Aaron J. Johnson, PhD

  • 2137 Citations
  • 26 Scopus h-Index
19982019
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Research Output 1998 2019

  • 2137 Citations
  • 26 Scopus h-Index
  • 77 Article
  • 1 Comment/debate
  • 1 Review article
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Article
2019
16 Citations (Scopus)

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

Sterner, R. M., Sakemura, R., Cox, M. J., Yang, N., Khadka, R. H., Forsman, C. L., Hansen, M. J., Jin, F., Ayasoufi, K., Hefazi, M., Schick, K. J., Walters, D. K., Ahmed, O., Chappell, D., Sahmoud, T., Durrant, C., Nevala, W. K., Patnaik, M. M., Pease, L. R., Hedin, K. E. & 3 others, Kay, N. E., Johnson, A. J. & Kenderian, S., Feb 14 2019, In : Blood. 133, 7, p. 697-709 13 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
T-Cell Antigen Receptor
Heterografts
Cytokines
Cell- and Tissue-Based Therapy

Harnessing radiation biology to augment immunotherapy for glioblastoma

Rajani, K. R., Carlstrom, L. P., Parney, I. F., Johnson, A. J., Warrington, A. E. & Burns, T., Jan 1 2019, In : Frontiers in Oncology. 9, FEB, 656.

Research output: Contribution to journalArticle

Open Access
Radiobiology
Glioblastoma
Immunotherapy
Radiation
Neoplasms
2 Citations (Scopus)

PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae

Wang, Z., Wang, S., Goplen, N. P., Li, C., Cheon, I. S., Dai, Q., Huang, S., Shan, J., Ma, C., Ye, Z., Xiang, M., Limper, A. H., Porquera, E. C., Kohlmeier, J. E., Kaplan, M. H., Zhang, N., Johnson, A. J., Vassallo, R. & Sun, J., Jan 1 2019, In : Science Immunology. 4, 36, eaaw1217.

Research output: Contribution to journalArticle

Immunity
T-Lymphocytes
Heterologous Immunity
Rejuvenation
Infection
1 Citation (Scopus)

The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network

Neier, S. C., Ferrer, A., Wilton, K. M., Smith, S. E. P., Kelcher, A. M. H., Pavelko, K. D., Canfield, J. M., Davis, T. R., Stiles, R. J., Chen, Z., McCluskey, J., Burrows, S. R., Rossjohn, J., Hebrink, D. M., Carmona Porquera, E. M., Limper, A. H., Kappes, D. J., Wettstein, P. J., Johnson, A. J., Pease, L. R. & 4 others, Daniels, M. A., Neuhauser, C., Gil, D. & Schrum, A. G., Feb 15 2019, In : Science immunology. 4, 32

Research output: Contribution to journalArticle

Protein Interaction Maps
T-Cell Antigen Receptor
Proteins
T-Lymphocytes
Thymocytes
2018
3 Citations (Scopus)

Efficacy of the MDM2 inhibitor SAR405838 in glioblastoma is limited by poor distribution across the blood–brain barrier

Kim, M., Ma, D. J., Calligaris, D., Zhang, S., Feathers, R. W., Vaubel, R. A., Meaux, I., Mladek, A. C., Parrish, K. E., Jin, F., Barriere, C., Debussche, L., Watters, J., Tian, S., Decker, P. A., Eckel-Passow, J. E., Kitange, G. J., Johnson, A. J., Parney, I. F., Anastasiadis, P. Z. & 3 others, Agar, N. Y. R., Elmquist, W. F. & Sarkaria, J. N., Sep 1 2018, In : Molecular Cancer Therapeutics. 17, 9, p. 1893-1901 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Pharmaceutical Preparations
Gadolinium
Precision Medicine
1 Citation (Scopus)

Human perforin gene variation is geographically distributed

Willenbring, R. C., Ikeda, Y. H., Pease, L. R. & Johnson, A. J., Jan 1 2018, In : Molecular Genetics and Genomic Medicine. 6, 1, p. 44-55 12 p.

Research output: Contribution to journalArticle

Perforin
Mutation
Genes
Databases
Exome
2 Citations (Scopus)

Immunomodulation mediated by anti-angiogenic therapy improves CD8 T cell immunity against experimental glioma

Malo, C. S., Khadka, R. H., Ayasoufi, K., Jin, F., AbouChehade, J. E., Hansen, M. J., Iezzi, R., Pavelko, K. D. & Johnson, A. J., Aug 20 2018, In : Frontiers in Oncology. 8, AUG, 320.

