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Claudia F Lucchinetti, MD

  • 32816 Citations
  • 81 Scopus h-Index
1976 …2019
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  • 14 Similar Profiles
Multiple Sclerosis Medicine & Life Sciences
Neuromyelitis Optica Medicine & Life Sciences
Demyelinating Diseases Medicine & Life Sciences
Aquaporin 4 Medicine & Life Sciences
Immunoglobulin G Medicine & Life Sciences
Pathology Medicine & Life Sciences
Autoantibodies Medicine & Life Sciences
Brain Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1976 2014

Genetic Determinants of Pathologic Heterogeneity in MS

Lucchinetti, C. F.

National Institutes of Health

7/1/04 → 4/30/14

Project: Research project

Pathology
Multiple Sclerosis
Inflammation
Demyelinating Diseases
Phenotype

GENERAL CLINICAL RESEARCH CENTER

Levine, J. A., Lennon, R., Richardson, R., Calvo, M., Czaja, A., Noseworthy, J., Brubaker, R., Dickson, E. R., Coulie, B., Sheedy, P., Gami, A., Miller, T. B., Boerwinkle, E., Vassallo, M., Hodgson, S., Steadman, C., Kelly, K., Velosa, J., Fleming, C., Benarroch, E., Kim, C., Jett, J., Behrenbeck, T., Goronzy, J., Kennedy, F., Sing, C., Campbell, P. J., Flickinger, A., Rumberger, J., Haymond, M. W., Beers, T., Eastell, R. M., Homan, M., Gerich, J., Silverstein, M., Coppack, S., Wilson, D., Kottke, B., Consoli, A., Ebeling, P., Krom, R., Klein, K., Malagelada, J., Holmes, D., Burritt, M., Litzow, M., Griggs, R., Lindor, K., Gleich, G., Chao, E., Ahlskog, J. E., Butler, P., Li, J., Phillips, S., Khandheria, B. K., Simon, P., Pemberton, J., Rubin, J., Prather, C., Nguyen, T., Sinaki, M., Gorman, C., Gay, P., Burch, P., Sandborn, W., Dumesic, D., Fitzpatrick, L., Ames, M., Mazlumzadeh, M., Nehra, V., Beck, K., Yunginger, J. W., Service, F. J., Talley, N., Murray, J., Adjei, A., Riggs, B. L., Schwenk, W. F., Harper, C., Brennan, M., Sheedy, P., Mauras, N., Vittone, J., Dietz, N., Anderson, P., Darmaun, D., Paya, C., Morgenstern, B., Dotson, R., Lacy, M., Cameron, A., Nielsen, S., Minson, C., Halliwill, J. R., Lacy, M., Thompson, W., Canzanello, V., Jean, F., Phy, J., Rihal, C., Maraganore, D. M., Charkoudian, N., Dietz, N., Jacobsen, S., Lieber, M., Skoog, S., Martin, D., Frantz, R., Thornhill, A., Kim, H., Caples, S. M., Petersen, R. C., Hubmayr, R. D., Allison, T. G., Windebank, A. J., Reid, J. M., Hurt, R. D., Torres, V., Hartmann, L. C., Mulvagh, S. L., Poland, G. A., Schwartz, G. L., Ingle, J. N., Olson, L. J., Tefferi, A., Weinshenker, B. G., Witzig, T. E., Butterfield, J. H., Wiesner, R. H., Buckner, J. C., Textor, S. C., Khosla, S., Matteson, E. L., Low, P. A., Milliner, D. S., Kamath, P. S., Melton, III, L. J. I., Charlton, M. R., Smallridge, R. C., Jensen, M. D., Joyner, M. J., Jatoi, A., Warner, D. O., Nair, K. S., Bharucha, A. E., Miles, J. M., Turner, S. T., Krowka, M. J., Erlichman, C., Johnson, B. D., Rizza, R. A., Kullo, I. J., Chen, H. H., Jacobson, R. M., Torres, V., Alberts, S. R., Dispenzieri, A., Alberts, S. R., Limburg, P. J., Lucchinetti, C. F., Poland, G. A., Basu, A., Veldhuis, J. D., Torres, V., Fervenza, F. C., Markovic, S. N., Galanis, E., Gores, G. J., Buckner, J. C., Sandroni, P., Specks, U., Khosla, S., Kullo, I. J., Olson, L. J., Basu, R., Kay, N. E., Kaufman, K. R., Somers, V., Low, P. A., Chen, H. H., Milliner, D. S., Schwartz, G. L., Vincent, A., Ansell, S. M., Pardi, D. S., Ebbert, J. O., O'Connell, P., Silbert, P., Firek, A., van