• 108627 Citations
  • 156 Scopus h-Index
1981 …2021
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Research Output 1981 2020

2020

Aberrant Accumulation of BRCA1 in Alzheimer Disease and Other Tauopathies

Nakamura, M., Kaneko, S., Dickson, D. W. & Kusaka, H., Jan 1 2020, In : Journal of Neuropathology and Experimental Neurology. 79, 1, p. 22-33 12 p.

Research output: Contribution to journalArticle

Tauopathies
Alzheimer Disease
Pick Disease of the Brain
DNA Damage
Progressive Supranuclear Palsy
2 Citations (Scopus)

Association between contact sports participation and chronic traumatic encephalopathy: a retrospective cohort study

Bieniek, K. F., Blessing, M. M., Heckman, M. G., Diehl, N. N., Serie, A. M., Paolini, M. A., Boeve, B. F., Savica, R., Reichard, R. R. & Dickson, D. W., Jan 1 2020, In : Brain Pathology. 30, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

Open Access
Sports
Cohort Studies
Retrospective Studies
Pathology
Athletes
2019
2 Citations (Scopus)

4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration

Saijo, E., Metrick, M. A., Koga, S., Parchi, P., Litvan, I., Spina, S., Boxer, A., Rojas, J. C., Galasko, D., Kraus, A., Rossi, M., Newell, K., Zanusso, G., Grinberg, L. T., Seeley, W. W., Ghetti, B., Dickson, D. W. & Caughey, B., Jan 1 2019, (Accepted/In press) In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Tauopathies
Progressive Supranuclear Palsy
Cerebrospinal Fluid
Seeds
9 Citations (Scopus)

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Chew, J., Cook, C., Gendron, T. D., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 1 p.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Dipeptides
RNA
Proteins
Antisense RNA
1 Citation (Scopus)

A comprehensive screening of copy number variability in dementia with Lewy bodies

Kun-Rodrigues, C., Orme, T., Carmona, S., Hernandez, D. G., Ross, O. A., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L. & 48 others, Honig, L. S., Marder, K., Lemstra, A., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff Radford, N. R., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J., Guerreiro, R. & Bras, J., Mar 1 2019, In : Neurobiology of Aging. 75, p. 223.e1-223.e10

Research output: Contribution to journalArticle

Lewy Body Disease
Genome
Neurodegenerative Diseases
Genes
Dementia
7 Citations (Scopus)

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Aug 1 2019, In : Acta neuropathologica. 138, 2, p. 237-250 14 p.

Research output: Contribution to journalArticle

Open Access
Lewy Body Disease
Frontotemporal Dementia
Alzheimer Disease
Mutation
Neurodegenerative Diseases
1 Citation (Scopus)

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Bejanin, A., Murray, M. E., Martin, P., Botha, H., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Chételat, G., Kantarci, K., Jack, C. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Giannini, C., Parisi, J. E., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Nov 1 2019, In : Brain : a journal of neurology. 142, 11, p. 3621-3635 15 p.

Research output: Contribution to journalArticle

Temporal Lobe
Pathology
Alzheimer Disease
Frontotemporal Lobar Degeneration
Lewy Bodies
4 Citations (Scopus)

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
1 Citation (Scopus)

Association of MAPT H1 subhaplotypes with neuropathology of lewy body disease

Heckman, M. G., Kasanuki, K., Brennan, R. R., Labbé, C., Vargas, E. R., Soto, A. I., Murray, M. E., Koga, S., Dickson, D. W. & Ross, O. A., Jan 1 2019, In : Movement Disorders.

