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Research Output 2003 2019

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Article
2019
1 Citation (Scopus)

Integrated RNA-seq and ChIP-seq analysis reveals a feed-forward loop regulating H3K9ac and key labor drivers in human placenta

Wang, B., Wang, P., Parobchak, N., Treff, N., Tao, X., Wang, J. & Rosen, T., Jan 15 2019, In : Placenta. 76, p. 40-50 11 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Placenta
Chromatin
Trophoblasts
Genes

MetaMarker: A pipeline for de novo discovery of novel metagenomic biomarkers

Koohi-Moghadam, M., Borad, M. J., Tran, N. L., Swanson, K. R., Boardman, L. A., Sun, H. & Wang, J., Oct 1 2019, In : Bioinformatics. 35, 19, p. 3812-3814 3 p.

Research output: Contribution to journalArticle

Metagenomics
Biomarkers
Colorectal Cancer
Pipelines
Metagenome
2018
4 Citations (Scopus)

Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer

Mouchli, M. A., Ouk, L., Scheitel, M. R., Chaudhry, A. P., Felmlee-Devine, D., Grill, D. E., Rashtak, S., Wang, P., Wang, J., Chaudhry, R., Smyrk, T. C., Oberg, A. L., Druliner, B. R. & Boardman, L. A., Feb 28 2018, In : World Journal of Gastroenterology. 24, 8, p. 905-916 12 p.

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Adenoma
Colorectal Neoplasms
Risk Management
11 Citations (Scopus)

Evaluation of tools for highly variable gene discovery from single-cell RNA-seq data

Yip, S. H., Sham, P. C. & Wang, J., Mar 27 2018, In : Briefings in bioinformatics. 20, 4, p. 1583-1589 7 p.

Research output: Contribution to journalArticle

Open Access
RNA Sequence Analysis
Genetic Association Studies
RNA
Genes
Gene expression
5 Citations (Scopus)

GWAS4D: Multidimensional analysis of context-specific regulatory variant for human complex diseases and traits

Huang, D., Yi, X., Zhang, S., Zheng, Z., Wang, P., Xuan, C., Sham, P. C., Wang, J. & Li, M. J., Jul 2 2018, In : Nucleic Acids Research. 46, W1, p. W114-W120

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genomics
Epigenomics
Single Nucleotide Polymorphism
Coronary Artery Disease

Inferring RNA sequence preferences for poorly studied RNA-binding proteins based on co-evolution

Yang, S., Wang, J. & Ng, R. T., Mar 12 2018, In : BMC Bioinformatics. 19, 1, 96.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Coevolution
RNA
Protein
Computational methods
6 Citations (Scopus)

Integrated transcriptomic and regulatory network analyses identify microRNA-200c as a novel repressor of human pluripotent stem cell-derived cardiomyocyte differentiation and maturation

Poon, E. N. Y., Hao, B., Guan, D., Jun Li, M., Lu, J., Yang, Y., Wu, B., Wu, S. C. M., Webb, S. E., Liang, Y., Miller, A. L., Yao, X., Wang, J., Yan, B. & Boheler, K. R., May 1 2018, In : Cardiovascular Research. 114, 6, p. 894-906 13 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
MicroRNAs
Cardiac Myocytes
Transcription Factors
Gene Regulatory Networks
11 Citations (Scopus)

Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials

Yang, X., Koohi-Moghadam, M., Wang, R., Chang, Y. Y., Woo, P. C. Y., Wang, J., Li, H. & Sun, H., Jan 1 2018, In : PLoS Biology. 16, 1, e2003887.

Research output: Contribution to journalArticle

Metallochaperones
urease inhibitors
Urease
urease
anti-infective agents
5 Citations (Scopus)

Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations

Druliner, B. R., Wang, P., Bae, T., Baheti, S., Slettedahl, S., Mahoney, D., Vasmatzis, N., Xu, H., Kim, M., Bockol, M., O'Brien, D., Grill, D., Warner, N., Munoz-Gomez, M., Kossick, K., Johnson, R., Mouchli, M., Felmlee-Devine, D., Washechek-Aletto, J., Smyrk, T. C. & 6 others, Oberg, A. L., Wang, J., Chia, N. D., Abyzov, A., Ahlquist, D. & Boardman, L. A., Dec 1 2018, In : Scientific Reports. 8, 1, 3161.

Research output: Contribution to journalArticle

Polyps
Transcriptome
Adenoma
Genome
Neoplasms

Novel Neural Network Approach to Predict Drug-Target Interactions Based on Drug Side Effects and Genome-Wide Association Studies

Prinz, J., Koohi-Moghadam, M., Sun, H., Kocher, J-P. & Wang, J., Jan 1 2018, (Accepted/In press) In : Human Heredity. p. 79-91 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Drug-Related Side Effects and Adverse Reactions
Drug Interactions
Pharmaceutical Preparations
Databases
2017
10 Citations (Scopus)

Absence of NUCKS augments paracrine effects of mesenchymal stem cells-mediated cardiac protection

Zhang, Y., Chiu, S., Liang, X., Chai, Y. H., Qin, Y., Wang, J., Li, X., Qiu, B., Tergaonkar, V., Tse, H. F. & Lian, Q., Jul 1 2017, In : Experimental Cell Research. 356, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Bone Marrow
Myocardial Infarction
Casein Kinases
CDC2 Protein Kinase
8 Citations (Scopus)

Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction

Yu, Y., Tang, J., Shen, Y., Chen, G., Wan, Q., Wang, K., Zhang, J., Qin, J., Liu, G., Zuo, S., Tao, B., Yu, Y., Wang, J. & Lazarus, M., Mar 3 2017, In : Nature Communications. 8, 14656.

