Laurence J Miller, MD

Professor, Phoenix/Scottsdale, AZ, Gastroenterology and Hepatology

Emailljm@mayo.edu

Source: Scopus
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Molecular basis of activation of the prototypic class B G protein-coupled secretin receptor
Miller, L. J.
National Institute of General Medical Sciences
Project: Research project
Activation of the Secretin Receptor as a Strategy for the Treatment of Heart Failure
Miller, L. J.
National Heart, Lung, and Blood Institute
Project: Research project
Universal positive allosteric modulators of CCK1R without intrinsic agonist activity for the treatment of obesity
Miller, L. J.
National Institute of Diabetes and Digestive and Kidney Diseases
Project: Research project
SECRETIN RECEPTOR STRUCTURE, FUNCTION, AND REGULATION
Miller, L. J., Kinney, L. & Kinney, L.
National Institute of Diabetes and Digestive and Kidney Diseases
2/1/95 → 7/31/15
Project: Research project
PILOT STUDY--MECHANISMS OF FECAL INCONTINENCE
Miller, L. J., [No Value], V. L. W., Zinsmeister, A. R., La Russo, N. F., Szurszewski, J. H., Kelly, K., Malagelada, J., [No Value], V. L. W., Yaksh, T. & Phillips, S.
National Institute of Diabetes and Digestive and Kidney Diseases
9/30/84 → 11/30/90
Project: Research project

13626 Citations
58 Scopus h-Index
328 Article
22 Review article
5 Chapter
4 Comment/debate
More

Development of a Testing Funnel for Identification of Small-Molecule Modulators Targeting Secretin Receptors
Dengler, D. G., Sun, Q., Holleran, J., Pollari, S., Beutel, J., Brown, B. T., Shinoki Iwaya, A., Ardecky, R., Harikumar, K. G., Miller, L. J. & Sergienko, E. A., Jan 2021, In: SLAS Discovery. 26, 1, p. 1-16 16 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Discovery of small molecule positive allosteric modulators of the secretin receptor
Dengler, D. G., Harikumar, K. G., Pollari, S., Sun, Q., Brown, B. T., Shinoki-Iwaya, A., Ardecky, R., Miller, L. J. & Sergienko, E. A., Mar 2021, In: Biochemical Pharmacology. 185, 114451.
Research output: Contribution to journal › Article › peer-review
Evidence that specific interactions play a role in the cholesterol sensitivity of G protein-coupled receptors
Geiger, J., Sexton, R., Al-Sahouri, Z., Lee, M. Y., Chun, E., Harikumar, K. G., Miller, L. J., Beckstein, O. & Liu, W., 2021, (Accepted/In press) In: Biochimica et Biophysica Acta - Biomembranes. 183557.
Research output: Contribution to journal › Article › peer-review
Single-molecule FRET imaging of GPCR dimers in living cells
Asher, W. B., Geggier, P., Holsey, M. D., Gilmore, G. T., Pati, A. K., Meszaros, J., Terry, D. S., Mathiasen, S., Kaliszewski, M. J., McCauley, M. D., Govindaraju, A., Zhou, Z., Harikumar, K. G., Jaqaman, K., Miller, L. J., Smith, A. W., Blanchard, S. C. & Javitch, J. A., Apr 2021, In: Nature Methods. 18, 4, p. 397-405 9 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Activation of the GLP-1 receptor by a non-peptidic agonist
Zhao, P., Liang, Y. L., Belousoff, M. J., Deganutti, G., Fletcher, M. M., Willard, F. S., Bell, M. G., Christe, M. E., Sloop, K. W., Inoue, A., Truong, T. T., Clydesdale, L., Furness, S. G. B., Christopoulos, A., Wang, M. W., Miller, L. J., Reynolds, C. A., Danev, R., Sexton, P. M. & Wootten, D., Jan 16 2020, In: Nature. 577, 7790, p. 432-436 5 p.
Research output: Contribution to journal › Article › peer-review
39 Scopus citations