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Dennis W Dickson, MD

Professor

  • 101693 Citations
  • 151 h-Index
1981 …2021
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Alzheimer Disease Medicine & Life Sciences
Lewy Body Disease Medicine & Life Sciences
Progressive Supranuclear Palsy Medicine & Life Sciences
Pathology Medicine & Life Sciences
Frontotemporal Lobar Degeneration Medicine & Life Sciences
Dementia Medicine & Life Sciences
Brain Medicine & Life Sciences
Frontotemporal Dementia Medicine & Life Sciences

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Projects 1982 2021

Identifying genes and Pathways that impact Tau Toxicity in FTD

Dickson, D. W. & Petrucelli, L.

National Institutes of Health

9/30/16 → 6/30/21

Project: Research project

Tauopathies
Genes
Progressive Supranuclear Palsy
Research
Parkinsonian Disorders

Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion

Boylan, K. B., Petrucelli, L. & Dickson, D. W.

National Institutes of Health

9/30/14 → 6/30/19

Project: Research project

Amyotrophic Lateral Sclerosis
Frontotemporal Lobar Degeneration
Methylation
RNA-Binding Proteins
Histones

TEACHING NURSING HOME

Dickson, D. W., Dickson, D. W., Lee, S., Hall, C., Verghese, J. O. E., Lipton, R., Sliwinski, M. J., Lee, S., Verghese, J. O. E., Sliwinski, M. J., Marantz, P., Grober, E., Cohen, D., Ritter, W., Hamerman, D., Golden, R., Katzman, R., Wolfson, L., Crystal, H., Buschke, H., Lipton, R., Crystal, H. & Buschke, H.

National Institutes of Health

9/29/82 → 5/31/21

Project: Research project

Amyloid
Pathology
Dementia
Nursing Homes
Alzheimer Disease

Apoptotic neuronal cells serve as sources for spreading of human a-synuclein pathology in the brain

Dickson, D. W.

National Institutes of Health

9/30/16 → 8/31/18

Project: Research project

Synucleins
Parkinson Disease
Pathology
Nuclear Envelope
Brain

Identification of genetic risk factors that predict disease onset, susceptibility

Ross, O. A., Wszolek, Z. K., Rademakers, R. V., Dickson, D. W. & Farrer, M.

National Institutes of Health

9/1/10 → 6/30/17

Project: Research project

Parkinsonian Disorders
Synucleins
Parkinson Disease
Research
Molecular Biology

Research Output 1981 2019

1 Citation (Scopus)

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Chew, J., Cook, C., Gendron, T. D., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. J. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 1 p.

Research output: Contribution to journal › Article

TDP-43 Proteinopathies
Dipeptides
RNA
Proteins
Antisense RNA

A comprehensive screening of copy number variability in dementia with Lewy bodies

Kun-Rodrigues, C., Orme, T., Carmona, S., Hernandez, D. G., Ross, O. A., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L. & 48 othersHonig, L. S., Marder, K., Lemstra, A., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff Radford, N. R., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J., Guerreiro, R. & Bras, J., Mar 1 2019, In : Neurobiology of Aging. 75, p. 223.e1-223.e10

Research output: Contribution to journal › Article

Lewy Body Disease
Genome
Neurodegenerative Diseases
Genes
Dementia
1 Citation (Scopus)

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journal › Article

LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease

Association of MAPT Subhaplotypes with Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology

Heckman, M. G., Brennan, R. R., Labbé, C., Soto, A. I., Koga, S., Deture, M., Murray, M. E., Petersen, R. C., Boeve, B. F., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Rademakers, R. V., Dickson, D. W. & Ross, O. A., Jan 1 2019, In : JAMA neurology.

Research output: Contribution to journal › Article

Progressive Supranuclear Palsy
Microtubule-Associated Proteins
Pathology
Haplotypes
Odds Ratio

Brain atrophy in primary age-related tauopathy is linked to transactive response DNA-binding protein of 43 kDa

Josephs, K. A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Whitwell, J. L. & Dickson, D. W., Jan 1 2019, In : Alzheimer's and Dementia.

Research output: Contribution to journal › Article

Tauopathies
DNA-Binding Proteins
Atrophy
Brain
Amygdala