• 6060 Citations
  • 39 Scopus h-Index
1980 …2019
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Fingerprint Dive into the research topics where Edward B Leof is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Transforming Growth Factors Medicine & Life Sciences
Growth Factor Receptors Medicine & Life Sciences
Pneumocystis carinii Medicine & Life Sciences
Fibroblasts Medicine & Life Sciences
Epidermal Growth Factor Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
BALB 3T3 Cells Medicine & Life Sciences
Platelet-Derived Growth Factor Medicine & Life Sciences

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Projects 1986 2019

Symposium on Extracellular and Membrane Proteases in Cell Signaling

Blobel, G., Overall, C. M., Matrisian, L., Trejo, J., Hung, M., Nilsen-Hamilton, M. & Leof, E. B.

National Institutes of Health

9/4/088/31/09

Project: Research project

Peptide Hydrolases
Membranes
Posters
Meals
Atmosphere
Transforming Growth Factor beta Receptors
Transforming Growth Factor beta
Epithelial Cells
Growth
Sorting Nexins
Transforming Growth Factor beta Receptors
Transforming Growth Factor beta
Cell Proliferation
p21-Activated Kinases
Growth
Transforming Growth Factor beta
Transforming Growth Factor beta1
Gene Expression
Agar
Growth
Proto-Oncogenes
Transforming Growth Factor beta1
Cell Proliferation
GTP-Binding Proteins
myc Genes

Research Output 1980 2019

  • 6060 Citations
  • 39 Scopus h-Index
  • 106 Article

B7-1 drives TGF-β stimulated pancreatic carcinoma cell migration and expression of EMT target genes

Kang, J. H., Jung, M. Y. & Leof, E. B., Jan 1 2019, In : PloS one. 14, 9, e0222083.

Research output: Contribution to journalArticle

Open Access
Epithelial-Mesenchymal Transition
transforming growth factor beta
cell movement
Transforming Growth Factor beta
carcinoma
6 Citations (Scopus)

Fatty acid synthase is required for profibrotic TGF-b signaling

Jung, M. Y., Kang, J. H., Hernandez, D. M., Yin, X., Andrianifahanana, M., Wang, Y., Gonzalez-Guerrico, A., Limper, A. H., Lupu, R. & Leof, E. B., Jul 1 2018, In : FASEB Journal. 32, 7, p. 3803-3815 13 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Lung
Oxygenation
Pulmonary Fibrosis
Toxicity
5 Citations (Scopus)

Basolateral delivery of the type i transforming growth factor beta receptor is mediated by a dominant-acting cytoplasmic motif

Yin, X., Kang, J. H., Andrianifahanana, M., Wang, Y., Jung, M. Y., Hernandez, D. M. & Leof, E. B., Oct 1 2017, In : Molecular Biology of the Cell. 28, 20, p. 2701-2711 11 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta Receptors
Epithelium
Nerve Growth Factor Receptor
Recycling
Point Mutation
13 Citations (Scopus)

Cell-penetrating peptides selectively targeting SMAD3 inhibit profibrotic TGF-β signaling

Kang, J. H., Jung, M. Y., Yin, X., Andrianifahanana, M., Hernandez, D. M. & Leof, E. B., Jun 30 2017, In : Journal of Clinical Investigation. 127, 7, p. 2541-2554 14 p.

Research output: Contribution to journalArticle

Sorting Nexins
Cell-Penetrating Peptides
Peptides
Bone Morphogenetic Protein 4
Human Immunodeficiency Virus Proteins
3 Citations (Scopus)

CorMatrix Wrapped Around the Adventitia of the Arteriovenous Fistula Outflow Vein Attenuates Venous Neointimal Hyperplasia

Yang, B., Kilari, S., Brahmbhatt, A., McCall, D. L., Torres, E. N., Leof, E. B., Mukhopadhyay, D. & Misra, S., Dec 1 2017, In : Scientific Reports. 7, 1, 14298.

Research output: Contribution to journalArticle

Adventitia
Arteriovenous Fistula
Hyperplasia
Veins
Neointima