Research output: Contribution to journalArticle

Lewy Body Disease
Microtubule-Associated Proteins
Haplotypes
Tyrosine 3-Monooxygenase
Lewy Bodies
6 Citations (Scopus)

Association of MAPT Subhaplotypes with Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology

Heckman, M. G., Brennan, R. R., Labbé, C., Soto, A. I., Koga, S., Deture, M., Murray, M. E., Petersen, R. C., Boeve, B. F., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Rademakers, R. V., Dickson, D. W. & Ross, O. A., Jan 1 2019, In : JAMA neurology.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Microtubule-Associated Proteins
Pathology
Haplotypes
Odds Ratio
2 Citations (Scopus)
Tauopathies
DNA-Binding Proteins
Atrophy
Brain
Amygdala

C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy

Cali, C. P., Patino, M., Tai, Y. K., Ho, W. Y., McLean, C. A., Morris, C. M., Seeley, W. W., Miller, B. L., Gaig, C., Vonsattel, J. P. G., White, C. L., Roeber, S., Kretzschmar, H., Troncoso, J. C., Troakes, C., Gearing, M., Ghetti, B., Van Deerlin, V. M., Lee, V. M. Y., Trojanowski, J. Q. & 6 others, Mok, K. Y., Ling, H., Dickson, D. W., Schellenberg, G. D., Ling, S. C. & Lee, E. B., Nov 1 2019, In : Acta neuropathologica. 138, 5, p. 795-811 17 p.

Research output: Contribution to journalArticle

Autophagy
Amyotrophic Lateral Sclerosis
Neurodegenerative Diseases
Autopsy
Clustered Regularly Interspaced Short Palindromic Repeats
1 Citation (Scopus)

Cerebrovascular pathology presenting as corticobasal syndrome: An autopsy case series of “vascular CBS”

Koga, S., Roemer, S. F., Kasanuki, K. & Dickson, D. W., Nov 2019, In : Parkinsonism and Related Disorders. 68, p. 79-84 6 p.

Research output: Contribution to journalArticle

Blood Vessels
Autopsy
Pathology
Frontal Lobe
Pyramidal Tracts
1 Citation (Scopus)

Clinicopathologic subtype of Alzheimer's disease presenting as corticobasal syndrome

Sakae, N., Josephs, K. A., Litvan, I., Murray, M. E., Duara, R., Uitti, R. J., Wszolek, Z. K., van Gerpen, J., Graff Radford, N. R. & Dickson, D. W., Sep 1 2019, In : Alzheimer's and Dementia. 15, 9, p. 1218-1228 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Substantia Nigra
Pathology
Extremities
Apraxias
3 Citations (Scopus)

CNS small vessel disease: A clinical review

Cannistraro, R. J., Badi, M., Eidelman, B. H., Dickson, D. W., Middlebrooks, E. H. & Meschia, J. F., Jun 11 2019, In : Neurology. 92, 24, p. 1146-1156 11 p.

Research output: Contribution to journalReview article

Dementia
Cerebral Amyloid Angiopathy
Hypertension
Inborn Genetic Diseases
Diffusion Tensor Imaging

Coexistence of Progressive Supranuclear Palsy with Pontocerebellar Atrophy and Myotonic Dystrophy Type 1

Koga, S., Eric Ahlskog, J., DeTure, M. A., Baker, M., Roemer, S. F., Konno, T., Rademakers, R., Ross, O. A. & Dickson, D. W., Jan 1 2019, In : Journal of Neuropathology and Experimental Neurology. 78, 8, p. 756-762 7 p.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Myotonic Dystrophy
Atrophy
Multiple System Atrophy
Cerebellar Ataxia
1 Citation (Scopus)

Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy

Koller, E. J., Gonzalez De La Cruz, E., Machula, T., Ibanez, K. R., Lin, W. L., Williams, T., Riffe, C. J., Ryu, D., Strang, K. H., Liu, X., Janus, C., Golde, T. E., Dickson, D., Giasson, B. I. & Chakrabarty, P., Oct 1 2019, In : Human molecular genetics. 28, 19, p. 3255-3269 15 p.

Research output: Contribution to journalArticle

Tauopathies
Alzheimer Disease
Frontotemporal Dementia
Pick Disease of the Brain
Pathology

Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration (Acta Neuropathologica, (2019), 10.1007/s00401-019-02080-2)

Saijo, E., Metrick, M. A., Koga, S., Parchi, P., Litvan, I., Spina, S., Boxer, A., Rojas, J. C., Galasko, D., Kraus, A., Rossi, M., Newell, K., Zanusso, G., Grinberg, L. T., Seeley, W. W., Ghetti, B., Dickson, D. W. & Caughey, B., Jan 1 2019, (Accepted/In press) In : Acta neuropathologica.

