Claudia F Lucchinetti, MD

  • 32903 Citations
  • 81 Scopus h-Index
1976 …2019
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Research Output 1988 2019

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2019

Exercise and metformin counteract altered mitochondrial function in the insulinresistant brain

Ruegsegger, G. N., Vanderboom, P. M., Dasari, S., Klaus, K. A., Kabiraj, P., McCarthy, C. B., Lucchinetti, C. F. & Nair, K. S., Sep 19 2019, In : JCI Insight. 4, 18, e130681.

Research output: Contribution to journalArticle

Open Access
Metformin
Insulin Resistance
Insulin Receptor
Brain
Insulin

Phosphodiesterase 10A IgG: A novel biomarker of paraneoplastic neurologic autoimmunity

Zekeridou, A., Kryzer, T., Guo, Y., Hassan, A., Lennon, V. A., Lucchinetti, C. F., Pittock, S. J. & McKeon, A., Aug 20 2019, In : Neurology. 93, 8, p. e815-e822

Research output: Contribution to journalArticle

Open Access
Phosphoric Diester Hydrolases
Autoimmunity
Nervous System
Immunoglobulin G
Biomarkers
1 Citation (Scopus)

Using germline variants to estimate glioma and subtype risks

Eckel-Passow, J. E., Decker, P. A., Kosel, M. L., Kollmeyer, T. M., Molinaro, A. M., Rice, T., Caron, A. A., Drucker, K. L., Praska, C. E., Pekmezci, M., Hansen, H. M., Mccoy, L. S., Bracci, P. M., Erickson, B. J., Lucchinetti, C. F., Wiemels, J. L., Wiencke, J. K., Bondy, M. L., Melin, B., Burns, T. & 4 others, Giannini, C., Lachance, D. H., Wrensch, M. R. & Jenkins, R. B., Mar 18 2019, In : Neuro-oncology. 21, 4, p. 451-461 11 p.

Research output: Contribution to journalArticle

Glioma
Isocitrate Dehydrogenase
Single Nucleotide Polymorphism
Logistic Models
Mutation
2018
20 Citations (Scopus)

Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Autoantibody Status Predict Outcome of Recurrent Optic Neuritis

Jitprapaikulsan, J., Chen, J., Flanagan, E., Tobin, W. O., Fryer, J. P., Weinshenker, B. G., McKeon, A., Lennon, V. A., Leavitt, J. A., Tillema, J-M., Lucchinetti, C. F., Keegan, B. M., Kantarci, O. H., Khanna, C., Jenkins, S. M., Spears, G. M., Sagan, J. & Pittock, S. J., Jan 1 2018, (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Aquaporin 4
Optic Neuritis
Autoantibodies
Immunoglobulin G
34 Citations (Scopus)

Association of MOG-IgG Serostatus with Relapse after Acute Disseminated Encephalomyelitis and Proposed Diagnostic Criteria for MOG-IgG-Associated Disorders

López-Chiriboga, A. S., Majed, M., Fryer, J., Dubey, D., McKeon, A., Flanagan, E., Jitprapaikulsan, J., Kothapalli, N., Tillema, J-M., Chen, J., Weinshenker, B. G., Wingerchuk, D. M., Sagen, J., Gadoth, A., Lennon, V. A., Keegan, B. M., Lucchinetti, C. F. & Pittock, S. J., Nov 1 2018, In : JAMA Neurology. 75, 11, p. 1355-1363 9 p.

Research output: Contribution to journalArticle

Acute Disseminated Encephalomyelitis
Immunoglobulin G
Recurrence
Immunotherapy
Myelin-Oligodendrocyte Glycoprotein
16 Citations (Scopus)

Clinical, Radiologic, and Prognostic Features of Myelitis Associated with Myelin Oligodendrocyte Glycoprotein Autoantibody

Dubey, D., Pittock, S. J., Krecke, K. N., Morris, P. P., Sechi, E., Zalewski, N. L., Weinshenker, B. G., Shosha, E., Lucchinetti, C. F., Fryer, J. P., Lopez-Chiriboga, A. S., Chen, J., Jitprapaikulsan, J., McKeon, A., Gadoth, A., Keegan, B. M., Tillema, J-M., Naddaf, E., Patterson, M. C., Messacar, K. & 2 others, Tyler, K. L. & Flanagan, E., Jan 1 2018, (Accepted/In press) In : JAMA Neurology.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Myelitis
Autoantibodies
Immunoglobulin G
Aquaporin 4
1 Citation (Scopus)

