• 4645 Citations
  • 32 Scopus h-Index
19952019
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Research Output 1995 2019

  • 4645 Citations
  • 32 Scopus h-Index
  • 67 Article
  • 1 Chapter
  • 1 Conference contribution
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Article
2019

Clonal analyses of refractory testicular germ cell tumors

Barrett, M., Lenkiewicz, E., Malasi, S., Stanton, M., Slack, J. L., Andrews, P., Pagliaro, L. & Bryce, A. H., Mar 1 2019, In : PloS one. 14, 3, e0213815.

Research output: Contribution to journalArticle

Open Access
Refractory materials
Tumors
germ cells
Cells
neoplasms

Enhanced DNA repair and genomic stability identify a novel HIV-related diffuse large B-cell lymphoma signature

Maguire, A., Chen, X., Wisner, L., Malasi, S., Ramsower, C., Kendrick, S., Barrett, M., Glinsmann-Gibson, B., McGrath, M. & Rimsza, L., Jan 1 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Genomic Instability
DNA Repair
HIV
Germinal Center
1 Citation (Scopus)

Exploring the spatiotemporal genetic heterogeneity in metastatic lung adenocarcinoma using a nuclei flow-sorting approach

Lorber, T., Andor, N., Dietsche, T., Perrina, V., Juskevicius, D., Pereira, K., Greer, S. U., Krause, A., Müller, D. C., Savic Prince, S., Lardinois, D., Barrett, M., Ruiz, C. & Bubendorf, L., Jan 1 2019, (Accepted/In press) In : Journal of Pathology.

Research output: Contribution to journalArticle

Genetic Heterogeneity
Neoplasms
Mutation
Neoplasm Metastasis
Chromosomal Instability
2018
3 Citations (Scopus)

Delineation of human prostate cancer evolution identifies chromothripsis as a polyclonal event and FKBP4 as a potential driver of castration resistance

Federer-Gsponer, J. R., Quintavalle, C., Müller, D. C., Dietsche, T., Perrina, V., Lorber, T., Juskevicius, D., Lenkiewicz, E., Zellweger, T., Gasser, T., Barrett, M., Rentsch, C. A., Bubendorf, L. & Ruiz, C., May 1 2018, In : Journal of Pathology. 245, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Androgen Receptors
Neoplasms
DNA Fingerprinting
3 Citations (Scopus)

JAK2 and PD-L1 Amplification Enhance the Dynamic Expression of PD-L1 in Triple-negative Breast Cancer

Chen, M., Pockaj, B. A., Andreozzi, M., Barrett, M., Krishna, S., Eaton, S., Niu, R. & Anderson, K. S., Jan 1 2018, (Accepted/In press) In : Clinical Breast Cancer.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Cell Death
Ligands
Interferons
Comparative Genomic Hybridization
8 Citations (Scopus)

The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

Barrett, M., Lenkiewicz, E., Malasi, S., Basu, A., Yearley, J. H., Annamalai, L., McCullough, A. E., Kosiorek, H. E., Narang, P., Wilson Sayres, M. A., Chen, M., Anderson, K. S. & Pockaj, B. A., Jul 11 2018, In : Breast Cancer Research. 20, 1, 71.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Neoplasms
Staining and Labeling
Microsatellite Instability
Aneuploidy
2017
10 Citations (Scopus)

A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma

Goncalves, P. H., Heilbrun, L. K., Barrett, M., Kummar, S., Hansen, A. R., Siu, L. L., Piekarz, R. L., Sukari, A. W., Chao, J., Pilat, M. J., Smith, D. W., Casetta, L., Boerner, S. A., Chen, A., Lenkiewicz, E., Malasi, S. & LoRusso, P. M., 2017, In : Oncotarget. 8, 20, p. 32918-32929 12 p.

