Amit Mahipal, MBBS

  • 1297 Citations
  • 17 Scopus h-Index
20052020

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2020

A novel clinically based staging system for gallbladder cancer

Yadav, S., Tella, S. H., Kommalapati, A., Mara, K., Prasai, K., Mady, M. H., Hassan, M., Smoot, R. L., Cleary, S. P., Truty, M. J., Roberts, L. R. & Mahipal, A., 2020, In : JNCCN Journal of the National Comprehensive Cancer Network. 18, 2, p. 151-159 9 p.

Research output: Contribution to journalArticle

A Phase 2 Multi-institutional Study of Nivolumab for Patients with Advanced Refractory Biliary Tract Cancer

Kim, R. D., Chung, V., Alese, O. B., El-Rayes, B. F., Li, D., Al-Toubah, T. E., Schell, M. J., Zhou, J. M., Mahipal, A., Kim, B. H. & Kim, D. W., Jun 2020, In : JAMA Oncology. 6, 6, p. 888-894 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study

Lee, M. S., Ryoo, B. Y., Hsu, C. H., Numata, K., Stein, S., Verret, W., Hack, S. P., Spahn, J., Liu, B., Abdullah, H., Wang, Y., He, A. R., Lee, K. H., Bang, Y. J., Bendell, J., Chao, Y., Chen, J. S., Chung, H. C., Davis, S. L., Dev, A. & 20 others, Gane, E., George, B., He, A. R., Hochster, H., Hsu, C. H., Ikeda, M., Lee, J., Lee, M., Mahipal, A., Manji, G., Morimoto, M., Numata, K., Pishvaian, M., Qin, S., Ryan, D., Ryoo, B. Y., Sasahira, N., Stein, S., Strickler, J. & Tebbutt, N., Jun 2020, In : The Lancet Oncology. 21, 6, p. 808-820 13 p.

Research output: Contribution to journalArticle

Neutrophil to lymphocyte ratio as a prognostic marker in metastatic gallbladder cancer

Mady, M., Prasai, K., Tella, S. H., Yadav, S., Hallemeier, C. L., Rakshit, S., Roberts, L., Borad, M. & Mahipal, A., Jan 1 2020, (Accepted/In press) In : HPB.

Research output: Contribution to journalArticle

1 Scopus citations

Novel staging system using carbohydrate antigen (CA) 19-9 in extra-hepatic cholangiocarcinoma and its implications on overall survival: CA19-9 in the staging of extra-hepatic cholangiocarcinoma

Tella, S. H., Kommalapati, A., Yadav, S., Bergquist, J. R., Goyal, G., Durgin, L., Borad, M., Cleary, S. P., Truty, M. J. & Mahipal, A., May 2020, In : European Journal of Surgical Oncology. 46, 5, p. 789-795 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Patient-Reported Quality of Life Before and After Chemoradiation for Intact Pancreas Cancer: A Prospective Registry Study

Breen, W. G., Jethwa, K. R., Yu, N. Y., Spears, G. M., Harmsen, W. S., Miller, R. C., Ashman, J. B., Rule, W., Sio, T. T., Neben-Wittich, M. A., Haddock, M. G., Mahipal, A., Truty, M., Hallemeier, C. L. & Merrell, K. W., 2020, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer

Kim, R. D., Azad, N. S., Morse, M. A., Poplin, E., Mahipal, A., Tan, B., Mavroukakis, S. A., Fantini, M., Tsang, K. Y., Zaki, A., Torrealba, J., Arlen, P. M. & Beg, M. S., Jul 15 2020, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 14, p. 3557-3564 8 p.

