Projects per year
Fingerprint Dive into the research topics where Eduardo Nunes Chini is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Cyclic ADP-Ribose
Medicine & Life Sciences
NAD
Medicine & Life Sciences
ADP-ribosyl Cyclase
Medicine & Life Sciences
NAD+ Nucleosidase
Medicine & Life Sciences
Second Messenger Systems
Medicine & Life Sciences
Mesangial Cells
Medicine & Life Sciences
Rats
Chemical Compounds
Metabolism
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2003 2019
Role of CD38 in NAD metabolism: from the basic biology of aging to translation
Project: Research project
Molecular mechanisms of fatty liver disease: role of the protein DBC1
7/1/09 → 6/30/15
Project: Research project
Fatty Liver
Liver Diseases
Breast Neoplasms
Proteins
Adenylate Kinase
The Sir2-p53-IGF link in mammalian life-span control
Scrable, H. J. & Chini, E. N.
12/1/04 → 7/31/17
Project: Research project
Health
Insulin-Like Growth Factor I
Transgenic Mice
Assisted Reproductive Techniques
Protein Isoforms
Mayo Clinic SPORE in Pancreatic Cancer
Cohen, P. A., Urrutia, R. A., De Andrade, M., Chari, S. T., Lingle, W. L., Billadeau, D. D., Petersen, G. M., Couch, F. J., Mukhopadhyay, D., Chini, E. N., Smyrk, T. C., Oberg, A. L., Gendler, S. J., Couch, F. J., Mukherjee, P., Mukherjee, P., Andrade, M., Fernandez-Zapico, M. E. & Billadeau, D. D.
9/29/03 → 8/31/19
Project: Research project
Pancreatic Neoplasms
Research
Biostatistics
Glycogen Synthase Kinase 3
Neoplasms
Research Output 1990 2019
1
Citation
(Scopus)
Targeting CD38 enhances the antileukemic activity of ibrutinib in chronic lymphocytic leukemia
Manna, A., Aulakh, S., Jani, P., Ahmed, S., Akhtar, S., Coignet, M., Heckman, M., Meghji, Z., Bhatia, K., Sharma, A., Sher, T., Alegria, V., Malavasi, F., Chini, E. N., Chanan Khan, A. A., Ailawadhi, S. & Paulus, A., Jan 1 2019, In : Clinical Cancer Research. 25, 13, p. 3974-3985 12 p.Research output: Contribution to journal › Article
B-Cell Chronic Lymphocytic Leukemia
Heterografts
B-Lymphocytes
Antibody-Dependent Cell Cytotoxicity
PCI 32765
9
Citations
(Scopus)
Targeting senescent cells alleviates obesity-induced metabolic dysfunction
Palmer, A. K., Xu, M., Zhu, Y., Pirtskhalava, T., Weivoda, M., Hachfeld, C. M., Prata, L. G., van Dijk, T. H., Verkade, E., Casaclang-Verzosa, G., Johnson, K. O., Cubro, H., Doornebal, E. J., Ogrodnik, M., Jurk, D., Jensen, M. D., Chini, E. N., Miller, J. D., Matveyenko, A. V., Stout, M. B. & 13 others, , Jun 1 2019, In : Aging Cell. 18, 3, e12950.Research output: Contribution to journal › Article
Open Access
Obesity
Adipose Tissue
Obese Mice
Insulin Resistance
p16 Genes
2
Citations
(Scopus)
The Multi-faceted Ecto-enzyme CD38: Roles in immunomodulation, cancer, aging, and metabolic diseases
Hogan, K. A., Chini, C. C. S. & Chini, E. N., Jan 1 2019, In : Frontiers in immunology. 10, MAY, 1187.Research output: Contribution to journal › Review article
Open Access
Immunomodulation
Metabolic Diseases
NAD
Enzymes
Neoplasms
5
Citations
(Scopus)
The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD + decline
Chini, C., Hogan, K. A., Warner, G. M., Tarragó, M. G., Peclat, T. R., Tchkonia, T., Kirkland, J. L. & Chini, E. N., May 28 2019, In : Biochemical and Biophysical Research Communications. 513, 2, p. 486-493 8 p.Research output: Contribution to journal › Article
Open Access
NAD+ Nucleosidase
NAD
Cell Aging
Aging of materials
Phenotype
26
Citations
(Scopus)
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
Tarragó, M. G., Chini, C. C. S., Kanamori, K. S., Warner, G. M., Caride, A., de Oliveira, G. C., Rud, M., Samani, A., Hein, K. Z., Huang, R., Jurk, D., Cho, D. S., Boslett, J. J., Miller, J. D., Zweier, J. L., Passos, J., Doles, J., Becherer, D. J. & Chini, E. N., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.Research output: Contribution to journal › Article
NAD
NAD+ Nucleosidase
Telomere
DNA Damage
Sirtuins