• 4878 Citations
  • 37 Scopus h-Index
1984 …2019

Research output per year

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Research Output

  • 4878 Citations
  • 37 Scopus h-Index
  • 83 Article
  • 1 Chapter
1984

Human IgE synthesis in vitro by pokeweed mitogen-stimulated human lymphoid cells: Verification with a reconfirmed ε-specific radioimmunoassay

Chen, P. P., Nonaka, M., O'Hair, C. H., Cohen, P. A., Zuraw, B. L. & Katz, D. H., 1984, In : Journal of Immunology. 133, 4, p. 1909-1913 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
1993

Use of interleukin-7, interleukin-2, and interferon-γ to propagate CD4+ T cells in culture with maintained antigen specificity

Cohen, P. A., Kim, H., Fowler, D. H., Gress, R. E., Jakobsen, M. K., Alexander, R. B., Mule, J. J., Carter, C. & Rosenberg, S. A., 1993, In : Journal of Immunotherapy. 14, 3, p. 242-252 11 p.

Research output: Contribution to journalArticle

26 Scopus citations
1994

CD4+ T-cells from mice immunized to syngeneic sarcomas recognize distinct, non-shared tumor antigens

Cohen, P. A., Cohen, P. J., Rosenberg, S. A. & Mulé, J. J., Feb 15 1994, In : Cancer Research. 54, 4, p. 1055-1058 4 p.

Research output: Contribution to journalArticle

42 Scopus citations

Cells of Th2 cytokine phenotype prevent LPS-lnduced lethality during murine graft-versus-host reaction: Regulation of cytokines and CD8+ lymphoid engraftment

Fowler, D. H., Kurasawa, K., Husebekk, A., Cohen, P. A. & Gress, R. E., Feb 1 1994, In : Journal of Immunology. 152, 3, p. 1004-1013 10 p.

Research output: Contribution to journalArticle

130 Scopus citations

Murine epidermal Langerhans cells and splenic dendritic cells present tumor-associated antigens to primed T cells

Cohen, P. J., Cohen, P. A., Rosenberg, S. A., Katz, S. I. & Mulé, J. J., Feb 1994, In : European Journal of Immunology. 24, 2, p. 315-319 5 p.

Research output: Contribution to journalArticle

108 Scopus citations

Propagation of mouse and human T cells with defined antigen specificity and function.

Cohen, P. A., Fowler, D. H., Kim, H., White, R. L., Czerniecki, B. J., Carter, C., Gress, R. E. & Rosenberg, S. A., 1994, In : Ciba Foundation symposium. 187, p. 179-193 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

Treatment of established lung metastases with tumor-infiltrating lymphocytes derived from a poorly immunogenic tumor engineered to secrete human TNF-α

Marincola, F. M., Ettinghausen, S., Cohen, P. A., Cheshire, L. B., Restifo, N. P., Mule, J. J. & Rosenberg, S. A., Apr 1 1994, In : Journal of Immunology. 152, 7, p. 3501-3513 13 p.

Research output: Contribution to journalArticle

21 Scopus citations
1995

Defective major histocompatibility complex class I expression in a sarcomatoid renal cell carcinoma cell line

Jakobsen, M. K., Restifo, N. P., Cohen, P. A., Marincola, F. M., Cheshire, L. B., Linehan, W. M., Rosenberg, S. A. & Alexander, R. B., 1995, In : Journal of Immunotherapy. 17, 4, p. 222-228 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Helper T cells infiltrating human renal cell carcinomas have the phenotype of activated memory-like T lymphocytes

Alexander, R. B., Fitzgerald, E. B., Mixon, A., Carter, C. S., Jakobsen, M., Cohen, P. A. & Rosenberg, S. A., 1995, In : Journal of Immunotherapy. 17, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

20 Scopus citations
1997

Calcium Ionophore-Treated Peripheral Blood Monocytes and Dendritic Cells Rapidly Display Characteristics of Activated Dendritic Cells

Czerniecki, B. J., Carter, C., Rivoltini, L., Koski, G. K., Kim, H. I., Weng, D. E., Roros, J. G., Hijazi, Y. M., Xu, S., Rosenberg, S. A. & Cohen, P. A., Oct 15 1997, In : Journal of Immunology. 159, 8, p. 3823-3837 15 p.

Research output: Contribution to journalArticle

162 Scopus citations
1999

Calcium ionophore-treated myeloid cells acquire many dendritic cell characteristics independent of prior differentiation state, transformation status, or sensitivity to biologic agents

Koski, G. K., Schwartz, G. N., Weng, D. E., Gress, R. E., Engels, F. H. C., Tsokos, M., Czerniecki, B. J. & Cohen, P. A., Aug 15 1999, In : Blood. 94, 4, p. 1359-1371 13 p.

