Amit Mahipal, MBBS

  • 1314 Citations
  • 17 Scopus h-Index
20052020

Research output per year

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Research Output

2020

A novel clinically based staging system for gallbladder cancer

Yadav, S., Tella, S. H., Kommalapati, A., Mara, K., Prasai, K., Mady, M. H., Hassan, M., Smoot, R. L., Cleary, S. P., Truty, M. J., Roberts, L. R. & Mahipal, A., 2020, In : JNCCN Journal of the National Comprehensive Cancer Network. 18, 2, p. 151-159 9 p.

Research output: Contribution to journalArticle

A Phase 2 Multi-institutional Study of Nivolumab for Patients with Advanced Refractory Biliary Tract Cancer

Kim, R. D., Chung, V., Alese, O. B., El-Rayes, B. F., Li, D., Al-Toubah, T. E., Schell, M. J., Zhou, J. M., Mahipal, A., Kim, B. H. & Kim, D. W., Jun 2020, In : JAMA Oncology. 6, 6, p. 888-894 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study

Lee, M. S., Ryoo, B. Y., Hsu, C. H., Numata, K., Stein, S., Verret, W., Hack, S. P., Spahn, J., Liu, B., Abdullah, H., Wang, Y., He, A. R., Lee, K. H., Bang, Y. J., Bendell, J., Chao, Y., Chen, J. S., Chung, H. C., Davis, S. L., Dev, A. & 20 others, Gane, E., George, B., He, A. R., Hochster, H., Hsu, C. H., Ikeda, M., Lee, J., Lee, M., Mahipal, A., Manji, G., Morimoto, M., Numata, K., Pishvaian, M., Qin, S., Ryan, D., Ryoo, B. Y., Sasahira, N., Stein, S., Strickler, J. & Tebbutt, N., Jun 2020, In : The Lancet Oncology. 21, 6, p. 808-820 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Multidisciplinary management of liver, pancreatic, and gastric malignancies in older adults

DePeralta, D. K., Frakes, J., Mahipal, A., Saeed, N., Almhanna, K., Kim, R. & Anaya, D. A., Jan 1 2020, Geriatric Oncology. Springer International Publishing, p. 731-757 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neutrophil to lymphocyte ratio as a prognostic marker in metastatic gallbladder cancer

Mady, M., Prasai, K., Tella, S. H., Yadav, S., Hallemeier, C. L., Rakshit, S., Roberts, L., Borad, M. & Mahipal, A., Jan 1 2020, (Accepted/In press) In : HPB.

Research output: Contribution to journalArticle

1 Scopus citations

Novel staging system using carbohydrate antigen (CA) 19-9 in extra-hepatic cholangiocarcinoma and its implications on overall survival: CA19-9 in the staging of extra-hepatic cholangiocarcinoma

Tella, S. H., Kommalapati, A., Yadav, S., Bergquist, J. R., Goyal, G., Durgin, L., Borad, M., Cleary, S. P., Truty, M. J. & Mahipal, A., May 2020, In : European Journal of Surgical Oncology. 46, 5, p. 789-795 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Patient-Reported Quality of Life Before and After Chemoradiation for Intact Pancreas Cancer: A Prospective Registry Study

Breen, W. G., Jethwa, K. R., Yu, N. Y., Spears, G. M., Harmsen, W. S., Miller, R. C., Ashman, J. B., Rule, W., Sio, T. T., Neben-Wittich, M. A., Haddock, M. G., Mahipal, A., Truty, M., Hallemeier, C. L. & Merrell, K. W., 2020, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer

Kim, R. D., Azad, N. S., Morse, M. A., Poplin, E., Mahipal, A., Tan, B., Mavroukakis, S. A., Fantini, M., Tsang, K. Y., Zaki, A., Torrealba, J., Arlen, P. M. & Beg, M. S., Jul 15 2020, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 14, p. 3557-3564 8 p.

