Projects per year
Fingerprint Dive into the research topics where Laurence J Miller is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Cholecystokinin Receptors
Medicine & Life Sciences
Cholecystokinin
Medicine & Life Sciences
G-Protein-Coupled Receptors
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
Secretin
Medicine & Life Sciences
Peptides
Medicine & Life Sciences
Cholecystokinin A Receptor
Medicine & Life Sciences
Labeling
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1983 2016
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure
Project: Research project
Ligands
Mutagenesis
G-Protein-Coupled Receptors
GTP-Binding Proteins
Molecular Models
GASTROINTESTINAL FUNCTIONS: NEUROPEPTIDERGIC CONTROL
Miller, L. J., [No Value], V. L. W., Zinsmeister, A. R., La Russo, N. F., Szurszewski, J. H., Kelly, K., Malagelada, J., [No Value], V. L. W., Yaksh, T. & Phillips, S.
9/30/84 → 11/30/90
Project: Research project
GASTROINTESTINAL FUNCTIONS: NEUROPEPTIDERGIC CONTROL
Miller, L. J., [No Value], V. L. W., Zinsmeister, A. R., Kelly, K., Larusso, N., Malagelada, J., Szurszewski, J., [No Value], V. L. W., Yaksh, T., Phillips, S. & La Russo, N. F.
9/30/84 → 11/30/85
Project: Research project
Research Output 1977 2019
1
Citation
(Scopus)
Characterization of farnesyl diphosphate farnesyl transferase 1 expression in cancer
Tüzmen, Ş., Hostetter, G., Watanabe, A., Ekmekçi, C., Carrigan, P. E., Shechter, I., Kallioniemi, O., Miller, L. J. & Mousses, S., Jan 1 2019, In : Personalized Medicine. 16, 1, p. 51-65 15 p.Research output: Contribution to journal › Article
Transferases
Neoplasms
Cholesterol
Enzymes
Metabolic Networks and Pathways
Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor
Desai, A. J., Mechin, I., Nagarajan, K., Valant, C., Wootten, D., Lam, P. C. H., Orry, A., Abagyan, R., Nair, A., Sexton, P. M., Christopoulos, A. & Miller, L. J., Mar 1 2019, In : Molecular Pharmacology. 95, 3, p. 245-259 15 p.Research output: Contribution to journal › Article
Cholecystokinin
Structure-Activity Relationship
Cholecystokinin Receptors
Peptides
Structural Models
6
Citations
(Scopus)
Changes in the plasma membrane in metabolic disease: impact of the membrane environment on G protein-coupled receptor structure and function
Desai, A. J. & Miller, L. J., Nov 1 2018, In : British Journal of Pharmacology. 175, 21, p. 4009-4025 17 p.Research output: Contribution to journal › Review article
Metabolic Diseases
G-Protein-Coupled Receptors
Cell Membrane
Membranes
Allosteric Regulation
27
Citations
(Scopus)
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor
Liang, Y. L., Khoshouei, M., Deganutti, G., Glukhova, A., Koole, C., Peat, T. S., Radjainia, M., Plitzko, J. M., Baumeister, W., Miller, L. J., Hay, D. L., Christopoulos, A., Reynolds, C. A., Wootten, D. & Sexton, P. M., Sep 27 2018, In : Nature. 561, 7724, p. 492-497 6 p.Research output: Contribution to journal › Article
Calcitonin Receptor-Like Protein
Calcitonin Gene-Related Peptide Receptors
Receptor Activity-Modifying Protein 1
Calcitonin Gene-Related Peptide
G-Protein-Coupled Receptors
15
Citations
(Scopus)
Crystal structure of the Frizzled 4 receptor in a ligand-free state
Yang, S., Wu, Y., Xu, T. H., de Waal, P. W., He, Y., Pu, M., Chen, Y., DeBruine, Z. J., Zhang, B., Zaidi, S. A., Popov, P., Guo, Y., Han, G. W., Lu, Y., Suino-Powell, K., Dong, S., Harikumar, K. G., Miller, L. J., Katritch, V., Xu, H. E. & 5 others, , Aug 30 2018, In : Nature. 560, 7720, p. 666-670 5 p.Research output: Contribution to journal › Letter
Frizzled Receptors
G-Protein-Coupled Receptors
Ligands
Gatekeeping
Mediator Complex