Research output: Contribution to journalArticle

Phase II Trial of Trifluridine/Tipiracil in Patients with Advanced, Refractory Biliary Tract Carcinoma

Chakrabarti, S., Zemla, T. J., Ahn, D. H., Ou, F. S., Fruth, B., Borad, M. J., Hartgers, M. L., Wessling, J., Walkes, R. L., Alberts, S. R., McWilliams, R. R., Liu, M. C., Durgin, L. M., Bekaii-Saab, T. S. & Mahipal, A., May 1 2020, In : Oncologist. 25, 5, p. 380-e763

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Preclinical assessment with clinical validation of selinexor with gemcitabine and nab-paclitaxel for the treatment of pancreatic ductal adenocarcinoma

Azmi, A. S., Khan, H. Y., Muqbil, I., Aboukameel, A., Neggers, J. E., Daelemans, D., Mahipal, A., Dyson, G., Kamgar, M., Al-Hallak, M. N., Tesfaye, A., Kim, S., Shidham, V., Mohammad, R. M. & Philip, P. A., Mar 15 2020, In : Clinical Cancer Research. 26, 6, p. 1338-1348 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access

Survival and prognostic factors in patients with rectal squamous cell carcinoma

Kommalapati, A., Tella, S. H., Yadav, S., Goyal, G., Hallemeier, C., Durgin, L., Jin, Z. & Mahipal, A., Jun 2020, In : European Journal of Surgical Oncology. 46, 6, p. 1111-1117 7 p.

Research output: Contribution to journalArticle

The efficacy, safety, and predictors of outcomes of transarterial radioembolization for hepatocellular carcinoma: a retrospective study

Abdallah, M. A., Wongjarupong, N., Hassan, M. A., Taha, W., Abdalla, A., Bampoh, S., Onyirioha, K., Nelson, M., Glubranson, L. A., Wiseman, G. A., Fleming, C. J., Andrews, J. C., Mahipal, A. & Roberts, L. R., Jul 2 2020, In : Expert Review of Gastroenterology and Hepatology. 14, 7, p. 619-629 11 p.

Research output: Contribution to journalArticle

2019

A phase 2 study of an oral mTORC1/mTORC2 kinase inhibitor (CC-223) for non-pancreatic neuroendocrine tumors with or without carcinoid symptoms

Wolin, E., Mita, A., Mahipal, A., Meyer, T., Bendell, J., Nemunaitis, J., Munster, P. N., Paz-Ares, L., Filvaroff, E. H., Li, S., Hege, K., de Haan, H. & Mita, M., Sep 1 2019, In : PloS one. 14, 9, e0221994.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Association between treatment facility volume, therapy types and overall survival in patients with intrahepatic cholangiocarcinoma

Kommalapati, A., Tella, S. H., Goyal, G., Borad, M., Alberts, S. R., Roberts, L., Hubbard, J. M., Durgin, L., Cleary, S. & Mahipal, A., Mar 2019, In : HPB. 21, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinicopathological features and outcomes of fibrolamellar hepatocellular carcinoma

Chakrabarti, S., Tella, S. H., Kommalapati, A., Huffman, B. M., Yadav, S., Riaz, I. B., Goyal, G., Mody, K., Borad, M., Cleary, S., Smoot, R. L. & Mahipal, A., 2019, In : Journal of Gastrointestinal Oncology. 10, 3, p. 554-561 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Combined PIK3CA and FGFR inhibition with alpelisib and infigratinib in patients with PIK3CA-mutant solid tumors, with or without fgfr alterations

Hyman, D. M., Tran, B., Paz-Ares, L., MacHiels, J. P., Schellens, J. H., Bedard, P. L., Campone, M., Cassier, P. A., Sarantopoulos, J., Vaishampayan, U., Chugh, R., Mahipal, A., Lockhart, A. C., Sessa, C., Zander, T., Ng, M., Curigliano, G., Bendiske, J., Chen, X., Choudhury, S. & 4 others, Graus-Porta, D., Lewis, N., Garcia, J. M. P. & De Miguel-Luken, M. J., 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

Open Access

First-in-human phase 1 dose-escalating trial of G305 in patients with advanced solid tumors expressing NY-ESO-1

Mahipal, A., Ejadi, S., Gnjatic, S., Kim-Schulze, S., Lu, H., ter Meulen, J. H., Kenney, R. & Odunsi, K., Jan 1 2019, In : Cancer Immunology, Immunotherapy.