Research output: Contribution to journalArticle

myocardial infarction
macrophages
Macrophages
healing
Dinoprostone
9 Citations (Scopus)

An integrative method to decode regulatory logics in gene transcription

Yan, B., Guan, D., Wang, C., Wang, J., He, B., Qin, J., Boheler, K. R., Lu, A., Zhang, G. & Zhu, H., Dec 1 2017, In : Nature Communications. 8, 1, 1044.

Research output: Contribution to journalArticle

Transcription
genes
logic
Transcription Factors
Genes
17 Citations (Scopus)

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

Seow, W. J., Matsuo, K., Hsiung, C. A., Shiraishi, K., Song, M., NamKim, H., Wong, M. P., Hong, Y. C., Dean Hosgood, H., Wang, Z., Chang, I. S., Wang, J. C., Chatterjee, N., Tucker, M., Wei, H., Mitsudomi, T., Zheng, W., Kim, J. H., Zhou, B., Caporaso, N. E. & 166 others, Albanes, D., Shin, M. H., Chung, L. P., An, S. J., Wang, P., Zheng, H., Yatabe, Y., Zhang, X. C., Kim, Y. T., Shu, X. O., Kim, Y. C., Bassig, B. A., Chang, J., Man Ho, J. C., Ji, B. T., Kubo, M., Daigo, Y., Ito, H., Momozawa, Y., Ashikawa, K., Kamatani, Y., Honda, T., Sakamoto, H., Kunitoh, H., Tsuta, K., Watanabe, S. I., Nokihara, H., Miyagi, Y., Nakayama, H., Matsumoto, S., Tsuboi, M., Goto, K., Yin, Z., Shi, J., Takahashi, A., Goto, A., Minamiya, Y., Shimizu, K., Tanaka, K., Wu, T., Wei, F., Wong, J. Y. Y., Matsuda, F., Su, J., Kim, Y. H., Oh, I. J., Song, F., Lee, V. H. F., Su, W. C., Chen, Y. M., Chang, G. C., Chen, K. Y., Huang, M. S., Yang, P. C., Lin, H. C., Xiang, Y. B., Seow, A., Park, J. Y., Kweon, S. S., Chen, C. J., Li, H., Gao, Y. T., Wu, C., Qian, B., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Wang, W. C., Chung, C. C., Lawrence, C., Burdett, L., Yeager, M., Jacobs, K. B., Hutchinson, A., Berndt, S. I., He, X., Wu, W., Wang, J., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Liu, L., Kang, C. H., Hu, L., Chen, C. H., Yang, T. Y., Xu, J., Guan, P., Tan, W., Wang, C. L., Loon Sihoe, A. D., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Cai, Q., Lin, C. C., Park, I. K., Xu, P., Dong, J., Kim, C., He, Q., Perng, R. P., Chen, C. Y., Vermeulen, R., Wu, J., Lim, W. Y., Chen, K. C., Chan, J. K. C., Chu, M., Li, Y. J., Li, J., Chen, H., Yu, C. J., Jin, L., Lo, Y. L., Chen, Y. H., Fraumeni, J. F., Liu, J., Yamaji, T., Yang, Y., Hicks, B., Wyatt, K., Li, S. A., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Li, X., Ren, Y., Cui, P., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Jiang, G., Fei, K., Wu, G., Chien, L. H., Chen, H. L., Su, Y. C., Tsai, F. Y., Chen, Y. S., Yu, J., Stevens, V. L., Laird-Offringa, I. A., Marconett, C. N., Lin, D., Chen, K., Wu, Y. L., Landi, M. T., Shen, H., Rothman, N., Kohno, T., Chanock, S. J. & Lan, Q., 2017, In : Human Molecular Genetics. 26, 2, p. 454-465 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Smoking
Mutation
Population
Single Nucleotide Polymorphism
15 Citations (Scopus)

Cepip: Context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes

Li, M. J., Li, M., Liu, Z., Yan, B., Pan, Z., Huang, D., Liang, Q., Ying, D., Xu, F., Yao, H., Wang, P., Kocher, J-P., Xia, Z., Sham, P. C., Liu, J. S. & Wang, J., Mar 16 2017, In : Genome Biology. 18, 1, 52.

Research output: Contribution to journalArticle

prioritization
Epigenomics
epigenetics
Genome-Wide Association Study
gene
2 Citations (Scopus)

Evolution of Drug-resistant Acinetobacter baumannii after DCD Renal Transplantation

Jiang, H., Cao, L., Qu, L., Qu, T., Liu, G., Wang, R., Li, B., Wang, Y., Ying, C., Chen, M., Lu, Y., Feng, S., Xiao, Y., Wang, J., Wu, J. & Chen, J., Dec 1 2017, In : Scientific Reports. 7, 1, 1968.

Research output: Contribution to journalArticle

Acinetobacter baumannii
Kidney Transplantation
Pharmaceutical Preparations
Disease Outbreaks
Disk Diffusion Antimicrobial Tests
12 Citations (Scopus)

Exploring genetic associations with ceRNA regulation in the human genome

Li, M. J., Zhang, J., Liang, Q., Xuan, C., Wu, J., Jiang, P., Li, W., Zhu, Y., Wang, P., Fernandez, D., Shen, Y., Chen, Y., Kocher, J-P., Yu, Y., Sham, P. C., Wang, J., Liu, J. S. & Liu, X. S., 2017, In : Nucleic Acids Research. 45, 10, p. 5653-5665 13 p.