Research output: Contribution to journalArticle

Adenoid Cystic Carcinoma
Exome
Histone Deacetylase Inhibitors
vorinostat
Lymphopenia

A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients

Ramanathan, R. K., Weiss, G. J., Posner, R. G., Rajeshkumar, N. V., Jameson, G., Aziz, M., Hoering, A., Bolejack, V., Maitra, A., Fulk, M., Stites, E. C., Hlavacek, W. S., Gatalica, Z., Xiu, J., Hidalgo, M., Von Hoff, D. D. & Barrett, M., Dec 1 2017, In : Journal of Gastrointestinal Oncology. 8, 6, p. 925-935 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Immunohistochemistry
Neoplasms
Biopsy
irinotecan
8 Citations (Scopus)

Clinical study of genomic drivers in pancreatic ductal adenocarcinoma

Barrett, M., Deiotte, R., Lenkiewicz, E., Malasi, S., Holley, T., Evers, L., Posner, R. G., Jones, T., Han, H., Sausen, M., Velculescu, V. E., Drebin, J., O'Dwyer, P., Jameson, G., Ramanathan, R. K. & Von Hoff, D. D., Aug 8 2017, In : British Journal of Cancer. 117, 4, p. 572-582 11 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Genome
Neoplasms
DNA Repair-Deficiency Disorders
Clinical Trials
9 Citations (Scopus)

Development and validation of a novel clinical fluorescence in situ hybridization assay to detect JAK2 and PD-L1 amplification: A fluorescence in situ hybridization assay for JAK2 and PD-L1 amplification

Chen, M., Andreozzi, M., Pockaj, B. A., Barrett, M., Ocal, I. T., McCullough, A. E., Linnaus, M. E., Chang, J. M., Yearley, J. H., Annamalai, L. & Anderson, K. S., Nov 1 2017, In : Modern Pathology. 30, 11, p. 1516-1526 11 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
Fluorescence In Situ Hybridization
Triple Negative Breast Neoplasms
Chromosomes
Molecular Targeted Therapy
16 Citations (Scopus)

Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer

Whatcott, C. J., Ng, S., Barrett, M., Hostetter, G., Von Hoff, D. D. & Han, H., Aug 1 2017, In : PLoS One. 12, 8, e0183871.

Research output: Contribution to journalArticle

pancreatic neoplasms
Fibroblasts
Stromal Cells
Pancreatic Neoplasms
fibroblasts
2016
26 Citations (Scopus)

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein

Wang, Y., Ding, X., Wang, S., Moser, C. D., Shaleh, H. M., Mohamed, E. A., Chaiteerakij, R., Allotey, L. K., Chen, G., Miyabe, K., McNulty, M. S., Ndzengue, A., Barr Fritcher, E. G., Knudson, R. A., Greipp, P. T., Clark, K. J., Torbenson, M., Kipp, B. R., Zhou, J., Barrett, M. & 4 others, Gustafson, M., Alberts, S. R., Borad, M. J. & Roberts, L. R., Sep 28 2016, In : Cancer Letters. 380, 1, p. 163-173 11 p.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 2
Cholangiocarcinoma
Heterografts
Proteins
Neoplasms
10 Citations (Scopus)

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

Borad, M. J., Egan, J. B., Condjella, R. M., Liang, W. S., Fonseca, R., Ritacca, N. R., McCullough, A. E., Barrett, M., Hunt, K. S., Champion, M. D., Patel, M. D., Young, S. W., Silva, A. C., Ho, T. H., Halfdanarson, T. R., Mc Williams, R. R., Lazaridis, K. N., Ramanathan, R. K., Baker, A., Aldrich, J. & 17 others, Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Cuyugan, L., McDonald, J., Adkins, J., Mastrian, S. D., Valdez, R., Jaroszewski, D. E., Von Hoff, D. D., Craig, D. W., Stewart, A. K., Carpten, J. D. & Bryce, A. H., 2016, In : Scientific Reports. 6, 1, 25.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
DNA Fingerprinting
Patient Preference
Pharmaceutical Preparations

Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment With Erlotinib

Bryce, A. H., Borad, M. J., Egan, J. B., Condjella, R. M., Liang, W. S., Fonseca, R., McCullough, A. E., Hunt, K. S., Ritacca, N. R., Barrett, M., Patel, M. D., Young, S. W., Silva, A. C., Ho, T. H., Halfdanarson, T. R., Stanton, M. L., Cheville, J., Swanson, S., Schneider, D. E., Mc Williams, R. R. & 16 others, Baker, A., Aldrich, J., Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Cuyugan, L., McDonald, J., Adkins, J., Mastrian, S. D., Von Hoff, D. D., Craig, D. W., Stewart, A. K. & Carpten, J. D., Nov 3 2016, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

2015
164 Citations (Scopus)