Research output: Contribution to journalArticle

63 Scopus citations

Calcium mobilization in human myeloid cells results in acquisition of individual dendritic cell-like characteristics through discrete signaling pathways

Koski, G. K., Schwartz, G. N., Weng, D. E., Czerniecki, B. J., Carter, C., Gress, R. E. & Cohen, P. A., Jul 1 1999, In : Journal of Immunology. 163, 1, p. 82-92 11 p.

Research output: Contribution to journalArticle

84 Scopus citations

Calcium signaling induces acquisition of dendritic cell characteristics in chronic myelogenous leukemia myeloid progenitor cells

Engels, F. H. C., Koski, G. K., Bedrosian, I., Xu, S., Luger, S., Nowell, P. C., Cohen, P. A. & Czerniecki, B. J., Aug 31 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 18, p. 10332-10337 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Formation of nitric oxide-derived oxidants by myeloperoxidase in monocytes pathways for monocyte-mediated protein nitration and lipid peroxidation in vivo

Hazen, S. L., Zhang, R., Shen, Z., Wu, W., Podrez, E. A., MacPherson, J. C., Schmitt, D., Mitra, S. N., Mukhopadhyay, C., Chen, Y., Cohen, P. A., Hoff, H. F. & Abu-Soud, H. M., Nov 12 1999, In : Circulation Research. 85, 10, p. 950-958 9 p.

Research output: Contribution to journalArticle

188 Scopus citations
2000

Bacterial lipopolysaccharide, TNF-α, and calcium ionophore under serum-free conditions promote rapid dendritic cell-like differentiation in CD14+ monocytes through distinct pathways that activate NF-κB

Lyakh, L. A., Koski, G. K., Telford, W., Gress, R. E., Cohen, P. A. & Rice, N. R., Oct 1 2000, In : Journal of Immunology. 165, 7, p. 3647-3655 9 p.

Research output: Contribution to journalArticle

107 Scopus citations

Calcium ionophore activation of chronic myelogenous leukemia progenitor cells into dendritic cells is mediated by calcineurin phosphatase

Engels, F. H. C., Kreisel, D., Faries, M. B., Bedrosian, I., Koski, G. K., Cohen, P. A. & Czerniecki, B. J., Oct 2000, In : Leukemia Research. 24, 10, p. 795-804 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection

Cohen, P. A., Peng, L., Plautz, G. E., Kim, J. A., Weng, D. E. & Shu, S., 2000, In : Critical Reviews in Immunology. 20, 1, p. 17-56 40 p.

Research output: Contribution to journalArticle

95 Scopus citations

Cross-presentation of tumor antigens to effector T cells is sufficient to mediate effective immunotherapy of established intracranial tumors

Plautz, G. E., Mukai, S., Cohen, P. A. & Shu, S., Oct 1 2000, In : Journal of Immunology. 165, 7, p. 3656-3662 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Erratum: Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species (Journal of Clinical Investigation (2000) 105 (1095-1108))

Podrez, E. A., Febbraio, M., Sheibani, N., Schmitt, D., Silverstein, R. L., Hajjar, D. P., Cohen, P. A., Frazier, W. A., Hoff, H. F. & Hazen, S. L., 2000, In : Journal of Clinical Investigation. 105, 10, p. 1483 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Granulocyte-macrophage colony-stimulating factor, interleukin-2, and interleukin-12 synergize with calcium ionophore to enhance dendritic cell function

Bedrosian, I., Roros, J. G., Xu, S., Nguyen, H. Q., Engels, F., Faries, M. B., Czerniecki, B. J., Koski, G. K. & Cohen, P. A., 2000, In : Journal of Immunotherapy. 23, 3, p. 2675 1 p.

Research output: Contribution to journalArticle

Granulocyte-macrophage colony-stimulating factor, interleukin-2, and interleukin-12 synergize with calcium ionophore to enhance dendritic cell function

Bedrosian, I., Roros, J. G., Xu, S., Nguyen, H. Q., Engels, F., Faries, M. B., Koski, G. K., Cohen, P. A. & Czerniecki, B. J., May 2000, In : Journal of Immunotherapy. 23, 3, p. 311-320 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Helper-independent, L-selectin(low) CD8+ T cells with broad anti-tumor efficacy are naturally sensitized during tumor progression

Peng, L., Kjaergaard, J., Plautz, G. E., Weng, D. E., Shu, S. & Cohen, P. A., Nov 15 2000, In : Journal of Immunology. 165, 10, p. 5738-5749 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species

Podrez, E. A., Febbraio, M., Sheibani, N., Schmitt, D., Silverstein, R. L., Hajjar, D. P., Cohen, P. A., Frazier, W. A., Hoff, H. F. & Hazen, S. L., Apr 2000, In : Journal of Clinical Investigation. 105, 8, p. 1095-1108 14 p.