Research output: Contribution to journalArticle

Immunomodulation
Glioma
Immunity
T-Lymphocytes
Glioblastoma
8 Citations (Scopus)

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Randall, E. C., Emdal, K. B., Laramy, J. K., Kim, M., Roos, A., Calligaris, D., Regan, M. S., Gupta, S. K., Mladek, A. C., Carlson, B. L., Johnson, A. J., Lu, F. K., Xie, X. S., Joughin, B. A., Reddy, R. J., Peng, S., Abdelmoula, W. M., Jackson, P. R., Kolluri, A., Kellersberger, K. A. & 8 others, Agar, J. N., Lauffenburger, D. A., Swanson, K., Tran, N., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., Dec 1 2018, In : Nature Communications. 9, 1, 4904.

Research output: Contribution to journalArticle

Pharmacodynamics
Pharmacokinetics
Glioblastoma
Heterografts
drugs
9 Citations (Scopus)

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells

Burrack, K. S., Huggins, M. A., Taras, E., Dougherty, P., Henzler, C. M., Yang, R., Alter, S., Jeng, E. K., Wong, H. C., Felices, M., Cichocki, F., Miller, J. S., Hart, G. T., Johnson, A. J., Jameson, S. C. & Hamilton, S. E., Jan 1 2018, (Accepted/In press) In : Immunity.

Research output: Contribution to journalArticle

Cerebral Malaria
Interleukin-15
Natural Killer Cells
Interleukin-10
Blood-Brain Barrier
4 Citations (Scopus)

Non-equivalent antigen presenting capabilities of dendritic cells and macrophages in generating brain-infiltrating CD8 + T cell responses

Malo, C. S., Huggins, M. A., Goddery, E. N., Tolcher, H. M. A., Renner, D. N., Jin, F., Hansen, M. J., Pease, L. R., Pavelko, K. D. & Johnson, A. J., Dec 1 2018, In : Nature Communications. 9, 1, 633.

Research output: Contribution to journalArticle

macrophages
T-cells
Macrophages
antigens
Dendritic Cells
2017
2 Citations (Scopus)

Brain atrophy in picornavirus-infected FVB mice is dependent on the H-2Db class i molecule

Kelcher, A. M. H., Atanga, P. A., Gamez, J. D., Garcia, L. M. C., Teclaw, S. J., Pavelko, K. D., Macura, S. I. & Johnson, A. J., Jun 1 2017, In : FASEB Journal. 31, 6, p. 2267-2275 9 p.

Research output: Contribution to journalArticle

Picornaviridae
Viruses
Atrophy
Brain
Theilovirus
26 Citations (Scopus)

Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment

Hardcastle, J., Mills, L., Malo, C. S., Jin, F., Kurokawa, C., Geekiyanage, H., Schroeder, M., Sarkaria, J. N., Johnson, A. J. & Galanis, E., Apr 1 2017, In : Neuro-Oncology. 19, 4, p. 493-502 10 p.

Research output: Contribution to journalArticle

Programmed Cell Death 1 Receptor
Measles virus
Glioblastoma
Antibodies
Glioma
9 Citations (Scopus)

Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane

Kumar, R., De Mooij, T., Peterson, T. E., Kaptzan, T., Johnson, A. J., Daniels, D. & Parney, I. F., Jun 1 2017, In : PLoS One. 12, 6, e0179012.

Research output: Contribution to journalArticle

suppressor cells
Conditioned Culture Medium
Glioma
Macrophage Migration-Inhibitory Factors
Monocytes
13 Citations (Scopus)

Perforin expression by CD8 T cells is sufficient to cause fatal brain edema during experimental cerebral malaria

Huggins, M. A., Johnson, H. L., Jin, F., N'Songo, A., Hanson, L. M., LaFrance, S. J., Butler, N. S., Harty, J. T. & Johnson, A. J., May 1 2017, In : Infection and Immunity. 85, 5, e00985-16.