Research output: Contribution to journalArticle

Phase II Trial of Trifluridine/Tipiracil in Patients with Advanced, Refractory Biliary Tract Carcinoma

Chakrabarti, S., Zemla, T. J., Ahn, D. H., Ou, F. S., Fruth, B., Borad, M. J., Hartgers, M. L., Wessling, J., Walkes, R. L., Alberts, S. R., McWilliams, R. R., Liu, M. C., Durgin, L. M., Bekaii-Saab, T. S. & Mahipal, A., May 1 2020, In : Oncologist. 25, 5, p. 380-e763

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Preclinical assessment with clinical validation of selinexor with gemcitabine and nab-paclitaxel for the treatment of pancreatic ductal adenocarcinoma

Azmi, A. S., Khan, H. Y., Muqbil, I., Aboukameel, A., Neggers, J. E., Daelemans, D., Mahipal, A., Dyson, G., Kamgar, M., Al-Hallak, M. N., Tesfaye, A., Kim, S., Shidham, V., Mohammad, R. M. & Philip, P. A., Mar 15 2020, In : Clinical Cancer Research. 26, 6, p. 1338-1348 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access

Second-line therapies in advanced biliary tract cancers

Tella, S. H., Kommalapati, A., Borad, M. J. & Mahipal, A., Jan 2020, In : The Lancet Oncology. 21, 1, p. e29-e41

Research output: Contribution to journalReview article

3 Scopus citations

Survival and prognostic factors in patients with rectal squamous cell carcinoma

Kommalapati, A., Tella, S. H., Yadav, S., Goyal, G., Hallemeier, C., Durgin, L., Jin, Z. & Mahipal, A., Jun 2020, In : European Journal of Surgical Oncology. 46, 6, p. 1111-1117 7 p.

Research output: Contribution to journalArticle

Targeted therapies in advanced biliary tract cancer: An evolving paradigm

Chakrabarti, S., Kamgar, M. & Mahipal, A., Aug 2020, In : Cancers. 12, 8, p. 1-21 21 p., 2039.

Research output: Contribution to journalReview article

Open Access

The efficacy, safety, and predictors of outcomes of transarterial radioembolization for hepatocellular carcinoma: a retrospective study

Abdallah, M. A., Wongjarupong, N., Hassan, M. A., Taha, W., Abdalla, A., Bampoh, S., Onyirioha, K., Nelson, M., Glubranson, L. A., Wiseman, G. A., Fleming, C. J., Andrews, J. C., Mahipal, A. & Roberts, L. R., Jul 2 2020, In : Expert Review of Gastroenterology and Hepatology. 14, 7, p. 619-629 11 p.

Research output: Contribution to journalArticle

2019

A phase 2 study of an oral mTORC1/mTORC2 kinase inhibitor (CC-223) for non-pancreatic neuroendocrine tumors with or without carcinoid symptoms

Wolin, E., Mita, A., Mahipal, A., Meyer, T., Bendell, J., Nemunaitis, J., Munster, P. N., Paz-Ares, L., Filvaroff, E. H., Li, S., Hege, K., de Haan, H. & Mita, M., Sep 1 2019, In : PloS one. 14, 9, e0221994.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Association between treatment facility volume, therapy types and overall survival in patients with intrahepatic cholangiocarcinoma

Kommalapati, A., Tella, S. H., Goyal, G., Borad, M., Alberts, S. R., Roberts, L., Hubbard, J. M., Durgin, L., Cleary, S. & Mahipal, A., Mar 2019, In : HPB. 21, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinicopathological features and outcomes of fibrolamellar hepatocellular carcinoma

Chakrabarti, S., Tella, S. H., Kommalapati, A., Huffman, B. M., Yadav, S., Riaz, I. B., Goyal, G., Mody, K., Borad, M., Cleary, S., Smoot, R. L. & Mahipal, A., 2019, In : Journal of Gastrointestinal Oncology. 10, 3, p. 554-561 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Combined PIK3CA and FGFR inhibition with alpelisib and infigratinib in patients with PIK3CA-mutant solid tumors, with or without fgfr alterations