Research output: Contribution to journalComment/debate

Open Access
Frontotemporal Lobar Degeneration
Seeds
Biomarkers
Brain

Correction to: ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD (Acta Neuropathologica, (2019), 138, 1, (49-65), 10.1007/s00401-019-01999-w)

Moore, S., Alsop, E., Lorenzini, I., Starr, A., Rabichow, B. E., Mendez, E., Levy, J. L., Burciu, C., Reiman, R., Chew, J., Belzil, V. V., Dickson, D., Robertson, J., Staats, K. A., Ichida, J. K., Petrucelli, L., Van Keuren-Jensen, K. & Sattler, R., Nov 1 2019, In : Acta neuropathologica. 138, 5, p. 883-884 2 p.

Research output: Contribution to journalComment/debate

Open Access
RNA Editing

Corrigendum: Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes

Russo, A., Scardigli, R., La Regina, F., Murray, M. E., Romano, N., Dickson, D. W., Wolozin, B., Cattaneo, A. & Ceci, M., Apr 1 2019, In : Human molecular genetics. 28, 7, 1 p.

Research output: Contribution to journalArticle

Open Access
Polyribosomes
Proteins
corrigendum
Open Access
Frontotemporal Lobar Degeneration
Neurites
Inclusion Bodies
Mutation
Blood Vessels

Dipeptide repeat (DPR) pathology in the skeletal muscle of ALS patients with C9ORF72 repeat expansion

Cykowski, M. D., Dickson, D. W., Powell, S. Z., Arumanayagam, A. S., Rivera, A. L. & Appel, S. H., Oct 1 2019, In : Acta neuropathologica. 138, 4, p. 667-670 4 p.

Research output: Contribution to journalLetter

Dipeptides
Skeletal Muscle
Pathology
Normal Pressure Hydrocephalus
Subarachnoid Space
Hydrocephalus
Atrophy
Autopsy

Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant

Carlomagno, Y., Chung, D. E. C., Yue, M., Kurti, A., Avendano, N. M., Castanedes-Casey, M., Hinkle, K. M., Jansen-West, K., Daughrity, L. M., Tong, J., Phillips, V., Rademakers, R. V., Deture, M., Fryer, J. D., Dickson, D. W., Petrucelli, L. & Cook, C., Jan 23 2019, In : Acta neuropathologica communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Dependovirus
Phosphorylation
Tauopathies
Brain
Progressive Supranuclear Palsy
3 Citations (Scopus)

Ethnoracial differences in Alzheimer's disease from the FLorida Autopsied Multi-Ethnic (FLAME)cohort

Santos, O. A., Pedraza, O. D., Lucas, J. A., Duara, R., Greig-Custo, M. T., Hanna Al-Shaikh, F. S., Liesinger, A. M., Bieniek, K. F., Hinkle, K. M., Lesser, E. R., Crook, J., Carrasquillo, M. M., Ross, O. A., Taner, N., Graff Radford, N. R., Dickson, D. W. & Murray, M. E., May 1 2019, In : Alzheimer's and Dementia. 15, 5, p. 635-643 9 p.

Research output: Contribution to journalArticle

Open Access
Hispanic Americans
Alzheimer Disease
Sclerosis
Age of Onset
Lewy Body Disease

Evaluation of Associations of Alzheimer's Disease Risk Variants that Are Highly Expressed in Microglia with Neuropathological Outcome Measures

Sakae, N., Heckman, M. G., Vargas, E. R., Carrasquillo, M. M., Murray, M. E., Kasanuki, K., Ertekin-Taner, N., Younkin, S. G. & Dickson, D. W., Jan 1 2019, In : Journal of Alzheimer's Disease. 70, 3, p. 659-666 8 p.

Research output: Contribution to journalArticle

Microglia
Alzheimer Disease
Outcome Assessment (Health Care)
Cerebral Amyloid Angiopathy
Disease Susceptibility

Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers

Dickson, D. W., Baker, M. C., Jackson, J. L., Dejesus-Hernandez, M., Finch, N. C. A., Tian, S., Heckman, M. G., Pottier, C., Gendron, T. F., Murray, M. E., Ren, Y., Reddy, J. S., Graff-Radford, N. R., Boeve, B. F., Petersen, R. C., Knopman, D. S., Josephs, K. A., Petrucelli, L., Oskarsson, B., Sheppard, J. W. & 3 others, Asmann, Y. W., Rademakers, R. & Van Blitterswijk, M., Oct 8 2019, In : Acta Neuropathologica Communications. 7, 1, 150.