Research output: Contribution to journalArticle

Cerebral Malaria
Perforin
Brain Edema
T-Lymphocytes
Edema
2016

CD74/DQA1 dimers predispose to the development of arthritis in humanized mice

David, L., Gokhale, A., Jois, S., Johnson, A. J., Behrens, M., Luthra, H. & Taneja, V. D., Feb 1 2016, In : Immunology. 147, 2, p. 204-211 8 p.

Research output: Contribution to journalArticle

Arthritis
Rheumatoid Arthritis
Collagen Type II
Alleles
Antigens
28 Citations (Scopus)

Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1

Kim, T. D., Jin, F., Shin, S., Oh, S., Lightfoot, S. A., Grande, J. P., Johnson, A. J., Van Deursen, J., Wren, J. D. & Janknecht, R., Feb 1 2016, In : Journal of Clinical Investigation. 126, 2, p. 706-720 15 p.

Research output: Contribution to journalArticle

Histone Demethylases
Prostate
Carcinogenesis
Transcription Factors
Prostatic Neoplasms
10 Citations (Scopus)

Improved Treatment Efficacy of Antiangiogenic Therapy when Combined with Picornavirus Vaccination in the GL261 Glioma Model

Renner, D. N., Malo, C. S., Jin, F., Parney, I. F., Pavelko, K. D. & Johnson, A. J., Jan 1 2016, In : Neurotherapeutics. 13, 1, p. 226-236 11 p.

Research output: Contribution to journalArticle

Picornaviridae
Glioma
Vaccination
Tumor Microenvironment
Tumor Burden
5 Citations (Scopus)

Modulatory effects of perforin gene dosage on pathogen-associated blood-brain barrier (BBB) disruption

Willenbring, R. C., Jin, F., Hinton, D. J., Hansen, M., Choi, D. S., Pavelko, K. D. & Johnson, A. J., Aug 31 2016, In : Journal of Neuroinflammation. 13, 1, 222.

Research output: Contribution to journalArticle

Perforin
Gene Dosage
Blood-Brain Barrier
Capillary Permeability
Theilovirus
4 Citations (Scopus)

Superior isolation of antigen-specific brain infiltrating T cells using manual homogenization technique

Cumba Garcia, L. M., Huseby Kelcher, A. M., Malo, C. S. & Johnson, A. J., Dec 1 2016, In : Journal of Immunological Methods. 439, p. 23-28 6 p.

Research output: Contribution to journalArticle

Theilovirus
Lymphocytes
T-Lymphocytes
Antigens
Brain
3 Citations (Scopus)

The effect of vector silencing during picornavirus vaccination against experimental melanoma and glioma

Malo, C. S., Renner, D. N., Huseby Kelcher, A. M., Jin, F., Hansen, M. J., Pavelko, K. D. & Johnson, A. J., Aug 1 2016, In : PLoS One. 11, 8, e0162064.

Research output: Contribution to journalArticle

Picornaviridae
Experimental Melanomas
T-cells
melanoma
Glioma
2015
2 Citations (Scopus)

A versatile simple capture assay for assessing the structural integrity of MHC multimer reagents

Reed, B. K., Chopp, L. B., Malo, C. S., Renner, D. N., Van Keulen, V. S., Girtman, M. A., Nevala, W. N., Pavelko, K. D., Gil, D., Schrum, A. G., Johnson, A. J. & Pease, L. R., Sep 21 2015, In : PLoS One. 10, 9, e0137984.

Research output: Contribution to journalArticle

T-cells
Structural integrity
Assays
T-Lymphocytes
Peptides
8 Citations (Scopus)

Correlation of Brain Atrophy, Disability, and Spinal Cord Atrophy in a Murine Model of Multiple Sclerosis

Paz Soldán, M. M., Raman, M. R., Gamez, J. D., Lohrey, A. K., Chen, Y., Pirko, I. & Johnson, A. J., Jul 1 2015, In : Journal of Neuroimaging. 25, 4, p. 595-599 5 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Atrophy
Spinal Cord
Brain
Rotarod Performance Test
14 Citations (Scopus)

Effective treatment of established GL261 murine gliomas through picornavirus vaccination-enhanced tumor antigen-specific CD8+ T cell responses

Renner, D. N., Jin, F., Litterman, A. J., Balgeman, A. J., Hanson, L. M., Gamez, J. D., Chae, M., Carlson, B. L., Sarkaria, J. N., Parney, I. F., Ohlfest, J. R., Pirko, I., Pavelko, K. D. & Johnson, A. J., May 1 2015, In : PLoS One. 10, 5, e0125565.

