Eduardo Nunes Chini, MD, PhD

  • 3894 Citations
  • 37 Scopus h-Index
1990 …2019
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  • 1 Similar Profiles
Cyclic ADP-Ribose Medicine & Life Sciences
NAD Medicine & Life Sciences
ADP-ribosyl Cyclase Medicine & Life Sciences
NAD+ Nucleosidase Medicine & Life Sciences
Sea Urchins Medicine & Life Sciences
Second Messenger Systems Medicine & Life Sciences
Mesangial Cells Medicine & Life Sciences
Rats Chemical Compounds

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Projects 2003 2019

Fatty Liver
Liver Diseases
Breast Neoplasms
Adenylate Kinase
Insulin-Like Growth Factor I
Transgenic Mice
Assisted Reproductive Techniques
Protein Isoforms

Mayo Clinic SPORE in Pancreatic Cancer

Cohen, P. A., Urrutia, R. A., De Andrade, M., Chari, S. T., Lingle, W. L., Billadeau, D. D., Petersen, G. M., Couch, F. J., Mukhopadhyay, D., Chini, E. N., Smyrk, T. C., Oberg, A. L., Gendler, S. J., Couch, F. J., Mukherjee, P., Mukherjee, P., Andrade, M., Fernandez-Zapico, M. E. & Billadeau, D. D.

National Institutes of Health


Project: Research project

Pancreatic Neoplasms
Glycogen Synthase Kinase 3

Research Output 1990 2019

  • 3894 Citations
  • 37 Scopus h-Index
  • 110 Article
  • 2 Review article

A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo

Santos, L., Colman, L., Contreras, P., Chini, C. C., Carlomagno, A., Leyva, A., Bresque, M., Marmisolle, I., Quijano, C., Durán, R., Irigoín, F., Prieto-Echagüe, V., Vendelbo, M. H., Sotelo-Silveira, J. R., Chini, E. N., Badano, J. L., Calliari, A. J. & Escande, C., Dec 1 2019, In : Scientific reports. 9, 1, 14381.

Research output: Contribution to journalArticle

Open Access
Breast Neoplasms
Liver Regeneration
Cell Cycle
1 Citation (Scopus)

Targeting CD38 enhances the antileukemic activity of ibrutinib in chronic lymphocytic leukemia

Manna, A., Aulakh, S., Jani, P., Ahmed, S., Akhtar, S., Coignet, M., Heckman, M., Meghji, Z., Bhatia, K., Sharma, A., Sher, T., Alegria, V., Malavasi, F., Chini, E. N., Chanan Khan, A. A., Ailawadhi, S. & Paulus, A., Jan 1 2019, In : Clinical Cancer Research. 25, 13, p. 3974-3985 12 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Antibody-Dependent Cell Cytotoxicity
PCI 32765
17 Citations (Scopus)

Targeting senescent cells alleviates obesity-induced metabolic dysfunction

Palmer, A. K., Xu, M., Zhu, Y., Pirtskhalava, T., Weivoda, M., Hachfeld, C. M., Prata, L. G., van Dijk, T. H., Verkade, E., Casaclang-Verzosa, G., Johnson, K. O., Cubro, H., Doornebal, E. J., Ogrodnik, M., Jurk, D., Jensen, M. D., Chini, E. N., Miller, J. D., Matveyenko, A. V., Stout, M. B. & 13 others, Schafer, M. J., White, T. A., Hickson, L., Demaria, M., Garovic, V. D., Grande, J. P., Arriaga, E. A., Kuipers, F., von Zglinicki, T., LeBrasseur, N. K., Campisi, J., Tchkonia, T. & Kirkland, J. L., Jun 1 2019, In : Aging Cell. 18, 3, e12950.

Research output: Contribution to journalArticle

Open Access
Adipose Tissue
Obese Mice
Insulin Resistance
p16 Genes
3 Citations (Scopus)

The Multi-faceted Ecto-enzyme CD38: Roles in immunomodulation, cancer, aging, and metabolic diseases

Hogan, K. A., Chini, C. C. S. & Chini, E. N., Jan 1 2019, In : Frontiers in immunology. 10, MAY, 1187.

Research output: Contribution to journalReview article

Open Access
Metabolic Diseases
7 Citations (Scopus)

The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD + decline

Chini, C., Hogan, K. A., Warner, G. M., Tarragó, M. G., Peclat, T. R., Tchkonia, T., Kirkland, J. L. & Chini, E. N., May 28 2019, In : Biochemical and Biophysical Research Communications. 513, 2, p. 486-493 8 p.

Research output: Contribution to journalArticle

Open Access
NAD+ Nucleosidase
Cell Aging
Aging of materials