Hyman, D. M., Tran, B., Paz-Ares, L., MacHiels, J. P., Schellens, J. H., Bedard, P. L., Campone, M., Cassier, P. A., Sarantopoulos, J., Vaishampayan, U., Chugh, R., Mahipal, A., Lockhart, A. C., Sessa, C., Zander, T., Ng, M., Curigliano, G., Bendiske, J., Chen, X., Choudhury, S. & 4 others, Graus-Porta, D., Lewis, N., Garcia, J. M. P. & De Miguel-Luken, M. J., 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

Open Access

Evaluating the safety and efficacy of nivolumab in patients with advanced hepatocellular carcinoma: Evidence to date

Tella, S. H., Mahipal, A., Kommalapati, A. & Jin, Z., 2019, In : OncoTargets and Therapy. 12, p. 10335-10342 8 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

FGFR2 genomic aberrations: Achilles heel in the management of advanced cholangiocarcinoma

Mahipal, A., Tella, S. H., Kommalapati, A., Anaya, D. & Kim, R., Aug 2019, In : Cancer Treatment Reviews. 78, p. 1-7 7 p.

Research output: Contribution to journalReview article

7 Scopus citations

First-in-human phase 1 dose-escalating trial of G305 in patients with advanced solid tumors expressing NY-ESO-1

Mahipal, A., Ejadi, S., Gnjatic, S., Kim-Schulze, S., Lu, H., ter Meulen, J. H., Kenney, R. & Odunsi, K., Jan 1 2019, In : Cancer Immunology, Immunotherapy.

Research output: Contribution to journalArticle

4 Scopus citations

First-in-human phase i study of a dual mTOR kinase and DNA-PK inhibitor (CC-115) in advanced malignancy

Munster, P., Mita, M., Mahipal, A., Nemunaitis, J., Massard, C., Mikkelsen, T., Cruz, C., Paz-Ares, L., Hidalgo, M., Rathkopf, D., Blumenschein, G., Smith, D. C., Eichhorst, B., Cloughesy, T., Filvaroff, E. H., Li, S., Raymon, H., de Haan, H., Hege, K. & Bendell, J. C., 2019, In : Cancer Management and Research. 11, p. 10463-10476 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Immunotherapy in hepatocellular carcinoma: Is there a light at the end of the tunnel?

Mahipal, A., Tella, S. H., Kommalapati, A., Lim, A. & Kim, R., Aug 2019, In : Cancers. 11, 8, 1078.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

Local excision for patients with stage I anal canal squamous cell carcinoma can be curative

Chakrabarti, S., Jin, Z., Huffman, B. M., Yadav, S., Graham, R. P., Lam-Himlin, D. M., Lightner, A. L., Hallemeier, C. L. & Mahipal, A., Apr 1 2019, In : Journal of Gastrointestinal Oncology. 10, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Neoadjuvant vs. adjuvant chemotherapy for cholangiocarcinoma: A propensity score matched analysis

Yadav, S., Xie, H., Bin-Riaz, I., Sharma, P., Durani, U., Goyal, G., Borah, B. J., Borad, M. J., Smoot, R., Roberts, L. R., Go, R. S., Mc Williams, R. R. & Mahipal, A., Jan 1 2019, In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

6 Scopus citations

Novel Prognostic Factors in Resected Small Bowel Adenocarcinoma

Huffman, B. M., Jin, Z., Yadav, S., Patel, S., Nagorney, D. M., Truty, M. J., McWilliams, R. R., Halfdanarson, T. R. & Mahipal, A., Sep 2019, In : Clinical colorectal cancer. 18, 3, p. 218-225 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Solid Pseudopapillary Neoplasms of the Pancreas: A Large American Cohort

Sanhueza, C. T., Huffman, B. M., Jin, Z., Hartgers, M. L., Smyrk, T. C., Westin, G., Mc Williams, R. R., Ma, W. W., Alberts, S. R. & Mahipal, A., Apr 1 2019, In : Pancreas. 48, 4, p. E21-E22

Research output: Contribution to journalLetter

Survival and prognostic factors in patients with pancreatic squamous cell carcinoma

