Michael Barrett, PhD

Associate Consultant

  • 4315 Citations
  • 31 h-Index
19952018
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Projects 2010 2013

High Definition Clonal Analyses of Archival Pancreatic Adenocarcinoma Samples

Barrett, M.

National Institutes of Health

3/1/102/28/13

Project: Research projectExploratory/Developmental Grants

Adenocarcinoma
Neoplasms
Genome
Clonal Evolution
Genomic Instability

Research Output 1995 2018

  • 4315 Citations
  • 31 h-Index
  • 64 Article
  • 1 Chapter
  • 1 Conference contribution

Delineation of human prostate cancer evolution identifies chromothripsis as a polyclonal event and FKBP4 as a potential driver of castration resistance

Federer-Gsponer, J. R., Quintavalle, C., Müller, D. C., Dietsche, T., Perrina, V., Lorber, T., Juskevicius, D., Lenkiewicz, E., Zellweger, T., Gasser, T., Barrett, M., Rentsch, C. A., Bubendorf, L. & Ruiz, C., May 1 2018, In : Journal of Pathology. 245, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Androgen Receptors
Neoplasms
DNA Fingerprinting
1 Citations

JAK2 and PD-L1 Amplification Enhance the Dynamic Expression of PD-L1 in Triple-negative Breast Cancer

Chen, M., Pockaj, B. A., Andreozzi, M., Barrett, M., Krishna, S., Eaton, S., Niu, R. & Anderson, K. S., Jan 1 2018, (Accepted/In press) In : Clinical Breast Cancer.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Cell Death
Ligands
Interferon-gamma
Comparative Genomic Hybridization

The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

Barrett, M., Lenkiewicz, E., Malasi, S., Basu, A., Yearley, J. H., Annamalai, L., McCullough, A. E., Kosiorek, H. E., Narang, P., Wilson Sayres, M. A., Chen, M., Anderson, K. S. & Pockaj, B. A., Jul 11 2018, In : Breast Cancer Research. 20, 1, 71.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Neoplasms
Staining and Labeling
Microsatellite Instability
Aneuploidy
4 Citations

A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma

Goncalves, P. H., Heilbrun, L. K., Barrett, M., Kummar, S., Hansen, A. R., Siu, L. L., Piekarz, R. L., Sukari, A. W., Chao, J., Pilat, M. J., Smith, D. W., Casetta, L., Boerner, S. A., Chen, A., Lenkiewicz, E., Malasi, S. & LoRusso, P. M., 2017, In : Oncotarget. 8, 20, p. 32918-32929 12 p.

Research output: Contribution to journalArticle

Adenoid Cystic Carcinoma
Exome
Histone Deacetylase Inhibitors
vorinostat
Lymphopenia

A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients

Ramanathan, R. K., Weiss, G. J., Posner, R. G., Rajeshkumar, N. V., Jameson, G., Aziz, M., Hoering, A., Bolejack, V., Maitra, A., Fulk, M., Stites, E. C., Hlavacek, W. S., Gatalica, Z., Xiu, J., Hidalgo, M., Von Hoff, D. D. & Barrett, M., Dec 1 2017, In : Journal of Gastrointestinal Oncology. 8, 6, p. 925-935 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Immunohistochemistry
Neoplasms
Biopsy
irinotecan