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Sausen, M., Phallen, J., Adleff, V., Jones, S., Leary, R. J., Barrett, M., Anagnostou, V., Parpart-Li, S., Murphy, D., Li, Q. K., Hruban, C. A., Scharpf, R., White, J. R., O'Dwyer, P. J., Allen, P. J., Eshleman, J. R., Thompson, C. B., Klimstra, D. S., Linehan, D. C., Maitra, A. & 6 others, Hruban, R. H., Diaz, L. A., Von Hoff, D. D., Johansen, J. S., Drebin, J. A. & Velculescu, V. E., Jul 7 2015, In : Nature Communications. 6, 7686.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Tumors
tumors
cancer
Neoplasms
4 Citations (Scopus)

Disseminated medulloblastoma in a child with germline BRCA2 6174delT mutation and without Fanconi anemia

Xu, J., Margol, A. S., Shukla, A., Ren, X., Finlay, J. L., Krieger, M. D., Gilles, F. H., Couch, F. J., Aziz, M., Fung, E. T., Asgharzadeh, S., Barrett, M. & Erdreich-Epstein, A., 2015, In : Frontiers in Oncology. 5, Aug, 191.

Research output: Contribution to journalArticle

Fanconi Anemia
Medulloblastoma
Mutation
Malignant Pleural Effusion
Germ-Line Mutation
55 Citations (Scopus)

Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer

Barrett, M., Anderson, K. S., Lenkiewicz, E., Andreozzi, M., Cunliffe, H. E., Klassen, C. L., Dueck, A., McCullough, A. E., Reddy, S. K., Ramanathan, R. K., Northfelt, D. W. & Pockaj, B. A., 2015, In : Oncotarget. 6, 28, p. 26483-26493 11 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Comparative Genomic Hybridization
Glioblastoma
Oligonucleotide Array Sequence Analysis
Disease-Free Survival
2014
70 Citations (Scopus)

Androgen receptor-positive triple negative breast cancer: A unique breast cancer subtype

McGhan, L. J., McCullough, A. E., Protheroe, C. A., Dueck, A., Lee, J. J., Nunez-Nateras, R., Castle, E. P., Gray, R. J., Wasif, N., Goetz, M. P., Hawse, J. R., Henry, T. J., Barrett, M., Cunliffe, H. E. & Pockaj, B. A., Feb 2014, In : Annals of Surgical Oncology. 21, 2, p. 361-367 7 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Androgen Receptors
Breast Neoplasms
Lymph Nodes
Carcinoma, Intraductal, Noninfiltrating
23 Citations (Scopus)

Chromosome-breakage genomic instability and chromothripsis in breast cancer

Przybytkowski, E., Lenkiewicz, E., Barrett, M., Klein, K., Nabavi, S., Greenwood, C. M. T. & Basik, M., Jul 9 2014, (Accepted/In press) In : BMC Genomics. p. 579 1 p.

Research output: Contribution to journalArticle

Chromosome Breakage
Genomic Instability
Comparative Genomic Hybridization
Breast Neoplasms
Chromosomes
15 Citations (Scopus)

Clonal evolution and therapeutic resistance in solid tumors

Barrett, M., Lenkiewicz, E., Evers, L., Holley, T., Ruiz, C., Bubendorf, L., Sekulic, A. D., Ramanathan, R. K. & Von Hoff, D. D., 2014, In : Frontiers in Pharmacology. 4 JAN, Article 2.

Research output: Contribution to journalArticle

Clonal Evolution
Population
Neoplasms
Genome
Therapeutics

Erratum: Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4 (Nature Genetics (2014) 46 (427-429))

Ramos, P., Karnezis, A. N., Craig, D. W., Sekulic, A. D., Russel, M. L., Hendricks, W. P. D., Corneveaux, J. J., Barrett, M., Shumansky, K., Yang, Y., Shah, S. P., Prentice, L. M., Marra, M. A., Kiefer, J., Zismann, V. L., McEachron, T. A., Salhia, B., Prat, J., D'Angelo, E., Clarke, B. A. & 7 others, Pressey, J. G., Farley, J. H., Anthony, S. P., Roden, R. B. S., Cunliffe, H. E., Huntsman, D. G. & Trent, J. M., 2014, In : Nature Genetics. 46, 7, p. 759 1 p.

