Projects per year
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Dive into the research topics where Laurence J Miller is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 2 Active
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Molecular basis of activation of the prototypic class B G protein-coupled secretin receptor
Miller, L. J. & Sexton, P.
National Institute of General Medical Sciences
9/1/19 → 8/31/22
Project: Research project
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Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure
Ardecky, R., Miller, L. J., Sergienko, E. & Miller, L. J.
National Heart, Lung, and Blood Institute
7/5/17 → 11/30/22
Project: Research project
Research output
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Development of a Testing Funnel for Identification of Small-Molecule Modulators Targeting Secretin Receptors
Dengler, D. G., Sun, Q., Holleran, J., Pollari, S., Beutel, J., Brown, B. T., Shinoki Iwaya, A., Ardecky, R., Harikumar, K. G., Miller, L. J. & Sergienko, E. A., Jan 2021, In: SLAS Discovery. 26, 1, p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated Cholesterol
Harikumar, K. G., Coudrat, T., Desai, A. J., Dong, M., Dengler, D. G., Furness, S. G. B., Christopoulos, A., Wootten, D., Sergienko, E. A., Sexton, P. M. & Miller, L. J., Dec 7 2021, In: Frontiers in Endocrinology. 12, 789957.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of small molecule positive allosteric modulators of the secretin receptor
Dengler, D. G., Harikumar, K. G., Pollari, S., Sun, Q., Brown, B. T., Shinoki-Iwaya, A., Ardecky, R., Miller, L. J. & Sergienko, E. A., Mar 2021, In: Biochemical Pharmacology. 185, 114451.Research output: Contribution to journal › Article › peer-review
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Evidence that specific interactions play a role in the cholesterol sensitivity of G protein-coupled receptors
Geiger, J., Sexton, R., Al-Sahouri, Z., Lee, M. Y., Chun, E., Harikumar, K. G., Miller, L. J., Beckstein, O. & Liu, W., Sep 1 2021, In: Biochimica et Biophysica Acta - Biomembranes. 1863, 9, 183557.Research output: Contribution to journal › Article › peer-review
Open Access -
Roles of Cholecystokinin in the Nutritional Continuum. Physiology and Potential Therapeutics
Miller, L. J., Harikumar, K. G., Wootten, D. & Sexton, P. M., Jun 2 2021, In: Frontiers in Endocrinology. 12, 684656.Research output: Contribution to journal › Review article › peer-review
Open Access