• 27577 Citations
  • 95 Scopus h-Index
1973 …2020

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Article
1997

Characterization of apical and basolateral plasma membrane domains derived from cultured rat cholangiocytes

Tietz, P., Levine, S., Holman, R., Fretham, C. & Larusso, N. F., Dec 15 1997, In : Analytical Biochemistry. 254, 2, p. 192-199 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
52 Scopus citations

Gene expression and polarized distribution of membrane acid/base carriers in a differentiated rat cholangiocyte cell line (NRC-1)

Spirli, C., Granato, A., Zsembery, A., Okolicsanyi, L., LaRusso, N. F. & Strazzabosco, M., Dec 1 1997, In : Italian Journal of Gastroenterology and Hepatology. 29, 1, 1 p.

Research output: Contribution to journalArticle

Kinetic and molecular identification of sodium-dependent glucose transporter in normal rat cholangiocytes

Lazaridis, K. N., Pham, L., Vroman, B., De Groen, P. C. & LaRusso, N. F., May 1 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 5 35-5, p. G1168-G1174

Research output: Contribution to journalArticle

54 Scopus citations

Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation

Alpini, G., Ulrich, C., Roberts, S., Phillips, J. O., Ueno, Y., Podila, P. V., Colegio, O., LeSage, G. D., Miller, L. J. & LaRusso, N. F., Feb 1 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 2 35-2, p. G289-G297

Research output: Contribution to journalArticle

116 Scopus citations

Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter

Lazaridis, K. N., Pham, L., Tietz, P., Marinelli, R. A., DeGroen, P. C., Levine, S., Dawson, P. A. & LaRusso, N. F., Dec 1 1997, In : Journal of Clinical Investigation. 100, 11, p. 2714-2721 8 p.

Research output: Contribution to journalArticle

Open Access
204 Scopus citations

Regulation of biliary secretion through apical purinergic receptors in cultured rat cholangiocytes

Schlenker, T., Romac, J. M. J., Sharara, A. I., Roman, R. M., Kim, S. J., Larusso, N., Liddle, R. A. & Gregory Fitz, J., Dec 9 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 273, 5 36-5, p. G1108-G1117

Research output: Contribution to journalArticle

71 Scopus citations

Sclerosing cholangitis

Marotta, P. J., LaRusso, N. F. & Wiesner, R. H., Dec 1997, In : Bailliere's Clinical Gastroenterology. 11, 4, p. 781-800 20 p.

Research output: Contribution to journalArticle

9 Scopus citations
161 Scopus citations

The pathobiology of biliary epithelia

Roberts, S. K., Ludwig, J. & LaRusso, N. F., Jan 1 1997, In : Gastroenterology. 112, 1, p. 269-279 11 p.

Research output: Contribution to journalArticle

108 Scopus citations
1996

Comparison of surgical treatment of ulcerative colitis associated with primary sclerosing cholangitis: Heal pouch-anal anastomosis versus brooke ileostomy

Kartheuser, A. H., Dozois, R. R., Larusso, N. F., Wiesner, R. H., Ilstrup, D. M. & Schleck, C. D., Jan 1 1996, In : Mayo Clinic proceedings. 71, 8, p. 748-756 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Development and characterization of a rodent model of immune-mediated cholangitis

Ueno, Y., Phillips, J. O., Ludwig, J., Lichtman, S. N. & LaRusso, N. F., Jan 9 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 1, p. 216-220 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cells

Vroman, B. & LaRusso, N. F., Jan 1 1996, In : Laboratory Investigation. 74, 1, p. 303-313 11 p.

Research output: Contribution to journalArticle

108 Scopus citations

Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver

Alpini, G., Roberts, S., Kuntz, S. M., Ueno, Y., Gubba, S., Podila, P. V., LeSage, G. & LaRusso, N. F., Jan 1 1996, In : Gastroenterology. 110, 5, p. 1636-1643 8 p.

Research output: Contribution to journalArticle

183 Scopus citations

Morphology, physiology, and biochemistry of biliary epithelia

Larusso, N. F., Jan 1 1996, In : Toxicologic Pathology. 24, 1, p. 84-89 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Passing the torch: A look back at our editorship

LaRusso, N. F., Phillips, S. F., Bloomer, J. R., Boland, C. R., Chang, E. B., DiMagno, E. P., Giannella, R. A., Gores, G. J., Malagelada, J. R., Miller, L. J., Rakela, J., Szurszewski, J. H., Binder, H. J., Clain, J. E., LaMont, J. T. & Link, A. M., Jan 1 1996, In : Gastroenterology. 110, 5, p. 1336-1338 3 p.

Research output: Contribution to journalArticle

Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with associated primary sclerosing cholangitis

Penna, C., Dozois, R., Tremaine, W., Sandborn, W., LaRusso, N., Schleck, C. & Ilstrup, D., Jan 1 1996, In : Gut. 38, 2, p. 234-239 6 p.

