• 11554 Citations
  • 46 Scopus h-Index

Research output per year

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Fingerprint Dive into the research topics where Pamela J McLean is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Research Output

  • 11554 Citations
  • 46 Scopus h-Index
  • 85 Article
  • 10 Review article
  • 2 Chapter
  • 1 Letter

Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway

Park, J. H., Burgess, J. D., Faroqi, A. H., Demeo, N. N., Fiesel, F. C., Springer, W., Delenclos, M. & McLean, P. J., Jan 13 2020, In : Molecular neurodegeneration. 15, 1, 5.

Research output: Contribution to journalArticle

Open Access
  • 1 Scopus citations

    APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

    Zhao, N., Attrebi, O. N., Ren, Y., Qiao, W., Sonustun, B., Martens, Y. A., Meneses, A. D., Li, F., Shue, F., Zheng, J., van Ingelgom, A. J., Davis, M. D., Kurti, A., Knight, J. A., Linares, C., Chen, Y., Delenclos, M., Liu, C. C., Fryer, J. D., Asmann, Y. W. & 4 others, McLean, P. J., Dickson, D. W., Ross, O. A. & Bu, G., Feb 5 2020, In : Science translational medicine. 12, 529, eaay1809.

    Research output: Contribution to journalArticle

  • 7 Scopus citations

    Cellular models of alpha-synuclein toxicity and aggregation

    Delenclos, M., Burgess, J. D., Lamprokostopoulou, A., Outeiro, T. F., Vekrellis, K. & McLean, P. J., Jan 1 2019, In : Journal of neurochemistry. 150, 5, p. 566-576 11 p.

    Research output: Contribution to journalReview article

    Open Access
  • 6 Scopus citations

    CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage

    Sun, J., Carlson-Stevermer, J., Das, U., Shen, M., Delenclos, M., Snead, A. M., Koo, S. Y., Wang, L., Qiao, D., Loi, J., Petersen, A. J., Stockton, M., Bhattacharyya, A., Jones, M. V., Zhao, X., McLean, P. J., Sproul, A. A., Saha, K. & Roy, S., Dec 1 2019, In : Nature Communications. 10, 1, 53.

    Research output: Contribution to journalArticle

  • 8 Scopus citations

    Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease

    Grozdanov, V., Bousset, L., Hoffmeister, M., Bliederhaeuser, C., Meier, C., Madiona, K., Pieri, L., Kiechle, M., McLean, P. J., Kassubek, J., Behrends, C., Ludolph, A. C., Weishaupt, J. H., Melki, R. & Danzer, K. M., Oct 1 2019, In : Annals of neurology. 86, 4, p. 593-606 14 p.

    Research output: Contribution to journalArticle

    Open Access
  • 5 Scopus citations