• 6101 Citations
  • 39 Scopus h-Index
1980 …2019
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Research Output 1980 2019

  • 6101 Citations
  • 39 Scopus h-Index
  • 106 Article
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Article
2019

B7-1 drives TGF-β stimulated pancreatic carcinoma cell migration and expression of EMT target genes

Kang, J. H., Jung, M. Y. & Leof, E. B., Jan 1 2019, In : PloS one. 14, 9, e0222083.

Research output: Contribution to journalArticle

Open Access
Epithelial-Mesenchymal Transition
transforming growth factor beta
cell movement
Transforming Growth Factor beta
carcinoma
2018
8 Citations (Scopus)

Fatty acid synthase is required for profibrotic TGF-b signaling

Jung, M. Y., Kang, J. H., Hernandez, D. M., Yin, X., Andrianifahanana, M., Wang, Y., Gonzalez-Guerrico, A., Limper, A. H., Lupu, R. & Leof, E. B., Jul 1 2018, In : FASEB Journal. 32, 7, p. 3803-3815 13 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Lung
Oxygenation
Pulmonary Fibrosis
Toxicity
2017
5 Citations (Scopus)

Basolateral delivery of the type i transforming growth factor beta receptor is mediated by a dominant-acting cytoplasmic motif

Yin, X., Kang, J. H., Andrianifahanana, M., Wang, Y., Jung, M. Y., Hernandez, D. M. & Leof, E. B., Oct 1 2017, In : Molecular Biology of the Cell. 28, 20, p. 2701-2711 11 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta Receptors
Epithelium
Nerve Growth Factor Receptor
Recycling
Point Mutation
15 Citations (Scopus)

Cell-penetrating peptides selectively targeting SMAD3 inhibit profibrotic TGF-β signaling

Kang, J. H., Jung, M. Y., Yin, X., Andrianifahanana, M., Hernandez, D. M. & Leof, E. B., Jun 30 2017, In : Journal of Clinical Investigation. 127, 7, p. 2541-2554 14 p.

Research output: Contribution to journalArticle

Sorting Nexins
Cell-Penetrating Peptides
Peptides
Bone Morphogenetic Protein 4
Human Immunodeficiency Virus Proteins
3 Citations (Scopus)

CorMatrix Wrapped Around the Adventitia of the Arteriovenous Fistula Outflow Vein Attenuates Venous Neointimal Hyperplasia

Yang, B., Kilari, S., Brahmbhatt, A., McCall, D. L., Torres, E. N., Leof, E. B., Mukhopadhyay, D. & Misra, S., Dec 1 2017, In : Scientific Reports. 7, 1, 14298.

Research output: Contribution to journalArticle

Adventitia
Arteriovenous Fistula
Hyperplasia
Veins
Neointima
2016
1 Citation (Scopus)
Physiognomy
Matrix Metalloproteinase 2
Hyperglycemia
Blood Vessels
Renal Dialysis
2 Citations (Scopus)

Patterns of Müllerian inhibiting substance type II and candidate type I receptors in epithelial ovarian cancer

Basal, E., Ayeni, T., Zhang, Q., Langstraat, C., Donahoe, P. K., Pepin, D., Yin, X., Leof, E. B. & Cliby, W. A., Mar 1 2016, In : Current Molecular Medicine. 16, 3, p. 222-231 10 p.

Research output: Contribution to journalArticle

Management information systems
Primary Cell Culture
Cell culture
Growth
Ascites
16 Citations (Scopus)

Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways

Andrianifahanana, M., Hernandez, D. M., Yin, X., Kang, J. H., Jung, M. Y., Wang, Y., Yi, E. S., Roden, A., Limper, A. H. & Leof, E. B., Nov 1 2016, In : FASEB Journal. 30, 11, p. 3733-3744 12 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Mitogen-Activated Protein Kinase Kinases
Up-Regulation
Chemical activation
Platelet-Derived Growth Factor Receptors
9 Citations (Scopus)

Tracking and therapeutic value of human adipose tissue-derived mesenchymal stem cell transplantation in reducing venous neointimal hyperplasia associated with arteriovenous fistula

Yang, B., Brahmbhatt, A., Torres, E. N., Thielen, B., McCall, D. L., Engel, S., Bansal, A., Pandey, M., Dietz, A. B., Leof, E. B., DeGrado, T. R., Mukhopadhyay, D. & Misra, S., May 1 2016, In : Radiology. 279, 2, p. 513-522 10 p.

