Aaron J. Johnson, PhD

Professor

  • 2030 Citations
  • 25 h-Index
19982019
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  • 2 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
Theilovirus Medicine & Life Sciences
Multiple Sclerosis Medicine & Life Sciences
T-cells Chemical Compounds
Blood-Brain Barrier Medicine & Life Sciences
Demyelinating Diseases Medicine & Life Sciences
Central Nervous System Medicine & Life Sciences
Perforin Medicine & Life Sciences

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Projects 2009 2018

Tight Junctions
Blood-Brain Barrier
Capillary Permeability
Intercellular Signaling Peptides and Proteins
T-Lymphocytes
Atrophy
Brain
T-Lymphocytes
Transgenic Mice
Globoid Cell Leukodystrophy
Glioma
Picornaviridae
Immunity
Neoplasm Antigens
T-Lymphocytes
Tight Junctions
Blood-Brain Barrier
T-Lymphocytes
Brain
Capillary Permeability

Research Output 1998 2019

  • 2030 Citations
  • 25 h-Index
  • 75 Article
  • 1 Review article
3 Citations (Scopus)

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

Sterner, R. M., Sakemura, R., Cox, M. J., Yang, N., Khadka, R. H., Forsman, C. L., Hansen, M. J., Jin, F., Ayasoufi, K., Hefazi, M., Schick, K. J., Walters, D. K., Ahmed, O., Chappell, D., Sahmoud, T., Durrant, C., Nevala, W. K., Patnaik, M. M., Pease, L. R., Hedin, K. E. & 3 othersKay, N. E., Johnson, A. J. & Kenderian, S., Feb 14 2019, In : Blood. 133, 7, p. 697-709 13 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
T-Cell Antigen Receptor
Heterografts
Cytokines
Cell- and Tissue-Based Therapy

Harnessing radiation biology to augment immunotherapy for glioblastoma

Rajani, K. R., Carlstrom, L. P., Parney, I. F., Johnson, A. J., Warrington, A. E. & Burns, T., Jan 1 2019, In : Frontiers in Oncology. 9, FEB, 656.

Research output: Contribution to journalArticle

Open Access
Radiobiology
Glioblastoma
Innate Immunity
Immunotherapy
Radiation

The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network

Neier, S. C., Ferrer, A., Wilton, K. M., Smith, S. E. P., Kelcher, A. M. H., Pavelko, K. D., Canfield, J. M., Davis, T. R., Stiles, R. J., Chen, Z., McCluskey, J., Burrows, S. R., Rossjohn, J., Hebrink, D. M., Carmona Porquera, E. M., Limper, A. H., Kappes, D. J., Wettstein, P. J., Johnson, A. J., Pease, L. R. & 4 othersDaniels, M. A., Neuhauser, C., Gil, D. & Schrum, A. G., Feb 15 2019, In : Science immunology. 4, 32

Research output: Contribution to journalArticle

Protein Interaction Maps
T-Cell Antigen Receptor
Proteins
T-Lymphocytes
Thymocytes

Efficacy of the MDM2 inhibitor SAR405838 in glioblastoma is limited by poor distribution across the blood–brain barrier

Kim, M., Ma, D. J., Calligaris, D., Zhang, S., Feathers, R. W., Vaubel, R. A., Meaux, I., Mladek, A. C., Parrish, K. E., Jin, F., Barriere, C., Debussche, L., Watters, J., Tian, S., Decker, P. A., Eckel-Passow, J. E., Kitange, G. J., Johnson, A. J., Parney, I. F., Anastasiadis, P. Z. & 3 othersAgar, N. Y. R., Elmquist, W. F. & Sarkaria, J. N., Sep 1 2018, In : Molecular Cancer Therapeutics. 17, 9, p. 1893-1901 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Pharmaceutical Preparations
Gadolinium
Precision Medicine

Human perforin gene variation is geographically distributed

Willenbring, R. C., Ikeda, Y. H., Pease, L. R. & Johnson, A. J., Jan 1 2018, In : Molecular Genetics and Genomic Medicine. 6, 1, p. 44-55 12 p.

Research output: Contribution to journalArticle

Perforin
Mutation
Genes
Databases
Exome