Dark rims: Novel sequence enhances diagnostic specificity in multiple sclerosis

Tillema, J-M., Weigand, S. D., Dayan, M., Shu, Y., Kantarci, O. H., Lucchinetti, C. F. & Port, J. D., Jun 1 2018, In : American Journal of Neuroradiology. 39, 6, p. 1052-1058 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Sequence Inversion
Control Groups
Granulocyte-Macrophage Colony-Stimulating Factor
Diagnostic Errors
14 Citations (Scopus)

Differences in the reponses to apheresis therapy of patients with 3 histopathologically classified immunopathological patterns of multiple sclerosis

Stork, L., Ellenberger, D., Beißbarth, T., Friede, T., Lucchinetti, C. F., Brück, W. & Metz, I., Apr 1 2018, In : JAMA Neurology. 75, 4, p. 428-435 8 p.

Research output: Contribution to journalArticle

Blood Component Removal
Multiple Sclerosis
Therapeutics
Demyelinating Diseases
Plasma Exchange
25 Citations (Scopus)

Myelin Oligodendrocyte Glycoprotein Antibody–Positive Optic Neuritis: Clinical Characteristics, Radiologic Clues, and Outcome

Chen, J., Flanagan, E., Jitprapaikulsan, J., López-Chiriboga, A. S. S., Fryer, J. P., Leavitt, J. A., Weinshenker, B. G., McKeon, A., Tillema, J-M., Lennon, V. A., Tobin, W. O., Keegan, B. M., Lucchinetti, C. F., Kantarci, O. H., McClelland, C. M., Lee, M. S., Bennett, J. L., Pelak, V. S., Chen, Y., VanStavern, G. & 7 others, Adesina, O. O. O., Eggenberger, E. R., Acierno, M. D., Wingerchuk, D. M., Brazis, P. W., Sagen, J. & Pittock, S. J., Nov 1 2018, In : American Journal of Ophthalmology. 195, p. 8-15 8 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Optic Neuritis
Immunoglobulin G
Neurologic Manifestations
Visual Acuity
1 Citation (Scopus)

Neuromyelitis Optica and Herpes Simplex Virus 2

Vanessa Marin Collazo, I., Howe, C. L., Lucchinetti, C. F. & Tobin, W., Jan 1 2018, In : Neurologist. 23, 3, p. 92-93 2 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Human Herpesvirus 2
Antibodies
Virus Diseases
4 Citations (Scopus)

Paraneoplastic neuronal intermediate filament autoimmunity

Basal, E., Zalewski, N., Kryzer, T. J., Hinson, S. R., Guo, Y., Dubey, D., Benarroch, E. E., Lucchinetti, C. F., Pittock, S. J., Lennon, V. A. & McKeon, A., Oct 30 2018, In : Neurology. 91, 18, p. e1677-e1689

Research output: Contribution to journalArticle

Intermediate Filaments
Autoimmunity
Immunoglobulin G
Light
Fluorescent Antibody Technique
2 Citations (Scopus)
Population
Medical Record Linkage
Mitoxantrone
Recurrence
Injections
2017
2 Citations (Scopus)

Clinical–radiological–pathological spectrum of central nervous system–idiopathic inflammatory demyelinating disease in the elderly

Tobin, W., Costanzi, C., Guo, Y., Parisi, J. E., Weigand, S. D. & Lucchinetti, C. F., Jan 1 2017, In : Multiple Sclerosis Journal. 23, 9, p. 1204-1213 10 p.

Research output: Contribution to journalArticle

Demyelinating Diseases
Multiple Sclerosis
Acute Disseminated Encephalomyelitis
Neuromyelitis Optica
Central Nervous System Diseases
40 Citations (Scopus)

Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)

Tobin, W. O., Guo, Y., Krecke, K. N., Parisi, J. E., Lucchinetti, C. F., Pittock, S. J., Mandrekar, J., Dubey, D., Debruyne, J. & Keegan, B. M., Sep 1 2017, In : Brain. 140, 9, p. 2415-2425 11 p.