Research output: Contribution to journalArticle

Mesenchymal Stem Cell Transplantation
Arteriovenous Fistula
Mesenchymal Stromal Cells
Hyperplasia
Adipose Tissue
2015
14 Citations (Scopus)

Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis

Wang, Y., Cao, Y., Yamada, S., Thirunavukkarasu, M., Nin, V., Joshi, M., Rishi, M. T., Bhattacharya, S., Camacho-Pereira, J., Sharma, A. K., Shameer, K., Kocher, J-P., Sanchez, J. A., Wang, E., Hoeppner, L. H., Dutta, S. K., Leof, E. B., Shah, V., Claffey, K. P., Chini, E. N. & 4 others, Simons, M., Terzic, A., Maulik, N. & Mukhopadhyay, D., Jun 27 2015, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 6, p. 1401-1412 12 p.

Research output: Contribution to journalArticle

Neuropilin-1
Cardiomyopathies
Homeostasis
Heart Failure
Peroxisome Proliferator-Activated Receptors
32 Citations (Scopus)

Cell Density Sensing Alters TGF-β Signaling in a Cell-Type-Specific Manner, Independent from Hippo Pathway Activation

Nallet-Staub, F., Yin, X., Gilbert, C., Marsaud, V., BenMimoun, S., Javelaud, D., Leof, E. B. & Mauviel, A., Mar 9 2015, In : Developmental Cell. 32, 5, p. 640-651 12 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Cell Count
Chemical activation
Growth Factor Receptors
Epithelial Cells
7 Citations (Scopus)

Sorting nexin 9 differentiates ligand-activated Smad3 from Smad2 for nuclear import and transforming growth factor β signaling

Wilkes, M. C., Repellin, C. E., Kang, J. H., Andrianifahanana, M., Yin, X. & Leof, E. B., Nov 1 2015, In : Molecular Biology of the Cell. 26, 21, p. 3879-3891 13 p.

Research output: Contribution to journalArticle

Sorting Nexins
Cell Nucleus Active Transport
Transforming Growth Factors
Ligands
Smad Proteins
6 Citations (Scopus)
Adventitia
Lentivirus
Arteriovenous Fistula
Vascular Endothelial Growth Factor A
Small Interfering RNA
2014
14 Citations (Scopus)

Adventitial delivery of lentivirus-shRNA-ADAMTS-1 reduces venous stenosis formation in arteriovenous fistula

Torres, E. C. N., Yang, B., Janardhanan, R., Brahmbhatt, A., Leof, E. B., Mukhopadhyay, D. & Misra, S., 2014, In : PLoS One. 9, 4, p. e94510

Research output: Contribution to journalArticle

Thrombospondin 1
Thrombospondins
Disintegrins
Adventitia
Lentivirus
31 Citations (Scopus)

Adventitial transduction of lentivirus-shRNA-VEGF-A in arteriovenous fistula reduces venous stenosis formation

Yang, B., Janardhanan, R., Vohra, P., Greene, E. L., Bhattacharya, S., Withers, S., Roy, B., Nieves Torres, E. C., Mandrekar, J., Leof, E. B., Mukhopadhyay, D. & Misra, S., Feb 2014, In : Kidney International. 85, 2, p. 289-306 18 p.