Research output: Contribution to journalArticle

Open Access
Frontotemporal Lobar Degeneration
Motor Neuron Disease
Monomeric GTP-Binding Proteins
Dipeptides
GTP Phosphohydrolase Activators
68 Citations (Scopus)

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein
9 Citations (Scopus)

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H., Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Ertekin-Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Genome
Genes
Mutation

Gerstmann-Sträussler-Scheinker syndrome misdiagnosed as conversion disorder

Jiang, A. A., Longardner, K., Dickson, D. W. & Sell, R., Jan 1 2019, In : BMJ case reports. 12, 8, e229729.

Research output: Contribution to journalArticle

Conversion Disorder
Diagnostic Errors
Medical History Taking
Aspiration Pneumonia
Behavioral Symptoms
2 Citations (Scopus)

Heritability and genetic variance of dementia with Lewy bodies

for the International Parkinson's Disease Genomics Consortium, Jul 1 2019, In : Neurobiology of Disease. 127, p. 492-501 10 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Alzheimer Disease
Single Nucleotide Polymorphism
Parkinson Disease
Inborn Genetic Diseases
14 Citations (Scopus)

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity

Zhang, Y. J., Guo, L., Gonzales, P. K., Gendron, T. F., Wu, Y., Jansen-West, K., O’Raw, A. D., Pickles, S. R., Prudencio, M., Carlomagno, Y., Gachechiladze, M. A., Ludwig, C., Tian, R., Chew, J., DeTure, M., Lin, W. L., Tong, J., Daughrity, L. M., Yue, M., Song, Y. & 15 others, Andersen, J. W., Castanedes-Casey, M., Kurti, A., Datta, A., Antognetti, G., McCampbell, A., Rademakers, R., Oskarsson, B., Dickson, D. W., Kampmann, M., Ward, M. E., Fryer, J. D., Link, C. D., Shorter, J. & Petrucelli, L., Feb 15 2019, In : Science. 363, 6428, eaav2606.

Research output: Contribution to journalArticle

Double-Stranded RNA
Heterochromatin
Proline
Arginine
Proteins
4 Citations (Scopus)

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

International Frontotemporal Dementia Genomics Consortium, Jan 1 2019, In : Nature Medicine. 25, 1, p. 152-164 13 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Dementia
Genes
MicroRNAs
Pharmaceutical Databases
1 Citation (Scopus)

In vivo binding of a tau imaging probe, [ 11 C]PBB3, in patients with progressive supranuclear palsy

Endo, H., Shimada, H., Sahara, N., Ono, M., Koga, S., Kitamura, S., Niwa, F., Hirano, S., Kimura, Y., Ichise, M., Shinotoh, H., Zhang, M. R., Kuwabara, S., Dickson, D. W., Toda, T., Suhara, T. & Higuchi, M., Jan 1 2019, In : Movement Disorders.

Research output: Contribution to journalArticle

Open Access
Progressive Supranuclear Palsy
Healthy Volunteers
Pathology
Red Nucleus
benzothiazole
40 Citations (Scopus)

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

Nelson, P. T., Dickson, D. W., Trojanowski, J. Q., Jack, C. R. J., Boyle, P. A., Arfanakis, K., Rademakers, R. V., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, I. T. S., Chui, H. C., Fardo, D. W., Flanagan, M. E., Halliday, G., Hokkanen, S. R. K., Hunter, S., Jicha, G. A., Katsumata, Y., Kawas, C. H. & 15 others, Keene, C. D., Kovacs, G. G., Kukull, W. A., Levey, A. I., Makkinejad, N., Montine, T. J., Murayama, S., Murray, M. E., Nag, S., Rissman, R. A., Seeley, W. W., Sperling, R. A., White, C. L., Yu, L. & Schneider, J. A., Jun 1 2019, In : Brain : a journal of neurology. 142, 6, p. 1503-1527 25 p.