Tella, S. H., Kommalapati, A., Yadav, S., Bergquist, J. R., Truty, M. J., Durgin, L., Ma, W. W., Cleary, S. P., McWilliams, R. R. & Mahipal, A., Sep 2019, In : European Journal of Surgical Oncology. 45, 9, p. 1700-1705 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Clinical Outcomes of Patients With Gastrointestinal Malignancies Participating in Phase I Clinical Trials

Denson, A., Burke, N., Wapinsky, G., Bertels, B., Juan, T. H., Lee, J., Springett, G. M., Strosberg, J. R., Kim, R. D., Sullivan, D. M. & Mahipal, A., 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 2, p. 133-139 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Contemporary management of localized resectable pancreatic cancer

Kommalapati, A., Tella, S. H., Goyal, G., Ma, W. W. & Mahipal, A., Jan 20 2018, In : Cancers. 10, 1, 24.

Research output: Contribution to journalReview article

17 Scopus citations

Neoadjuvant vs. adjuvant chemotherapy for cholangiocarcinoma: A propensity score matched analysis

Yadav, S., Xie, H., Riaz, I. B., Sharma, P., Mahipal, A. & McWilliams, R., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii260-viii261

Research output: Contribution to journalArticle

Open Access

Novel immunotherapy strategies for hepatobiliary cancers

Deleon, T. T., Zhou, Y., Nagalo, B. M., Yokoda, R. T., Ahn, D. H., Ramanathan, R. K., Salomao, M. A., Aqel, B. A., Mahipal, A., Bekaii-Saab, T. S. & Borad, M. J., Sep 1 2018, In : Immunotherapy. 10, 12, p. 1077-1091 15 p.

Research output: Contribution to journalReview article

Novel targeted treatment options for advanced cholangiocarcinoma

Mahipal, A., Kommalapati, A., Tella, S. H., Lim, A. & Kim, R., Sep 2 2018, In : Expert Opinion on Investigational Drugs. 27, 9, p. 709-720 12 p.

Research output: Contribution to journalReview article

12 Scopus citations

Phase 1 trial of enzalutamide in combination with gemcitabine and nab-paclitaxel for the treatment of advanced pancreatic cancer

Mahipal, A., Tella, S. H., Kommalapati, A., Goyal, G., Soares, H., Neuger, A., Copolla, D., Kim, J. & Kim, R., Jan 1 2018, (Accepted/In press) In : Investigational New Drugs.

Research output: Contribution to journalArticle

3 Scopus citations

Prognostic factors and benefits of adjuvant therapy after pancreatoduodenectomy for ampullary adenocarcinoma: Mayo Clinic experience

Jin, Z., Hartgers, M. L., Sanhueza, C. T., Shubert, C. R., Alberts, S. R., Truty, M., Muppa, P., Nagorney, D. M., Smyrk, T. C., Hassan, M. & Mahipal, A., Jan 1 2018, (Accepted/In press) In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

13 Scopus citations

Rho GTPase effectors and NAD metabolism in cancer immune suppression

Chaker, M., Minden, A., Chen, S., Weiss, R. H., Chini, E. N., Mahipal, A. & Azmi, A. S., Jan 2 2018, In : Expert opinion on therapeutic targets. 22, 1, p. 9-17 9 p.

Research output: Contribution to journalReview article

6 Scopus citations

Survival and Prognostic Factors in Patients with Solid Pseudopapillary Neoplasms of the Pancreas

Huffman, B. M., Westin, G., Alsidawi, S., Alberts, S. R., Nagorney, D. M., Halfdanarson, T. R. & Mahipal, A., Sep 1 2018, In : Pancreas. 47, 8, p. 1003-1007 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Use of Radiation Therapy in Locally Advanced Pancreatic Cancer Improves Survival

Sajjad, M., Batra, S., Hoffe, S., Kim, R., Springett, G. & Mahipal, A., Jan 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 3, p. 236-241 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

EGFR Inhibitors in Patients with Advanced Squamous Cell Anal Carcinomas: A Single-Institution Experience