Research output: Contribution to journalArticle

Adventitia
Lentivirus
Arteriovenous Fistula
Vascular Endothelial Growth Factor A
Small Interfering RNA

Erratum to Imatinib mesylate causes genome-wide transcriptional changes in systemic sclerosis fibroblasts in vitro [Clin Exp Rheumatol, 30, 2 Suppl. 71, (2012) S86-S96]

Hinchcliff, M., Huang, C. C., Ishida, W., Fang, F., Lee, J., Jafari, N., Wilkes, M., Bhattacharyya, S., Leof, E. B. & Varga, J., 2014, In : Clinical and Experimental Rheumatology. 32, 1, p. 150 1 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Fibroblasts
Genome
Imatinib Mesylate
In Vitro Techniques
2013
48 Citations (Scopus)

IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver

Liu, C., Billadeau, D. D., Abdelhakim, H., Leof, E. B., Kaibuchi, K., Bernabeu, C., Bloom, G. S., Yang, L., Boardman, L. A., Shah, V. & Kang, N., Mar 1 2013, In : Journal of Clinical Investigation. 123, 3, p. 1138-1156 19 p.

Research output: Contribution to journalArticle

Pericytes
Tumor Microenvironment
Myofibroblasts
Hepatic Stellate Cells
Ubiquitination
29 Citations (Scopus)

Profibrotic TGFβ responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases

Andrianifahanana, M., Wilkes, M. C., Gupta, S. K., Rahimi, R. A., Repellin, C. E., Edens, M., Wittenberger, J., Yin, X., Maidl, E., Becker, J. & Leof, E. B., Nov 2013, In : FASEB Journal. 27, 11, p. 4444-4454 11 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Transforming Growth Factors
Protein-Tyrosine Kinases
Platelet-Derived Growth Factor
Ligands
20 Citations (Scopus)

Retromer maintains basolateral distribution of the type II TGF-β receptor via the recycling endosome

Yin, X., Murphy, S. J., Wilkes, M. C., Ji, Y. & Leof, E. B., Jul 15 2013, In : Molecular Biology of the Cell. 24, 14, p. 2285-2298 14 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Endosomes
Transforming Growth Factors
Cell Membrane
Maintenance
38 Citations (Scopus)

Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model

Janardhanan, R., Yang, B., Vohra, P., Roy, B., Withers, S., Bhattacharya, S., Mandrekar, J., Kong, H., Leof, E. B., Mukhopadhyay, D. & Misra, S., Aug 2013, In : Kidney International. 84, 2, p. 338-352 15 p.

Research output: Contribution to journalArticle

Simvastatin
Matrix Metalloproteinase 9
Hyperplasia
Blood Vessels
Renal Dialysis
2012
31 Citations (Scopus)

An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization

Xiong, X., Xu, Q., Huang, Y., Singh, R. D., Anderson, R., Leof, E. B., Hu, J. & Ling, K., Jan 1 2012, In : Molecular Biology of the Cell. 23, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

Cadherins
Cluster Analysis
Phosphotransferases
Adherens Junctions
Cell Membrane
7 Citations (Scopus)

Imatinib mesylate causes genome-wide transcriptional changes in systemic sclerosis fibroblasts in vitro

Hinchcliff, M., Huang, C. C., Ishida, W., Fang, F., Lee, J., Jafari, N., Wilkes, M., Bhattacharyya, S., Leof, E. B. & Varga, J., May 2012, In : Clinical and Experimental Rheumatology. 30, SUPPL.71

Research output: Contribution to journalArticle

Systemic Scleroderma
Fibroblasts
Genome
Gene Expression
Fibrosis
2011
8 Citations (Scopus)

Fibrosis, regeneration, and aging: Playing chess with evolution

Torres, V. & Leof, E. B., 2011, In : Journal of the American Society of Nephrology. 22, 8, p. 1393-1395 3 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-abl
Piperazines
Biological Evolution
Pyrimidines
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
35 Citations (Scopus)

Non-Smad transforming growth factor-β signaling regulated by focal adhesion kinase binding the p85 subunit of phosphatidylinositol 3-kinase

Hong, M., Wilkes, M. C., Penheiter, S. G., Gupta, S. K., Edens, M. & Leof, E. B., May 20 2011, In : Journal of Biological Chemistry. 286, 20, p. 17841-17850 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Focal Adhesion Protein-Tyrosine Kinases
Transforming Growth Factors
Fibroblasts
Protein-Tyrosine Kinases
2010
13 Citations (Scopus)