Research output: Contribution to journalArticle

Open Access
Brain Diseases
Consensus
TDP-43 Proteinopathies
Frontotemporal Lobar Degeneration
Brain
1 Citation (Scopus)

Microglia in frontotemporal lobar degeneration with progranulin or C9ORF72 mutations

Sakae, N., Roemer, S. F., Bieniek, K. F., Murray, M. E., Baker, M. C., Kasanuki, K., Graff Radford, N. R., Petrucelli, L., Van Blitterswijk, M., Rademakers, R. V. & Dickson, D. W., Jan 1 2019, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Open Access
Frontotemporal Lobar Degeneration
Microglia
Mutation
Immunohistochemistry
Apraxias

Mixed Alzheimer's and Lewy-related Pathology Can Cause Corticobasal Syndrome with Visual Hallucinations

Kasanuki, K., Koga, S., Dickson, D. W., Sato, K., Iseki, E., Ichimiya, Y. & Arai, H., Jun 15 2019, In : Internal medicine (Tokyo, Japan). 58, 12, 1 p.

Research output: Contribution to journalArticle

Open Access
Lewy Body Disease
Hallucinations
Amyloidosis
Positron-Emission Tomography
Alzheimer Disease
1 Citation (Scopus)

Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease

Lowe, V., Lundt, E. S., Albertson, S. M., Przybelski, S. A., Senjem, M. L., Parisi, J. E., Kantarci, K. M., Boeve, B. F., Jones, D. T., Knopman, D. S., Jack, C. R. J., Dickson, D. W., Petersen, R. C. & Murray, M. E., Jan 1 2019, In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Neuroimaging
Neurodegenerative Diseases
Amyloid Plaques
Alzheimer Disease
Autopsy

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy

Sakae, N., Josephs, K. A., Litvan, I., Murray, M. E., Duara, R., Uitti, R. J., Wszolek, Z. K., Graff Radford, N. R. & Dickson, D. W., Jan 1 2019, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

Open Access
Progressive Supranuclear Palsy
Frontotemporal Dementia
Pathology
Neuroglia
4 Citations (Scopus)

Ossified blood vessels in primary familial brain calcification elicit a neurotoxic astrocyte response

Zarb, Y., Weber-Stadlbauer, U., Kirschenbaum, D., Kindler, D. R., Richetto, J., Keller, D., Rademakers, R. V., Dickson, D. W., Pasch, A., Byzova, T., Nahar, K., Voigt, F. F., Helmchen, F., Boss, A., Aguzzi, A., Klohs, J. & Keller, A., Jan 1 2019, In : Brain. 142, 4, p. 885-902 18 p.

Research output: Contribution to journalArticle

Open Access
Astrocytes
Blood Vessels
Brain
Proto-Oncogene Proteins c-sis
Mutation
5 Citations (Scopus)

Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains

Josephs, K. A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Serie, A. M., Perkerson, R. B., Matchett, B. J., Jack, C. R. J., Knopman, D. S., Petersen, R. C., Parisi, J. E., Petrucelli, L., Baker, M., Rademakers, R. V., Whitwell, J. L. & Dickson, D. W., Jan 1 2019, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Amygdala
Frontotemporal Lobar Degeneration
Brain
Neuroimaging
Hippocampus

PET-detectable tau pathology correlates with long-term neuropsychiatric outcomes in patients with traumatic brain injury

Takahata, K., Kimura, Y., Sahara, N., Koga, S., Shimada, H., Ichise, M., Saito, F., Moriguchi, S., Kitamura, S., Kubota, M., Umeda, S., Niwa, F., Mizushima, J., Morimoto, Y., Funayama, M., Tabuchi, H., Bieniek, K. F., Kawamura, K., Zhang, M. R., Dickson, D. W. & 4 others, Mimura, M., Kato, M., Suhara, T. & Higuchi, M., Oct 1 2019, In : Brain : a journal of neurology. 142, 10, p. 3265-3279 15 p.