Research output: Contribution to journalArticle

Human Genome
MicroRNAs
RNA
Quantitative Trait Loci
Genome-Wide Association Study
9 Citations (Scopus)

Integration of fluorescence imaging with proteomics enables visualization and identification of metallo-proteomes in living cells

Lai, Y. T., Yang, Y., Hu, L., Cheng, T., Chang, Y. Y., Koohi-Moghadam, M., Wang, Y., Xia, J., Wang, J., Li, H. & Sun, H., Jan 1 2017, In : Metallomics. 9, 1, p. 38-47 10 p.

Research output: Contribution to journalArticle

Optical Imaging
Metalloproteins
Proteome
Proteomics
Carrier Proteins
22 Citations (Scopus)

Integrative approach for the analysis of the proteome-wide response to bismuth drugs in: Helicobacter pylori

Wang, Y., Hu, L., Xu, F., Quan, Q., Lai, Y. T., Xia, W., Yang, Y., Chang, Y. Y., Yang, X., Chai, Z., Wang, J., Chu, I. K., Li, H. & Sun, H., 2017, In : Chemical Science. 8, 6, p. 4626-4633 8 p.

Research output: Contribution to journalArticle

Bismuth
Proteome
Pharmaceutical Preparations
Pathogens
Bioassay
15 Citations (Scopus)

Linnorm: improved statistical analysis for single cell RNA-seq expression data

Yip, S. H., Wang, P., Kocher, J-P., Sham, P. C. & Wang, J., Dec 15 2017, In : Nucleic Acids Research. 45, 22, p. e179

Research output: Contribution to journalArticle

Single-Cell Analysis
RNA Sequence Analysis
RNA
Noise
Cluster Analysis
24 Citations (Scopus)

Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR-NF-k B pathway in human monocytes

Zhang, D. D., Wang, W. T., Xiong, J., Xie, X. M., Cui, S. S., Zhao, Z. G., Li, M. J., Zhang, Z. Q., Hao, D. L., Zhao, X., Li, Y. J., Wang, J., Chen, H. Z., Lv, X. & Liu, D. P., Apr 10 2017, In : Scientific Reports. 7, 46204.

Research output: Contribution to journalArticle

Long Noncoding RNA
Lipocalin 1
Aryl Hydrocarbon Receptors
Monocytes
Inflammation
2 Citations (Scopus)

MTCTScan: A comprehensive platform for annotation and prioritization of mutations affecting drug sensitivity in cancers

Li, M. J., Yao, H., Huang, D., Liu, H., Liu, Z., Xu, H., Qin, Y., Prinz, J., Xia, W., Wang, P., Yan, B., Tran, N., Kocher, J-P., Sham, P. C. & Wang, J., Jul 3 2017, In : Nucleic Acids Research. 45, W1, p. W215-W221

Research output: Contribution to journalArticle

Mutation
Pharmaceutical Preparations
Neoplasms
Therapeutics
Precision Medicine
9 Citations (Scopus)

NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma

Xiao, Z. J., Liu, J., Wang, S. Q., Zhu, Y., Gao, X. Y., Tin, V. P. C., Qin, J., Wang, J. & Wong, M. P., Jul 24 2017, In : eLife. 6, e26733.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Tumors
Phenotype
Lung Neoplasms
Neoplasms
10 Citations (Scopus)

Robust and rapid algorithms facilitate large-scale whole genome sequencing downstream analysis in an integrative framework

Li, M., Li, J., Li, M. J., Pan, Z., Hsu, J. S., Liu, D. J., Zhan, X., Wang, J., Youqiang, S. & Sham, P. C., May 19 2017, In : Nucleic Acids Research. 45, 9, e75.

Research output: Contribution to journalArticle

Genotype
Genome
Molecular Sequence Annotation
Quality Control
Alleles
3 Citations (Scopus)

Tacrolimus dose requirement based on the CYP3A5 genotype in renal transplant patients

Qu, L., Lu, Y., Ying, M., Li, B., Weng, C., Xie, Z., Liang, L., Lin, C., Yang, X., Feng, S., Wang, Y., Shen, X., Zhou, Q., Chen, Y., Chen, Z., Wu, J., Lin, W., Shen, Y., Qin, J., Xu, H. & 5 others, Xu, F., Wang, J., Chen, J., Jiang, H. & Huang, H., Jan 1 2017, In : Oncotarget. 8, 46, p. 81285-81294 10 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Tacrolimus
Genotype
Transplants
Kidney
10 Citations (Scopus)

UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq

Sun, Z. D., Nair, A., Chen, X., Prodduturi, N., Wang, J. & Kocher, J-P., Dec 1 2017, In : Scientific Reports. 7, 1, 14196.

Research output: Contribution to journalArticle

Long Noncoding RNA
RNA
Genes
Research Personnel
Phenotype
1 Citation (Scopus)

Whole-genome analysis of an extensive drug-resistant acinetobacter baumannii ST195 isolate from a recipient after DCD renal transplantation in China

Jiang, H., Cao, L., Shen, Q., Qu, L., Jiang, Y., Qu, T., Zhang, J., Lu, Y., Li, B., Zhu, C., Liu, G., Wang, R., Chen, M., Wang, Y., Wang, Y., Feng, S., Wang, J., Yu, Y., Wu, J. & Chen, J., Jan 1 2017, In : Kidney and Blood Pressure Research. 42, 6, p. 1247-1257 11 p.

