• 5877 Citations
  • 40 Scopus h-Index
1993 …2020
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Research Output 1993 2019

  • 5877 Citations
  • 40 Scopus h-Index
  • 114 Article
  • 2 Chapter
  • 2 Comment/debate
  • 2 Review article
2019
3 Citations (Scopus)

EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis

Zhao, Y., Ding, L., Wang, D., Ye, Z., He, Y., Ma, L., Zhu, R., Pan, Y., Wu, Q., Pang, K., Hou, X., Weroha, S. J., Han, C., Coleman, R., Coleman, I., Karnes, R. J., Zhang, J., Nelson, P. S., Wang, L. & Huang, H., Jan 1 2019, In : EMBO Journal. e99599.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Growth
Protein Biosynthesis
Neoplasms
RNA Sequence Analysis
1 Citation (Scopus)

Lineage plasticity-mediated therapy resistance in prostate cancer

Blee, A. & Huang, H., May 1 2019, In : Asian Journal of Andrology. 21, 3, p. 241-248 8 p.

Research output: Contribution to journalReview article

Open Access
Prostatic Neoplasms
Androgen Receptors
Androgens
Therapeutics
Neoplasms

Overcoming EZH2 inhibitor resistance by taxane in PTEN-mutated cancer

Ma, L., Yan, Y., Bai, Y., Yang, Y., Pan, Y., Gang, X., Karnes, R. J., Zhang, J., Lv, Q., Wu, Q. & Huang, H., Jan 1 2019, In : Theranostics. 9, 17, p. 5020-5034 15 p.

Research output: Contribution to journalArticle

Open Access
docetaxel
Prostatic Neoplasms
Neoplasms
Polycomb-Group Proteins
Forkhead Transcription Factors
6 Citations (Scopus)

Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression

Jin, X., Ding, D., Yan, Y., Li, H., Wang, B., Ma, L., Ye, Z., Ma, T., Wu, Q., Rodrigues, D. N., Kohli, M., Jimenez, R. E., Wang, L., Goodrich, D. W., de Bono, J., Dong, H. M., Wu, H., Zhu, R. & Huang, H., Jan 3 2019, In : Molecular Cell. 73, 1, p. 22-35.e6

Research output: Contribution to journalArticle

Immunity
E2F Transcription Factors
Neoplasms
Phosphorylation

RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis

Bai, Y., Yang, Y., Yan, Y., Zhong, J., Blee, A. M., Pan, Y., Ma, T., Karnes, R. J., Jimenez, R. E., Xu, W. & Huang, H., Jan 1 2019, In : Theranostics. 9, 12, p. 3459-3475 17 p.

Research output: Contribution to journalArticle

Open Access
Haploinsufficiency
Prostate
Prostatic Neoplasms
Carcinogenesis
Phosphorylation
2018
11 Citations (Scopus)

Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer

He, Y., Lu, J., Ye, Z., Hao, S., Wang, L. M., Kohli, M., Tindall, D. J., Li, B., Zhu, R., Wang, L. & Huang, H., Feb 28 2018, In : Nucleic Acids Research. 46, 4, p. 1895-1911 17 p.

Research output: Contribution to journalArticle

Androgen Receptors
Castration
Chromatin
Prostatic Neoplasms
Growth
11 Citations (Scopus)

A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone

Wang, L., Dehm, S. M., Hillman, D. W., Sicotte, H., Tan, W., Gormley, M., Bhargava, V., Jimenez, R. E., Xie, F., Yin, P., Qin, S., Quevedo, F., Costello, B., Pitot, H. C., Ho, T. H., Bryce, A. H., Ye, Z., Li, Y., Eiken, P., Vedell, P. T. & 16 others, Barman, P., McMenomy, B. P., Atwell, T. D., Carlson, R. E., Ellingson, M., Eckloff, B. W., Qin, R., Ou, F., Hart, S., Huang, H., Jen, J., Wieben, E. D., Kalari, K. R., Weinshilboum, R. M., Wang, L. & Kohli, M., Feb 1 2018, In : Annals of Oncology. 29, 2, p. 352-360 9 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Prednisone
Prostatic Neoplasms
Cell Cycle
Cell Proliferation

Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing

Sheng, C., Yao, C., Wang, Z., Chen, H., Zhao, Y., Xu, D., Huang, H., Huang, W. & Chen, S., Dec 1 2018, In : Nature Communications. 9, 1, 4381.