Research output: Contribution to journalArticle

Steroids
Inflammation
Adrenal Cortex Hormones
Gadolinium
Age of Onset
1 Citation (Scopus)

In vivo detection of connectivity between cortical and white matter lesions in early MS

Tillema, J-M., Weigand, S. D., Mandrekar, J., Shu, Y., Lucchinetti, C. F., Pirko, I. & Port, J. D., Jun 1 2017, In : Multiple Sclerosis. 23, 7, p. 973-981 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Diffusion Tensor Imaging
White Matter
Magnetic Resonance Imaging
Relapsing-Remitting Multiple Sclerosis
12 Citations (Scopus)

Pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica

Guo, Y., Weigand, S. D., Popescu, B. F., Lennon, V. A., Parisi, J. E., Pittock, S. J., Parks, N. E., Clardy, S. L., Howe, C. L. & Lucchinetti, C. F., Feb 9 2017, (Accepted/In press) In : Acta Neuropathologica. p. 1-16 16 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Aquaporin 4
Cerebrospinal Fluid
Pathology
Choroid Plexus
24 Citations (Scopus)

Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions

Popescu, B. F., Frischer, J. M., Webb, S. M., Tham, M., Adiele, R. C., Robinson, C. A., Fitz-Gibbon, P. D., Weigand, S. D., Metz, I., Nehzati, S., George, G. N., Pickering, I. J., Brück, W., Hametner, S., Lassmann, H., Parisi, J. E., Yong, G. & Lucchinetti, C. F., Mar 22 2017, (Accepted/In press) In : Acta Neuropathologica. p. 1-20 20 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Zinc
Iron
Central Nervous System
Metals
2 Citations (Scopus)
Purkinje Cells
Anti-Idiotypic Antibodies
Adenocarcinoma
2016
79 Citations (Scopus)

Acute disseminated encephalomyelitis: Updates on an inflammatory CNS syndrome

Pohl, D., Alper, G., Van Haren, K., Kornberg, A. J., Lucchinetti, C. F., Tenembaum, S. & Belman, A. L., Aug 30 2016, In : Neurology. 87, 9, p. S38-S45

Research output: Contribution to journalArticle

Acute Disseminated Encephalomyelitis
Multiple Sclerosis
Myelin-Oligodendrocyte Glycoprotein
Oligoclonal Bands
Encephalomyelitis
74 Citations (Scopus)

Epidemiology of aquaporin-4 autoimmunity and neuromyelitis optica spectrum

Flanagan, E., Cabre, P., Weinshenker, B. G., St. Sauver, J., Jacobson, D. J., Majed, M., Lennon, V. A., Lucchinetti, C. F., McKeon, A., Matiello, M., Kale, N., Wingerchuk, D. M., Mandrekar, J., Sagen, J. A., Fryer, J. P., Robinson, A. B. & Pittock, S. J., May 1 2016, In : Annals of Neurology. 79, 5, p. 775-783 9 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Autoimmunity
Martinique
Epidemiology
18 Citations (Scopus)

LRP1 expression in microglia is protective during CNS autoimmunity

Chuang, T. Y., Guo, Y., Seki, S. M., Rosen, A. M., Johanson, D. M., Mandell, J. W., Lucchinetti, C. F. & Gaultier, A., Jul 11 2016, In : Acta neuropathologica communications. 4, 1, 1 p.

Research output: Contribution to journalArticle

Lipoprotein Receptors
Microglia
Autoimmunity
Multiple Sclerosis
Myeloid Cells
21 Citations (Scopus)

Meningeal mast cell-T cell crosstalk regulates T cell encephalitogenicity

Russi, A. E., Walker-Caulfield, M. E., Guo, Y., Lucchinetti, C. F. & Brown, M. A., Sep 1 2016, In : Journal of Autoimmunity. 73, p. 100-110 11 p.

Research output: Contribution to journalArticle

Mast Cells
Granulocyte-Macrophage Colony-Stimulating Factor
Helper-Inducer T-Lymphocytes
Meninges
T-Lymphocytes
6 Citations (Scopus)

Multiple sclerosis masquerading as Alzheimer-type dementia: Clinical, radiological and pathological findings

Tobin, W., Popescu, B. F., Lowe, V., Pirko, I., Parisi, J. E., Kantarci, K. M., Fields, J. A., Bruns, M. B., Boeve, B. F. & Lucchinetti, C. F., Apr 1 2016, In : Multiple Sclerosis. 22, 5, p. 698-704 7 p.