Dellen, R., Berseth, C., Kirk, E., Klein, L., Kellow, J., Spittell, P., Nelson, T., Luthra, H., Ryan, R., Thistle, J. L., Carson, C., Hagler, D., O'Brien, T., Heath, H., O'Keefe, S., Cook, D., Bowles, C., Rakela, J., Frigas, E., Zimmerman, R., Warner, M., Hammer, H., Beeler, G., Rakela, J., Nichols, W., Foote, R., Thistle, J., McMahon, M., Hatmond, M., Muenter, M., Rodehaffer, R., Cortese, D. A., So, E., Zachariah, P., Badimon, J., Lloyd, M., O'Connell, E., Hsu, J., Krahn, L., Reed, C. E., Grptz, R., Hartman, L., Bowie, E., Li, T., Zimmerman, R., McEvoy, K., Quinlan, J. C., Cameron, G. S., Larusso, N., Field, C., Schaff, H., Sachs, M., Tiegs, R., Smith, H., Colgan, J., Argueta, R., Larsson, L., Pfenning, M., Letendre, L., Muenter, M. D., Moertel, C., Zimmerman, B. R., Smith, C., Reed, C., Scott, R., Rehder, K. A. I., Ory, S., Maddox, D. E., Nishimura, R., Khanderia, B., Cheesbro, J., Baratz, K., Loeb, D., Rodeheffer, R., Connolly, D., Heath, H., Szurszewski, J., Humes, R., Debolt, M., Zimmerman, D., Chesebro, J., Schirger, A., Callaway, C., Chesebro, J. H., Bergstrom, L., Mock, M., Kalthoff, L., McCannal, C., Hayes, D., Shepard, J., Sheridan, P., Edmonson, J., Tiegs, R. D., Chesebro, J., Beckett, V., Lin, S., Matsumoto, J., Thistle, J., Lufkin, E., Larusso, N., Miser, J., Rodeheffer, R., Kovach, J., Wooten, R., Ruegemer, J., Katz, K., Krayer, S., Yunginger, J., Strong, C., vandyke, R., Schneider, T., Jacobs, L., Fick, A., Miedema, B., Frye, R. L., Margulies, K., Perry, R., Martin, W., Marcoux, J., Degroen, P., Di Magno, E., Gross, J. B., Cortese, D., Miser, J., Reed, C. E., Proana, M., Weinshilboum, R., Prendergast, F., Hunt, L., Mock, M., Gross, J., Miller, W., Ahlquist, D., Cooper, L., Arndt, C., Gilchrist, G., Williams, A., Dimagno, E., Kopecky, S., Wang, K., Zimmerman, B., Burnett, J., French, A., Bengtson, K., Hurley, D., Sarano, M., Rodeheffer, R. J., Ahlquist, D., Oconnell, M., Burnett, J., Sim, F., Melton, J., Zimmerman, D., Meissner, I., Rummans, T., Perez, E., Arndt, C., Cooper, L., Dupras, D., McPhail, I., Kopecky, S., Reid, K., Reid, K., Bunch, T., Rosado, B., Pruthi, R., Meissner, I., Eghbali-Fatourechi, G., Benrud-Larson, L., Bruce-Neeley, B., Sletteen, [. V., Barrette, B., Saito Loftus, Y., Kirmani, S., Heit, J., Kotagal, S., Arndt, C., Morrey, B., Enriquez-Sarano, M., Chareonthaitawee, P., Dahm, D., Port, J. D., Pitot, H., Foxx-Orenstein, A., Lanningham-Foster, L., Tsang, T. S. M., Eghbali Fatourechi, G., Nyberg, S., Buttar, N., Sarkaria, J., Romero, Y., Dyck, P. J., Kumar, R., Pitot, H. C., Vickers Douglas, K. S., Shah, V., Gonenne, J., Masuki, S., Sundt, T., Camilleri, M., Young, W., Kottke, T., Jones, K., Bourne, W., Berger, P., Porayko, M., Greipp, P., Vockley, G., Schwenk, F., Hensrud, D., Goldberg, R., O'Connell, P., Silbert, P., Firek, A., van Dellen, R., Berseth, C., Kirk, E., Klein, L., Kellow, J., Spittell, P., Nelson, T., Luthra, H., Ryan, R., Richardson, R., Thistle, J. L., Carson, C., Hagler, D., O'Brien, T., Kim, C., Heath, H., O'Keefe, S., Cook, D., Behrenbeck, T., Kennedy, F., Campbell, P. J., Young, W., Bowles, C., Rakela, J., Czaja, A., Frigas, E., Haymond, M. W., Zimmerman, R., Silverstein, M., Warner, M., Hammer, H., Beeler, G., Coppack, S., Rakela, J., Nichols, W., Foote, R., Thistle, J., Klein, K., McMahon, M., Hatmond, M., Muenter, M., Rodehaffer, R., Cortese, D. A., So, E., Zachariah, P., Badimon, J., Lloyd, M., O'Connell, E., Miller, T. B., Hsu, J., Krahn, L., Reed, C. E., Grptz, R., Kelly, K., Hartman, L., Bowie, E., Velosa, J., Li, T., Zimmerman, R., McEvoy, K., Quinlan, J. C., Sing, C., Cameron, G. S., Larusso, N., Field, C., Schaff, H., Wilson, D., Consoli, A., Sachs, M., Tiegs, R., Krom, R., Smith, H., Colgan, J., Argueta, R., Larsson, L., Pfenning, M., Letendre, L., Muenter, M. D., Moertel, C., Zimmerman, B. R., Lindor, K., Smith, C., Kottke, T., Ahlskog, J. E., Reed, C., Scott, R., Rehder, K. A. I., Ory