Research output: Contribution to journalArticle

Picornaviridae
T-cells
Neoplasm Antigens
Glioma
Tumors
16 Citations (Scopus)

Increasing glioma-associated monocytes leads to increased intratumoral and systemic myeloid-derived suppressor cells in a murine model

Chae, M., Peterson, T. E., Balgeman, A., Chen, S., Zhang, L., Renner, D. N., Johnson, A. J. & Parney, I. F., Jul 1 2015, In : Neuro-Oncology. 17, 7, p. 978-991 14 p.

Research output: Contribution to journalArticle

Glioma
Monocytes
Ovalbumin
Glioblastoma
Green Fluorescent Proteins
9 Citations (Scopus)

Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes

Papadakis, K., Krempski, J., Reiter, J., Svingen, P., Xiong, Y., Sarmento, O. F., Huseby, A., Johnson, A. J., Lomberk, G. A., Urrutia, R. A. & Faubion, W. A., 2015, In : American Journal of Physiology - Cell Physiology. 308, 5, p. C362-C371

Research output: Contribution to journalArticle

Growth Factor Receptors
Transforming Growth Factors
T-Lymphocytes
Spleen
Theilovirus
2014
4 Citations (Scopus)

A CD8 T-cell epitope variant enhances immune targeting to a recombinant picornavirus vaccine antigen

Bell, M. P., Renner, D. N., Johnson, A. J. & Pavelko, K. D., Sep 1 2014, In : Viral Immunology. 27, 7, p. 361-366 6 p.

Research output: Contribution to journalArticle

Picornaviridae
Synthetic Vaccines
T-Lymphocyte Epitopes
Viruses
Antigens
2 Citations (Scopus)

An elite controller of picornavirus infection targets an epitope that is resistant to immune escape

Bell, M. P., Renner, D. N., Johnson, A. J. & Pavelko, K. D., Apr 7 2014, In : PLoS One. 9, 4, e94332.

Research output: Contribution to journalArticle

Picornaviridae Infections
Picornaviridae
Viruses
epitopes
Epitopes
13 Citations (Scopus)

Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption

Johnson, H. L., Willenbring, R. C., Jin, F., Manhart, W. A., La France, S. J., Pirko, I. & Johnson, A. J., Oct 22 2014, In : PLoS One. 9, 10, A1805.

Research output: Contribution to journalArticle

Perforin
blood-brain barrier
T-cells
Blood-Brain Barrier
T-lymphocytes
10 Citations (Scopus)

Theiler's murine encephalomyelitis virus as an experimental model system to study the mechanism of blood-brain barrier disruption

Johnson, H. L., Jin, F., Pirko, I. & Johnson, A. J., 2014, In : Journal of NeuroVirology. 20, 2, p. 107-112 6 p.

Research output: Contribution to journalArticle

Theilovirus
Blood-Brain Barrier
Theoretical Models
T-Lymphocytes
Perforin
2013
1 Citation (Scopus)

Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption

Johnson, H. L., Hanson, L. M., Chen, Y., Bieber, A. J., Buono, R. J., Ferraro, T. N., Pirko, I. & Johnson, A. J., Oct 3 2013, In : BMC Genomics. 14, 1, 678.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Capillary Permeability
Genetic Association Studies
Blood-Brain Barrier
T-Lymphocytes
2012
1 Citation (Scopus)

Adapting a PET Imaging Agent for Correlative Microscopy of Meningiomas and Other Intracranial Tumors

Lingle, W. L., Negron, V., Johnson, G. B., Nathan, M. A., Parasi, J. E., Johnson, A. J., Hunt, C. H., Peller, P. J., Broski, S., Fauq, A. H., Jack, C. R. J., Petersen, R. C., Klunk, W. E., Mathis, C. A. & Lowe, V., 2012, In : Microscopy and Microanalysis. 18, p. 178-179 2 p.

Research output: Contribution to journalArticle

Tumors
Microscopic examination
tumors
microscopy
Imaging techniques
8 Citations (Scopus)

A hematopoietic contribution to microhemorrhage formation during antiviral CD8 T cell-initiated blood-brain barrier disruption

Johnson, H. L., Chen, Y., Suidan, G. L., McDole, J. R., Lohrey, A. K., Hanson, L. M., Jin, F., Pirko, I. & Johnson, A. J., Mar 27 2012, In : Journal of Neuroinflammation. 9, 60.

