Jann N Sarkaria, MD

Professor

  • 12044 Citations
  • 49 h-Index
1980 …2021
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  • 9 Similar Profiles
Glioblastoma Medicine & Life Sciences
temozolomide Medicine & Life Sciences
Heterografts Medicine & Life Sciences
Glioma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Brain Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Radiotherapy Medicine & Life Sciences

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Projects 1980 2021

Glioblastoma
Heterografts
Neoplasms
Organized Financing
Atlases
Natural Science Disciplines
Brain Neoplasms
Neoplasms
Pharmaceutical Preparations
Therapeutics
Double-Stranded DNA Breaks
Radiation
Skin
Fibroblasts
Radiation Tolerance
Glioblastoma
Disease-Free Survival
temozolomide
Heterografts
Exome

Research Output 1993 2019

  • 12044 Citations
  • 49 h-Index
  • 177 Article
  • 3 Review article

Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases

Gampa, G., Kim, M., Mohammad, A. S., Parrish, K. E., Mladek, A. C., Sarkaria, J. N. & Elmquist, W. F., Mar 1 2019, In : The Journal of pharmacology and experimental therapeutics. 368, 3, p. 446-461 16 p.

Research output: Contribution to journalArticle

Melanoma
Neoplasm Metastasis
P-Glycoprotein
Brain
Mitogen-Activated Protein Kinase Kinases

Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells

Nagel, Z. D., Beharry, A. A., Mazzucato, P., Kitange, G. J., Sarkaria, J. N., Kool, E. T. & Samson, L. D., Feb 1 2019, In : PloS one. 14, 2, e0208341.

Research output: Contribution to journalArticle

Open Access
methyltransferases
Methyltransferases
Assays
Cells
DNA

Methylation-dependent Tissue Factor Suppression Contributes to the Reduced Malignancy of IDH1-mutant Gliomas

Unruh, D., Mirkov, S., Wray, B., Drumm, M., Lamano, J., Li, Y. D., Haider, Q. F., Javier, R., McCortney, K., Saratsis, A., Scholtens, D. M., Sarkaria, J. N., David James, C. & Horbinski, C., Jan 15 2019, In : Clinical Cancer Research. 25, 2, p. 747-759 13 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Thromboplastin
Glioma
Methylation
Mutation

Quantifying the setup uncertainty of a stereotactic murine micro-image guided radiation therapy system

Walb, M. C., Carlson, B. L., Sarkaria, J. N. & Tryggestad, E. J., Mar 1 2019, In : The British journal of radiology. 92, 1095, 1 p.

Research output: Contribution to journalArticle

Image-Guided Radiotherapy
Cone-Beam Computed Tomography
Uncertainty
Nude Mice
Cranial Irradiation
4 Citations (Scopus)

A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma

Chen, X., Zhang, M., Gan, H., Wang, H., Lee, J. H., Fang, D., Kitange, G. J., He, L., Hu, Z., Parney, I. F., Meyer, F. B., Giannini, C., Sarkaria, J. N. & Zhang, Z., Dec 1 2018, In : Nature Communications. 9, 1, 2949.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Glioblastoma
deoxyribonucleic acid
DNA