, S., Maddox, D. E., Vassallo, M., Steadman, C., Lennon, R., Nishimura, R., Khanderia, B., Benarroch, E., Cheesbro, J., Jett, J., Baratz, K., Loeb, D., Rodeheffer, R., Connolly, D., Heath, H., Szurszewski, J., Flickinger, A., Rumberger, J., Humes, R., Debolt, M., Zimmerman, D., Chesebro, J., Schirger, A., Callaway, C., Chesebro, J. H., Bergstrom, L., Mock, M., Kottke, B., Ebeling, P., Kalthoff, L., McCannal, C., Hayes, D., Shepard, J., Sheridan, P., Yunginger, J. W., Edmonson, J., Tiegs, R. D., Burritt, M., Chesebro, J., Beckett, V., Lin, S., Matsumoto, J., Thistle, J., Gleich, G., Lufkin, E., Larusso, N., Miser, J., Rodeheffer, R., Kovach, J., Wooten, R., Boerwinkle, E., Ruegemer, J., Hodgson, S., Katz, K., Krayer, S., Yunginger, J., Strong, C., Fleming, C., vandyke, R., Schneider, T., Calvo, M., Goronzy, J., Chao, E., Jacobs, L., Beers, T., Eastell, R. M., Homan, M., Fick, A., Gerich, J., Miedema, B., Frye, R. L., Margulies, K., Perry, R., Martin, W., Marcoux, J., Degroen, P., Di Magno, E., Malagelada, J., Gross, J. B., Holmes, D., Litzow, M., Griggs, R., Cortese, D., Miser, J., Reed, C. E., Proana, M., Weinshilboum, R., Prendergast, F., Hunt, L., Phillips, S., Jones, K., Mock, M., Butler, P., Bourne, W., Li, J., Gross, J., Miller, W., Berger, P., Simon, P., Ahlquist, D., Porayko, M., Cooper, L., Arndt, C., Nguyen, T., Greipp, P., Rubin, J., Prather, C., Khandheria, B. K., Pemberton, J., Gilchrist, G., Vockley, G., Schwenk, F., Williams, A., Sinaki, M., Noseworthy, J., Dimagno, E., Gorman, C., Hensrud, D., Kopecky, S., Wang, K., Gay, P., Zimmerman, B., Burnett, J., Fitzpatrick, L., French, A., Nehra, V., Bengtson, K., Goldberg, R., Dumesic, D., Brubaker, R., Beck, K., Burch, P., Hurley, D., Sarano, M., Sandborn, W., Ames, M., Mazlumzadeh, M., Rodeheffer, R. J., Service, F. J., Adjei, A., Riggs, B. L., Schwenk, W. F., Dickson, E. R., Ahlquist, D., Talley, N., Murray, J., Oconnell, M., Burnett, J., Harper, C., Brennan, M., Sheedy, P., Mauras, N., Vittone, J., Dietz, N., Sim, F., Melton, J., Zimmerman, D., Meissner, I., Rummans, T., Anderson, P., Darmaun, D., Perez, E., Arndt, C., Coulie, B., Paya, C., Cooper, L., Dupras, D., McPhail, I., Kopecky, S., Minson, C., Reid, K., Reid, K., Dotson, R., Cameron, A., Nielsen, S., Morgenstern, B., Lacy, M., Bunch, T., Halliwill, J. R., Rosado, B., Pruthi, R., Thompson, W., Meissner, I., Eghbali-Fatourechi, G., Benrud-Larson, L., Bruce-Neeley, B., Sletteen, [. V., Barrette, B., Romero, Y., Saito Loftus, Y., Canzanello, V., Kirmani, S., Jean, F., Lacy, M., Heit, J., Kotagal, S., Arndt, C., Morrey, B., Dietz, N., Enriquez-Sarano, M., Rihal, C., Chareonthaitawee, P., Dahm, D., Jacobsen, S., Port, J. D., Phy, J., Charkoudian, N., Pitot, H., Maraganore, D. M., Sheedy, P., Foxx-Orenstein, A., Lieber, M., Skoog, S., Gonenne, J., Lanningham-Foster, L., Caples, S. M., Tsang, T. S. M., Frantz, R., Masuki, S., Martin, D., Eghbali Fatourechi, G., Thornhill, A., Sundt, T., Gami, A., Nyberg, S., Buttar, N., Sarkaria, J., Kim, H., O'Connell, P., Firek, A., Kennedy, F., Haymond, M. W., Klein, K., McMahon, M., Cortese, D. A., Hsu, J., Wilson, D., Ahlskog, J. E., Reed, C., Maddox, D. E., Vassallo, M., Szurszewski, J., Ebeling, P., Edmonson, J., Tiegs, R. D., Lin, S., Krayer, S., Jacobs, L., Frye, R. L., Perry, R., Gross, J. B., Reed, C. E., Weinshilboum, R., Butler, P., Simon, P., Nguyen, T., Rubin, J., Sinaki, M., Wang, K., Rodeheffer, R. J., John Service, F., Lawrence Riggs, B., Frederick Schwenk, W., Rolland Dickson, E., Vittone, J., Sletteen, Foxx-Orenstein, A., Sarkaria, J., Litzow, M. R., Murray, J. A., Frantz, R., Rihal, C., Burnett, J. C. J., Adjei, A., Lacy, M., Lacy, M. & Holmes, D.