Kim, D. W., Byer, J., Kothari, N., Mahipal, A., Chang, Y. D. & Kim, R. D., Apr 1 2017, In : Oncology (Switzerland). 92, 4, p. 190-196 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Phase I dose-escalation and -expansion study of the BRAF inhibitor encorafenib (LGX818) in metastatic BRAF-mutant melanoma

Delord, J. P., Robert, C., Nyakas, M., McArthur, G. A., Kudchakar, R., Mahipal, A., Yamada, Y., Sullivan, R., Arance, A., Kefford, R. F., Carlino, M. S., Hidalgo, M., Gomez-Roca, C., Michel, D., Seroutou, A., Aslanis, V., Caponigro, G., Stuart, D. D., Moutouh-De Parseval, L., Demuth, T. & 1 others, Dummer, R., Sep 15 2017, In : Clinical Cancer Research. 23, 18, p. 5339-5348 10 p.

Research output: Contribution to journalArticle

56 Scopus citations

Phase i trial of the human double minute 2 inhibitor MK-8242 in patients with advanced solid tumors

Wagner, A. J., Banerji, U., Mahipal, A., Somaiah, N., Hirsch, H., Fancourt, C., Johnson-Levonas, A. O., Lam, R., Meister, A. K., Russo, G., Knox, C. D., Rose, S. & Hong, D. S., Apr 20 2017, In : Journal of Clinical Oncology. 35, 12, p. 1304-1311 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Staging and prognostic implications

Mahipal, A. & Kim, R., Sep 27 2017, Current and Emerging Therapies in Pancreatic Cancer. Springer International Publishing, p. 109-118 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Antitumor activity of pembrolizumab in biomarker-unselected patients with recurrent and/or metastatic head and neck squamous cell carcinoma: Results from the phase Ib KEYNOTE-012 expansion cohort

Chow, L. Q. M., Haddad, R., Gupta, S., Mahipal, A., Mehra, R., Tahara, M., Berger, R., Eder, J. P., Burtness, B., Lee, S. H., Keam, B., Kang, H., Muro, K., Weiss, J., Geva, R., Lin, C. C., Chung, H. C., Meister, A., Dolled-Filhart, M., Pathiraja, K. & 2 others, Cheng, J. D. & Seiwert, T. Y., Nov 10 2016, In : Journal of Clinical Oncology. 34, 32, p. 3838-3845 8 p.

Research output: Contribution to journalArticle

356 Scopus citations

Effect of metformin use on survival in resectable pancreatic cancer: A single-institution experience and review of the literature

Ambe, C. M., Mahipal, A., Fulp, J., Chen, L. & Malafaxs, M. P., Mar 2016, In : PloS one. 11, 3, e0151632.

Research output: Contribution to journalReview article

26 Scopus citations

First-in-class, first-in-human phase I study of selinexor, a selective inhibitor of nuclear export, in patients with advanced solid tumors

Abdul Razak, A. R., Mau-Soerensen, M., Gabrail, N. Y., Gerecitano, J. F., Shields, A. F., Unger, T. J., Saint-Martin, J. R., Carlson, R., Landesman, Y., McCauley, D., Rashal, T., Lassen, U., Kim, R., Stayner, L. A., Mirza, M. R., Kauffman, M., Shacham, S. & Mahipal, A., Dec 1 2016, In : Journal of Clinical Oncology. 34, 34, p. 4142-4150 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Importins and exportins as therapeutic targets in cancer

Mahipal, A. & Malafa, M., Aug 1 2016, In : Pharmacology and Therapeutics. 164, p. 135-143 9 p.

Research output: Contribution to journalReview article

56 Scopus citations

Malignant transformation of biliary adenofibroma: A rare biliary cystic tumor

Thompson, S. M., Zendejas-Mummert, B., Hartgers, M. L., Venkatesh, S. K., Smyrk, T. C., Mahipal, A. & Smoot, R. L., 2016, In : Journal of Gastrointestinal Oncology. 7, 6, p. E107-E112

Research output: Contribution to journalArticle

1 Scopus citations