ERBB receptor activation is required for profibrotic responses to transforming growth factor β

Andrianifahanana, M., Wilkes, M. C., Repellin, C. E., Edens, M., Kottom, T. J., Rahimi, R. A. & Leof, E. B., Oct 1 2010, In : Cancer Research. 70, 19, p. 7421-7430 10 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Fibroblasts
Ligands
Growth Factor Receptors
Pathologic Processes
35 Citations (Scopus)
Tissue Inhibitor of Metalloproteinases
Myofibroblasts
Matrix Metalloproteinase 2
Hyperplasia
Renal Dialysis
54 Citations (Scopus)

Neuropilin-1 mediates divergent R-smad signaling and the myofibroblast phenotype

Cao, Y., Szabolcs, A., Dutta, S. K., Yaqoob, U., Jagavelu, K., Wang, L., Leof, E. B., Urrutia, R. A., Shah, V. & Mukhopadhyay, D., Oct 8 2010, In : Journal of Biological Chemistry. 285, 41, p. 31840-31848 9 p.

Research output: Contribution to journalArticle

Neuropilin-1
Myofibroblasts
Transforming Growth Factor beta
Phenotype
Fibroblasts
97 Citations (Scopus)

Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells

Cao, S., Yaqoob, U., Das, A., Shergill, U., Jagavelu, K., Huebert, R. C., Routray, C., Abdelmoneim, S., Vasdev, M., Leof, E. B., Charlton, M., Watts, R. J., Mukhopadhyay, D. & Shah, V., Jul 1 2010, In : Journal of Clinical Investigation. 120, 7, p. 2379-2394 16 p.

Research output: Contribution to journalArticle

Neuropilin-1
Hepatic Stellate Cells
Rodentia
Fibrosis
Liver Cirrhosis
93 Citations (Scopus)

Noncanonical TGF-β pathways, mTORC1 and Abl, in renal interstitial fibrogenesis

Wang, S., Wilkes, M. C., Leof, E. B. & Hirschberg, R., Jan 2010, In : American Journal of Physiology - Renal Physiology. 298, 1

Research output: Contribution to journalArticle

Transforming Growth Factors
Kidney
Sirolimus
p21-Activated Kinases
Fibroblasts
40 Citations (Scopus)

Type II transforming growth factor-β receptor recycling is dependent upon the clathrin adaptor protein Dab2

Penheiter, S. G., Singh, R. D., Repellin, C. E., Wilkes, M. C., Edens, M., Howe, P. H., Pagano, R. E. & Leof, E. B., Nov 15 2010, In : Molecular Biology of the Cell. 21, 22, p. 4009-4019 11 p.

Research output: Contribution to journalArticle

Vesicular Transport Adaptor Proteins
Growth Factor Receptors
Transforming Growth Factors
Proteins
Endosomes
2009
64 Citations (Scopus)

A non-Smad mechanism of fibroblast activation by transforming growth factor-β via c-Abl and Egr-1: Selective modulation by imatinib mesylate

Bhattacharyya, S., Ishida, W., Wu, M., Wilkes, M., Mori, Y., Hinchcliff, M., Leof, E. B. & Varga, J., Mar 12 2009, In : Oncogene. 28, 10, p. 1285-1297 13 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Intercellular Signaling Peptides and Proteins
Fibroblasts
Fibrosis
Phosphotransferases
64 Citations (Scopus)

Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-β

Rahimi, R. A., Andrianifahanana, M., Wilkes, M. C., Edens, M., Kottom, T. J., Blenis, J. & Leof, E. B., Jan 1 2009, In : Cancer Research. 69, 1, p. 84-93 10 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Sirolimus
Fibroblasts
Phosphatidylinositol 3-Kinase
Growth
27 Citations (Scopus)

Erbin and the NF2 Tumor Suppressor Merlin Cooperatively Regulate Cell-Type-Specific Activation of PAK2 by TGF-β

Wilkes, M. C., Repellin, C. E., Hong, M., Bracamonte, M., Penheiter, S. G., Borg, J. P. & Leof, E. B., Mar 17 2009, In : Developmental Cell. 16, 3, p. 433-444 12 p.

