  • 1 Chapter
2017
2 Citations (Scopus)

Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet

Myers, C. E., Hoelzinger, D. B., Truong, T. N., Chew, L. A., Myles, A., Chaudhuri, L., Egan, J. B., Liu, J. D., Gendler, S. J. & Cohen, P. A., 2017, In : Oncotarget. 8, 3, p. 5426-5438 13 p.

Research output: Contribution to journalArticle

Obese Mice
High Fat Diet
Methotrexate
Weight Loss
Eating
23 Citations (Scopus)

Myeloid-derived suppressor cell subset accumulation in renal cell carcinoma parenchyma is associated with intratumoral expression of IL1b, IL8, CXCL5, and Mip-1α

Najjar, Y. G., Rayman, P., Jia, X., Pavicic, P. G., Rini, B. I., Tannenbaum, C., Ko, J., Haywood, S., Cohen, P. A., Hamilton, T., Diaz-Montero, C. M. & Finke, J., May 1 2017, In : Clinical Cancer Research. 23, 9, p. 2346-2355 10 p.

Research output: Contribution to journalArticle

Interleukin-8
Renal Cell Carcinoma
Neoplasms
Myeloid-Derived Suppressor Cells
Tumor Burden
5 Citations (Scopus)

Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens

Pathangey, L. B., McCurry, D. B., Gendler, S. J., Dominguez, A. L., Gorman, J. E., Pathangey, G., Mihalik, L. A., Dang, Y., Disis, M. L. & Cohen, P. A., 2017, In : Oncotarget. 8, 7, p. 10785-10808 24 p.

Research output: Contribution to journalArticle

Interleukin-7
Neoplasm Antigens
Innate Immunity
Blood Cells
T-Lymphocytes
1 Citation (Scopus)

Synthesis and Immunological Evaluation of a Multicomponent Cancer Vaccine Candidate Containing a Long MUC1 Glycopeptide

Supekar, N. T., Lakshminarayanan, V., Capicciotti, C. J., Sirohiwal, A., Madsen, C. S., Wolfert, M. A., Cohen, P. A., Gendler, S. J. & Boons, G. J., Jan 1 2017, (Accepted/In press) In : ChemBioChem.

Research output: Contribution to journalArticle

Cancer Vaccines
Glycopeptides
T-cells
Epitopes
Tumors
8 Citations (Scopus)

Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment

Weinstein, A. M., Chen, L., Brzana, E. A., Patil, P. R., Taylor, J. L., Fabian, K. L., Wallace, C. T., Jones, S. D., Watkins, S. C., Lu, B., Stroncek, D. F., Denning, T. L., Fu, Y. X., Cohen, P. A. & Storkus, W. J., Jun 3 2017, In : OncoImmunology. 6, 6, e1322238.

Research output: Contribution to journalArticle

Tumor Microenvironment
Organogenesis
Dendritic Cells
Therapeutics
Neoplasms
2016
9 Citations (Scopus)

Definitive activation of endogenous antitumor immunity by repetitive cycles of cyclophosphamide with interspersed Tolllike receptor agonists

Manrique, S. Z., Dominguez, A. L., Mirza, N., Spencer, C. D., Bradley, J. M., Finke, J. H., Lee, J. J., Pease, L. R., Gendler, S. J. & Cohen, P. A., 2016, In : Oncotarget. 7, 28, p. 42919-42942 24 p.

Research output: Contribution to journalArticle

Cyclophosphamide
Immunity
Toll-Like Receptors
Neoplasms
T-Lymphocytes
18 Citations (Scopus)

MUC1 vaccines, comprised of glycosylated or non-glycosylated peptides or tumor-derived MUC1, can circumvent immunoediting to control tumor growth in MUC1 transgenic mice

Lakshminarayanan, V., Supekar, N. T., Wei, J., McCurry, D. B., Dueck, A., Kosiorek, H. E., Trivedi, P. P., Bradley, J. M., Madsen, C. S., Pathangey, L. B., Hoelzinger, D. B., Wolfert, M. A., Boons, G. J., Cohen, P. A. & Gendler, S. J., Jan 1 2016, In : PLoS One. 11, 1, e0145920.