Research output: Contribution to journalArticle

Small Cell Carcinoma
Germ-Line Mutation
Ovary
44 Citations (Scopus)

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes

Stieber, D., Golebiewska, A., Evers, L., Lenkiewicz, E., Brons, N. H. C., Nicot, N., Oudin, A., Bougnaud, S., Hertel, F., Bjerkvig, R., Vallar, L., Barrett, M. & Niclou, S. P., Feb 2014, In : Acta Neuropathologica. 127, 2, p. 203-219 17 p.

Research output: Contribution to journalArticle

Glioblastoma
Stem Cells
Clone Cells
Phenotype
Neoplasms
149 Citations (Scopus)

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

Borad, M. J., Champion, M. D., Egan, J. B., Liang, W. S., Fonseca, R., Bryce, A. H., McCullough, A. E., Barrett, M., Hunt, K., Patel, M. D., Young, S. W., Collins, J. M., Silva, A. C., Condjella, R. M., Block, M. S., Mc Williams, R. R., Lazaridis, K. N., Klee, E. W., Bible, K. C., Harris, P. & 29 others, Oliver, G. R., Bhavsar, J. D., Nair, A. A., Middha, S., Asmann, Y., Kocher, J-P., Schahl, K., Kipp, B. R., Barr Fritcher, E. G., Baker, A., Aldrich, J., Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Phillips, L., McDonald, J., Adkins, J., Mastrian, S. D., Placek, P., Watanabe, A. T., LoBello, J., Han, H., Von Hoff, D., Craig, D. W., Stewart, A. K. & Carpten, J. D., Feb 2014, In : PLoS Genetics. 10, 2, e1004135.

Research output: Contribution to journalArticle

Cholangiocarcinoma
tumor
genomics
drug
inhibitor

Mesenchymal-like pancreatic cancer cells harbor specific genomic alterations more frequently than their epithelial-like counterparts

Sinha, A., Cherba, D., Bartlam, H., Lenkiewicz, E., Evers, L., Barrett, M. & Haab, B. B., Oct 1 2014, In : Molecular Oncology. 8, 7, p. 1253-1265 13 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Genes
Phenotype
Cell Line
Comparative Genomic Hybridization
137 Citations (Scopus)

Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4

Ramos, P., Karnezis, A. N., Craig, D. W., Sekulic, A. D., Russell, M. L., Hendricks, W. P. D., Corneveaux, J. J., Barrett, M., Shumansky, K., Yang, Y., Shah, S. P., Prentice, L. M., Marra, M. A., Kiefer, J., Zismann, V. L., McEachron, T. A., Salhia, B., Prat, J., D'Angelo, E., Clarke, B. A. & 7 others, Pressey, J. G., Farley, J. H., Anthony, S. P., Roden, R. B. S., Cunliffe, H. E., Huntsman, D. G. & Trent, J. M., 2014, In : Nature Genetics. 46, 5, p. 427-429 3 p.

Research output: Contribution to journalArticle

Small Cell Carcinoma
Germ-Line Mutation
Ovary
Neoplasms
Chromatin Assembly and Disassembly
15 Citations (Scopus)

STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma

Evers, L., Perez-Mancera, P. A., Lenkiewicz, E., Tang, N., Aust, D., Knösel, T., Rümmele, P., Holley, T., Kassner, M., Aziz, M., Ramanathan, R. K., Von Hoff, D. D., Yin, H., Pilarsky, C. & Barrett, M., Jan 31 2014, In : Genome Medicine. 6, 1, 9.

Research output: Contribution to journalArticle

Adenocarcinoma
Neoplasms
Survival
Kaplan-Meier Estimate
Genome
6 Citations (Scopus)

Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements

Egan, J. B., Barrett, M., Champion, M. D., Middha, S., Lenkiewicz, E., Evers, L., Francis, P., Schmidt, J., Shi, C. X., Van Wier, S., Badar, S., Ahmann, G., Kortuem, K. M., Boczek, N. J., Fonseca, R., Craig, D. W., Carpten, J. D., Borad, M. J. & Stewart, A. K., Feb 5 2014, In : PLoS One. 9, 2, e87113.