Research output: Contribution to journalArticle

Cyclophilins
NF-kappa B
Ubiquitin
Zinc Fingers
Inflammation
8 Citations (Scopus)

Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in PTEN- or SPOP-mutated prostate cancer

Yan, Y., An, J., Yang, Y., Wu, D., Bai, Y., Cao, W., Ma, L., Chen, J., Yu, Z., He, Y., Jin, X., Pan, Y., Ma, T., Wang, S., Hou, X., Weroha, S. J., Karnes, R. J., Zhang, J., Westendorf, J. J., Wang, L. & 5 others, Chen, Y., Xu, W., Zhu, R., Wang, D. & Huang, H., Jan 1 2018, (Accepted/In press) In : EMBO Molecular Medicine.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Phosphorylation
Lysine
Organoids
14 Citations (Scopus)

DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4

Jin, X., Yan, Y., Wang, D., Ding, D., Ma, T., Ye, Z., Jimenez, R. E., Wang, L., Wu, H. & Huang, H., Aug 16 2018, In : Molecular Cell. 71, 4, p. 592-605.e4

Research output: Contribution to journalArticle

Neoplasms
Prostatic Neoplasms
Proteins
Castration
Drug Resistance
9 Citations (Scopus)

LSD1 promotes S-phase entry and tumorigenesis via chromatin co-occupation with E2F1 and selective H3K9 demethylation

He, Y., Zhao, Y., Wang, L., Bohrer, L. R., Pan, Y., Wang, L. & Huang, H., Jan 25 2018, In : Oncogene. 37, 4, p. 534-543 10 p.

Research output: Contribution to journalArticle

S Phase
Occupations
Lysine
Chromatin
Carcinogenesis
4 Citations (Scopus)

Prevalent homozygous deletions of type i interferon and defensin genes in human cancers associate with immunotherapy resistance

Ye, Z., Dong, H. M., Li, Y., Ma, T., Huang, H., Leong, H. S., Eckel-Passow, J. E., Kocher, J-P., Liang, H. & Wang, L., Jul 15 2018, In : Clinical Cancer Research. 24, 14, p. 3299-3308 10 p.

Research output: Contribution to journalArticle

Defensins
Immunotherapy
Interferons
Genes
Neoplasms
10 Citations (Scopus)

PTEN loss promotes intratumoral androgen synthesis and tumor microenvironment remodeling via aberrant activation of RUNX2 in castration-Resistant prostate cancer

Yang, Y., Bai, Y., He, Y., Zhao, Y., Chen, J., Ma, L., Pan, Y., Hinten, M., Zhang, J., Karnes, R. J., Kohli, M., Westendorf, J. J., Li, B., Zhu, R., Huang, H. & Xu, W., Feb 15 2018, In : Clinical Cancer Research. 24, 4, p. 834-846 13 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Castration
Androgens
Testosterone
Prostatic Neoplasms
7 Citations (Scopus)

TMPrSS2-ERG controls luminal epithelial lineage and antiandrogen sensitivity in PTEN and TP53-mutated prostate cancer

Blee, A. M., He, Y., Yang, Y., Ye, Z., Yan, Y., Pan, Y., Ma, T., Dugdale, J., Kuehn, E., Kohli, M., Jimenez, R. E., Chen, Y., Xu, W., Wang, L. & Huang, H., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4551-4565 15 p.