Research output: Contribution to journalArticle

Neurofibromin 2
Transforming Growth Factor beta
Tumors
Chemical activation
Neoplasms
3 Citations (Scopus)

TGFβ versatility: PI3K as a critical mediator of distinct cell type and context specific responses

Rahimi, R. A. & Leof, E. B., Jun 15 2009, In : Cell Cycle. 8, 12, p. 1813-1814 2 p.

Research output: Contribution to journalArticle

Smad Proteins
Phosphatidylinositol 3-Kinase
Proto-Oncogene Proteins c-sis
Protein Kinase Inhibitors
Phosphatidylinositol 3-Kinases
2008
7 Citations (Scopus)

Histologic studies of the intraocular toxicity of imatinib mesylate in rabbits

Kitzmann, A. S., Baratz, K., Mohney, B. G., Pulido, J. S., Cameron, J. D., Lee, E. S. & Leof, E. B., May 2008, In : Eye. 22, 5, p. 712-714 3 p.

Research output: Contribution to journalArticle

Rabbits
Papilledema
Imatinib Mesylate
Subretinal Fluid
Intravitreal Injections
99 Citations (Scopus)

Platelet-Derived Growth Factor Signaling Through Ephrin-B2 Regulates Hepatic Vascular Structure and Function

Semela, D., Das, A., Langer, D., Kang, N., Leof, E. B. & Shah, V., Aug 2008, In : Gastroenterology. 135, 2

Research output: Contribution to journalArticle

Ephrin-B2
Hepatic Stellate Cells
Platelet-Derived Growth Factor
Blood Vessels
Pericytes
2007
18 Citations (Scopus)

A unique element in the cytoplasmic tail of the type II transforming growth factor-β receptor controls basolateral delivery

Murphy, S. J., Shapira, K. E., Henis, Y. I. & Leof, E. B., Oct 2007, In : Molecular Biology of the Cell. 18, 10, p. 3788-3799 12 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
Hemagglutinins
Fluorescence Recovery After Photobleaching
Point Mutation
34 Citations (Scopus)

Phase I trial of sirolimus combined with radiation and cisplatin in non-small cell lung cancer

Sarkaria, J. N., Schwingler, P., Schild, S. E., Grogan, P. T., Mladek, A. C., Mandrekar, S. J., Tan, A. D., Kobayashi, T., Marks, R. S., Kita, H., Miller, R. C., Limper, A. H. & Leof, E. B., Aug 2007, In : Journal of Thoracic Oncology. 2, 8, p. 751-757 7 p.

Research output: Contribution to journalArticle

Sirolimus
Non-Small Cell Lung Carcinoma
Cisplatin
Radiation
Thorax
21 Citations (Scopus)

Phosphorylation of the cyclic AMP response element binding protein mediates transforming growth factor β-induced downregulation of cyclin A in vascular smooth muscle cells

Kamiya, K., Sakakibara, K., Ryer, E. J., Hom, R. P., Leof, E. B., Kent, K. C. & Liu, B., May 2007, In : Molecular and Cellular Biology. 27, 9, p. 3489-3498 10 p.

Research output: Contribution to journalArticle

Cyclin A
Cyclic AMP Response Element-Binding Protein
Transforming Growth Factors
Vascular Smooth Muscle
Smooth Muscle Myocytes
286 Citations (Scopus)

TGF-β signaling: A tale of two responses

Rahimi, R. A. & Leof, E. B., Oct 15 2007, In : Journal of Cellular Biochemistry. 102, 3, p. 593-608 16 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Smad Proteins
Fibroblasts
Carcinogenesis
Cell Growth Processes
41 Citations (Scopus)

Transforming growth factor β signaling via ras in mesenchymal cells requires p21-activated kinase 2 for extracellular signal-regulated kinase-dependent transcriptional responses

Suzuki, K., Wilkes, M. C., Garamszegi, N., Edens, M. & Leof, E. B., Apr 15 2007, In : Cancer Research. 67, 8, p. 3673-3682 10 p.