Research output: Contribution to journalArticle

129 Strain Mouse
Capillary Permeability
Blood-Brain Barrier
Antiviral Agents
Central Nervous System
24 Citations (Scopus)

CD8 T cell-initiated blood-brain barrier disruption is independent of neutrophil support

Johnson, H. L., Chen, Y., Jin, F., Hanson, L. M., Gamez, J. D., Pirko, I. & Johnson, A. J., Aug 15 2012, In : Journal of Immunology. 189, 4, p. 1937-1945 9 p.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Capillary Permeability
Neutrophils
T-Lymphocytes
Tight Junction Proteins
12 Citations (Scopus)

CMV infection attenuates the disease course in a murine model of multiple sclerosis

Pirko, I., Cardin, R., Chen, Y., Lohrey, A. K., Lindquist, D. M., Dunn, R. S., Zivadinov, R. & Johnson, A. J., Feb 29 2012, In : PLoS One. 7, 2, e32767.

Research output: Contribution to journalArticle

Encephalitis Viruses
sclerosis
Viruses
disease course
Multiple Sclerosis
5 Citations (Scopus)

Contrasting roles for CD4 vs. CD8 T-cells in a murine model of virally induced "T1 black hole" formation

Pirko, I., Chen, Y., Lohrey, A. K., McDole, J., Gamez, J. D., Allen, K. S., Pavelko, K. D., Lindquist, D. M., Dunn, R. S., Macura, S. I. & Johnson, A. J., Feb 13 2012, In : PLoS One. 7, 2, e31459.

Research output: Contribution to journalArticle

T-cells
T-lymphocytes
animal models
T-Lymphocytes
Magnetic resonance imaging
4 Citations (Scopus)

Depletion of GR-1-Positive Cells Is Associated with Reduced Neutrophil Inflammation and Astrocyte Reactivity after Experimental Intracerebral Hemorrhage

Loftspring, M. C., Johnson, H. L., Johnson, A. J. & Clark, J. F., Jul 2012, In : Translational Stroke Research. 3, SUPPL. 1, p. 147-154 8 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Astrocytes
Neutrophils
Brain Injuries
Inflammation
4 Citations (Scopus)

Nonequivalence of classical MHC class I loci in ability to direct effective antiviral immunity

Pavelko, K. D., Mendez-Fernandez, Y., Bell, M. P., Hansen, M. J., Johnson, A. J., David, C. S., Rodriguez, M. & Pease, L. R., Feb 2012, In : PLoS Pathogens. 8, 2, e1002541.

Research output: Contribution to journalArticle

Antiviral Agents
Immunity
Demyelinating Diseases
Transgenes
Virus Diseases
11 Citations (Scopus)

Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability

Suidan, G. L., Dickerson, J. W., Johnson, H. L., Chan, T. W., Pavelko, K. D., Pirko, I., Seroogy, K. B. & Johnson, A. J., Sep 18 2012, In : Journal of Neuroinflammation. 9, 218.

Research output: Contribution to journalArticle

Neuropilin-1
Capillary Permeability
Blood-Brain Barrier
Blood Vessels
Central Nervous System
2011
27 Citations (Scopus)

Brain atrophy correlates with functional outcome in a murine model of multiple sclerosis

Pirko, I., Johnson, A. J., Chen, Y., Lindquist, D. M., Lohrey, A. K., Ying, J. & Dunn, R. S., Jan 15 2011, In : NeuroImage. 54, 2, p. 802-806 5 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Atrophy
Brain
Encephalitis Viruses
Rotarod Performance Test
36 Citations (Scopus)

Modulation of peripheral cytotoxic cells and ictogenesis in a model of seizures

Marchi, N., Johnson, A. J., Puvenna, V., Johnson, H. L., Tierney, W., Ghosh, C., Cucullo, L., Fabene, P. F. & Janigro, D., Sep 2011, In : Epilepsia. 52, 9, p. 1627-1634 8 p.

