Projects per year
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Dive into the research topics where Jann N Sarkaria is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Quantitative systems biology of glioblastoma cells and their interactions with the neuronal and immunological milieu
Lauffenburger, D. A., Michor, F. F., Sarkaria, J. N. & Agar, N. Y. R.
9/15/23 → 8/31/24
Project: Research project
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Development of the brain penetrant ATM inhibitor WSD0628 in combination with radiation for recurrent high grade glioma
U.S. Food and Drug Administration
9/10/23 → 5/31/24
Project: Research project
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Endocytic Trafficking of ADCs in GBM cancer stem-like cells
Gladson, C. L. & Sarkaria, J. N.
National Institute of Neurological Disorders and Stroke
4/1/19 → 3/31/24
Project: Research project
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Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization
Chen, J., Laverty, D. J., Talele, S., Bale, A., Carlson, B. L., Porath, K. A., Bakken, K. K., Burgenske, D. M., Decker, P. A., Vaubel, R. A., Eckel-Passow, J. E., Bhargava, R., Lou, Z., Hamerlik, P., Harley, B., Elmquist, W. F., Nagel, Z. D., Gupta, S. K. & Sarkaria, J. N., 2024, In: Science translational medicine. 16, 734, eadj5962.Research output: Contribution to journal › Article › peer-review
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Delivery versus Potency in Treating Brain Tumors: BI-907828, a MDM2-p53 Antagonist with Limited BBB Penetration but Significant In Vivo Efficacy in Glioblastoma
Zhang, W., Vaubel, R. A., Oh, J. H., Mladek, A. C., Talele, S., Zhang, W., Waller, K. L., Burgenske, D. M., Sarkaria, J. N. & Elmquist, W. F., Jan 10 2024, In: Molecular cancer therapeutics. 23, 1, p. 47-55 9 p.Research output: Contribution to journal › Article › peer-review
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From the Operating Room to the Laboratory: Role of the Neuroscience Tissue Biorepository in the Clinical, Translational, and Basic Science Research Pipeline
Quiñones-Hinojosa, A., Basil, A., Moniz-Garcia, D., Suarez-Meade, P., Ramos, A., Jentoft, M., Middlebrooks, E., Grewal, S., Abode-Iyamah, K., Bydon, M., Sarkaria, J., Dickson, D., Swanson, K., Rosenfeld, S., Schiapparelli, P., Guerrero-Cazares, H., Chaichana, K. & Meyer, F., Feb 2024, In: Mayo Clinic proceedings. 99, 2, p. 229-240 12 p.Research output: Contribution to journal › Article › peer-review
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GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress
Zhou, W., Zhao, Z., Lin, A., Yang, J. Z., Xu, J., Wilder-Romans, K., Yang, A., Li, J., Solanki, S., Speth, J. M., Walker, N., Scott, A. J., Wang, L., Wen, B., Andren, A., Zhang, L., Kothari, A. U., Yao, Y., Peterson, E. R., Korimerla, N., & 20 others , Jan 1 2024, In: Cancer discovery. 14, 1, p. 158-175 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM
Petronek, M. S., Monga, V., Bodeker, K. L., Kwofie, M., Lee, C. Y., Mapuskar, K. A., Stolwijk, J. M., Zaher, A., Wagner, B. A., Smith, M. C., Vollstedt, S., Brown, H., Chandler, M. L., Lorack, A. C., Wulfekuhle, J. S., Sarkaria, J. N., Flynn, R. T., Greenlee, J. D. W., Howard, M. A., Smith, B. J., & 8 others , Jan 15 2024, In: Clinical Cancer Research. 30, 2, p. 283-293 11 p.Research output: Contribution to journal › Article › peer-review