Research output: Contribution to journalArticle

Androgen Antagonists
Prostatic Neoplasms
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase 4
Neoplasms
2017
21 Citations (Scopus)

AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction

Pan, C. W., Jin, X., Zhao, Y., Pan, Y., Yang, J., Karnes, R. J., Zhang, J., Wang, L. & Huang, H., 2017, (Accepted/In press) In : EMBO Journal.

Research output: Contribution to journalArticle

Phosphorylation
Chemical activation
Cells
Neoplasms
Tumors
29 Citations (Scopus)

Androgen receptor variant AR-V9 is coexpressed with AR-V7 in prostate cancer metastases and predicts abiraterone resistance

Kohli, M., Ho, Y., Hillman, D. W., Van Etten, J. L., Henzler, C., Yang, R., Sperger, J. M., Li, Y., Tseng, E., Hon, T., Clark, T., Tan, W., Carlson, R. E., Wang, L., Sicotte, H., Ho, T. H., Jimenez, R. E., Huang, H., Vedell, P. T., Eckloff, B. W. & 9 others, Quevedo, J. F., Pitot, H. C., Costello, B., Jen, J., Wieben, E. D., Silverstein, K. A. T., Lang, J. M., Wang, L. M. & Dehm, S. M., Aug 15 2017, In : Clinical Cancer Research. 23, 16, p. 4704-4715 12 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Neoplasm Metastasis
Castration
abiraterone

Correction: A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands [Oncotarget, 7, (2016) (86087-86102)] DOI:10.18632/oncotarget.13343

Qin, T., Barron, L., Xia, L., Huang, H., Villarreal, M. M., Zwaagstra, J., Collins, C., Yang, J., Zwieb, C., Kodali, R., Hinck, C. S., Kim, S. K., Reddick, R. L., Shu, C., O'Connor-McCourt, M. D., Hinck, A. P. & Sun, L. Z., Jan 1 2017, In : Oncotarget. 8, 34, 1 p.

Research output: Contribution to journalComment/debate

Transforming Growth Factor beta Receptors
Prostate
Carcinogenesis
Neoplasms
14 Citations (Scopus)

Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer

Jin, X., Wang, J., Gao, K., Zhang, P., Yao, L., Tang, Y., Tang, L., Ma, J., Xiao, J., Zhang, E., Zhu, J., Zhang, B., Zhao, S. M., Li, Y., Ren, S., Huang, H., Yu, L. & Wang, C., Apr 1 2017, In : PLoS Genetics. 13, 4, e1006748.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
speckle
prostatic neoplasms
cancer
Prostatic Neoplasms
24 Citations (Scopus)

Fructose-1,6-bisphosphatase inhibits ERK activation and bypasses gemcitabine resistance in pancreatic cancer by blocking IQGAP1–MAPK interaction

Jin, X., Pan, Y., Wang, L., Ma, T., Zhang, L., Tang, A. H., Billadeau, D. D., Wu, H. & Huang, H., Aug 15 2017, In : Cancer Research. 77, 16, p. 4328-4341 14 p.

Research output: Contribution to journalArticle

gemcitabine
Fructose-Bisphosphatase
Pancreatic Neoplasms
Adenocarcinoma
Gluconeogenesis
19 Citations (Scopus)

Inhibiting histone deacetylases suppresses glucose metabolism and hepatocellular carcinoma growth by restoring FBP1 expression

Yang, J., Jin, X., Yan, Y., Shao, Y., Pan, Y., Roberts, L. R., Zhang, J., Huang, H. & Jiang, J., Mar 6 2017, In : Scientific Reports. 7, 43864.

Research output: Contribution to journalArticle

Histone Deacetylases
Hepatocellular Carcinoma
Glucose
Growth
Histone Deacetylase 1
49 Citations (Scopus)

Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation

Zhang, P., Wang, D., Zhao, Y., Ren, S., Gao, K., Ye, Z., Wang, S., Pan, C. W., Zhu, Y., Yan, Y., Yang, Y., Wu, D., He, Y., Zhang, J., Lu, D., Liu, X., Yu, L., Zhao, S., Li, Y., Lin, D. & 6 others, Wang, Y., Wang, L., Chen, Y., Sun, Y., Wang, C. & Huang, H., Sep 1 2017, In : Nature Medicine. 23, 9, p. 1055-1062 8 p.