Research output: Contribution to journalArticle

Liposarcoma
gene fusion
Genes
aneuploidy
Genome
2013
3 Citations (Scopus)

Elucidating potentially significant genomic regions involved in the initiation and progression of undifferentiated pleomorphic sarcoma

Kurywchak, P., Kiefer, J., Lenkiewicz, E., Evers, L., Holley, T., Barrett, M. & Weiss, G. J., 2013, In : Rare Tumors. 5, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

Sarcoma
Aneuploidy
Diploidy
Population
Neoplasms
2012
376 Citations (Scopus)

Clonal competition with alternating dominance in multiple myeloma

Keats, J. J., Chesi, M., Egan, J. B., Garbitt, V. M., Palmer, S. E., Braggio, E. D., Van Wier, S., Blackburn, P. R., Baker, A. S., Dispenzieri, A., Kumar, S. K., Rajkumar, S. V., Carpten, J. D., Barrett, M., Fonseca, R., Stewart, A. K. & Bergsagel, P. L., Aug 2 2012, In : Blood. 120, 5, p. 1067-1076 10 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Tumors
Clone Cells
Genes
Neoplasms
1 Citation (Scopus)

Clonal Evolution of a Case of Treatment Refractory Maxillary Sinus Carcinoma

Arora, S., Korn, R. L., Lenkiewicz, E., Cherni, I., Beach, T. G., Hostetter, G., Barrett, M. & Weiss, G. J., Sep 28 2012, In : PLoS One. 7, 9, e45614.

Research output: Contribution to journalArticle

Clonal Evolution
Maxillary Sinus
sinuses
Refractory materials
carcinoma
33 Citations (Scopus)

Deep Clonal Profiling of Formalin Fixed Paraffin Embedded Clinical Samples

Holley, T., Lenkiewicz, E., Evers, L., Tembe, W., Ruiz, C., Gsponer, J. R., Rentsch, C. A., Bubendorf, L., Stapleton, M., Amorese, D., Legendre, C., Cunliffe, H. E., McCullough, A. E., Pockaj, B. A., Craig, D., Carpten, J., Von Hoff, D., Iacobuzio-Donahue, C. & Barrett, M., Nov 30 2012, In : PLoS One. 7, 11, e50586.

Research output: Contribution to journalArticle

formalin
Paraffin
alkanes
Formaldehyde
Tissue
49 Citations (Scopus)

Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing

Liang, W. S., Craig, D. W., Carpten, J., Borad, M. J., Demeure, M. J., Weiss, G. J., Izatt, T., Sinari, S., Christoforides, A., Aldrich, J., Kurdoglu, A., Barrett, M., Phillips, L., Benson, H., Tembe, W., Braggio, E. D., Kiefer, J. A., Legendre, C., Posner, R., Hostetter, G. H. & 9 others, Baker, A., Egan, J. B., Han, H., Lake, D., Stites, E. C., Ramanathan, R. K., Fonseca, R., Stewart, A. K. & von Hoff, D., Oct 10 2012, In : PLoS One. 7, 10, e43192.

Research output: Contribution to journalArticle

adenocarcinoma
Tumors
Adenocarcinoma
Genes
Genome
7 Citations (Scopus)

Genomic analysis and selected molecular pathways in rare cancers

Liu, S. V., Lenkiewicz, E., Evers, L., Holley, T., Kiefer, J., Ruiz, C., Glatz, K., Bubendorf, L., Demeure, M. J., Eng, C., Ramanathan, R. K., Von Hoff, D. D. & Barrett, M., Dec 2012, In : Physical Biology. 9, 6, 065004.

Research output: Contribution to journalArticle

Neoplasms
DNA
Population
Neuroendocrine Tumors
Cholangiocarcinoma
44 Citations (Scopus)

Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities

Braggio, E. D., Dogan, A., Keats, J. J., Chng, W. J., Huang, G., Matthews, J. M., Maurer, M. J., Law, M. E., Bosler, D. S., Barrett, M., Lossos, I. S., Witzig, T. E. & Fonseca, R., May 2012, In : Modern Pathology. 25, 5, p. 651-660 10 p.

Research output: Contribution to journalArticle

Lymphoma
Marginal Zone B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 12
33 Citations (Scopus)

Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse

Braggio, E. D., Kay, N. E., Vanwier, S., Tschumper, R. C., Smoley, S., Eckel-Passow, J. E., Sassoon, T., Barrett, M., Van Dyke, D. L., Byrd, J. C., Jelinek, D. F., Shanafelt, T. D. & Fonseca, R., Jul 2012, In : Leukemia. 26, 7, p. 1698-1701 4 p.