Research output: Contribution to journalArticle

Pilocarpine
Seizures
Perforin
Splenectomy
Status Epilepticus
156 Citations (Scopus)

The relevance of animal models in multiple sclerosis research

Denic, A., Johnson, A. J., Bieber, A. J., Warrington, A. E., Rodriguez, M. & Pirko, I., Feb 2011, In : Pathophysiology. 18, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

Demyelinating Diseases
Multiple Sclerosis
Animal Models
Autoimmune Experimental Encephalomyelitis
Theilovirus
29 Citations (Scopus)

Unconjugated bilirubin contributes to early inflammation and edema after intracerebral hemorrhage

Loftspring, M. C., Johnson, H. L., Feng, R., Johnson, A. J. & Clark, J. F., Apr 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 4, p. 1133-1142 10 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Bilirubin
Edema
Inflammation
Brain Injuries
2010
45 Citations (Scopus)

CD8 T cell-initiated vascular endothelial growth factor expression promotes central nervous system vascular permeability under neuroinflammatory conditions

Suidan, G. L., Dickerson, J. W., Chen, Y., McDole, J. R., Tripathi, P., Pirko, I., Seroogy, K. B. & Johnson, A. J., Jan 15 2010, In : Journal of Immunology. 184, 2, p. 1031-1040 10 p.

Research output: Contribution to journalArticle

Capillary Permeability
Vascular Endothelial Growth Factor A
Central Nervous System
T-Lymphocytes
Blood-Brain Barrier
18 Citations (Scopus)

Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells

McDole, J. R., Danzer, S. C., Pun, R. Y. K., Chen, Y., Johnson, H. L., Pirko, I. & Johnson, A. J., Oct 2010, In : American Journal of Pathology. 177, 4, p. 1823-1833 11 p.

Research output: Contribution to journalArticle

Theilovirus
Central Nervous System
T-Lymphocytes
Neurons
Viruses
2009
26 Citations (Scopus)

Deep gray matter T2 hypointensity correlates with disability in a murine model of MS

Pirko, I., Johnson, A. J., Lohrey, A. K., Chen, Y. & Ying, J., Jul 15 2009, In : Journal of the Neurological Sciences. 282, 1-2, p. 34-38 5 p.

Research output: Contribution to journalArticle

Theilovirus
Cerebellar Nuclei
Putamen
Thalamus
Multiple Sclerosis
35 Citations (Scopus)

Intracerebral hemorrhage leads to infiltration of several leukocyte populations with concomitant pathophysiological changes

Loftspring, M. C., McDole, J., Lu, A., Clark, J. F. & Johnson, A. J., Jan 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 1, p. 137-143 7 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Leukocytes
Population
Immune System
Flow Cytometry
2008
23 Citations (Scopus)

Acute hemorrhagic demyelination in a murine model of multiple sclerosis

Pirko, I., Suidan, G. L., Rodriguez, M. & Johnson, A. J., Jul 7 2008, In : Journal of Neuroinflammation. 5, 31.

Research output: Contribution to journalArticle

Encephalitis Viruses
Demyelinating Diseases
Multiple Sclerosis
Inbred C57BL Mouse
Rotarod Performance Test
4 Citations (Scopus)

A translatable molecular approach to determining CD8 T-cell epitopes in TMEV infection

McDole, J., Suidan, G., Boespflug, E., Cheng, J., Chen, Y., Pirko, I. & Johnson, A. J., Nov 2008, In : Human Immunology. 69, 11, p. 805-810 6 p.

Research output: Contribution to journalArticle

Theilovirus
T-Lymphocyte Epitopes
Virus Diseases
Epitopes
T-Cell Antigen Receptor Specificity
69 Citations (Scopus)

Induction of blood brain barrier tight junction protein alterations by CD8 T cells

Suidan, G. L., Mcdole, J. R., Chen, Y., Pirko, I. & Johnson, A. J., Aug 22 2008, In : PLoS One. 3, 8, e3037.

Research output: Contribution to journalArticle

Tight Junction Proteins
blood-brain barrier
tight junctions
T-cells
Neurology
20 Citations (Scopus)

Multiple sclerosis: Pathogenesis and MR imaging features of T1 hypointensities in murine model

Pirko, I., Nolan, T. K., Holland, S. K. & Johnson, A. J., Mar 2008, In : Radiology. 246, 3, p. 790-795 6 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Fas Ligand Protein
Inbred C57BL Mouse
Transcriptional Activation