Research output: Contribution to journalArticle

Acinetobacter baumannii
Kidney Transplantation
China
Genome
Pharmaceutical Preparations
2016
69 Citations (Scopus)

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Sampson, J. N., Wheeler, W. A., Yeager, M., Panagiotou, O., Wang, Z., Berndt, S. I., Lan, Q., Abnet, C. C., Amundadottir, L. T., Figueroa, J. D., Landi, M. T., Mirabello, L., Savage, S. A., Taylor, P. R., De Vivo, I., McGlynn, K. A., Purdue, M. P., Rajaraman, P., Adami, H. O., Ahlbom, A. & 388 others, Albanes, D., Amary, M. F., An, S. J., Andersson, U., Andriole, G., Andrulis, I. L., Angelucci, E., Ansell, S. M., Arici, C., Armstrong, B. K., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Becker, N., Benavente, Y., Benhamou, S., Berg, C., Van Den Berg, D., Bernstein, L., Bertrand, K. A., Birmann, B. M., Black, A., Shanafelt, T. D., Boffetta, P., Boutron-Ruault, M. C., Bracci, P. M., Brinton, L., Brooks-Wilson, A. R., Bueno-De-Mesquita, H. B., Burdett, L., Buring, J., Butler, M. A., Cai, Q., Cancel-Tassin, G., Canzian, F., Carrato, A., Carreon, T., Carta, A., Chan, J. K. C., Chang, E. T., Chang, G. C., Chang, I. S., Chang, J., Chang-Claude, J., Chen, C. J., Chen, C. Y., Chen, C., Chen, C. H., Chen, C., Chen, H., Chen, K., Chen, K. Y., Chen, K. C., Chen, Y., Chen, Y. H., Chen, Y. S., Chen, Y. M., Chien, L. H., Chirlaque, M. D., Choi, J. E., Choi, Y. Y., Chow, W. H., Chung, C. C., Clavel, J., Clavel-Chapelon, F., Cocco, P., Colt, J. S., Comperat, E., Conde, L., Connors, J. M., Conti, D., Cortessis, V. K., Cotterchio, M., Cozen, W., Crouch, S., Crous-Bou, M., Cussenot, O., Davis, F. G., Ding, T., Diver, W. R., Dorronsoro, M., Dossus, L., Duell, E. J., Ennas, M. G., Erickson, R. L., Feychting, M., Flanagan, A. M., Foretova, L., Fraumeni, J. F., Freedman, N. D., Freeman, L. E. B., Fuchs, C., Gago-Dominguez, M., Gallinger, S., Gao, Y. T., Gapstur, S. M., Garcia-Closas, M., García-Closas, R., Gascoyne, R. D., Gastier-Foster, J., Gaudet, M. M., Gaziano, J. M., Giffen, C., Giles, G. G., Giovannucci, E., Glimelius, B., Goggins, M., Gokgoz, N., Goldstein, A. M., Gorlick, R., Gross, M., Grubb, R., Gu, J., Guan, P., Gunter, M., Guo, H., Habermann, T. M., Haiman, C. A., Halai, D., Hallmans, G., Hassan, M., Hattinger, C., He, Q., He, X., Helzlsouer, K., Henderson, B., Henriksson, R., Hjalgrim, H., Hoffman-Bolton, J., Hohensee, C., Holford, T. R., Holly, E. A., Hong, Y. C., Hoover, R. N., Horn-Ross, P. L., Hosain, G. M. M., Hosgood, H. D., Hsiao, C. F., Hu, N., Hu, W., Hu, Z., Huang, M. S., Huerta, J. M., Hung, J. Y., Hutchinson, A., Inskip, P. D., Jackson, R. D., Jacobs, E. J., Jenab, M., Jeon, H. S., Ji, B. T., Jin, G., Jin, L., Johansen, C., Johnson, A., Jung, Y. J., Kaaks, R., Kamineni, A., Kane, E., Kang, C. H., Karagas, M. R., Kelly, R. S., Khaw, K. T., Kim, C., Kim, H. N., Kim, J. H., Kim, J. S., Kim, Y. H., Kim, Y. T., Kim, Y. C., Kitahara, C. M., Klein, A. P., Klein, R. J., Kogevinas, M., Kohno, T., Kolonel, L. N., Kooperberg, C., Kricker, A., Krogh, V., Kunitoh, H., Kurtz, R. C., Kweon, S. S., La Croix, A., Lawrence, C., Lecanda, F., Lee, V. H. F., Li, D., Li, H., Li, J., Li, Y. J., Li, Y., Liao, L. M., Liebow, M., Lightfoot, T., Lim, W. Y., Lin, C. C., Lin, D., Lindstrom, S., Linet, M. S., Link, B. K., Liu, C., Liu, J., Liu, L., Ljungberg, B., Lloreta, J., Di Lollo, S., Lu, D., Lund, E., Malats, N., Mannisto, S., Marchand, L. L., Marina, N., Masala, G., Mastrangelo, G., Matsuo, K., Maynadie, M., McKay, J., McKean-Cowdin, R., Melbye, M., Melin, B. S., Michaud, D. S., Mitsudomi, T., Monnereau, A., Montalvan, R., Moore, L. E., Mortensen, L. M., Nieters, A., North, K. E., Novak, A. J., Oberg, A. L., Offit, K., Oh, I. J., Olson, S. H., Palli, D., Pao, W., Park, I. K., Park, J. Y., Park, K. H., Patiño-Garcia, A., Pavanello, S., Peeters, P. H. M., Perng, R. P., Peters, U., Petersen, G. M., Picci, P., Pike, M. C., Porru, S., Prescott, J., Prokunina-Olsson, L., Qian, B., Qiao, Y. L., Rais, M., Riboli, E., Riby, J., Risch, H. A., Rizzato, C., Rodabough, R., Roman, E., Roupret, M., Ruder, A. M., De Sanjose, S., Scelo, G., Schned, A., Schumacher, F., Schwartz, K., Schwenn, M., Scotlandi, K., Seow, A., Serra, C., Serra, M., Sesso, H. D., Setiawan, V. W., Severi, G., Severson, R. K., Shanafelt, T. D., Shen, H., Shen, W., Shin, M. H., Shiraishi, K., Shu, X. O., Siddiq, A., Sierrasesúmaga, L., Sihoe, A. D. L., Skibola, C. F., Smith, A., Smith, M. T., Southey, M. C., Spinelli, J. J., Staines, A., Stampfer, M., Stern, M. C., Stevens, V. L., Stolzenberg-Solomon, R. S., Su, J., Su, W. C., Sund, M., Sung, J. S., Sung, S. W., Tan, W., Tang, W., Tardón, A., Thomas, D., Thompson, C. A., Tinker, L. F., Tirabosco, R., Tjønneland, A., Travis, R. C., Trichopoulos, D., Tsai, F. Y., Tsai, Y. H., Tucker, M., Turner, J., Vajdic, C. M., Vermeulen, R. C. H., Villano, D. J., Vineis, P., Virtamo, J., Visvanathan, K., Wactawski-Wende, J., Wang, C., Wang, C. L., Wang, J. C., Wang, J., Wei, F., Weiderpass, E., Weiner, G. J., Weinstein, S., Wentzensen, N., White, E., Witzig, T. E., Wolpin, B. M., Wong, M. P., Wu, C., Wu, G., Wu, J., Wu, T., Wu, W., Wu, X., Wu, Y. L., Wunder, J. S., Xiang, Y. B., Xu, J., Xu, P., Yang, P. C., Yang, T. Y., Ye, Y., Yin, Z., Yokota, J., Yoon, H. I., Yu, C. J., Yu, H., Yu, K., Yuan, J. M., Zelenetz, A., Zeleniuch-Jacquotte, A., Zhang, X. C., Zhang, Y., Zhao, X., Zhao, Z., Zheng, H., Zheng, T., Zheng, W., Zhou, B., Zhu, M., Zucca, M., Boca, S. M., Cerhan, J. R., Ferri, G. M., Hartge, P., Hsiung, C. A., Magnani, C., Miligi, L., Morton, L. M., Smedby, K. E., Teras, L. R., Vijai, J., Wang, S. S., Brennan, P., Caporaso, N. E., Hunter, D. J., Kraft, P., Rothman, N., Silverman, D. T., Slager, S. L., Chanock, S. J. & Chatterjee, N., 2016, In : Journal of the National Cancer Institute. 107, 12, djv279.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Smoking
Neoplasms
Lung Neoplasms
Confidence Intervals

Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest

Bildsoe, H., Fan, X., Wilkie, E. E., Ashoti, A., Jones, V. J., Power, M., Qin, J., Wang, J., Tam, P. P. L. & Loebel, D. A. F., Dec 1 2016, In : Data in Brief. 9, p. 372-375 4 p.

Research output: Contribution to journalArticle

Neural Crest
Mesoderm
Transcriptome
Embryonic Structures
Genes
30 Citations (Scopus)

Five endometrial cancer risk loci identified through genome-wide association analysis

Cheng, T. H. T., Thompson, D. J., O'Mara, T. A., Painter, J. N., Glubb, D. M., Flach, S., Lewis, A., French, J. D., Freeman-Mills, L., Church, D., Gorman, M., Martin, L., Hodgson, S., MWebb, P., Attia, J., Holliday, E. G., McEvoy, M., Scott, R. J., KHenders, A., Martin, N. G. & 67 others, Montgomery, G. W., Nyholt, D. R., Ahmed, S., Healey, C. S., Shah, M., Dennis, J., Fasching, P. A., Beckmann, M. W., Hein, A., Ekici, A. B., Hall, P., Czene, K., Darabi, H., Li, J., Dörk, T., Dürst, M., Hillemanns, P., Runnebaum, I., Amant, F., Schrauwen, S., Zhao, H., Lambrechts, D., Depreeuw, J., Dowdy, S. C., Goode, E. L., Fridley, B. L., Winham, S. J., NjØlstad, T. S., Salvesen, H. B., Trovik, J., Werner, H. M. J., Ashton, K., Otton, G., Proietto, T., Liu, T., Mints, M., Tham, E., Li, M. J., Yip, S. H., Wang, J., KBolla, M., Michailidou, K., Wang, Q., Tyrer, J. P., Dunlop, M., Houlston, R., Palles, C., Hopper, J. L., Peto, J., Swerdlow, A. J., Burwinkel, B., Brenner, H., Meindl, A., Brauch, H., Lindblom, A., Chang-Claude, J., Couch, F. J., Giles, G. G., Kristensen, V. N., Cox, A., MCunningham, J., Pharoah, P. D. P., Dunning, A. M., Edwards, S. L., Easton, D. F., Tomlinson, I. & Spurdle, A. B., Jun 1 2016, In : Nature Genetics. 48, 6, p. 667-674 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Endometrial Neoplasms
Meta-Analysis
Genome
Nucleic Acid Regulatory Sequences
7 Citations (Scopus)

Functional networks of aging markers in the glomeruli of IgA nephropathy: A new therapeutic opportunity

Jiang, H., Liang, L., Qin, J., Lu, Y., Li, B., Wang, Y., Lin, C., Zhou, Q., Feng, S., Yip, S. H., Xu, F., Lai, E. Y., Wang, J. & Chen, J., Jun 7 2016, In : Oncotarget. 7, 23, p. 33616-33626 11 p.