Research output: Contribution to journalArticle

Speckle
Prostatic Neoplasms
Stabilization
Chemical activation
Mutant Proteins
15 Citations (Scopus)

Loss of FOXO1 cooperates with TMPRSS2–ERG overexpression to promote prostate tumorigenesis and cell invasion

Yang, Y., Blee, A. M., Wang, D., An, J., Pan, Y., Yan, Y., Ma, T., He, Y., Dugdale, J., Hou, X., Zhang, J., Weroha, S. J., Zhu, W. G., Wang, Y. A., DePinho, R. A., Xu, W. & Huang, H., Dec 1 2017, In : Cancer Research. 77, 23, p. 6524-6537 14 p.

Research output: Contribution to journalArticle

Prostate
Prostatic Neoplasms
Carcinogenesis
Transgenes
Prostatic Intraepithelial Neoplasia
22 Citations (Scopus)

MAGE-TRIM28 complex promotes the Warburg effect and hepatocellular carcinoma progression by targeting FBP1 for degradation

Jin, X., Pan, Y., Wang, L., Zhang, L., Ravichandran, R., Potts, P. R., Jiang, J., Wu, H. & Huang, H., Jan 1 2017, In : Oncogenesis. 6, 4, e312.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasms
Fructose-Bisphosphatase
Tripartite Motif Proteins
Proteasome Inhibitors
7 Citations (Scopus)

Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway: This article has been corrected since Advance Online Publication and a corrigendum is also printed in this issue

Ding, D., Huang, H., Jiang, W., Yu, W., Zhu, H., Liu, J., Saiyin, H., Wu, J., Huang, H., Jiang, S. & Yu, L., Nov 30 2017, In : Oncogene. 36, 48, p. 6691-6700 10 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Epidermal Growth Factor Receptor
Publications
Hepatocellular Carcinoma
Cell Proliferation
23 Citations (Scopus)

Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression

Ren, S., Wei, G. H., Liu, D., Wang, L., Hou, Y., Zhu, S., Peng, L., Zhang, Q., Cheng, Y., Su, H., Zhou, X., Zhang, J., Li, F., Zheng, H., Zhao, Z., Yin, C., He, Z., Gao, X., Zhau, H. E., Chu, C. Y. & 42 others, Wu, J. B., Collins, C., Volik, S. V., Bell, R., Huang, J., Wu, K., Xu, D., Ye, D., Yu, Y., Zhu, L., Qiao, M., Lee, H. M., Yang, Y., Zhu, Y., Shi, X., Chen, R., Wang, Y., Xu, W., Cheng, Y., Xu, C., Gao, X., Zhou, T., Yang, B., Hou, J., Liu, L., Zhang, Z., Zhu, Y., Qin, C., Shao, P., Pang, J., Chung, L. W. K., Xu, J., Wu, C. L., Zhong, W., Xu, X., Li, Y., Zhang, X., Wang, J., Yang, H., Wang, J., Huang, H. & Sun, Y., Jan 1 2017, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Transcriptome
Disease Progression
Prostatic Neoplasms
Genome
Prostate
2016
26 Citations (Scopus)

Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer

Zhao, Y., Wang, L., Ren, S., Wang, L., Blackburn, P. R., McNulty, M. S., Gao, X., Qiao, M., Vessella, R. L., Kohli, M., Zhang, J., Karnes, R. J., Tindall, D. J., Kim, Y., MacLeod, R., Ekker, S. C., Kang, T., Sun, Y. & Huang, H., Apr 19 2016, In : Cell Reports. 15, 3, p. 599-610 12 p.