Research output: Contribution to journalArticle

Open Access
Pathology
Brain
Traumatic Brain Injury
Psychotic Disorders
Healthy Volunteers

Progressive supranuclear palsy is not associated with neurogenic orthostatic hypotension

van Gerpen, J. A., Al-Shaikh, R. H., Tipton, P. W., Wszolek, Z. K., Uitti, R. J., Ferman, T. J., Dickson, D. W., Benarroch, E. E., Singer, W., Cutsforth-Gregory, J. K., Heckman, M. G., Brushaber, D. E., Josephs, K. A., Low, P. A., Ahlskog, J. E. & Cheshire, W. P., Oct 1 2019, In : Neurology. 93, 14, p. e1339-e1347

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Orthostatic Hypotension
Adrenergic Agents
Multiple System Atrophy
Lewy Body Disease
2 Citations (Scopus)
Primary Progressive Aphasia
Agnosia
Language
Apraxias
Deafness
3 Citations (Scopus)

rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies

Croft, C. L., Cruz, P. E., Ryu, D. H., Ceballos-Diaz, C., Strang, K. H., Woody, B. M., Lin, W. L., Deture, M., Rodríguez-Lebrón, E., Dickson, D. W., Chakrabarty, P., Levites, Y., Giasson, B. I. & Golde, T. E., Mar 1 2019, In : Journal of Experimental Medicine. 216, 3, p. 539-555 17 p.

Research output: Contribution to journalArticle

Open Access
Dependovirus
Parkinson Disease
Alzheimer Disease
Pathology
Brain

Reply: LATE to the PART-y

Nelson, P. T., Dickson, D. W., Trojanowski, J. Q., Jack, C. R., Boyle, P. A., Arfanakis, K., Rademakers, R., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, I. T. S., Fardo, D. W., Flanagan, M. E., Halliday, G., Hunter, S., Jicha, G. A., Katsumata, Y., Kawas, C. H., Dirk Keene, C., Kovacs, G. G. & 10 others, Kukull, W. A., Levey, A. I., Makkinejad, N., Montine, T. J., Murray, M. E., Nag, S., Seeley, W. W., Sperling, R. A., White, C. L. & Schneider, J. A., Sep 1 2019, In : Brain. 142, 9, p. 1-3 3 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression

Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., Dickson, D. W., Kanekiyo, T. & Bu, G. D., Apr 1 2019, In : Brain : a journal of neurology. 142, 4, p. 1077-1092 16 p.

Research output: Contribution to journalArticle

Tight Junction Proteins
Disease Progression
Alzheimer Disease
Amyloid
Brain

Selective Vulnerability of the Nucleus Basalis of Meynert among Neuropathologic Subtypes of Alzheimer Disease

Hanna Al-Shaikh, F. S., Duara, R., Crook, J. E., Lesser, E. R., Schaeverbeke, J., Hinkle, K. M., Ross, O. A., Ertekin-Taner, N., Pedraza, O., Dickson, D. W., Graff-Radford, N. R. & Murray, M. E., Jan 1 2019, (Accepted/In press) In : JAMA neurology.

Research output: Contribution to journalArticle

Open Access
Basal Nucleus of Meynert
Alzheimer Disease
Neurofibrillary Tangles
Cholinergic Agents
Demography
13 Citations (Scopus)

Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy

Ali, F., Martin, P. R., Botha, H., Ahlskog, J. E., Bower, J. H., Masumoto, J. Y., Maraganore, D., Hassan, A., Eggers, S. D., Boeve, B. F., Knopman, D. S., Drubach, D., Petersen, R. C., Dunkley, E. D., Van Gerpen, J. A., Uitti, R., Whitwell, J. L., Dickson, D. W. & Josephs, K. A., Jan 1 2019, In : Movement Disorders.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Sensitivity and Specificity
Phenotype
Parkinsonian Disorders
Neurodegenerative Diseases

Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples

Seidler, P. M., Boyer, D. R., Murray, K. A., Yang, T. P., Bentzel, M., Sawaya, M. R., Rosenberg, G., Cascio, D., Williams, C. K., Newell, K. L., Ghetti, B., DeTure, M. A., Dickson, D. W., Vinters, H. V. & Eisenberg, D. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 44, p. 16451-16464 14 p.

Research output: Contribution to journalArticle

Tauopathies
Prions
Polymorphism
Brain
Alzheimer Disease