Research output: Contribution to journalArticle

Immunoglobulin A
Neutrophils
Telomere
Therapeutics
DNA Damage
69 Citations (Scopus)

GWASdb v2: An update database for human genetic variants identified by genome-wide association studies

Li, M. J., Liu, Z., Wang, P., Wong, M. P., Nelson, M. R., Kocher, J-P., Yeager, M., Sham, P. C., Chanock, S. J., Xia, Z. & Wang, J., 2016, In : Nucleic Acids Research. 44, D1, p. D869-D876

Research output: Contribution to journalArticle

Genome-Wide Association Study
Medical Genetics
Single Nucleotide Polymorphism
Databases
Publications
21 Citations (Scopus)

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Wang, Z., Seow, W. J., Shiraishi, K., Hsiung, C. A., Matsuo, K., Liu, J., Chen, K., Yamji, T., Yang, Y., Chang, I. S., Wu, C., Hong, Y. C., Burdett, L., Wyatt, K., Chung, C. C., Li, S. A., Yeager, M., Hutchinson, A., Hu, W., Caporaso, N. & 130 others, Landi, M. T., Chatterjee, N., Song, M., Fraumeni, J. F., Kohno, T., Yokota, J., Kunitoh, H., Ashikawa, K., Momozawa, Y., Daigo, Y., Mitsudomi, T., Yatabe, Y., Hida, T., Hu, Z., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Yin, Z., Li, X., Ren, Y., Guan, P., Chang, J., Tan, W., Chen, C. J., Chang, G. C., Tsai, Y. H., Su, W. C., Chen, K. Y., Huang, M. S., Chen, Y. M., Zheng, H., Li, H., Cui, P., Guo, H., Xu, P., Liu, L., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Jiang, G., Fei, K., Park, J. Y., Kim, Y. H., Sung, J. S., Park, K. H., Kim, Y. T., Jung, Y. J., Kang, C. H., Park, I. K., Kim, H. N., Jeon, H. S., Choi, J. E., Choi, Y. Y., Kim, J. H., Oh, I. J., Kim, Y. C., Sung, S. W., Kim, J. S., Yoon, H. I., Kweon, S. S., Shin, M. H., Seow, A., Chen, Y., Lim, W. Y., Liu, J., Wong, M. P., Lee, V. H. F., Bassig, B. A., Tucker, M., Berndt, S. I., Chow, W. H., Ji, B. T., Wang, J., Xu, J., Sihoe, A. D. L., Ho, J. C. M., Chan, J. K. C., Wang, J. C., Lu, D., Zhao, X., Zhao, Z., Wu, J., Chen, H., Jin, L., Wei, F., Wu, G., An, S. J., Zhang, X. C., Su, J., Wu, Y. L., Gao, Y. T., Xiang, Y. B., He, X., Li, J., Zheng, W., Shu, X. O., Cai, Q., Klein, R., Pao, W., Lawrence, C., Hosgood, H. D., Hsiao, C. F., Chien, L. H., Chen, Y. H., Chen, C. H., Wang, W. C., Chen, C. Y., Wang, C. L., Yu, C. J., Chen, H. L., Su, Y. C., Tsai, F. Y., Chen, Y. S., Li, Y. J., Yang, T. Y., Lin, C. C., Yang, P. C., Wu, T., Lin, D., Zhou, B., Yu, J., Shen, H., Kubo, M., Chanock, S. J., Rothman, N. & Lan, Q., Feb 1 2016, In : Human Molecular Genetics. 25, 3, p. 620-629 10 p., ddv494.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Meta-Analysis
Lung Neoplasms
Smoking
Alleles
19 Citations (Scopus)

Predicting regulatory variants with composite statistic

Li, M. J., Pan, Z., Liu, Z., Wu, J., Wang, P., Zhu, Y., Xu, F., Xia, Z., Sham, P. C., Kocher, J-P., Li, M., Liu, J. S. & Wang, J., Sep 15 2016, In : Bioinformatics. 32, 18, p. 2729-2736 8 p.

Research output: Contribution to journalArticle

Precision Medicine
Genomics
Statistic
Virulence
Composite
8 Citations (Scopus)

Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance

Bildsoe, H., Fan, X., Wilkie, E. E., Ashoti, A., Jones, V. J., Power, M., Qin, J., Wang, J., Tam, P. P. L. & Loebel, D. A. F., Oct 1 2016, In : Developmental Biology. 418, 1, p. 189-203 15 p.

Research output: Contribution to journalArticle

Mesoderm
Cell Communication
Maintenance
Extracellular Matrix
Basic Helix-Loop-Helix Transcription Factors
2015
3 Citations (Scopus)

Bayesian detection of embryonic gene expression onset in C. elegans

Hu, J., Zhao, Z., Yalamanchili, H. K., Wang, J., Ye, K. & Fan, X., Jun 1 2015, In : Annals of Applied Statistics. 9, 2, p. 950-968 19 p.

Research output: Contribution to journalArticle

Gene expression
Gene Expression
Confocal
Embryo
Change-point Model
15 Citations (Scopus)

Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography

Wang, Y., Tsang, C. N., Xu, F., Kong, P. W., Hu, L., Wang, J., Chu, I. K., Li, H. & Sun, H., 2015, In : Chemical Communications. 51, 92, p. 16479-16482 4 p.