Research output: Contribution to journalArticle

Positive Transcriptional Elongation Factor B
Castration
Androgen Receptors
Prostatic Neoplasms
Chemical activation
9 Citations (Scopus)

A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A

Wu, Y., Zhou, L., Wang, X., Lu, J., Zhang, R., Liang, X., Wang, L., Deng, W., Zeng, Y. X., Huang, H. & Kang, T., May 24 2016, In : Cell Discovery. 2, 16014.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Protein Stability
Screening
Genes
Genome
12 Citations (Scopus)

Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castrationresistant prostate cancer

Zhao, J., Zhao, Y., Wang, L., Zhang, J., Karnes, R. J., Kohli, M., Wang, G. & Huang, H., 2016, In : Oncotarget. 7, 25, p. 38551-38565 15 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
RNA
Meta-Analysis
Growth

Androgen receptor signaling in castration resistant prostate cancer

Zhao, Y., Tindall, D. J. & Huang, H., Jan 1 2016, Managing Metastatic Prostate Cancer In Your Urological Oncology Practice. Springer International Publishing, p. 23-34 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Castration
Androgen Receptors
Prostatic Neoplasms
6 Citations (Scopus)

A novel highly potent trivalent TGF-ß receptor trap inhibits earlystage tumorigenesis and tumor cell invasion in murine ptendeficient prostate glands

Qin, T., Barron, L., Xia, L., Huang, H., Villarreal, M. M., Zwaagstra, J., Collins, C., Yang, J., Zwieb, C., Kodali, R., Hinck, C. S., Kim, S. K., Reddick, R. L., Shu, C., O'Connor-McCourt, M. D., Hinck, A. P. & Sun, L. Z., 2016, In : Oncotarget. 7, 52, p. 86087-86102 16 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta Receptors
Transforming Growth Factor beta
Prostate
Carcinogenesis
Neoplasms
20 Citations (Scopus)

BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion

Blee, A. M., Liu, S., Wang, L. & Huang, H., 2016, In : Oncotarget. 7, 25, p. 38319-38332 14 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Castration
Exons
Hormones
Chromatin Immunoprecipitation
2 Citations (Scopus)

Fat lure: Adipocytes attract cancer cells out of the prostate

Blee, A. M. & Huang, H., 2016, In : Translational Cancer Research. 5, p. S123-S125

Research output: Contribution to journalComment/debate

Adipocytes
Prostate
Fats
Neoplasms
15 Citations (Scopus)

Inhibition of EZH2 by chemo- and radiotherapy agents and small molecule inhibitors induces cell death in castration-resistant prostate cancer

Wu, C., Jin, X., Yang, J., Yang, Y., He, Y., Ding, L., Pan, Y., Chen, S., Jiang, J. & Huang, H., 2016, In : Oncotarget. 7, 3, p. 3440-3452 13 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Cell Death
Radiotherapy
Drug Therapy
25 Citations (Scopus)

Isorhapontigenin (ISO) inhibits invasive bladder cancer formation In Vivo and human bladder cancer invasion In Vitro by targeting STAT1/FOXO1 axis

Jiang, G., Wu, A. D., Huang, C., Gu, J., Zhang, L., Huang, H., Liao, X., Li, J., Zhang, D., Zeng, X., Jin, H., Huang, H. & Huang, C., Jul 1 2016, In : Cancer Prevention Research. 9, 7, p. 567-580 14 p.