Research output: Contribution to journalArticle

Open Access
405 Scopus citations

Rat hepatocytes transport water mainly via a non-channel-mediated pathway

Yano, M., Marinelli, R. A., Roberts, S. K., Balan, V., Pham, L., Tarara, J. E., De Groen, P. C. & LaRusso, N. F., Mar 22 1996, In : Journal of Biological Chemistry. 271, 12, p. 6702-6707 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Solute and water transport pathways in cholangiocytes

Marinelli, R. A. & LaRusso, N. F., Jan 1 1996, In : Seminars in Liver Disease. 16, 2, p. 221-229 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Somatostatin receptor imaging in cholangiocarcinoma [1]

Jamar, F., Pauwels, S., Horsmans, Y., Deprez, P., Tan, C. K., Larusso, N. F. & Gores, G. J., Jan 1 1996, In : Gastroenterology. 110, 5, p. 1675-1676 2 p.

Research output: Contribution to journalArticle

Ursodeoxycholic acid and methotrexate for primary sclerosing cholangitis: A pilot study

Lindor, K. D., Jorgensen, R. A., Anderson, M. L., Gores, G. J., Hofmann, A. F. & LaRusso, N. F., Mar 1 1996, In : American Journal of Gastroenterology. 91, 3, p. 511-515 5 p.

Research output: Contribution to journalArticle

80 Scopus citations
1995

Dynamic measurements of the acute and chronic effects of lysosomotropic agents on hepatocyte lysosomal pH using flow cytometry

Myers, B. M., Tietz, P. S., Tarara, J. E. & Larusso, N. F., Nov 1995, In : Hepatology. 22, 5, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Human cholangiocarcinomas express somatostatin receptors and respond to somatostatin with growth inhibition

Chee Kiat Tan, K. T., Podila, P. V., Taylor, J. E., Nagorney, D. M., Wiseman, G. A., Gores, G. J. & Larusso, N. F., Jun 1995, In : Gastroenterology. 108, 6, p. 1908-1916 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Isolation and Characterization of Rat Cholangiocyte Vesicles Enriched in Apical or Basolateral Plasma Membrane Domains

Tietz, P. S., Holman, R. T., Miller, L. J. & LaRusso, N. F., Nov 1995, In : Biochemistry. 34, 47, p. 15436-15443 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Isolation of the microtubule-vesicle motor kinesin from rat liver: Selective inhibition by cholestatic bile acids

Marks, D. L., LaRusso, N. F. & McNiven, M. A., Mar 1995, In : Gastroenterology. 108, 3, p. 824-833 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Quantitative importance of biliary excretion to the turnover of hepatic lysosomal enzymes

Nakano, A., Marks, D. L., Tietz, P. S., De Groen, P. C. & Larusso, N. F., Jul 1995, In : Hepatology. 22, 1, p. 262-266 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Serum lipid and fat-soluble vitamin levels in primary sclerosing cholangitis

Jorgensen, R. A., Lindor, K. D., Sartin, J. S., LaRusso, N. F. & Wiesner, R. H., Apr 1995, In : Journal of clinical gastroenterology. 20, 3, p. 215-219 5 p.

Research output: Contribution to journalArticle

61 Scopus citations

Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes

Tietz, P. S., Alpini, G., Pham, L. D. & LaRusso, N. F., Jan 1 1995, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 269, 1 32-1, p. G110-G118

Research output: Contribution to journalArticle

93 Scopus citations
1994

Cholangiocytes express the aquaporin CHIP and transport water via a channel-mediated mechanism

Roberts, S. K., Yano, M., Ueno, Y., Pham, L., Alpini, G., Agre, P. & Larusso, N. F., Dec 20 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 26, p. 13009-13013 5 p.

Research output: Contribution to journalArticle

108 Scopus citations

Primary sclerosing cholangitis

Ueno, Y. & LaRusso, N. F., Aug 1 1994, In : Journal of gastroenterology. 29, 4, p. 531-543 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Purification and partial characterization of a heat-resistant, cytosolic neuropeptidase from rat liver

Janas, R. M., Marks, D. L. & LaRusso, N. F., Jan 31 1994, In : Biochemical and Biophysical Research Communications. 198, 2, p. 574-581 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Recent advances in the isolation of liver cells

Alpini, G., Phillips, J. O., Vroman, B. & Larusso, N. F., Aug 1994, In : Hepatology. 20, 2, p. 494-514 21 p.

Research output: Contribution to journalArticle

143 Scopus citations

Upregulation of secretin receptor gene expression in rat cholangiocytes after bile duct ligation

Alpini, G., Ulrich, C. D., Phillips, J. O., Pham, L. D., Miller, L. J. & LaRusso, N. F., Jan 1 1994, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 266, 5 29-5, p. G922-G928

Research output: Contribution to journalArticle

122 Scopus citations
1993

Alterations in hepatocyte lysosomes in experimental hepatic copper overload in rats

Myers, B. M., Prendergast, F. G., Holman, R., Kuntz, S. M. & Larusso, N. F., Dec 1993, In : Gastroenterology. 105, 6, p. 1814-1823 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Complications and risk factors after heal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis

Kartheuser, A. H., Dozois, R. R., Wiesner, R. H., LaRusso, N. F., Ilstrup, D. M. & Schleck, C. D., Apr 1993, In : Annals of surgery. 217, 4, p. 314-320 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

COMPLICATIONS ET FACTEURS DE RISQUE DE L'ANASTOMOSE ILEO-ANALE AVEC RESERVOIR POUR RECTOCOLIE ULCERO-HEMORRAGIQUE ASSOCIEE A UNE CHOLANGITE SCLEROSANTE PRIMITIVE

Translated title of the contribution: Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitisKartheuser, A. H., Dozois, R. R., Wiesner, R. H., La Russo, N. F., Ilstrup, D. M. & Schleck, C. D., Dec 1 1993, In : Annales de Chirurgie. 47, 10, p. 1000-1008 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Diagnostic Role of Serum CA 19-9 for Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis

NICHOLS, J. CHRISTOPHER., GORES, GREGORY. J., LARUSSO, NICHOLAS. F., WIESNER, RUSSELL. H., NAGORNEY, DAVID. M. & RITTS, ROY. E., Jan 1 1993, In : Mayo Clinic proceedings. 68, 9, p. 874-879 6 p.

Research output: Contribution to journalArticle

186 Scopus citations
Open Access
65 Scopus citations

Ulcerative colitis disease activity following treatment of associated primary sclerosing cholangitis with cyclosporin

Sandborn, W. J., Wiesner, R. H., Tremaine, W. J. & Larusso, N. F., Feb 1993, In : Gut. 34, 2, p. 242-246 5 p.

Research output: Contribution to journalArticle

Open Access
55 Scopus citations
1992

An aluminum silicate binding assay for quantitationof degradation of cholecystokinin octapeptide and other short peptides

Janas, R. M., Marks, D. L. & LaRusso, N. F., Oct 1992, In : Analytical Biochemistry. 206, 1, p. 6-11 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Biological characteristics of primary cultures of human gallbladder epithelial cells

Hoerl, B. J., Vroman, B. T., Kasperbauer, J. L., LaRusso, N. F. & Scott, R. E., Jan 1 1992, In : Laboratory Investigation. 66, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Primary sclerosing cholangitis: Refinement and validation of survival models

Dickson, E. R., Murtaugh, P. A., Wiesner, R. H., Grambsch, P. M., Fleming, T. R., Ludwig, J., LaRusso, N. F., Malinchoc, M., Chapman, R. W., Kaplan, M. M., Maddrey, W. C., Williams, R., Farrant, M. & Langworthy, A., Dec 1992, In : Gastroenterology. 103, 6, p. 1893-1901 9 p.

Research output: Contribution to journalArticle

224 Scopus citations

Secretin stimulates exocytosis in isolated bile duct epithelial cells by a cyclic AMP-mediated mechanism

Kato, A., Gores, G. J. & LaRusso, N. F., Jan 1 1992, In : Journal of Biological Chemistry. 267, 22, p. 15523-15529 7 p.

Research output: Contribution to journalArticle

127 Scopus citations

Selection and timing of liver transplantation in primary biliary cirrhosis and primary sclerosing cholangitis

Wiesner, R. H., Porayko, M. K., Dickson, E. R., Gores, G. J., Larusso, N. F., Hay, J. E., Wahlstrom, H. E. & Krom, R. A. F., Nov 1992, In : Hepatology. 16, 5, p. 1290-1299 10 p.

Research output: Contribution to journalArticle

134 Scopus citations
1991

Alterations in the structure, physicochemical properties, and pH of hepatocyte lysosomes in experimental iron overload

Myers, B. M., Prendergast, F. G., Holman, R., Kuntz, S. M. & LaRusso, N. F., Jan 1 1991, In : Journal of Clinical Investigation. 88, 4, p. 1207-1215 9 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations

Cholangiocarcinoma complicating primary sclerosing cholangitis

Rosen, C. B., Nagorney, D. M., Wiesner, R. H., Coffey, R. J. & Larusso, N. F., Jan 1991, In : Annals of surgery. 213, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

304 Scopus citations

Hepatic processing of recombinant human renin: Mechanisms of uptake and degradation

Marks, D. L., Kost, L. J., Kuntz, S. M., Romero, J. C. & LaRusso, N. F., Jan 1 1991, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 261, 2 24-2, p. G349-G358

Research output: Contribution to journalArticle

14 Scopus citations

Neutrophil cytoplasmic antibodies: A link between primary sclerosing cholangitis and ulcerative colitis

Duerr, R. H., Targan, S. R., Landers, C. J., Larusso, N. F., Lindsay, K. L., Wiesner, R. H. & Shanahan, F., May 1991, In : Gastroenterology. 100, 5 PART 1, p. 1385-1391 7 p.

Research output: Contribution to journalArticle

280 Scopus citations

Primary sclerosing cholangitis: A progressive disease?

Porayko, M. K., LaRusso, N. F. & Wiesner, R. H., Feb 1991, In : Seminars in Liver Disease. 11, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

39 Scopus citations