Research output: Contribution to journalArticle

Demyelinating Diseases
Multiple Sclerosis
Autopsy
Alzheimer Disease
Myelin Sheath
8 Citations (Scopus)

Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells

Wang, Y., Cao, Y., Mangalam, A. K., Guo, Y., LaFrance-Corey, R. G., Gamez, J. D., Atanga, P. A., Clarkson, B. D., Zhang, Y., Wang, E., Angom, R. S., Dutta, K., Ji, B. D., Pirko, I., Lucchinetti, C. F., Howe, C. L. & Mukhopadhyay, D., 2016, In : Journal of Cell Science. 129, 20, p. 3911-3921 11 p.

Research output: Contribution to journalArticle

Neuropilin-1
Interferons
Endothelial Cells
Blood-Brain Barrier
Brain
17 Citations (Scopus)

Relapses in multiple sclerosis: Relationship to disability

Goodin, D. S., Reder, A. T., Bermel, R. A., Cutter, G. R., Fox, R. J., John, G. R., Lublin, F. D., Lucchinetti, C. F., Miller, A. E., Pelletier, D., Racke, M. K., Trapp, B. D., Vartanian, T. & Waubant, E., Mar 1 2016, In : Multiple Sclerosis and Related Disorders. 6, p. 10-20 11 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Recurrence
Central Nervous System Diseases
Outcome Assessment (Health Care)
Clinical Trials
16 Citations (Scopus)

Ring-enhancing spinal cord lesions in neuromyelitis optica spectrum disorders

Zalewski, N. L., Morris, P. P., Weinshenker, B. G., Lucchinetti, C. F., Guo, Y., Pittock, S. J., Krecke, K. N., Kaufmann, T. J., Wingerchuk, D. M., Kumar, N. & Flanagan, E., Dec 2 2016, (Accepted/In press) In : Journal of Neurology, Neurosurgery and Psychiatry.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Myelitis
Spinal Cord
Aquaporin 4
Spinal Cord Diseases
2015
131 Citations (Scopus)

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

Frischer, J. M., Weigand, S. D., Guo, Y., Kale, N., Parisi, J. E., Pirko, I., Mandrekar, J., Bramow, S., Metz, I., Brück, W., Lassmann, H. & Lucchinetti, C. F., Nov 1 2015, In : Annals of Neurology. 78, 5, p. 710-721 12 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Chronic Progressive Multiple Sclerosis
Pathology
White Matter
Relapsing-Remitting Multiple Sclerosis
5 Citations (Scopus)

Corrigendum: Multiple sclerosis - A quiet revolution

Ransohoff, R. M., Hafler, D. A. & Lucchinetti, C. F., May 11 2015, In : Nature Reviews Neurology. 11, 5, p. 246 1 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Extensive acute axonal damage in pediatric multiple sclerosis lesions

Pfeifenbring, S., Bunyan, R. F., Metz, I., Röver, C., Huppke, P., Gärtner, J., Lucchinetti, C. F. & Brück, W., Apr 1 2015, In : Annals of Neurology. 77, 4, p. 655-667 13 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Pediatrics
Amyloid beta-Protein Precursor
Autopsy
Biopsy
177 Citations (Scopus)

Multiple sclerosis - A quiet revolution

Ransohoff, R. M., Hafler, D. A. & Lucchinetti, C. F., Mar 14 2015, In : Nature Reviews Neurology. 11, 3, p. 134-142 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Disease Susceptibility
Computational Biology
Neuroimaging
Therapeutics
56 Citations (Scopus)
Channelopathies
Aquaporin 4
Neuromyelitis Optica
Brain
Immunoglobulin G
11 Citations (Scopus)

NFΚB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG

Walker-Caulfield, M. E., Guo, Y., Johnson, R. K., McCarthy, C. B., Fitz-Gibbon, P. D., Lucchinetti, C. F. & Howe, C. L., Sep 30 2015, In : Journal of Neuroinflammation. 12, 1, 185.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Immunoglobulin G
Astrocytes
Aquaporin 4
Aquaporins
32 Citations (Scopus)

Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis

Novotna, M., Paz Soldán, M. M., Zeid, N. A., Kale, N., Tutuncu, M., Crusan, D. J., Atkinson, E. J., Siva, A., Keegan, B. M., Pirko, I., Pittock, S. J., Lucchinetti, C. F., Noseworthy, J. H., Weinshenker, B. G., Rodriguez, M. & Kantarci, O. H., Aug 25 2015, In : Neurology. 85, 8, p. 722-729 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Recurrence
Chronic Progressive Multiple Sclerosis
Population
Relapsing-Remitting Multiple Sclerosis
42 Citations (Scopus)