Research output: Contribution to journalArticle

Transgenic Mice
Tumors
Vaccines
genetically modified organisms
peptides
2015
13 Citations (Scopus)

Late-stage cancer patients remain highly responsive to immune activation by the selective TLR8 agonist motolimod (VTX-2337)

Dietsch, G. N., Randall, T. D., Gottardo, R., Northfelt, D. W., Ramanathan, R. K., Cohen, P. A., Manjarrez, K. L., Newkirk, M., Bryan, J. K. & Hershberg, R. M., Dec 15 2015, In : Clinical Cancer Research. 21, 24, p. 5445-5452 8 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 8
Neoplasms
Healthy Volunteers
Pharmacokinetics
Biomarkers
20 Citations (Scopus)

Linear synthesis and immunological properties of a fully synthetic vaccine candidate containing a sialylated MUC1 glycopeptide

Thompson, P., Lakshminarayanan, V., Supekar, N. T., Bradley, J. M., Cohen, P. A., Wolfert, M. A., Gendler, S. J. & Boons, G. J., May 28 2015, In : Chemical Communications. 51, 50, p. 10214-10217 4 p.

Research output: Contribution to journalArticle

Synthetic Vaccines
Vaccines
Glycopeptides
Cancer Vaccines
T-cells
2014
85 Citations (Scopus)

Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma

Chodon, T., Comin-Anduix, B., Chmielowski, B., Koya, R. C., Wu, Z., Auerbach, M., Ng, C., Avramis, E., Seja, E., Villanueva, A., McCannel, T. A., Ishiyama, A., Czernin, J., Radu, C. G., Wang, X., Gjertson, D. W., Cochran, A. J., Cornetta, K., Wong, D. J. L., Kaplan-Lefko, P. & 14 others, Hamid, O., Samlowski, W., Cohen, P. A., Daniels, G. A., Mukherji, B., Yang, L., Zack, J. A., Kohn, D. B., Heath, J. R., Glaspy, J. A., Witte, O. N., Baltimore, D., Economou, J. S. & Ribas, A., May 1 2014, In : Clinical Cancer Research. 20, 9, p. 2457-2465 9 p.

Research output: Contribution to journalArticle

Adoptive Transfer
T-Cell Antigen Receptor
Dendritic Cells
Melanoma
Vaccination
24 Citations (Scopus)

A phase I dose-finding study of the novel toll-like receptor 8 agonist VTX-2337 in adult subjects with advanced solid tumors or lymphoma

Northfelt, D. W., Ramanathan, R. K., Cohen, P. A., Von Hoff, D. D., Weiss, G. J., Dietsch, G. N., Manjarrez, K. L., Randall, T. D. & Hershberg, R. M., Jul 15 2014, In : Clinical Cancer Research. 20, 14, p. 3683-3691 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 8
Lymphoma
Maximum Tolerated Dose
Pharmacokinetics
Neoplasms
21 Citations (Scopus)

Combination of sunitinib with anti-tumor vaccination inhibits T cell priming and requires careful scheduling to achieve productive immunotherapy

Jaini, R., Rayman, P., Cohen, P. A., Finke, J. H. & Tuohy, V. K., Apr 1 2014, In : International Journal of Cancer. 134, 7, p. 1695-1705 11 p.

Research output: Contribution to journalArticle

Immunotherapy
Vaccination
T-Lymphocytes
Lactalbumin
Neoplasms
31 Citations (Scopus)

Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist

Abdel-Aal, A. B. M., Lakshminarayanan, V., Thompson, P., Supekar, N., Bradley, J. M., Wolfert, M. A., Cohen, P. A., Gendler, S. J. & Boons, G. J., Jul 7 2014, In : ChemBioChem. 15, 10, p. 1508-1513 6 p.

Research output: Contribution to journalArticle

T-cells
Tumors
Vaccines
Glycopeptides
Cytotoxic T-Lymphocytes
14 Citations (Scopus)

Inhibition of adaptive immunity by IL9 can be disrupted to achieve rapid t-cell sensitization and rejection of progressive tumor challenges

Hoelzinger, D. B., Dominguez, A. L., Cohen, P. A. & Gendler, S. J., Dec 1 2014, In : Cancer Research. 74, 23, p. 6845-6855 11 p.

Research output: Contribution to journalArticle

Interleukin-9
Adaptive Immunity
Neoplasms
Immunologic Memory
T-Lymphocytes
2013
53 Citations (Scopus)

A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma: A North Central Cancer Treatment Group study, N0775

Kottschade, L. A., Suman, V. J., Perez, D. G., Mc Williams, R. R., Kaur, J. S., Amatruda, T. T., Geoffroy, F. J., Gross, H. M., Cohen, P. A., Jaslowski, A. J., Kosel, M. L. & Markovic, S. N., Feb 1 2013, In : Cancer. 119, 3, p. 586-592 7 p.