Research output: Contribution to journalArticle

STAT1 Transcription Factor
Urinary Bladder Neoplasms
isorhapontigenin
In Vitro Techniques
Gnetum
15 Citations (Scopus)

KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway

Li, L., Duan, T., Wang, X., Zhang, R. H., Zhang, M., Wang, S., Wang, F., Wu, Y., Huang, H. & Kang, T., Feb 5 2016, In : Scientific Reports. 6, 20460.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Colorectal Neoplasms
Neoplastic Stem Cells
Xenograft Model Antitumor Assays
Potassium Channels
35 Citations (Scopus)

Measure transcript integrity using RNA-seq data

Wang, L., Nie, J., Sicotte, H., Li, Y., Eckel-Passow, J. E., Dasari, S., Vedell, P. T., Barman, P., Wang, L. M., Weinshiboum, R., Jen, J., Huang, H., Kohli, M. & Kocher, J-P., Feb 3 2016, In : BMC Bioinformatics. 17, 1

Research output: Contribution to journalArticle

RNA
Integrity
RNA Stability
Degradation
Gene expression
23 Citations (Scopus)

P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth

Gang, X., Yang, Y., Zhong, J., Jiang, K., Pan, Y., Karnes, R. J., Zhang, J., Xu, W., Wang, G. & Huang, H., Mar 22 2016, In : Oncotarget. 7, 12, p. 15135-15149 15 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Lipid Metabolism
Prostatic Neoplasms
Growth
Fatty Acids

PMEPA1 guards against TGF-β-mediated prostate cancer bone metastasis

Blee, A. M. & Huang, H., 2016, In : Asian Journal of Urology. 3, 1, p. 1-3 3 p.

Research output: Contribution to journalReview article

Bone Neoplasms
Transforming Growth Factor beta
Prostatic Neoplasms
Neoplasm Metastasis
7 Citations (Scopus)

RNF12 promotes p53-dependent cell growth suppression and apoptosis by targeting MDM2 for destruction

Gao, K., Wang, C., Jin, X., Xiao, J., Zhang, E., Yang, X., Wang, D., Huang, H., Yu, L. & Zhang, P., May 28 2016, In : Cancer Letters. 375, 1, p. 133-141 9 p.

Research output: Contribution to journalArticle

Ubiquitination
Ubiquitin-Protein Ligases
Apoptosis
Growth
Neoplasms
8 Citations (Scopus)

Zinc finger protein 191 inhibits hepatocellular carcinoma metastasis through discs large 1-mediated yes-associated protein inactivation

Wu, D., Liu, G., Liu, Y., Saiyin, H., Wang, C., Wei, Z., Zen, W., Liu, D., Chen, Q., Zhao, Z., Zou, L., Huang, H., Jiang, S. & Yu, L., 2016, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Zinc Fingers
Hepatocellular Carcinoma
Neoplasm Metastasis
Proteins
Cell Movement
2015
9 Citations (Scopus)

Androgens regulate SMAD ubiquitination regulatory factor-1 expression and prostate cancer cell invasion

Gang, X., Wang, G. & Huang, H., May 1 2015, In : Prostate. 75, 6, p. 561-572 12 p.

Research output: Contribution to journalArticle

Ubiquitination
Androgens
Prostatic Neoplasms
Androgen Receptors
Neoplasm Metastasis
5 Citations (Scopus)

ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments

Zhang, P., Zhang, Y., Gao, K., Wang, Y., Jin, X., Wei, Y., Saiyin, H., Wang, D., Peng, J., Ma, J., Tang, Y., Wumaier, R., Yu, H., Dong, Y., Huang, H., Yu, L. & Wang, C., Dec 8 2015, In : Oncotarget. 6, 39, p. 41550-41565 16 p.

Research output: Contribution to journalArticle

Kinetochores
Chromosome Segregation
Microtubules
Chromosomes
M Phase Cell Cycle Checkpoints
5 Citations (Scopus)

Detecting the H3F3A mutant allele found in high-grade pediatric glioma by real-time PCR

Zhang, R., Han, J., Daniels, D., Huang, H. & Zhang, Z., Sep 16 2015, (Accepted/In press) In : Journal of Neuro-Oncology.

