• 7437 Citations
  • 43 Scopus h-Index
20022021
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Projects 2007 2021

Health
Sirolimus
Dehydration
Chronic Disease
Anesthesia
Growth Differentiation Factors
Plasminogen Activator Inhibitor 2
Proteins
International Classification of Diseases
Life Style

Cellular Senescence and Aging

Kirkland, J. L., Lebrasseur, N., Deursen, J., Campisi, J., Mooney, S. D. & LeBrasseur, N. K.

National Institutes of Health

5/1/124/30/17

Project: Research project

Cell Aging
Phenotype
Advisory Committees
Research
Fats
Protein Biosynthesis
Androgens
Skeletal Muscle
Muscles
Testosterone

Research Output 2002 2019

  • 7437 Citations
  • 43 Scopus h-Index
  • 88 Article
  • 3 Review article
  • 1 Chapter
  • 1 Editorial
2 Citations (Scopus)

Frailty and clinical outcomes in chronic obstructive pulmonary disease

NETT Research Group, Feb 1 2019, In : Annals of the American Thoracic Society. 16, 2, p. 217-224 8 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Confidence Intervals
Emphysema
Forced Expiratory Volume
Phenotype
5 Citations (Scopus)

Length-independent telomere damage drives post-mitotic cardiomyocyte senescence

Anderson, R., Lagnado, A., Maggiorani, D., Walaszczyk, A., Dookun, E., Chapman, J., Birch, J., Salmonowicz, H., Ogrodnik, M., Jurk, D., Proctor, C., Correia-Melo, C., Victorelli, S., Fielder, E., Berlinguer-Palmini, R., Owens, A., Greaves, L. C., Kolsky, K. L., Parini, A., Douin-Echinard, V. & 14 othersLeBrasseur, N. K., Arthur, H. M., Tual-Chalot, S., Schafer, M. J., Roos, C. M., Miller, J. D., Robertson, N., Mann, J., Adams, P. D., Tchkonia, T., Kirkland, J. L., Mialet-Perez, J., Richardson, G. D. & Passos, J. F., Mar 1 2019, In : EMBO Journal. 38, 5, e100492.

Research output: Contribution to journalArticle

Open Access
Telomere
Cardiac Myocytes
Aging of materials
Tissue
Telomere Shortening
21 Citations (Scopus)

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

Justice, J. N., Nambiar, A. M., Tchkonia, T., LeBrasseur, N. K., Pascual, R., Hashmi, S. K., Prata, L., Masternak, M. M., Kritchevsky, S. B., Musi, N. & Kirkland, J. L., Jan 1 2019, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Quercetin
Labels
Cell Aging
Phenotype
3 Citations (Scopus)

Targeting senescent cells alleviates obesity-induced metabolic dysfunction

Palmer, A. K., Xu, M., Zhu, Y., Pirtskhalava, T., Weivoda, M. M., Hachfeld, C. M., Prata, L. G., van Dijk, T. H., Verkade, E., Casaclang-Verzosa, G., Johnson, K. O., Cubro, H., Doornebal, E. J., Ogrodnik, M., Jurk, D., Jensen, M. D., Chini, E. N., Miller, J. D., Matveyenko, A. V., Stout, M. B. & 13 othersSchafer, M. J., White, T. A., Hickson, L., Demaria, M., Garovic, V. D., Grande, J. P., Arriaga, E. A., Kuipers, F., von Zglinicki, T., LeBrasseur, N. K., Campisi, J., Tchkonia, T. & Kirkland, J. L., Jun 1 2019, In : Aging Cell. 18, 3, e12950.

Research output: Contribution to journalArticle

Open Access
Adipogenesis
Cell Aging
Quercetin
Type 2 Diabetes Mellitus
Obesity

The clinical impact and biological mechanisms of skeletal muscle aging

Aversa, Z., Zhang, X., Fielding, R. A., Lanza, I. R. & LeBrasseur, N. K., Oct 1 2019, In : Bone. 127, p. 26-36 11 p.

Research output: Contribution to journalArticle

Sarcopenia
Skeletal Muscle
Muscles
Muscular Atrophy
Cell Aging