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Haojie Huang, PhD

Professor

  • 5300 Citations
  • 39 h-Index
1993 …2020
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  • 2 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Androgens Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Castration Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Prostate Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences

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Projects 2008 2020

Role of RUNX2 in prostate cancer intratumoral androgen synthesis and progression

Huang, H.

National Institutes of Health

9/25/15 → 8/31/20

Project: Research project › Research Project

Androgens
Prostatic Neoplasms
Castration
Prostate
Neoplasms

FOXO1 Inhibition in Genotoxic Stress Response and Prostate Cancer Survival

Huang, H.

National Institutes of Health

7/1/08 → 6/30/20

Project: Research project › Research Project

Prostatic Neoplasms
DNA Damage
Prostate
Carcinogenesis
Phosphorylation

Mechanism and role of aberrant AR activity in castration-resistant prostate cancer

Huang, H.

Project: Research project

Mechanism of promiscuous AR activation in PTEN-mutated prostate cancer

Huang, H.

National Institutes of Health

6/1/10 → 5/31/16

Project: Research project › Research Project

Androgen Receptors
Prostatic Neoplasms
Androgens
Castration
Interleukin-6

Research Output 1993 2018

  • 5300 Citations
  • 39 h-Index
  • 110 Article
  • 2 Chapter
  • 2 Comment/debate
  • 1 Review article
5 Citations

Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer

He, Y., Lu, J., Ye, Z., Hao, S., Wang, L. M., Kohli, M., Tindall, D. J., Li, B., Zhu, R., Wang, L. & Huang, H., Feb 28 2018, In : Nucleic Acids Research. 46, 4, p. 1895-1911 17 p.

Research output: Contribution to journal › Article

Androgen Receptors
Castration
Chromatin
Prostatic Neoplasms
Growth
5 Citations

A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone

Wang, L., Dehm, S. M., Hillman, D. W., Sicotte, H., Tan, W., Gormley, M., Bhargava, V., Jimenez, R. E., Xie, F., Yin, P., Qin, S., Quevedo, F., Costello, B., Pitot, H. C., Ho, T. H., Bryce, A. H., Ye, Z., Li, Y., Eiken, P., Vedell, P. T. & 16 othersBarman, P., McMenomy, B. P., Atwell, T. D., Carlson, R. E., Ellingson, M., Eckloff, B. W., Qin, R., Ou, F., Hart, S., Huang, H., Jen, J., Wieben, E. D., Kalari, K. R., Weinshilboum, R. M., Wang, L. & Kohli, M., Feb 1 2018, In : Annals of Oncology. 29, 2, p. 352-360 9 p.

Research output: Contribution to journal › Article

Wnt Signaling Pathway
Prednisone
Prostatic Neoplasms
Cell Cycle
Cell Proliferation

Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing

Sheng, C., Yao, C., Wang, Z., Chen, H., Zhao, Y., Xu, D., Huang, H., Huang, W. & Chen, S., Dec 1 2018, In : Nature communications. 9, 1, 4381.

Research output: Contribution to journal › Article

Cyclophilins
Ubiquitin
homeostasis
Zinc Fingers
Inflammation
1 Citations

Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in PTEN- or SPOP-mutated prostate cancer

Yan, Y., An, J., Yang, Y., Wu, D., Bai, Y., Cao, W., Ma, L., Chen, J., Yu, Z., He, Y., Jin, X., Pan, Y., Ma, T., Wang, S., Hou, X., Weroha, S. J., Karnes, R. J., Zhang, J., Westendorf, J. J., Wang, L. & 5 othersChen, Y., Xu, W., Zhu, R., Wang, D. & Huang, H., Jan 1 2018, (Accepted/In press) In : EMBO Molecular Medicine.

Research output: Contribution to journal › Article

Androgen Receptors
Prostatic Neoplasms
Phosphorylation
Lysine
Organoids
2 Citations

DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4

Jin, X., Yan, Y., Wang, D., Ding, D., Ma, T., Ye, Z., Jimenez, R. E., Wang, L., Wu, H. & Huang, H., Aug 16 2018, In : Molecular Cell. 71, 4, p. 592-605.e4

Research output: Contribution to journal › Article

Neoplasms
Prostatic Neoplasms
Proteins
Castration
Drug Resistance