Research output: Contribution to journalArticle

4 Scopus citations

First-in-human phase i study of a dual mTOR kinase and DNA-PK inhibitor (CC-115) in advanced malignancy

Munster, P., Mita, M., Mahipal, A., Nemunaitis, J., Massard, C., Mikkelsen, T., Cruz, C., Paz-Ares, L., Hidalgo, M., Rathkopf, D., Blumenschein, G., Smith, D. C., Eichhorst, B., Cloughesy, T., Filvaroff, E. H., Li, S., Raymon, H., de Haan, H., Hege, K. & Bendell, J. C., 2019, In : Cancer Management and Research. 11, p. 10463-10476 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Local excision for patients with stage I anal canal squamous cell carcinoma can be curative

Chakrabarti, S., Jin, Z., Huffman, B. M., Yadav, S., Graham, R. P., Lam-Himlin, D. M., Lightner, A. L., Hallemeier, C. L. & Mahipal, A., Apr 1 2019, In : Journal of Gastrointestinal Oncology. 10, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Neoadjuvant vs. adjuvant chemotherapy for cholangiocarcinoma: A propensity score matched analysis

Yadav, S., Xie, H., Bin-Riaz, I., Sharma, P., Durani, U., Goyal, G., Borah, B. J., Borad, M. J., Smoot, R., Roberts, L. R., Go, R. S., Mc Williams, R. R. & Mahipal, A., Jan 1 2019, In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

6 Scopus citations

Novel Prognostic Factors in Resected Small Bowel Adenocarcinoma

Huffman, B. M., Jin, Z., Yadav, S., Patel, S., Nagorney, D. M., Truty, M. J., McWilliams, R. R., Halfdanarson, T. R. & Mahipal, A., Sep 2019, In : Clinical colorectal cancer. 18, 3, p. 218-225 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Survival and prognostic factors in patients with pancreatic squamous cell carcinoma

Tella, S. H., Kommalapati, A., Yadav, S., Bergquist, J. R., Truty, M. J., Durgin, L., Ma, W. W., Cleary, S. P., McWilliams, R. R. & Mahipal, A., Sep 2019, In : European Journal of Surgical Oncology. 45, 9, p. 1700-1705 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Clinical Outcomes of Patients With Gastrointestinal Malignancies Participating in Phase I Clinical Trials

Denson, A., Burke, N., Wapinsky, G., Bertels, B., Juan, T. H., Lee, J., Springett, G. M., Strosberg, J. R., Kim, R. D., Sullivan, D. M. & Mahipal, A., 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 2, p. 133-139 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neoadjuvant vs. adjuvant chemotherapy for cholangiocarcinoma: A propensity score matched analysis

Yadav, S., Xie, H., Riaz, I. B., Sharma, P., Mahipal, A. & McWilliams, R., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii260-viii261

Research output: Contribution to journalArticle

Open Access

Phase 1 trial of enzalutamide in combination with gemcitabine and nab-paclitaxel for the treatment of advanced pancreatic cancer

Mahipal, A., Tella, S. H., Kommalapati, A., Goyal, G., Soares, H., Neuger, A., Copolla, D., Kim, J. & Kim, R., Jan 1 2018, (Accepted/In press) In : Investigational New Drugs.

Research output: Contribution to journalArticle

3 Scopus citations

Prognostic factors and benefits of adjuvant therapy after pancreatoduodenectomy for ampullary adenocarcinoma: Mayo Clinic experience

Jin, Z., Hartgers, M. L., Sanhueza, C. T., Shubert, C. R., Alberts, S. R., Truty, M., Muppa, P., Nagorney, D. M., Smyrk, T. C., Hassan, M. & Mahipal, A., Jan 1 2018, (Accepted/In press) In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

12 Scopus citations

Survival and Prognostic Factors in Patients with Solid Pseudopapillary Neoplasms of the Pancreas

Huffman, B. M., Westin, G., Alsidawi, S., Alberts, S. R., Nagorney, D. M., Halfdanarson, T. R. & Mahipal, A., Sep 1 2018, In : Pancreas. 47, 8, p. 1003-1007 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Use of Radiation Therapy in Locally Advanced Pancreatic Cancer Improves Survival