Relapses and disability accumulation in progressive multiple sclerosis

Soldán, M. M. P., Novotna, M., Zeid, N. A., Kale, N., Tutuncu, M., Crusan, D. J., Atkinson, E. J., Siva, A., Keegan, B. M., Pirko, I., Pittock, S. J., Lucchinetti, C. F., Weinshenker, B. G., Rodriguez, M. & Kantarci, O. H., 2015, In : Neurology. 84, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Chronic Progressive Multiple Sclerosis
Recurrence
Immunomodulation
Confidence Intervals
98 Citations (Scopus)

Short myelitis lesions in aquaporin-4-IgG-positive neuromyelitis optica spectrum disorders

Flanagan, E., Weinshenker, B. G., Krecke, K. N., Lennon, V. A., Lucchinetti, C. F., McKeon, A., Wingerchuk, D. M., Shuster, E. A., Jiao, Y., Horta, E. S. & Pittock, S. J., Jan 1 2015, In : JAMA Neurology. 72, 1, p. 81-87 7 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Myelitis
Immunoglobulin G
Transverse Myelitis
2014
44 Citations (Scopus)

AQP4 autoantibody assay performance in clinical laboratory service

Fryer, J. P., Lennon, V. A., Pittock, S. J., Jenkins, S. M., Fallier-Becker, P., Clardy, S. L., Horta, E., Jedynak, E. A., Lucchinetti, C. F., Shuster, E. A., Weinshenker, B. G., Wingerchuk, D. M. & McKeon, A. B., Apr 24 2014, In : Neurology: Neuroimmunology and NeuroInflammation. 1, 1, 11.

Research output: Contribution to journalArticle

Clinical Laboratory Services
Aquaporin 4
Autoantibodies
Flow Cytometry
Neuromyelitis Optica
38 Citations (Scopus)

Aquaporin 4 IgG serostatus and outcome in recurrent longitudinally extensive transverse myelitis

Jiao, Y., Fryer, J. P., Lennon, V. A., McKeon, A. B., Jenkins, S. M., Smith, C. Y., Quek, A. M. L., Weinshenker, B. G., Wingerchuk, D. M., Shuster, E. A., Lucchinetti, C. F. & Pittock, S. J., 2014, In : JAMA Neurology. 71, 1, p. 48-54 7 p.

Research output: Contribution to journalArticle

Transverse Myelitis
Aquaporin 4
Immunoglobulin G
Neuromyelitis Optica
Indirect Fluorescent Antibody Technique
38 Citations (Scopus)

Autoimmune aquaporin-4 myopathy in neuromyelitis optica spectrum

Guo, Y., Lennon, V. A., Bogdan, B. F., Grouse, C. K., Topel, J., Milone, M., Lassmann, H., Parisi, J. E., Pittock, S. J., Stefoski, D., Balabanov, R. & Lucchinetti, C. F., 2014, In : JAMA Neurology. 71, 8, p. 1025-1029 5 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Muscular Diseases
Immunoglobulin G
Muscles
12 Citations (Scopus)

Clinical/scientific notes

Clardy, S. L., Lucchinetti, C. F., Krecke, K. N., Lennon, V. A., O'Toole, O., Weinshenker, B. G., Boyd, C. D., Krieger, S., McGraw, C., Guo, Y. & Pittock, S. J., May 20 2014, In : Neurology. 82, 20, p. 1841-1843 3 p.

Research output: Contribution to journalArticle

Hydrocephalus
26 Citations (Scopus)

Diagnostic utility of aquaporin-4 in the analysis of active demyelinating lesions

Popescu, B. F. G., Guo, Y., Jentoft, M. E., Parisi, J. E., Lennon, V. A., Pittock, S. J., Weinshenker, B. G., Wingerchuk, D. M., Giannini, C., Metz, I., Brück, W., Shuster, E. A., Carter, J., Boyd, C. D., Clardy, S. L., Cohen, B. A. & Lucchinetti, C. F., 2014, In : Neurology. 84, 2, p. 148-158 11 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Biopsy
Immunoglobulin G
Astrocytes
96 Citations (Scopus)

DPPX potassium channel antibody: Frequency, clinical accompaniments, and outcomes in 20 patients

Tobin, W., Lennon, V. A., Komorowski, L., Probst, C., Clardy, S. L., Aksamit, A. J., Appendino, J. P., Lucchinetti, C. F., Matsumoto, J. Y., Pittock, S. J., Sandroni, P., Tippmann-Peikert, M., Wirrell, E. C. & McKeon, A. B., Nov 1 2014, In : Neurology. 83, 20, p. 1797-1803 7 p.