Research output: Contribution to journalArticle

Affinity chromatography
Bismuth
Affinity Chromatography
Helicobacter pylori
Peptides
11 Citations (Scopus)

ChIP-Array 2: Integrating multiple omics data to construct gene regulatory networks

Wang, P., Qin, J., Qin, Y., Zhu, Y., Wang, L. Y., Li, M. J., Zhang, M. Q. & Wang, J., 2015, In : Nucleic Acids Research. 43, W1, p. W264-W269

Research output: Contribution to journalArticle

Gene Regulatory Networks
Chromatin
Transcription Factors
Histone Code
Transcriptome
6 Citations (Scopus)

Chronic Cardiovascular Disease-Associated Gene Network Analysis in Human Umbilical Vein Endothelial Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Yu, Y., Qin, J., Chen, D., Wang, H., Wang, J. & Yu, Y., 2015, In : Cardiovascular Toxicology. 15, 2, p. 157-171 15 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Endothelial cells
Human Umbilical Vein Endothelial Cells
Electric network analysis
Chronic Disease
9 Citations (Scopus)

Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP

Cheng, T. H. T., Gorman, M., Martin, L., Barclay, E., Casey, G., Newcomb, P. A., Conti, D. V., Schumacher, F., Gallinger, S., Lindor, N. M., Hopper, J., Jenkins, M., Hunter, D. J., Kraft, P., Jacobs, K. B., Cox, D. G., Yeager, M., Hankinson, S. E., Wacholder, S., Wang, Z. & 148 others, Welch, R., Hutchinson, A., Wang, J., Yu, K., Chatterjee, N., Orr, N., Willett, W. C., Colditz, G. A., Ziegler, R. G., Berg, C. D., Buys, S. S., McCarty, C. A., Feigelson, H. S., Calle, E. E., Thun, M. J., Hayes, R. B., Tucker, M., Gerhard, D. S., Fraumeni, J. F., Hoover, R. N., Thomas, G., Chanock, S. J., Ciampa, J., Gonzalez-Bosquet, J., Berndt, S., Amundadottir, L., Diver, W. R., Albanes, D., Virtamo, J., Weinstein, S., Schumacher, F. R., Cancel-Tassin, G., Cussenot, O., Valeri, A., Andriole, G. L., Crawford, E. D., Haiman, C. A., Henderson, B., Kolonel, L., Marchand, L. L., Siddiq, A., Riboli, E., Key, T. J., Kaaks, R., Isaacs, W., Isaacs, S., Wiley, K. E., Gronberg, H., Wiklund, F., Stattin, P., Xu, J., Zheng, S. L., Sun, J., Vatten, L. J., Hveem, K., Kumle, M., Purdue, M. P., Johansson, M., Zelenika, D., Toro, J. R., Scelo, G., Moore, L. E., Prokhortchouk, E., Wu, X., Kiemeney, L. A., Gaborieau, V., Chow, W. H., Zaridze, D., Matveev, V., Lubinski, J., Trubicka, J., Szeszenia-Dabrowska, N., Lissowska, J., Rudnai, P., Fabianova, E., Bucur, A., Bencko, V., Foretova, L., Janout, V., Boffetta, P., Colt, J. S., Davis, F. G., Schwartz, K. L., Banks, R. E., Selby, P. J., Harnden, P., Hsing, A. W., Grubb, R. L., Boeing, H., Vineis, P., Clavel-Chapelon, F., Palli, D., Tumino, R., Krogh, V., Panico, S., Duell, E. J., Quirós, J. R., Sanchez, M. J., Navarro, C., Ardanaz, E., Dorronsoro, M., Khaw, K. T., Allen, N. E., Bueno-de-Mesquita, H. B., Peeters, P. H. M., Trichopoulos, D., Linseisen, J., Ljungberg, B., Overvad, K., Tjønneland, A., Romieu, I., Mukeria, A., Shangina, O., Stevens, V. L., Gapstur, S. M., Pharoah, P. D., Easton, D. F., Weinstein, S. J., Njølstad, I., Tell, G. S., Stoltenberg, C., Kumar, R., Koppova, K., Benhamou, S., Oosterwijk, E., Vermeulen, S. H., Aben, K. K. H., Van Der Marel, S. L., Ye, Y., Wood, C. G., Pu, X., Mazur, A. M., Boulygina, E. S., Chekanov, N. N., Foglio, M., Lechner, D., Gut, I., Heath, S., Blanche, H., Skryabin, K. G., McKay, J. D., Rothman, N., Lathrop, M., Brennan, P., Saunders, B., Thomas, H., Clark, S. & Tomlinson, I., Feb 20 2015, In : European Journal of Human Genetics. 23, 2, p. 260-263 4 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Adenoma
Colorectal Neoplasms
Alleles
Phenotype
8 Citations (Scopus)

Current trend of annotating single nucleotide variation in humans - A case study on SNVrap

Li, M. J. & Wang, J., Jun 1 2015, In : Methods. 79, p. 32-40 9 p.

Research output: Contribution to journalArticle

Nucleotides
Genes
Genome
Genomics
Exome
50 Citations (Scopus)

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: A report from the female lung cancer consortium in Asia

Machiela, M. J., Hsiung, C. A., Shu, X. O., Seow, W. J., Wang, Z., Matsuo, K., Hong, Y. C., Seow, A., Wu, C., Hosgood, H. D., Chen, K., Wang, J. C., Wen, W., Cawthon, R., Chatterjee, N., Hu, W., Caporaso, N. E., Park, J. Y., Chen, C. J., Kim, Y. H. & 112 others, Kim, Y. T., Landi, M. T., Shen, H., Lawrence, C., Burdett, L., Yeager, M., Chang, I. S., Mitsudomi, T., Kim, H. N., Chang, G. C., Bassig, B. A., Tucker, M., Wei, F., Yin, Z., An, S. J., Qian, B., Lee, V. H. F., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Kim, J. H., Gao, Y. T., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Hutchinson, A., Wang, W. C., Klein, R. J., Chung, C. C., Oh, I. J., Chen, K. Y., Berndt, S. I., Wu, W., Chang, J., Zhang, X. C., Huang, M. S., Zheng, H., Wang, J., Zhao, X., Li, Y., Choi, J. E., Su, W. C., Park, K. H., Sung, S. W., Chen, Y. M., Liu, L., Kang, C. H., Hu, L., Chen, C. H., Pao, W., Kim, Y. C., Yang, T. Y., Xu, J., Guan, P., Tan, W., Su, J., Wang, C. L., Li, H., Sihoe, A. D. L., Zhao, Z., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Cai, Q., Lin, C. C., Park, I. K., Xu, P., Dong, J., Kim, C., He, Q., Perng, R. P., Kohno, T., Kweon, S. S., Chen, C. Y., Vermeulen, R. C. H., Wu, J., Lim, W. Y., Chen, K. C., Chow, W. H., Ji, B. T., Chan, J. K. C., Chu, M., Li, Y. J., Yokota, J., Li, J., Chen, H., Xiang, Y. B., Yu, C. J., Kunitoh, H., Wu, G., Jin, L., Lo, Y. L., Shiraishi, K., Chen, Y. H., Lin, H. C., Wu, T., Wong, M. P., Wu, Y. L., Yang, P. C., Zhou, B., Shin, M. H., Fraumeni, J. F., Zheng, W., Lin, D., Chanock, S. J., Rothman, N. & Lan, Q., Jul 15 2015, In : International Journal of Cancer. 137, 2, p. 311-319 9 p.

