Eduardo Nunes Chini, MD, PhD


  • 3608 Citations
  • 36 h-Index
1990 …2019
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Projects 2003 2019

Mayo Clinic SPORE in Pancreatic Cancer

Cohen, P. A., Urrutia, R. A., De Andrade, M., Chari, S. T., Lingle, W. L., Billadeau, D. D., Petersen, G. M., Couch, F. J., Mukhopadhyay, D., Chini, E. N., Smyrk, T. C., Oberg, A. L., Gendler, S. J., Couch, F. J., Mukherjee, P., Mukherjee, P., Andrade, M. & Fernandez-Zapico, M. E.

National Institutes of Health


Project: Research project

Pancreatic Neoplasms
Glycogen Synthase Kinase 3
Fatty Liver
Liver Diseases
Breast Neoplasms
Adenylate Kinase
Insulin-Like Growth Factor I
Transgenic Mice
Assisted Reproductive Techniques
Protein Isoforms

Research Output 1990 2019

  • 3608 Citations
  • 36 h-Index
  • 107 Article
  • 1 Review article

The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD + decline

Chini, C., Hogan, K. A., Warner, G. M., Tarragó, M. G., Peclat, T. R., Tchkonia, T., Kirkland, J. L. & Chini, E. N., May 28 2019, In : Biochemical and Biophysical Research Communications. 513, 2, p. 486-493 8 p.

Research output: Contribution to journalArticle

Open Access
NAD+ Nucleosidase
Cell Aging
Aging of materials
11 Citations (Scopus)

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Tarragó, M. G., Chini, C. C. S., Kanamori, K. S., Warner, G. M., Caride, A., de Oliveira, G. C., Rud, M., Samani, A., Hein, K. Z., Huang, R., Jurk, D., Cho, D. S., Boslett, J. J., Miller, J. D., Zweier, J. L., Passos, J. F., Doles, J., Becherer, D. J. & Chini, E. N., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

NAD+ Nucleosidase
DNA Damage
5 Citations (Scopus)

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides

Boslett, J., Helal, M., Chini, E. N. & Zweier, J. L., May 1 2018, In : Journal of Molecular and Cellular Cardiology. 118, p. 81-94 14 p.

Research output: Contribution to journalArticle

Wounds and Injuries

Rho GTPase effectors and NAD metabolism in cancer immune suppression

Chaker, M., Minden, A., Chen, S., Weiss, R. H., Chini, E. N., Mahipal, A. & Azmi, A. S., Jan 2 2018, In : Expert Opinion on Therapeutic Targets. 22, 1, p. 9-17 9 p.

Research output: Contribution to journalReview article

rho GTP-Binding Proteins
GTP Phosphohydrolases
Expert Testimony
11 Citations (Scopus)

The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of Aging

Chini, E. N., Chini, C. C. S., Espindola Netto, J. M., de Oliveira, G. C. & van Schooten, W., Jan 1 2018, (Accepted/In press) In : Trends in Pharmacological Sciences.

Research output: Contribution to journalArticle

NAD+ Nucleosidase
Aging of materials