Research output: Contribution to journalArticle

temozolomide
Carboplatin
Melanoma
Neoplasms
Area Under Curve
8 Citations (Scopus)

Downregulation of hematopoietic MUC1 during Experimental colitis increases tumor-promoting myeloid-derived suppressor cells

Poh, T. W., Madsen, C. S., Gorman, J. E., Marler, R. J., Leighton, J. A., Cohen, P. A. & Gendler, S. J., Sep 15 2013, In : Clinical Cancer Research. 19, 18, p. 5039-5052 14 p.

Research output: Contribution to journalArticle

Colitis
Down-Regulation
Neoplasms
Inflammatory Bowel Diseases
Colon
18 Citations (Scopus)

Extracellular ATP and Toll-Like Receptor 2 Agonists Trigger in Human Monocytes an Activation Program That Favors T Helper 17

Paustian, C., Taylor, P., Johnson, T., Xu, M., Ramirez, N., Rosenthal, K. S., Shu, S., Cohen, P. A., Czerniecki, B. J. & Koski, G. K., Jan 31 2013, In : PLoS One. 8, 1, e54804.

Research output: Contribution to journalArticle

Toll-Like Receptor 2
adenosine triphosphate
Interleukin-23
monocytes
agonists
27 Citations (Scopus)

Modification of the tumor microenvironment as a novel target of renal cell carcinoma therapeutics

Finke, J. H., Rayman, P. A., Ko, J. S., Bradley, J. M., Gendler, S. J. & Cohen, P. A., Jul 2013, In : Cancer Journal (United States). 19, 4, p. 353-364 12 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Renal Cell Carcinoma
Receptor Protein-Tyrosine Kinases
Immunotherapy
Therapeutics
2012
187 Citations (Scopus)

Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

Lakshminarayanan, V., Thompson, P., Wolfert, M. A., Buskas, T., Bradley, J. M., Pathangey, L. B., Madsen, C. S., Cohen, P. A., Gendler, S. J. & Boons, G. J., Jan 3 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 1, p. 261-266 6 p.

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
Mucins
Vaccines
Antibody-Dependent Cell Cytotoxicity
Peptides
27 Citations (Scopus)

Myeloid-derived suppressor cells adhere to physiologic STAT3-vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape

Cohen, P. A., Ko, J. S., Storkus, W. J., Spencer, C. D., Bradley, J. M., Gorman, J. E., McCurry, D. B., Zorro-Manrique, S., Dominguez, A. L., Pathangey, L. B., Rayman, P. A., Rini, B. I., Gendler, S. J. & Finke, J. H., Aug 2012, In : Immunological Investigations. 41, 6-7, p. 680-710 31 p.

Research output: Contribution to journalArticle

Neoplasms
Granulocyte-Macrophage Colony-Stimulating Factor
T-Lymphocytes
Myeloid-Derived Suppressor Cells
Receptor Protein-Tyrosine Kinases
26 Citations (Scopus)

Vaccines targeting tumor blood vessel antigens promote CD8 + T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice

Zhao, X., Bose, A., Komita, H., Taylor, J. L., Chi, N., Lowe, D. B., Okada, H., Cao, Y., Mukhopadhyay, D., Cohen, P. A. & Storkus, W. J., Feb 15 2012, In : Journal of Immunology. 188, 4, p. 1782-1788 7 p.

Research output: Contribution to journalArticle

Vascular Tissue Neoplasms
CD8 Antigens
HLA-A2 Antigen
Transgenic Mice
Vaccines
2011
21 Citations (Scopus)

Effect of multiple activation stimuli on the generation of Th1-polarizing dendritic cells

Paustian, C., Caspell, R., Johnson, T., Cohen, P. A., Shu, S., Xu, S., Czerniecki, B. J. & Koski, G. K., Jan 2011, In : Human Immunology. 72, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

Interleukin-12
Dendritic Cells
resiquimod
Interferons
CD40 Ligand
166 Citations (Scopus)

MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy

Finke, J., Ko, J., Rini, B., Rayman, P., Ireland, J. & Cohen, P. A., Jul 2011, In : International Immunopharmacology. 11, 7, p. 853-858 6 p.

Research output: Contribution to journalArticle

Tumor Escape
T-Lymphocytes
Therapeutics
Neoplasms
Granulocyte-Macrophage Colony-Stimulating Factor

MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy.