Research output: Contribution to journalArticle

Telomere
Lung Neoplasms
Smoking
Genome-Wide Association Study
Women's Health
7 Citations (Scopus)

Human ocular epithelial cells endogenously expressing SOX2 and OCT4 yield high efficiency of pluripotency reprogramming

Poon, M. W., He, J., Fang, X., Zhang, Z., Wang, W., Wang, J., Qiu, F., Tse, H. F., Li, W., Liu, Z. & Lian, Q., Jul 1 2015, In : PLoS One. 10, 7, e0131288.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
stromal cells
epithelial cells
Stromal Cells
eyes
56 Citations (Scopus)

Potent Paracrine Effects of human induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells Attenuate Doxorubicin-induced Cardiomyopathy

Zhang, Y., Liang, X., Liao, S., Wang, W., Wang, J., Li, X., Ding, Y., Liang, Y., Gao, F., Yang, M., Fu, Q., Xu, A., Chai, Y. H., He, J., Tse, H. F. & Lian, Q., Jun 9 2015, In : Scientific Reports. 5, 11235.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Mesenchymal Stromal Cells
Cardiomyopathies
Doxorubicin
Growth Differentiation Factor 15
9 Citations (Scopus)

Proteomic profiling identifies the SIM-associated complex of KSHV-encoded LANA

Gan, J., Wang, C., Jin, Y., Guo, Y., Xu, F., Zhu, Q., Ding, L., Shang, H., Wang, J., Wei, F., Cai, Q. & Robertson, E. S., Jun 1 2015, In : Proteomics. 15, 12, p. 2023-2037 15 p.

Research output: Contribution to journalArticle

Human Herpesvirus 8
Proteomics
Sumoylation
Ubiquitin
Proteins
4 Citations (Scopus)

Rare SNP rs12731181 in the miR-590-3p target site of the prostaglandin F receptor gene confers risk for essential hypertension in the han Chinese population

Xiao, B., Gu, S. M., Li, M. J., Li, J., Tao, B., Wang, Y., Wang, Y., Zuo, S., Shen, Y., Yu, Y., Chen, D., Chen, G., Kong, D., Tang, J., Liu, Q., Chen, D. R., Liu, Y., Alberti, S., Dovizio, M., Landolfi, R. & 8 others, Mucci, L., Miao, P. Z., Gao, P., Zhu, D. L., Wang, J., Li, B., Patrignani, P. & Yu, Y., Jul 27 2015, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 7, p. 1687-1695 9 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Genotype
3' Untranslated Regions
Population
Genes
320 Citations (Scopus)

The support of human genetic evidence for approved drug indications

Nelson, M. R., Tipney, H., Painter, J. L., Shen, J., Nicoletti, P., Shen, Y., Floratos, A., Sham, P. C., Li, M. J., Wang, J., Cardon, L. R., Whittaker, J. C. & Sanseau, P., Aug 30 2015, In : Nature Genetics. 47, 8, p. 856-860 5 p.

Research output: Contribution to journalArticle

Medical Genetics
Pharmaceutical Preparations
Decision Making
Weights and Measures
Genes
5 Citations (Scopus)

wKGGSeq: A comprehensive strategy-based and disease-targeted online framework to facilitate exome sequencing studies of inherited disorders

Li, M. J., Deng, J., Wang, P., Yang, W., Ho, S. L., Sham, P. C., Wang, J. & Li, M., May 1 2015, In : Human Mutation. 36, 5, p. 496-503 8 p.

Research output: Contribution to journalArticle

Exome
Mutation
Genetic Research
Inborn Genetic Diseases
Psychiatry
2014
15 Citations (Scopus)

CMGRN: A web server for constructing multilevel gene regulatory networks using ChIP-seq and gene expression data

Guan, D., Shao, J., Deng, Y., Wang, P., Zhao, Z., Liang, Y., Wang, J. & Yan, B., 2014, In : Bioinformatics. 30, 8, p. 1190-1192 3 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Gene Regulatory Network
Web Server
Gene Expression Data
Gene expression
19 Citations (Scopus)

CTCF controls HOXA cluster silencing and mediates PRC2-repressive higher-order chromatin structure in NT2/D1 cells

Xu, M., Zhao, G. N., Lv, X., Liu, G., Wang, L. Y., Hao, D. L., Wang, J., Liu, D. P. & Liang, C. C., 2014, In : Molecular and Cellular Biology. 34, 20, p. 3867-3879 13 p.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 2
Chromatin
Multigene Family
Tretinoin
Histones