Research output: Contribution to journalArticle

325 Scopus citations

T cell adoptive immunotherapy of newly diagnosed gliomas

Plautz, G. E., Miller, D. W., Barnett, G. H., Stevens, G. H. J., Maffett, S., Kim, J., Cohen, P. A. & Shu, S., Jun 2000, In : Clinical Cancer Research. 6, 6, p. 2209-2218 10 p.

Research output: Contribution to journalArticle

135 Scopus citations

T cell-mediated tumor rejection displays diverse dependence upon perforin and IFN-γ mechanisms that cannot be predicted from in vitro T cell characteristics

Peng, L., Krauss, J. C., Plautz, G. E., Mukai, S., Shu, S. & Cohen, P. A., Dec 15 2000, In : Journal of Immunology. 165, 12, p. 7116-7124 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
2001

Augmentation versus inhibition: Effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor

Kjaergaard, J., Peng, L., Cohen, P. A., Drazba, J. A., Weinberg, A. D. & Shu, S., Dec 1 2001, In : Journal of Immunology. 167, 11, p. 6669-6677 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Calcium signaling inhibits interleukin-12 production and activates CD83 + dendritic cells that induce Th2 cell development

Faries, M. B., Bedrosian, I., Xu, S., Koski, G., Roros, J. G., Moise, M. A., Nguyen, H. Q., Engels, F. H. C., Cohen, P. A. & Czerniecki, B. J., Oct 15 2001, In : Blood. 98, 8, p. 2489-2497 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

CD14+ monocytes as dendritic cell precursors: Diverse maturation-inducing pathways lead to common activation of NF-κB/RelB

Koski, G. K., Lyakh, L. A., Cohen, P. A. & Rice, N. R., 2001, In : Critical Reviews in Immunology. 21, 1-3, p. 179-189 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Diverse functional activity of CD83+ monocyte-derived dendritic cells and the implications for cancer vaccines

Czerniecki, B. J., Cohen, P. A., Faries, M., Xu, S., Roros, J. G. & Bedrosian, I., 2001, In : Critical Reviews in Immunology. 21, 1-3, p. 157-178 22 p.

Research output: Contribution to journalArticle

38 Scopus citations

Mechanism of tumor eradication by transfer of sensitized T cells

Shu, S. & Cohen, P. A., 2001, In : European Journal of Cancer. 37, SUPPL. 1

Research output: Contribution to journalArticle

T-cell adoptive therapy of tumors: Mechanisms of improved therapeutic performance

Peng, L., Cohen, P. A., Kjaergaard, J., Plautz, G. E., Finke, J. H., Koski, G. K., Czerniecki, B. J. & Shu, S., 2001, In : Critical Reviews in Immunology. 21, 1-3, p. 215-248 34 p.

Research output: Contribution to journalArticle

47 Scopus citations

Tumor-dendritic cell fusion technology and immunotherapy strategies

Shu, S. & Cohen, P. A., 2001, In : Journal of Immunotherapy. 24, 2, p. 99-100 2 p.

Research output: Contribution to journalArticle

20 Scopus citations
2002

Adenovirus type 5 vectors induce dendritic cell differentiation in human CD14 + monocytes cultured under serum-free conditions

Lyakh, L. A., Koski, G. K., Young, H. A., Spence, S. E., Cohen, P. A. & Rice, N. R., Jan 15 2002, In : Blood. 99, 2, p. 600-608 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Immunogenicity and therapeutic efficacy of dendritic-tumor hybrid cells generated by electrofusion

Hayashi, T., Tanaka, H., Tanaka, J., Wang, R., Averbook, B. J., Cohen, P. A. & Shu, S., 2002, In : Clinical Immunology. 104, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

Tumor-induced L-selectinhigh suppressor T cells mediate potent effector T cell blockade and cause failure of otherwise curative adoptive immunotherapy

Peng, L., Kjaergäard, J., Plautz, G. E., Awad, M., Drazba, J. A., Shu, S. & Cohen, P. A., Nov 1 2002, In : Journal of Immunology. 169, 9, p. 4811-4821 11 p.

Research output: Contribution to journalArticle

39 Scopus citations
2003

Considerations on clinical use of T cell immunotherapy for cancer

Plautz, G. E., Cohen, P. A. & Shu, S., 2003, In : Archivum Immunologiae et Therapiae Experimentalis. 51, 4, p. 245-257 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Intranodal administration of peptide-pulsed mature dendritic cell vaccines results in superior CD8+ T-cell function in melanoma patients

Bedrosian, I., Mick, R., Xu, S., Nisenbaum, H., Faries, M., Zhang, P., Cohen, P. A., Koski, G. & Czerniecki, B. J., Oct 15 2003, In : Journal of Clinical Oncology. 21, 20, p. 3826-3835 10 p.