Research output: Contribution to journalArticle

Potassium Channels
Antibodies
Immunoglobulin G
Stiff-Person Syndrome
Nervous System Diseases
12 Citations (Scopus)

Early and widespread injury of astrocytes in the absence of demyelination in acute haemorrhagic leukoencephalitis

Robinson, C. A., Adiele, R. C., Tham, M., Lucchinetti, C. F. & Popescu, B. F. G. H., 2014, In : Acta neuropathologica communications. 2, p. 52 1 p.

Research output: Contribution to journalArticle

Acute Hemorrhagic Leukoencephalitis
Demyelinating Diseases
Astrocytes
Wounds and Injuries
Edema
56 Citations (Scopus)

Investigation of the KIR4.1 potassium channel as a putative antigen in patients with multiple sclerosis: A comparative study

Brickshawana, A., Hinson, S. R., Romero, M. F., Lucchinetti, C. F., Guo, Y., Buttmann, M., McKeon, A. B., Pittock, S. J., Chang, M. H., Chen, A. P., Kryzer, T. J., Fryer, J. P., Jenkins, S. M., Cabre, P. & Lennon, V. A., 2014, In : The Lancet Neurology. 13, 8, p. 795-806 12 p.

Research output: Contribution to journalArticle

Potassium Channels
Multiple Sclerosis
Antigens
Immunoglobulin G
Serum
25 Citations (Scopus)

Longitudinally extensive transverse myelitis

Tobin, W., Weinshenker, B. G. & Lucchinetti, C. F., 2014, In : Current Opinion in Neurology. 27, 3, p. 279-289 11 p.

Research output: Contribution to journalArticle

Transverse Myelitis
Neuromyelitis Optica
Immunoglobulin G
Spinal Cord Diseases
Flow Cytometry
28 Citations (Scopus)

Neuromyelitis optica IgG stimulates an immunological response in rat astrocyte cultures

Howe, C. L., Kaptzan, T., Magaña, S. M., Ayers-Ringler, J. R., Lafrance-Corey, R. G. & Lucchinetti, C. F., 2014, In : GLIA. 62, 5, p. 692-708 17 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Astrocytes
Immunoglobulin G
Aquaporin 4
Serum
27 Citations (Scopus)

Paraneoplastic neuromyelitis optica spectrum disorder associated with metastatic carcinoid expressing aquaporin-4

Figueroa, M., Guo, Y., Tselis, A., Pittock, S. J., Lennon, V. A., Lucchinetti, C. F. & Lisak, R. P., 2014, In : JAMA Neurology. 71, 4, p. 495-498 4 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Carcinoid Tumor
Neuroendocrine Tumors
Paresthesia
59 Citations (Scopus)

Pathologic heterogeneity persists in early active multiple sclerosis lesions

Metz, I., Weigand, S. D., Popescu, B. F. G., Frischer, J. M., Parisi, J. E., Guo, Y., Lassmann, H., Brück, W. & Lucchinetti, C. F., 2014, In : Annals of Neurology. 75, 5, p. 728-738 11 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Demyelinating Diseases
Biopsy
Autopsy
Central Nervous System
120 Citations (Scopus)

The pathology of an autoimmune astrocytopathy: Lessons learned from neuromyelitis optica

Lucchinetti, C. F., Guo, Y., Popescu, B. F. G., Fujihara, K., Itoyama, Y. & Misu, T., Jan 2014, In : Brain Pathology. 24, 1, p. 83-97 15 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Pathology
Aquaporin 4
Multiple Sclerosis
Glial Fibrillary Acidic Protein
2013
213 Citations (Scopus)
Aquaporin 4
Neuromyelitis Optica
Immunoglobulin G
Therapeutics
eculizumab
19 Citations (Scopus)

Evidence of aquaporin involvement in human central pontine myelinolysis

Popescu, B. F. G., Bunyan, R. F., Guo, Y., Parisi, J. E., Lennon, V. A. & Lucchinetti, C. F., 2013, In : Acta neuropathologica communications. 1, 1, p. 40 1 p.

Research output: Contribution to journalArticle

Central Pontine Myelinolysis
Aquaporin 1
Aquaporin 4
Aquaporins
Astrocytes