Research output: Contribution to journalArticle

p21-Activated Kinases
Extracellular Signal-Regulated MAP Kinases
Transforming Growth Factors
Growth
Phosphorylation
2006
62 Citations (Scopus)
Phosphatidylinositol 3-Kinase
Transforming Growth Factors
Chemical activation
Fibroblasts
Protein-Tyrosine Kinases
2005
199 Citations (Scopus)

Imatinib mesylate blocks a non-Smad TGF-β pathway and reduces renal fibrogenesis in vivo

Wang, S., Wilkes, M. C., Leof, E. B. & Hirschberg, R., Jan 2005, In : FASEB Journal. 19, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

transforming growth factors
Transforming Growth Factors
kidneys
p21-Activated Kinases
Kidney
137 Citations (Scopus)

Transforming growth factor-β activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2

Wilkes, M. C., Mitchell, H., Penheiter, S. G., Doré, J. J., Suzuki, K., Edens, M., Sharma, D. K., Pagano, R. E. & Leof, E. B., Nov 15 2005, In : Cancer Research. 65, 22, p. 10431-10440 10 p.

Research output: Contribution to journalArticle

p21-Activated Kinases
Phosphatidylinositol 3-Kinase
Transforming Growth Factors
Fibroblasts
Dynamins
2004
30 Citations (Scopus)

Differential trafficking of transforming growth factor-β receptors and ligand in polarized epithelial cells

Murphy, S. J., Doré, J. J. E., Edens, M., Coffey, R. J., Barnard, J. A., Mitchell, H., Wilkes, M. & Leof, E. B., Jun 2004, In : Molecular Biology of the Cell. 15, 6, p. 2853-2862 10 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
Epithelial Cells
Ligands
Madin Darby Canine Kidney Cells
458 Citations (Scopus)

Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis

Daniels, C. E., Wilkes, M. C., Edens, M., Kottom, T. J., Murphy, S. J., Limper, A. H. & Leof, E. B., Nov 2004, In : Journal of Clinical Investigation. 114, 9, p. 1308-1316 9 p.

Research output: Contribution to journalArticle

Bleomycin
Idiopathic Pulmonary Fibrosis
Fibrosis
Cytokines
Lung
138 Citations (Scopus)

Ligand-dependent and -independent transforming growth factor-β receptor recycling regulated by clathrin-mediated endocytosis and rab11

Mitchell, H., Choudhury, A., Pagano, R. E. & Leof, E. B., Sep 2004, In : Molecular Biology of the Cell. 15, 9, p. 4166-4178 13 p.

Research output: Contribution to journalArticle

Clathrin
Growth Factor Receptors
Transforming Growth Factors
Endocytosis
Recycling
2003
100 Citations (Scopus)

Cell-Type-Specific Activation of PAK2 by Transforming Growth Factor β Independent of Smad2 and Smad3

Wilkes, M. C., Murphy, S. J., Garamszegi, N. & Leof, E. B., Dec 2003, In : Molecular and Cellular Biology. 23, 23, p. 8878-8889 12 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Fibroblasts
Epithelial Cells
Growth
Morpholinos
2002
149 Citations (Scopus)

Internalization-dependent and -independent requirements for transforming growth factor β receptor signaling via the Smad pathway

Penheiter, S. G., Mitchell, H., Garamszegi, N., Edens, M., Doré, J. J. E. & Leof, E. B., 2002, In : Molecular and Cellular Biology. 22, 13, p. 4750-4759 10 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
Phosphorylation
Inhibitory Smad Proteins
Transport Vesicles
94 Citations (Scopus)

Transforming growth factor-β receptors interact with AP2 by direct binding to β2 subunit

Yao, D., Ehrlich, M., Henis, Y. I. & Leof, E. B., Nov 1 2002, In : Molecular Biology of the Cell. 13, 11, p. 4001-4012 12 p.

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
Clathrin
Cytoplasmic and Nuclear Receptors
Vesicular Transport Adaptor Proteins