Research output: Contribution to journalArticle

Clonal Evolution
Molecular Evolution
Human Genome
B-Cell Chronic Lymphocytic Leukemia
Chromosome Aberrations
9 Citations (Scopus)

Molecular characterization of a patient's small cell carcinoma of the ovary of the hypercalcemic type

Stephens, B., Anthony, S. P., Han, H., Kiefer, J., Hostetter, G., Barrett, M. & Von Hoff, D. D., 2012, In : Journal of Cancer. 3, 1, p. 58-66 9 p.

Research output: Contribution to journalArticle

Small Cell Carcinoma
Ovary
irinotecan
Gene Dosage
docetaxel
2011
88 Citations (Scopus)

Advancing a clinically relevant perspective of the clonal nature of cancer

Ruiz, C., Lenkiewicz, E., Evers, L., Holley, T., Robeson, A., Kiefer, J., Demeure, M. J., Hollingsworth, M. A., Shen, M., Prunkard, D., Rabinovitch, P. S., Zellweger, T., Mousses, S., Trent, J. M., Carpten, J. D., Bubendorf, L., Von Hoff, D. & Barrett, M., Jul 19 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12054-12059 6 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Population
Neoplasms
Biopsy
Androgens
28 Citations (Scopus)

Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer

Ruiz, C., Holz, D. R., Oeggerli, M., Schneider, S., Gonzales, I. M., Kiefer, J. M., Zellweger, T., Bachmann, A., Koivisto, P. A., Helin, H. J., Mousses, S., Barrett, M., Azorsa, D. O. & Bubendorf, L., Mar 2011, In : Journal of Pathology. 223, 4, p. 543-552 10 p.

Research output: Contribution to journalArticle

Vinculin
Prostatic Neoplasms
Cell Proliferation
Neoplasms
Gene Amplification
127 Citations (Scopus)

Copy number and targeted mutational analysis reveals novel somatic events in metastatic prostate tumors

Robbins, C. M., Tembe, W. A., Baker, A., Sinari, S., Moses, T. Y., Beckstrom-Sternberg, S., Beckstrom-Sternberg, J., Barrett, M., Long, J., Chinnaiyan, A., Lowey, J., Suh, E., Pearson, J. V., Craig, D. W., Agus, D. B., Pienta, K. J. & Carpten, J. D., Jan 2011, In : Genome Research. 21, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

Prostate
Neoplasms
Prostatic Neoplasms
Chromosome Mapping
Point Mutation
24 Citations (Scopus)

Genomic signatures of cancer: Basis for individualized risk assessment, selective staging and therapy

Baehner, F. L., Lee, M., Demeure, M. J., Bussey, K. J., Kiefer, J. A. & Barrett, M., May 1 2011, In : Journal of Surgical Oncology. 103, 6, p. 563-573 11 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Technology
Oligonucleotide Array Sequence Analysis
Real-Time Polymerase Chain Reaction
Molecular Biology
5 Citations (Scopus)

Integrated cytogenetic and high-resolution array CGH analysis of genomic alterations associated with MYCN amplification

Pandita, A., Bayani, J., Paderova, J., Marrano, P., Graham, C., Barrett, M., Prasad, M., Zielenska, M. & Squire, J. A., Apr 2011, In : Cytogenetic and Genome Research. 134, 1, p. 27-39 13 p.

Research output: Contribution to journalArticle

Cytogenetics
Spectral Karyotyping
Gene Amplification
Nucleic Acid Repetitive Sequences
Tumor Cell Line
2010
35 Citations (Scopus)

Deletion at fragile sites is a common and early event in Barrett's esophagus

Lai, L. A., Kostadinov, R., Barrett, M., Peiffer, D. A., Pokholok, D., Odze, R., Sanchez, C. A., Maley, C. C., Reid, B. J., Gunderson, K. L. & Rabinovitch, P. S., Aug 2010, In : Molecular Cancer Research. 8, 8, p. 1084-1094 11 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Proto-Oncogene Proteins c-fos
Loss of Heterozygosity
Biomarkers
DNA Breaks
57 Citations (Scopus)

Integrated preclinical and clinical development of mTOR inhibitors in pancreatic cancer

Garrido-Laguna, I., Tan, A. C., Uson, M., Angenendt, M., Ma, W. W., Villaroel, M. C., Zhao, M., Rajeshkumar, N. V., Jimeno, A., Donehower, R., Iacobuzio-Donahue, C., Barrett, M., Rudek, M. A., Rubio-Viqueira, B., Laheru, D. & Hidalgo, M., Aug 2010, In : British Journal of Cancer. 103, 5, p. 649-655 7 p.

