• 10302 Citations
  • 43 Scopus h-Index
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Fingerprint Dive into the research topics where Pamela J McLean is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Synucleins Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
alpha-Synuclein Medicine & Life Sciences
Lewy Body Disease Medicine & Life Sciences
Proteins Medicine & Life Sciences
Lewy Bodies Medicine & Life Sciences
Neurons Medicine & Life Sciences
Molecular Chaperones Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2018

Adenosine Triphosphate
Parkinson Disease
Brain Injuries
Traumatic Brain Injury
Parkinson Disease
Lewy Bodies
Lewy Body Disease
Molecular Chaperones

Research Output 1995 2019

  • 10302 Citations
  • 43 Scopus h-Index
  • 90 Article
  • 2 Chapter
  • 1 Review article
2 Citations (Scopus)

CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage

Sun, J., Carlson-Stevermer, J., Das, U., Shen, M., Delenclos, M., Snead, A. M., Koo, S. Y., Wang, L., Qiao, D., Loi, J., Petersen, A. J., Stockton, M., Bhattacharyya, A., Jones, M. V., Zhao, X., McLean, P. J., Sproul, A. A., Saha, K. & Roy, S., Dec 1 2019, In : Nature Communications. 10, 1, 53.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Amyloid beta-Protein Precursor
Protein C
6 Citations (Scopus)

14-3-3 proteins reduce cell-to-cell transfer and propagation of pathogenic α-synuclein

Wang, B., Underwood, R., Kamath, A., Britain, C., McFerrin, M. B., McLean, P. J., Volpicelli-Daley, L. A., Whitaker, R. H., Placzek, W. J., Becker, K., Ma, J. & Yacoubian, T. A., Sep 19 2018, In : Journal of Neuroscience. 38, 38, p. 8211-8232 22 p.

Research output: Contribution to journalArticle

14-3-3 Proteins
Transfer (Psychology)
Lab-On-A-Chip Devices
2 Citations (Scopus)

Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice

Cai, W., Feng, D., Schwarzschild, M. A., McLean, P. J. & Chen, X., Mar 1 2018, In : EBioMedicine. 29, p. 13-22 10 p.

Research output: Contribution to journalArticle

384 Citations (Scopus)

Diagnosis and management of dementia with Lewy bodies

McKeith, I. G., Boeve, B. F., Dickson, D. W., Halliday, G., Taylor, J. P., Weintraub, D., Aarsland, D., Galvin, J., Attems, J., Ballard, C. G., Bayston, A., Beach, T. G., Blanc, F., Bohnen, N., Bonanni, L., Bras, J., Brundin, P., Burn, D., Chen-Plotkin, A., Duda, J. E. & 43 othersEl-Agnaf, O., Feldman, H., Ferman, T. J., Ffytche, D., Fujishiro, H., Galasko, D., Goldman, J. G., Gomperts, S. N., Graff Radford, N. R., Honig, L. S., Iranzo, A., Kantarci, K. M., Kaufer, D., Kukull, W., Lee, V. M. Y., Leverenz, J. B., Lewis, S., Lippa, C., Lunde, A., Masellis, M., Masliah, E., McLean, P. J., Mollenhauer, B., Montine, T. J., Moreno, E., Mori, E., Murray, M. E., O'Brien, J. T., Orimo, S., Postuma, R. B., Ramaswamy, S., Ross, O. A., Salmon, D. P., Singleton, A., Taylor, A., Thomas, A., Tiraboschi, P., Toledo, J. B., Trojanowski, J. Q., Tsuang, D., Walker, Z., Yamada, M. & Kosaka, K., Jul 4 2017, In : Neurology. 89, 1, p. 88-100 13 p.

Research output: Contribution to journalReview article

Lewy Body Disease
REM Sleep Behavior Disorder
Lewy Bodies
Myocardial Perfusion Imaging
11 Citations (Scopus)

Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates

Jiang, P., Gan, M., Yen, S. H., McLean, P. J. & Dickson, D. W., Dec 1 2017, In : Scientific Reports. 7, 1, 7690.

Research output: Contribution to journalArticle