Finke, J., Ko, J., Rini, B., Rayman, P., Ireland, J. & Cohen, P., Jul 2011, In : International Immunopharmacology. 11, 7, p. 856-861 6 p.

Research output: Contribution to journalArticle

Tumor Escape
T-Lymphocytes
Therapeutics
Neoplasms
Granulocyte-Macrophage Colony-Stimulating Factor
92 Citations (Scopus)

Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination

Bose, A., Taylor, J. L., Alber, S., Watkins, S. C., Garcia, J. A., Rini, B. I., Ko, J. S., Cohen, P. A., Finke, J. H. & Storkus, W. J., Nov 1 2011, In : International Journal of Cancer. 129, 9, p. 2158-2170 13 p.

Research output: Contribution to journalArticle

Immunity
Vaccination
Tumor Microenvironment
Ovalbumin
Vaccines
2010
187 Citations (Scopus)

Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained

Ko, J. S., Rayman, P., Ireland, J., Swaidani, S., Li, G., Bunting, K. D., Rini, B., Finke, J. H. & Cohen, P. A., May 1 2010, In : Cancer Research. 70, 9, p. 3526-3536 11 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Renal Cell Carcinoma
Neoplasms
Immunologic Factors
T-Lymphocytes
3 Citations (Scopus)

Immunotherapy using allogeneic squamous cell tumor-dendritic cell fusion hybrids

Lee, W. T., Tan, C., Koski, G., Shu, S. & Cohen, P. A., Sep 2010, In : Head and Neck. 32, 9, p. 1209-1216 8 p.

Research output: Contribution to journalArticle

Cell Fusion
Immunotherapy
Dendritic Cells
Epithelial Cells
Neoplasms
15 Citations (Scopus)

J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells

Taylor, P. R., Koski, G. K., Paustian, C. C., Bailey, E., Cohen, P. A., Moore, F. B. G., Zimmerman, D. H. & Rosenthal, K. S., Aug 2010, In : Vaccine. 28, 34, p. 5533-5542 10 p.

Research output: Contribution to journalArticle

antigen presentation
Antigen Presentation
dendritic cells
Dendritic Cells
epitopes
11 Citations (Scopus)

Toll-like receptor agonists as third signals for dendritic cell-tumor fusion vaccines

Cho, E. I., Tan, C., Koski, G. K., Cohen, P. A., Shu, S. & Lee, W. T., Jun 2010, In : Head and Neck. 32, 6, p. 700-707 8 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Cell Fusion
Toll-Like Receptors
Dendritic Cells
Neoplasm Metastasis
2009
1 Citation (Scopus)

Interferons and interleukin-2: Molecular basis of activity and therapeutic results

Hutson, T. E., Thakkar, S., Cohen, P. A. & Borden, E. C., 2009, Renal Cell Carcinoma: Molecular Targets and Clinical Applications. Humana Press, p. 49-78 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Renal Cell Carcinoma
Interferons
Interleukin-2
Cytokines
Therapeutics
556 Citations (Scopus)

Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients

Ko, J. S., Zea, A. H., Rini, B. I., Ireland, J. L., Elson, P., Cohen, P. A., Golshayan, A., Rayman, P. A., Wood, L., Garcia, J., Dreicer, R., Bukowski, R. & Finke, J. H., Mar 15 2009, In : Clinical Cancer Research. 15, 6, p. 2148-2157 10 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
T-Lymphocytes
Regulatory T-Lymphocytes
sunitinib
Myeloid-Derived Suppressor Cells
2008
23 Citations (Scopus)

Effective treatment of spontaneous metastases derived from a poorly immunogenic murine mammary carcinoma by combined dendritic-tumor hybrid vaccination and adoptive transfer of sensitized T cells

Tamai, H., Watanabe, S., Zheng, R., Deguchi, K., Cohen, P. A., Koski, G. K. & Shu, S., Apr 2008, In : Clinical Immunology. 127, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

Adoptive Transfer
Vaccination
Breast Neoplasms
Neoplasm Metastasis
T-Lymphocytes
5 Citations (Scopus)

Immunotherapy of established murine squamous cell carcinoma using fused dendritic-tumor cell hybrids

Lee, W. T., Tamai, H., Cohen, P. A., Teker, A. M. & Shu, S., Jun 2008, In : Archives of Otolaryngology - Head and Neck Surgery. 134, 6, p. 608-613 6 p.