Sajjad, M., Batra, S., Hoffe, S., Kim, R., Springett, G. & Mahipal, A., Jan 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 3, p. 236-241 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

EGFR Inhibitors in Patients with Advanced Squamous Cell Anal Carcinomas: A Single-Institution Experience

Kim, D. W., Byer, J., Kothari, N., Mahipal, A., Chang, Y. D. & Kim, R. D., Apr 1 2017, In : Oncology (Switzerland). 92, 4, p. 190-196 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Phase I dose-escalation and -expansion study of the BRAF inhibitor encorafenib (LGX818) in metastatic BRAF-mutant melanoma

Delord, J. P., Robert, C., Nyakas, M., McArthur, G. A., Kudchakar, R., Mahipal, A., Yamada, Y., Sullivan, R., Arance, A., Kefford, R. F., Carlino, M. S., Hidalgo, M., Gomez-Roca, C., Michel, D., Seroutou, A., Aslanis, V., Caponigro, G., Stuart, D. D., Moutouh-De Parseval, L., Demuth, T. & 1 others, Dummer, R., Sep 15 2017, In : Clinical Cancer Research. 23, 18, p. 5339-5348 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Phase i trial of the human double minute 2 inhibitor MK-8242 in patients with advanced solid tumors

Wagner, A. J., Banerji, U., Mahipal, A., Somaiah, N., Hirsch, H., Fancourt, C., Johnson-Levonas, A. O., Lam, R., Meister, A. K., Russo, G., Knox, C. D., Rose, S. & Hong, D. S., Apr 20 2017, In : Journal of Clinical Oncology. 35, 12, p. 1304-1311 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
2016

Antitumor activity of pembrolizumab in biomarker-unselected patients with recurrent and/or metastatic head and neck squamous cell carcinoma: Results from the phase Ib KEYNOTE-012 expansion cohort

Chow, L. Q. M., Haddad, R., Gupta, S., Mahipal, A., Mehra, R., Tahara, M., Berger, R., Eder, J. P., Burtness, B., Lee, S. H., Keam, B., Kang, H., Muro, K., Weiss, J., Geva, R., Lin, C. C., Chung, H. C., Meister, A., Dolled-Filhart, M., Pathiraja, K. & 2 others, Cheng, J. D. & Seiwert, T. Y., Nov 10 2016, In : Journal of Clinical Oncology. 34, 32, p. 3838-3845 8 p.

Research output: Contribution to journalArticle

353 Scopus citations

First-in-class, first-in-human phase I study of selinexor, a selective inhibitor of nuclear export, in patients with advanced solid tumors

Abdul Razak, A. R., Mau-Soerensen, M., Gabrail, N. Y., Gerecitano, J. F., Shields, A. F., Unger, T. J., Saint-Martin, J. R., Carlson, R., Landesman, Y., McCauley, D., Rashal, T., Lassen, U., Kim, R., Stayner, L. A., Mirza, M. R., Kauffman, M., Shacham, S. & Mahipal, A., Dec 1 2016, In : Journal of Clinical Oncology. 34, 34, p. 4142-4150 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Malignant transformation of biliary adenofibroma: A rare biliary cystic tumor

Thompson, S. M., Zendejas-Mummert, B., Hartgers, M. L., Venkatesh, S. K., Smyrk, T. C., Mahipal, A. & Smoot, R. L., 2016, In : Journal of Gastrointestinal Oncology. 7, 6, p. E107-E112

Research output: Contribution to journalArticle

1 Scopus citations

Pharmacokinetics and safety of vitamin E δ-tocotrienol after single and multiple doses in healthy subjects with measurement of vitamin E metabolites

Mahipal, A., Klapman, J., Vignesh, S., Yang, C. S., Neuger, A., Chen, D. T. & Malafa, M. P., Jul 1 2016, In : Cancer chemotherapy and pharmacology. 78, 1, p. 157-165 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2015

