Eduardo Nunes Chini, MD, PhD

Professor

  • 3608 Citations
  • 36 h-Index
1990 …2019
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Projects 2003 2019

Mayo Clinic SPORE in Pancreatic Cancer

Cohen, P. A., Urrutia, R. A., De Andrade, M., Chari, S. T., Lingle, W. L., Billadeau, D. D., Petersen, G. M., Couch, F. J., Mukhopadhyay, D., Chini, E. N., Smyrk, T. C., Oberg, A. L., Gendler, S. J., Couch, F. J., Mukherjee, P., Mukherjee, P., Andrade, M. & Fernandez-Zapico, M. E.

National Institutes of Health

9/29/038/31/19

Project: Research project

Pancreatic Neoplasms
Research
Biostatistics
Glycogen Synthase Kinase 3
Neoplasms
Fatty Liver
Liver Diseases
Breast Neoplasms
Proteins
Adenylate Kinase
Health
Insulin-Like Growth Factor I
Transgenic Mice
Assisted Reproductive Techniques
Protein Isoforms

Research Output 1990 2019

  • 3608 Citations
  • 36 h-Index
  • 107 Article
  • 1 Review article

The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD + decline

Chini, C., Hogan, K. A., Warner, G. M., Tarragó, M. G., Peclat, T. R., Tchkonia, T., Kirkland, J. L. & Chini, E. N., May 28 2019, In : Biochemical and Biophysical Research Communications. 513, 2, p. 486-493 8 p.

Research output: Contribution to journalArticle

Open Access
NAD+ Nucleosidase
NAD
Cell Aging
Aging of materials
Phenotype
11 Citations (Scopus)

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Tarragó, M. G., Chini, C. C. S., Kanamori, K. S., Warner, G. M., Caride, A., de Oliveira, G. C., Rud, M., Samani, A., Hein, K. Z., Huang, R., Jurk, D., Cho, D. S., Boslett, J. J., Miller, J. D., Zweier, J. L., Passos, J. F., Doles, J., Becherer, D. J. & Chini, E. N., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

NAD
NAD+ Nucleosidase
Telomere
DNA Damage
Sirtuins
5 Citations (Scopus)

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides

Boslett, J., Helal, M., Chini, E. N. & Zweier, J. L., May 1 2018, In : Journal of Molecular and Cellular Cardiology. 118, p. 81-94 14 p.

Research output: Contribution to journalArticle

Nucleotides
NADP
Wounds and Injuries
NAD
Reperfusion

Rho GTPase effectors and NAD metabolism in cancer immune suppression

Chaker, M., Minden, A., Chen, S., Weiss, R. H., Chini, E. N., Mahipal, A. & Azmi, A. S., Jan 2 2018, In : Expert Opinion on Therapeutic Targets. 22, 1, p. 9-17 9 p.

Research output: Contribution to journalReview article

rho GTP-Binding Proteins
GTP Phosphohydrolases
Metabolism
NAD
Expert Testimony
11 Citations (Scopus)

The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of Aging

Chini, E. N., Chini, C. C. S., Espindola Netto, J. M., de Oliveira, G. C. & van Schooten, W., Jan 1 2018, (Accepted/In press) In : Trends in Pharmacological Sciences.

Research output: Contribution to journalArticle

NAD+ Nucleosidase
NAD
Aging of materials
Pharmacology
Neoplasms