Research output: Contribution to journalArticle

Immunotherapy
Dendritic Cells
Squamous Cell Carcinoma
Cell Fusion
Neoplasms
43 Citations (Scopus)

Paired toll-like receptor agonists enhance vaccine therapy through induction of interleukin-12

Zheng, R., Cohen, P. A., Paustian, C. A., Johnson, T. D., Lee, W. T., Shu, S. & Koski, G. K., Jun 1 2008, In : Cancer Research. 68, 11, p. 4045-4049 5 p.

Research output: Contribution to journalArticle

Active Immunotherapy
Toll-Like Receptors
Interleukin-12
Therapeutic Uses
Dendritic Cells
45 Citations (Scopus)

Reengineering dendritic cell-based anti-cancer vaccines

Koski, G. K., Cohen, P. A., Roses, R. E., Xu, S. & Czerniecki, B. J., Apr 2008, In : Immunological Reviews. 222, 1, p. 256-276 21 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Dendritic Cells
Vaccines
Antibody-Producing Cells
Cytotoxic T-Lymphocytes
35 Citations (Scopus)

STAT3-And STAT5-dependent pathways competitively regulate the pan-differentiation of CD34 pos cells into tumor-competent dendritic cells

Cohen, P. A., Koski, G. K., Czerniecki, B. J., Bunting, K. D., Fu, X. Y., Wang, Z., Zhang, W. J., Carter, C. S., Awad, M., Distel, C. A., Nagem, H., Paustian, C. C., Johnson, T. D., Tisdale, J. F. & Shu, S., Sep 1 2008, In : Blood. 112, 5, p. 1832-1843 12 p.

Research output: Contribution to journalArticle

Dendritic Cells
Tumors
Granulocyte-Macrophage Colony-Stimulating Factor
Polarization
Interleukin-6
85 Citations (Scopus)

Tumor-induced CD11b+Gr-1+ myeloid cells suppress T cell sensitization in tumor-draining lymph nodes

Watanabe, S., Deguchi, K., Zheng, R., Tamai, H., Wang, L. X., Cohen, P. A. & Shu, S., Sep 1 2008, In : Journal of Immunology. 181, 5, p. 3291-3300 10 p.

Research output: Contribution to journalArticle

Myeloid Cells
Lymph Nodes
T-Lymphocytes
Neoplasms
Spleen
2007
24 Citations (Scopus)

Immunogenicity of dendritic-tumor fusion hybrids and their utility in cancer immunotherapy

Shu, S., Zheng, R., Lee, W. T. & Cohen, P. A., 2007, In : Critical Reviews in Immunology. 27, 5, p. 463-483 21 p.

Research output: Contribution to journalArticle

Immunotherapy
Dendritic Cells
Neoplasms
Cell Fusion
Neoplasm Antigens
10 Citations (Scopus)

Improving immunotherapy by conditionally enhancing MHC class I presentation of tumor antigen-derived peptide epitopes

Storkus, W. J., Herrem, C., Kawabe, M., Cohen, P. A., Bukowski, R. M., Finke, J. H. & Wesa, A. K., 2007, In : Critical Reviews in Immunology. 27, 5, p. 485-493 9 p.

Research output: Contribution to journalArticle

Histocompatibility
Neoplasm Antigens
Immunotherapy
Epitopes
Peptides
8 Citations (Scopus)

Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy.

Zheng, R., Kjaergaard, J., Lee, W. T., Cohen, P. A. & Shu, S., 2007, In : Cancer Treatment and Research. 135, p. 223-237 15 p.

Research output: Contribution to journalArticle

Immune Tolerance
Cancer Vaccines
Cell Transplantation
Neoplasm Antigens
Immunotherapy
184 Citations (Scopus)

Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion

Czerniecki, B. J., Koski, G. K., Koldovsky, U., Xu, S., Cohen, P. A., Mick, R., Nisenbaum, H., Pasha, T., Xu, M., Fox, K. R., Weinstein, S., Orel, S. G., Vonderheide, R., Coukos, G., DeMichele, A., Araujo, L., Spitz, F. R., Rosen, M., Levine, B. L., June, C. & 1 others, Zhang, P. J., Feb 15 2007, In : Cancer Research. 67, 4, p. 1842-1852 11 p.

Research output: Contribution to journalArticle

Interleukin-12
Dendritic Cells
Vaccination
Carcinoma, Intraductal, Noninfiltrating
Breast Neoplasms
2006
20 Citations (Scopus)

Mechanism of third signals provided by IL-12 and OX-40R ligation in eliciting therapeutic immunity following dendritic-tumor fusion vaccination

Kuriyama, H., Watanabe, S., Kjaergaard, J., Tamai, H., Zheng, R., Weinberg, A. D., Hu, H. M., Cohen, P. A., Plautz, G. E. & Shu, S., 2006, In : Cellular Immunology. 243, 1, p. 30-40 11 p.