National Institutes of Health

12/1/76 → 11/30/09

Project: Research project

Insulin
Glucose
Type 2 Diabetes Mellitus
Muscles
Glucagon

Research Output 1988 2019

Exercise and metformin counteract altered mitochondrial function in the insulinresistant brain

Ruegsegger, G. N., Vanderboom, P. M., Dasari, S., Klaus, K. A., Kabiraj, P., McCarthy, C. B., Lucchinetti, C. F. & Nair, K. S., Sep 19 2019, In : JCI Insight. 4, 18, e130681.

Research output: Contribution to journal › Article

Open Access
Metformin
Insulin Resistance
Insulin Receptor
Brain
Insulin

Phosphodiesterase 10A IgG: A novel biomarker of paraneoplastic neurologic autoimmunity

Zekeridou, A., Kryzer, T., Guo, Y., Hassan, A., Lennon, V. A., Lucchinetti, C. F., Pittock, S. J. & McKeon, A., Aug 20 2019, In : Neurology. 93, 8, p. e815-e822

Research output: Contribution to journal › Article

Open Access
Phosphoric Diester Hydrolases
Autoimmunity
Nervous System
Immunoglobulin G
Biomarkers
7 Citations (Scopus)

Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders

International Conference on Spinal Cord Involvement and Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders, Feb 1 2019, In : The Lancet Neurology. 18, 2, p. 185-197 13 p.

Research output: Contribution to journal › Review article

Neuromyelitis Optica
Multiple Sclerosis
Spinal Cord
Spinal Cord Diseases
Biomarkers
1 Citation (Scopus)

Using germline variants to estimate glioma and subtype risks

Eckel-Passow, J. E., Decker, P. A., Kosel, M. L., Kollmeyer, T. M., Molinaro, A. M., Rice, T., Caron, A. A., Drucker, K. L., Praska, C. E., Pekmezci, M., Hansen, H. M., Mccoy, L. S., Bracci, P. M., Erickson, B. J., Lucchinetti, C. F., Wiemels, J. L., Wiencke, J. K., Bondy, M. L., Melin, B., Burns, T. & 4 others, Giannini, C., Lachance, D. H., Wrensch, M. R. & Jenkins, R. B., Mar 18 2019, In : Neuro-oncology. 21, 4, p. 451-461 11 p.

Research output: Contribution to journal › Article

Glioma
Isocitrate Dehydrogenase
Single Nucleotide Polymorphism
Logistic Models
Mutation
20 Citations (Scopus)

Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Autoantibody Status Predict Outcome of Recurrent Optic Neuritis

Jitprapaikulsan, J., Chen, J., Flanagan, E., Tobin, W. O., Fryer, J. P., Weinshenker, B. G., McKeon, A., Lennon, V. A., Leavitt, J. A., Tillema, J-M., Lucchinetti, C. F., Keegan, B. M., Kantarci, O. H., Khanna, C., Jenkins, S. M., Spears, G. M., Sagan, J. & Pittock, S. J., Jan 1 2018, (Accepted/In press) In : Ophthalmology.

Research output: Contribution to journal › Article

Myelin-Oligodendrocyte Glycoprotein
Aquaporin 4
Optic Neuritis
Autoantibodies
Immunoglobulin G