Research output: Contribution to journalArticle

Glioma
Real-Time Polymerase Chain Reaction
Alleles
Pediatrics
Mutation
18 Citations (Scopus)

Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover

Zhang, P., Gao, K., Jin, X., Ma, J., Peng, J., Wumaier, R., Tang, Y., Zhang, Y., An, J., Yan, Q., Dong, Y., Huang, H., Yu, L. & Wang, C., 2015, In : Cell death & disease. 6, p. e1687

Research output: Contribution to journalArticle

Endometrial Neoplasms
Estrogen Receptors
Proteins
Ubiquitin-Protein Ligases
Ubiquitination
3 Citations (Scopus)

Epidaurus: Aggregation and integration analysis of prostate cancer epigenome

Wang, L., Huang, H., Dougherty, G., Zhao, Y., Hossain, A. & Kocher, J-P., Jan 30 2015, In : Nucleic Acids Research. 43, 2, p. e7

Research output: Contribution to journalArticle

Epigenomics
Prostatic Neoplasms
Androgen Receptors
Cell Line
Neoplasm Genes
94 Citations (Scopus)

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castrationresistant prostate cancer

Wang, D., Ding, L., Wang, L., Zhao, Y., Sun, Z. D., Karnes, R. J., Zhang, J. & Huang, H., 2015, In : Oncotarget. 6, 38, p. 41045-41055 11 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Castration
Enhancer of Zeste Homolog 2 Protein
Long Noncoding RNA
RNA
27 Citations (Scopus)

Regulation of cell cycle of hepatocellular carcinoma by NF90 through modulation of cyclin E1 mRNA stability

Jiang, W., Huang, H., Ding, L., Zhu, P., Saiyin, H., Ji, G., Zuo, J., Han, D., Pan, Y., Ding, D., Ma, X., Zhang, Y., Wu, J., Yi, Q., Liu, J. O., Huang, H., Dang, Y. & Yu, L., Aug 20 2015, In : Oncogene. 34, 34, p. 4460-4470 11 p.

Research output: Contribution to journalArticle

Nuclear Factor 90 Proteins
Cyclins
RNA Stability
Hepatocellular Carcinoma
Cell Cycle
29 Citations (Scopus)

The cistrome and gene signature of androgen receptor splice variants in castration resistant prostate cancer cells

Lu, J., Lonergan, P. E., Nacusi, L. P., Wang, L., Schmidt, L. J., Sun, Z. D., Van Der Steen, T., Boorjian, S. A., Kosari, F., Vasmatzis, G., Klee, G. G., Balk, S. P., Huang, H., Wang, C. & Tindall, D. J., Feb 1 2015, In : Journal of Urology. 193, 2, p. 690-698 9 p.

Research output: Contribution to journalArticle

Castration
Androgen Receptors
Prostatic Neoplasms
Genes
Androgens
56 Citations (Scopus)

Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation

An, J., Ren, S., Murphy, S. J., Dalangood, S., Chang, C., Pang, X., Cui, Y., Wang, L., Pan, Y., Zhang, X., Zhu, Y., Wang, C., Halling, G. C., Cheng, L., Sukov, W. R., Karnes, R. J., Vasmatzis, G., Zhang, Q., Zhang, J., Cheville, J. C. & 3 others, Yan, J., Sun, Y. & Huang, H., Sep 17 2015, In : Molecular Cell. 59, 6, p. 904-916 13 p.

Research output: Contribution to journalArticle

Oncogene Proteins
Proteasome Endopeptidase Complex
Prostatic Neoplasms
Mutation
Ubiquitin-Protein Ligases
2014
21 Citations (Scopus)

CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: Implications for epigenetic therapy

Ding, L., Chen, S., Liu, P., Pan, Y., Zhong, J., Regan, K. M., Wang, L., Yu, C., Rizzardi, A., Cheng, L., Zhang, J., Schmechel, S. C., Cheville, J. C., Van Deursen, J., Tindall, D. J. & Huang, H., Apr 1 2014, In : Cancer Research. 74, 7, p. 2050-2061 12 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Epigenomics
Prostatic Neoplasms
Histones
Prostate