Research output: Contribution to journalArticle

Interleukin-12
Ligation
Immunity
Vaccination
Monoclonal Antibodies
2004
22 Citations (Scopus)

Adoptive immunotherapy of cancer with polyclonal, 108-fold hyperexpanded, CD4+ and CD8+T cells

Wang, L. X., Huang, W. X., Graor, H., Cohen, P. A., Kim, J. A., Shu, S. & Plautz, G. E., Nov 26 2004, In : Journal of Translational Medicine. 2

Research output: Contribution to journalArticle

Adoptive Immunotherapy
T-cells
T-Lymphocytes
Tumors
Interleukin-7
80 Citations (Scopus)

Cutting Edge: Innate Immune System Discriminates between RNA Containing Bacterial versus Eukaryotic Structural Features That Prime for High-Level, IL-12 Secretion by Dendritic Cells

Koski, G. K., Karikó, K., Xu, S., Weissman, D., Cohen, P. A. & Czerniecki, B. J., Apr 1 2004, In : Journal of Immunology. 172, 7, p. 3989-3993 5 p.

Research output: Contribution to journalArticle

Bacterial RNA
Interleukin-12
Dendritic Cells
Immune System
RNA
21 Citations (Scopus)

Memory T Cells Originate from Adoptively Transferred Effectors and Reconstituting Host Cells after Sequential Lymphodepletion and Adoptive Immunotherapy

Wang, L. X., Kjaergaard, J., Cohen, P. A., Shu, S. & Plautz, G. E., Mar 15 2004, In : Journal of Immunology. 172, 6, p. 3462-3468 7 p.

Research output: Contribution to journalArticle

Adoptive Immunotherapy
T-Lymphocytes
Adoptive Transfer
Neoplasms
Interleukin-7
15 Citations (Scopus)

Therapeutic vaccine generated by electrofusion of dendritic cells and tumour cells.

Kuriyama, H., Shimizu, K., Lee, W., Kjaergaard, J., Parkhurst, M. R., Cohen, P. A. & Shu, S., 2004, In : Developments in Biologicals. 116

Research output: Contribution to journalArticle

Vaccines
Dendritic Cells
Tumors
Cells
Fusion reactions
2003
10 Citations (Scopus)

Considerations on clinical use of T cell immunotherapy for cancer

Plautz, G. E., Cohen, P. A. & Shu, S., 2003, In : Archivum Immunologiae et Therapiae Experimentalis. 51, 4, p. 245-257 13 p.

Research output: Contribution to journalArticle

Immunotherapy
T-Lymphocytes
Neoplasm Antigens
Dendritic Cells
Neoplasms
143 Citations (Scopus)

Intranodal administration of peptide-pulsed mature dendritic cell vaccines results in superior CD8+ T-cell function in melanoma patients

Bedrosian, I., Mick, R., Xu, S., Nisenbaum, H., Faries, M., Zhang, P., Cohen, P. A., Koski, G. & Czerniecki, B. J., Oct 15 2003, In : Journal of Clinical Oncology. 21, 20, p. 3826-3835 10 p.

Research output: Contribution to journalArticle

Dendritic Cells
Melanoma
Vaccines
T-Lymphocytes
Peptides
115 Citations (Scopus)

Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism

Xu, S., Koski, G. K., Faries, M., Bedrosian, I., Mick, R., Maeurer, M., Cheever, M. A., Cohen, P. A. & Czerniecki, B. J., Sep 1 2003, In : Journal of Immunology. 171, 5, p. 2251-2261 11 p.

Research output: Contribution to journalArticle

Neoplasm Antigens
Interleukin-12
Dendritic Cells
T-Lymphocytes
Neoplasms
17 Citations (Scopus)

Therapeutic efficacy of adoptive immunotherapy is predicated on in vivo antigen-specific proliferation of donor T cells

Kjaergaard, J., Peng, L., Cohen, P. A. & Shu, S., Jul 1 2003, In : Clinical Immunology. 108, 1, p. 8-20 13 p.

Research output: Contribution to journalArticle

Adoptive Immunotherapy
T-Lymphocytes
Antigens
Whole-Body Irradiation
Cell Proliferation