Research output: Contribution to journalArticle

144 Scopus citations

Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism

Xu, S., Koski, G. K., Faries, M., Bedrosian, I., Mick, R., Maeurer, M., Cheever, M. A., Cohen, P. A. & Czerniecki, B. J., Sep 1 2003, In : Journal of Immunology. 171, 5, p. 2251-2261 11 p.

Research output: Contribution to journalArticle

118 Scopus citations

Therapeutic efficacy of adoptive immunotherapy is predicated on in vivo antigen-specific proliferation of donor T cells

Kjaergaard, J., Peng, L., Cohen, P. A. & Shu, S., Jul 1 2003, In : Clinical Immunology. 108, 1, p. 8-20 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2004

Adoptive immunotherapy of cancer with polyclonal, 108-fold hyperexpanded, CD4+ and CD8+T cells

Wang, L. X., Huang, W. X., Graor, H., Cohen, P. A., Kim, J. A., Shu, S. & Plautz, G. E., Nov 26 2004, In : Journal of Translational Medicine. 2

Research output: Contribution to journalArticle

23 Scopus citations

Cutting Edge: Innate Immune System Discriminates between RNA Containing Bacterial versus Eukaryotic Structural Features That Prime for High-Level, IL-12 Secretion by Dendritic Cells

Koski, G. K., Karikó, K., Xu, S., Weissman, D., Cohen, P. A. & Czerniecki, B. J., Apr 1 2004, In : Journal of Immunology. 172, 7, p. 3989-3993 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Memory T Cells Originate from Adoptively Transferred Effectors and Reconstituting Host Cells after Sequential Lymphodepletion and Adoptive Immunotherapy

Wang, L. X., Kjaergaard, J., Cohen, P. A., Shu, S. & Plautz, G. E., Mar 15 2004, In : Journal of Immunology. 172, 6, p. 3462-3468 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Therapeutic vaccine generated by electrofusion of dendritic cells and tumour cells.

Kuriyama, H., Shimizu, K., Lee, W., Kjaergaard, J., Parkhurst, M. R., Cohen, P. A. & Shu, S., 2004, In : Developments in Biologicals. 116

Research output: Contribution to journalArticle

15 Scopus citations
2006

Mechanism of third signals provided by IL-12 and OX-40R ligation in eliciting therapeutic immunity following dendritic-tumor fusion vaccination

Kuriyama, H., Watanabe, S., Kjaergaard, J., Tamai, H., Zheng, R., Weinberg, A. D., Hu, H. M., Cohen, P. A., Plautz, G. E. & Shu, S., 2006, In : Cellular Immunology. 243, 1, p. 30-40 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
2007

Immunogenicity of dendritic-tumor fusion hybrids and their utility in cancer immunotherapy

Shu, S., Zheng, R., Lee, W. T. & Cohen, P. A., 2007, In : Critical Reviews in Immunology. 27, 5, p. 463-483 21 p.

Research output: Contribution to journalArticle

24 Scopus citations

Improving immunotherapy by conditionally enhancing MHC class I presentation of tumor antigen-derived peptide epitopes

Storkus, W. J., Herrem, C., Kawabe, M., Cohen, P. A., Bukowski, R. M., Finke, J. H. & Wesa, A. K., 2007, In : Critical Reviews in Immunology. 27, 5, p. 485-493 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy.

Zheng, R., Kjaergaard, J., Lee, W. T., Cohen, P. A. & Shu, S., 2007, In : Cancer Treatment and Research. 135, p. 223-237 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion

Czerniecki, B. J., Koski, G. K., Koldovsky, U., Xu, S., Cohen, P. A., Mick, R., Nisenbaum, H., Pasha, T., Xu, M., Fox, K. R., Weinstein, S., Orel, S. G., Vonderheide, R., Coukos, G., DeMichele, A., Araujo, L., Spitz, F. R., Rosen, M., Levine, B. L., June, C. & 1 others, Zhang, P. J., Feb 15 2007, In : Cancer Research. 67, 4, p. 1842-1852 11 p.

Research output: Contribution to journalArticle

190 Scopus citations
2008

Effective treatment of spontaneous metastases derived from a poorly immunogenic murine mammary carcinoma by combined dendritic-tumor hybrid vaccination and adoptive transfer of sensitized T cells

Tamai, H., Watanabe, S., Zheng, R., Deguchi, K., Cohen, P. A., Koski, G. K. & Shu, S., Apr 2008, In : Clinical Immunology. 127, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Immunotherapy of established murine squamous cell carcinoma using fused dendritic-tumor cell hybrids

Lee, W. T., Tamai, H., Cohen, P. A., Teker, A. M. & Shu, S., Jun 2008, In : Archives of Otolaryngology - Head and Neck Surgery. 134, 6, p. 608-613 6 p.

Research output: Contribution to journalArticle

5 Scopus citations