A Meta-analysis of Randomized Clinical Trials of Chemoradiation Therapy in Locally Advanced Pancreatic Cancer

Ambe, C., Fulp, W., Springett, G., Hoffe, S. & Mahipal, A., Oct 1 2015, In : Journal of Gastrointestinal Cancer. 46, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of age on clinical outcomes in phase 1 trial participants

Mahipal, A., Denson, A. C., Djulbegovic, B., Lush, R., Kumar, A., Juan, T. H., Schell, M. J. & Sullivan, D. M., Apr 1 2015, In : Cancer Control. 22, 2, p. 235-241 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Paradoxical effect of capecitabine in 5-fluorouracil-induced cardiotoxicity: A case vignette and literature review

Saneeymehri, S. S., Markey, K. R. & Mahipal, A., Jan 1 2015, In : Journal of Oncology Pharmacy Practice. 22, 3, p. 552-555 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

PET/CT fusion scan prevents futile laparotomy in early stage pancreatic cancer

Kim, R., Prithviraj, G., Kothari, N., Springett, G., Malafa, M., Hodul, P., Kim, J., Yue, B., Morse, B. & Mahipal, A., 2015, In : Clinical nuclear medicine. 40, 11, p. e501-e505

Research output: Contribution to journalArticle

14 Scopus citations

Phase i study of combination of pasireotide LAR + gemcitabine in locally advanced or metastatic pancreatic cancer

Suleiman, Y., Mahipal, A., Shibata, D., Siegel, E. M., Jump, H., Fulp, W. J., Springett, G. M. & Kim, R., Sep 21 2015, In : Cancer Chemotherapy and Pharmacology. 76, 3, p. 481-487 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Phase i trial of combination of FOLFIRI and pasireotide, a somatostatin analogue, in advanced gastrointestinal malignancies

Mahipal, A., Shibata, D., Siegel, E., Springett, G., Almhanna, K., Fulp, W., Williams-Elson, I. & Kim, R., Oct 22 2015, In : Investigational New Drugs. 33, 5, p. 1093-1099 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Selective nuclear export inhibitor KPT-330 enhances the antitumor activity of gemcitabine in human pancreatic cancer

Kazim, S., Malafa, M. P., Coppola, D., Husain, K., Zibadi, S., Kashyap, T., Crochiere, M., Landesman, Y., Rashal, T., Sullivan, D. M. & Mahipal, A., Jul 1 2015, In : Molecular cancer therapeutics. 14, 7, p. 1570-1581 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Unexpected hepatotoxicity in a phase I study of TAS266, a novel tetravalent agonistic Nanobody® targeting the DR5 receptor

Papadopoulos, K. P., Isaacs, R., Bilic, S., Kentsch, K., Huet, H. A., Hofmann, M., Rasco, D., Kundamal, N., Tang, Z., Cooksey, J. & Mahipal, A., May 1 2015, In : Cancer Chemotherapy and Pharmacology. 75, 5, p. 887-895 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
2014

Carboplatin and paclitaxel treatment is effective in advanced anal cancer

Kim, R., Byer, J., Fulp, W. J., Mahipal, A., Dinwoodie, W. & Shibata, D., Jul 2014, In : Oncology (Switzerland). 87, 2, p. 125-132 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Epidermal growth factor receptor inhibitors: Coming of age

Mahipal, A., Kothari, N. & Gupta, S., Jan 2014, In : Cancer Control. 21, 1, p. 74-79 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Participation of the elderly population in clinical trials: Barriers and solutions

Denson, A. C. & Mahipal, A., Jul 2014, In : Cancer Control. 21, 3, p. 209-214 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Risks and benefits of phase 1 clinical trial participation

Mahipal, A. & Nguyen, D., Jul 2014, In : Cancer Control. 21, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Selinexor

Riaz, W., Burke, N. & Mahipal, A., Oct 1 2014, In : Drugs of the Future. 39, 10, p. 685-692 8 p.

Research output: Contribution to journalArticle

1 Scopus citations