Research output: Contribution to journalArticle

Sirolimus
Pancreatic Neoplasms
Heterografts
70-kDa Ribosomal Protein S6 Kinases
Neoplasms
2009
24 Citations (Scopus)

High-resolution genomic analysis in Waldenström's macroglobulinemia identifies disease-specific and common abnormalities with marginal zone lymphomas

Braggio, E. D., Keats, J., Leleu, X., Wier, S. V., Jimenez-Zepeda, V. H., Schop, R., Chesi, M., Barrett, M., Stewart, A. K., Dogan, A., Bergsagel, P. L., Ghobrial, I. & Fonseca, R., 2009, In : Clinical Lymphoma and Myeloma. 9, 1, p. 39-42 4 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Lymphoma
Chromosome Aberrations
Comparative Genomic Hybridization
Cytogenetic Analysis
106 Citations (Scopus)

Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-κB signaling pathways in Waldenström's macroglobulinemia

Braggio, E. D., Keats, J. J., Leleu, X., Van Wier, S., Jimenez-Zepeda, V. H., Valdez, R., Schop, R. F. J., Price-Troska, T., Henderson, K., Sacco, A., Azab, F., Greipp, P., Gertz, M., Hayman, S., Rajkumar, S. V., Carpten, J., Chesi, M., Barrett, M., Stewart, A. K., Dogan, A. & 3 others, Bergsagel, P. L., Ghobrial, I. M. & Fonseca, R., Apr 15 2009, In : Cancer Research. 69, 8, p. 3579-3588 10 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Mutation
Bone Marrow
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Uniparental Disomy
25 Citations (Scopus)

Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples

Hostetter, G., Kim, S. Y., Savage, S., Gooden, G. C., Barrett, M., Zhang, J., Alla, L., Watanabe, A., Einspahr, J., Prasad, A., Nickoloff, B. J., Carpten, J., Trent, J., Alberts, D. & Bittner, M., Oct 29 2009, In : Nucleic Acids Research. 38, 2, gkp881.

Research output: Contribution to journalArticle

Paraffin Embedding
DNA Fragmentation
Oligonucleotide Array Sequence Analysis
Formaldehyde
Exons
2008
47 Citations (Scopus)

Functional evidence implicating S100P in prostate cancer progression

Basu, G. D., Azorsa, D. O., Kiefer, J. A., Rojas, A. M., Tuzmen, S., Barrett, M., Trent, J. M., Kallioniemi, O. & Mousses, S., Jul 15 2008, In : International Journal of Cancer. 123, 2, p. 330-339 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Growth
Androgen Receptors
Apoptosis
Camptothecin
14 Citations (Scopus)

High definition cytogenetics and oligonucleotide aCGH analyses of cisplatin-resistant ovarian cancer cells

Prasad, M., Bernardini, M., Tsalenko, A., Marrano, P., Paderova, J., Lee, C. H., Ben-Dor, A., Barrett, M. & Squire, J. A., May 2008, In : Genes Chromosomes and Cancer. 47, 5, p. 427-436 10 p.

Research output: Contribution to journalArticle

Comparative Genomic Hybridization
Oligonucleotide Array Sequence Analysis
Cytogenetics
Ovarian Neoplasms
Cisplatin
2007
720 Citations (Scopus)

Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma

Keats, J. J., Fonseca, R., Chesi, M., Schop, R., Baker, A., Chng, W. J., Van Wier, S., Tiedemann, R., Shi, C. X., Sebag, M., Braggio, E. D., Henry, T., Zhu, Y. X., Fogle, H., Price-Troska, T., Ahmann, G., Mancini, C., Brents, L. A., Kumar, S. K., Greipp, P. & 10 others, Dispenzieri, A., Bryant, B., Mulligan, G., Bruhn, L., Barrett, M., Valdez, R., Trent, J., Stewart, A. K., Carpten, J. & Bergsagel, P. L., Aug 14 2007, In : Cancer Cell. 12, 2, p. 131-144 14 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 3
Multiple Myeloma
TNF Receptor-Associated Factor 2
Mutation
Gene Silencing
2005
4 Citations (Scopus)

Stacking the chips for biological discovery

Barrett, M., Jun 2005, In : Nature Genetics. 37, 6 SUPPL.

Research output: Contribution to journalArticle

Microarray Analysis