Fabienne Fiesel, PhD

  • 5098 Citations
  • 24 Scopus h-Index
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  • 16 Similar Profiles
Parkinson Disease Medicine & Life Sciences
Mitochondrial Degradation Medicine & Life Sciences
Mitochondria Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Mutation Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Autophagy Medicine & Life Sciences

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Research Output 2008 2019

3 Citations (Scopus)

The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

Lee, S. B., Kim, J. J., Han, S. A., Fan, Y., Guo, L. S., Aziz, K., Nowsheen, S., Kim, S. S., Park, S. Y., Luo, Q., Chung, J. O., Choi, S. I., Aziz, A., Yin, P., Tong, S. Y., Fiesel, F., Springer, W., Zhang, J. S. & Lou, Z., Aug 1 2019, In : Nature Cell Biology. 21, 8, p. 940-951 12 p.

Research output: Contribution to journalArticle

Receptor-Interacting Protein Serine-Threonine Kinases
AMP-Activated Protein Kinases
Ubiquitin-Protein Ligases
6 Citations (Scopus)

Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease

Hou, X., Fiesel, F., Truban, D., Castanedes Casey, M., Lin, W. L., Soto, A. I., Tacik, P., Rousseau, L. G., Diehl, N. N., Heckman, M. G., Lorenzo-Betancor, O., Ferrer, I., Arbelo, J. M., Steele, J. C., Farrer, M. J., Cornejo-Olivas, M., Torres, L., Mata, I. F., Graff Radford, N. R., Wszolek, Z. K. & 4 others, Ross, O. A., Murray, M. E., Dickson, D. W. & Springer, W., Jan 1 2018, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Lewy Body Disease
Parkinson Disease
Carbonyl Cyanide m-Chlorophenyl Hydrazone
45 Citations (Scopus)

Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism

Puschmann, A., Fiesel, F., Caulfield, T., Hudec, R., Ando, M., Truban, D., Hou, X., Ogaki, K., Heckman, M. G., James, E. D., Swanberg, M., Jimenez-Ferrer, I., Hansson, O., Opala, G., Siuda, J., Boczarska-Jedynak, M., Friedman, A., Koziorowski, D., Aasly, J. O., Lynch, T. & 12 others, Mellick, G. D., Mohan, M., Silburn, P. A., Sanotsky, Y., Vilariño-Güell, C., Farrer, M. J., Chen, L., Dawson, V. L., Dawson, T. M., Wszolek, Z. K., Wszolek, Z. K. & Ross, O. A., Jan 1 2017, In : Brain : a journal of neurology. 140, p. 98-117 20 p.

Research output: Contribution to journalArticle

Parkinson Disease
Odds Ratio
PTEN-induced putative kinase
10 Citations (Scopus)

Hexokinases link DJ-1 to the PINK1/parkin pathway

Hauser, D. N., Mamais, A., Conti, M. M., Primiani, C. T., Kumaran, R., Dillman, A. A., Langston, R. G., Beilina, A., Garcia, J. H., Diaz-Ruiz, A., Bernier, M., Fiesel, F., Hou, X., Springer, W., Li, Y., De Cabo, R. & Cookson, M. R., Sep 29 2017, In : Molecular Neurodegeneration. 12, 1, 212.

Research output: Contribution to journalArticle

Parkinson Disease
PTEN Phosphohydrolase
8 Citations (Scopus)

Mitochondrial targeted HSP90 inhibitor Gamitrinib-TPP (G-TPP) induces PINK1/Parkin-dependent mitophagy

Fiesel, F., James, E. D., Hudec, R. & Springer, W., Jan 1 2017, In : Oncotarget. 8, 63, p. 106233-106248 16 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Mitochondrial Proteins